Structure-based drug design strategies in medicinal
... The search for new biologically active molecules from large compound databases by means of computer-assisted methods is a process known as virtual screening. VS methods have rapidly become an essential component of the modern drug discovery process [24-27]. Structure-based virtual screening (SBVS) a ...
... The search for new biologically active molecules from large compound databases by means of computer-assisted methods is a process known as virtual screening. VS methods have rapidly become an essential component of the modern drug discovery process [24-27]. Structure-based virtual screening (SBVS) a ...
17.Ramdas T. Dolas, Dr. Avinash Hosmani and Sachin B. Somwanshi
... INTRODUCTION In recent years there has been a growing interest in the development, design and evaluation of sustained or controlled release systems. Many controlled release systems have been developed for maintaining a therapeutically effective concentration of drug in systemic circulation for longe ...
... INTRODUCTION In recent years there has been a growing interest in the development, design and evaluation of sustained or controlled release systems. Many controlled release systems have been developed for maintaining a therapeutically effective concentration of drug in systemic circulation for longe ...
DRUG INTERACTIONS
... has a powerful potential as a teratogen, the mechanism whereby it exerts this potential is unknown. If it is given to mothers during the initial period of gestation when the limb buds are forming, results in sealed limbs. Another diosyncratic reaction is drug induced cancer. Because of long inductio ...
... has a powerful potential as a teratogen, the mechanism whereby it exerts this potential is unknown. If it is given to mothers during the initial period of gestation when the limb buds are forming, results in sealed limbs. Another diosyncratic reaction is drug induced cancer. Because of long inductio ...
Introduction - KSU Faculty Member websites
... The label must also list each ingredient by name, quantity, and total weight and must identify the plant parts from which each ingredient is derived (11). Most dietary supplements used in alternative medicine are derived from plants; some are derived from animals. Because such dietary supplements ar ...
... The label must also list each ingredient by name, quantity, and total weight and must identify the plant parts from which each ingredient is derived (11). Most dietary supplements used in alternative medicine are derived from plants; some are derived from animals. Because such dietary supplements ar ...
National Essential Anaesthesia Drug List (NEADL) 2015.
... An important purpose of NEADL is to advise suppliers and managers of a minimum set of drugs that must be available wherever anaesthesia is to be conducted safely. Efforts can then be focused to ensure sustainability of their supply. Consultant anaesthetists may well find that other drugs are preferr ...
... An important purpose of NEADL is to advise suppliers and managers of a minimum set of drugs that must be available wherever anaesthesia is to be conducted safely. Efforts can then be focused to ensure sustainability of their supply. Consultant anaesthetists may well find that other drugs are preferr ...
doc Notes on Lecture 2
... that they wish there were drug stores that had all manner of materials people used to by bolsom for colds people bought what was available there used to be a bunch of over the top dramatic adds but that would sell product eg. Wolcott’s instant pain annihilator eg. Parker’s tonic beet alcohol eg. T ...
... that they wish there were drug stores that had all manner of materials people used to by bolsom for colds people bought what was available there used to be a bunch of over the top dramatic adds but that would sell product eg. Wolcott’s instant pain annihilator eg. Parker’s tonic beet alcohol eg. T ...
Medication Safety for the Elderly: A Guide for Patients
... cold symptoms. However, each year many older Americans are hospitalized because of problems related to nonprescription medications. Here are some potential problems: • Seniors taking one or more prescription medicines may take a nonprescription medicine that causes the same effect (for example, lowe ...
... cold symptoms. However, each year many older Americans are hospitalized because of problems related to nonprescription medications. Here are some potential problems: • Seniors taking one or more prescription medicines may take a nonprescription medicine that causes the same effect (for example, lowe ...
copyright 1 Introduction to dosage form design
... Anticancer drugs are notoriously nonselective in their cytotoxic effects; however, drug delivery systems may be designed to selectively target tumor cells with known biological features. Drug delivery systems can be developed to address the challenges that drugs present: poor solubility, large molec ...
... Anticancer drugs are notoriously nonselective in their cytotoxic effects; however, drug delivery systems may be designed to selectively target tumor cells with known biological features. Drug delivery systems can be developed to address the challenges that drugs present: poor solubility, large molec ...
PDF full-Text - Journal of Investigational Allergology and Clinical
... Humans are exposed to different foreign and artificially synthesized chemical substances, toxic products of natural origin, or drugs (xenobiotics). In response to such chemical agents, the body does not generate specific degradation and excretion mechanisms for each particular molecule. In a quest f ...
... Humans are exposed to different foreign and artificially synthesized chemical substances, toxic products of natural origin, or drugs (xenobiotics). In response to such chemical agents, the body does not generate specific degradation and excretion mechanisms for each particular molecule. In a quest f ...
Unwanted Interactions Among Most Common
... including intravenous immunoglobulin (IVIG),14 with little attention to unwanted drug-drug or drug-supplement interactions. Moreover, in many cases, as in the use of IVIG, there is a lack of well-designed double-blind studies,15 so there should be continued vigilance for the possible development of ...
... including intravenous immunoglobulin (IVIG),14 with little attention to unwanted drug-drug or drug-supplement interactions. Moreover, in many cases, as in the use of IVIG, there is a lack of well-designed double-blind studies,15 so there should be continued vigilance for the possible development of ...
Journal of Pharmacognosy and Phytochemistry Moringa Perspective
... economic benefits. This review focuses on the bio-prospects of Moringa particularly on relatively little explored area of their microbiological applications Keyword: Applied microbiology, Antimicrobials, Moringa species. ...
... economic benefits. This review focuses on the bio-prospects of Moringa particularly on relatively little explored area of their microbiological applications Keyword: Applied microbiology, Antimicrobials, Moringa species. ...
WHY ARE WE STILL STUCK AROUND BENZODIAZEPINES? Introduction SMMGP Manchester, October 2013
... also provoke a specific deficit in new memory formation May lead to memory lapses or ‘blackouts’, when patients may do something under the influence of BZs they don’t recall (transient global amnesia) Chronic effects on memory are likely to result in reduced social functioning over time, e.g. reduce ...
... also provoke a specific deficit in new memory formation May lead to memory lapses or ‘blackouts’, when patients may do something under the influence of BZs they don’t recall (transient global amnesia) Chronic effects on memory are likely to result in reduced social functioning over time, e.g. reduce ...
who drug information - World Health Organization
... Throughout the past year the World Health Organization has continued to consult both national regulatory authorities and organizations representative of the pharmaceutical industry on the implementation of the WHO Certification Scheme on the Quality of Pharmaceutical Products moving in International ...
... Throughout the past year the World Health Organization has continued to consult both national regulatory authorities and organizations representative of the pharmaceutical industry on the implementation of the WHO Certification Scheme on the Quality of Pharmaceutical Products moving in International ...
lecture6-Quantitative aspect of drugs 12-132014-08
... When low → the drug has a narrow margin of safety →digoxin ...
... When low → the drug has a narrow margin of safety →digoxin ...
Dr. A. Ramkishan- CDSCO WHO TRS WPU
... the quality of drugs moving in the market by carrying out post market ...
... the quality of drugs moving in the market by carrying out post market ...
pharma 2
... A graph show the effects of somatostatin (the doc. read them all but the most important function is the inhibition of GHs ) Also one of its other functions is inhibiting GIT motility = stop the diarrhea ...
... A graph show the effects of somatostatin (the doc. read them all but the most important function is the inhibition of GHs ) Also one of its other functions is inhibiting GIT motility = stop the diarrhea ...
ANTI-PSYCHOTIC DRUGS
... Less pervasive psychiatric disorders Comprehend reality, suffering & disability are sometimes severe Acute or transient, persistent or recurrent Mood changes- anxiety , panic, depression Limited abnormalities of thought- obsessions, irrational fears Behavior – rituals, compulsions, hysterical conver ...
... Less pervasive psychiatric disorders Comprehend reality, suffering & disability are sometimes severe Acute or transient, persistent or recurrent Mood changes- anxiety , panic, depression Limited abnormalities of thought- obsessions, irrational fears Behavior – rituals, compulsions, hysterical conver ...
cnspharmacology
... The drugs that selectively modify CNS function act either specifically or nonspecifically according to its effect or response. For example, the effect of the drug is specific when it binds to a target cell’s receptors and affects an identifiable intracellular mechanism and imparts a specific therape ...
... The drugs that selectively modify CNS function act either specifically or nonspecifically according to its effect or response. For example, the effect of the drug is specific when it binds to a target cell’s receptors and affects an identifiable intracellular mechanism and imparts a specific therape ...
Drugs found in the drug tray
... (as assessed by awakening time, time needed to follow simple commands and time to perform simple tests after anesthesia as well as they were performed before anesthesia), based upon data derived from short operative procedures where intravenous etomidate was used for both induction and maintenance o ...
... (as assessed by awakening time, time needed to follow simple commands and time to perform simple tests after anesthesia as well as they were performed before anesthesia), based upon data derived from short operative procedures where intravenous etomidate was used for both induction and maintenance o ...
Review Drug chirality: a consideration of the significance
... A survey of 1675 drugs carried out in the early 1980s, indicated that 1200 (71.6%) could be classified as synthetic and 475 (28.4%) as natural products or semisynthetic agents. Four hundred and eighty (28.7%) of the synthetic compounds were chiral and of these 58 (3.5%) were marketed as single isome ...
... A survey of 1675 drugs carried out in the early 1980s, indicated that 1200 (71.6%) could be classified as synthetic and 475 (28.4%) as natural products or semisynthetic agents. Four hundred and eighty (28.7%) of the synthetic compounds were chiral and of these 58 (3.5%) were marketed as single isome ...
Revised: June 2014 AN: 00198/2014 SUMMARY OF PRODUCT
... Do not use in case of hypersensitivity to the active substance, or to any of the excipients. 4.4 Special warnings for each target species Treatment of Mycoplasma spp infections may not eradicate the organism. 4.5 Special precautions for use (i) ...
... Do not use in case of hypersensitivity to the active substance, or to any of the excipients. 4.4 Special warnings for each target species Treatment of Mycoplasma spp infections may not eradicate the organism. 4.5 Special precautions for use (i) ...
Treatment of drug dependence What you need to know
... or for longer periods of time. They have become a bigger issue in recent years due to their availability online. The risks associated with “black market” benzodiazepines are huge due to the uncertainty of what they contain. They may contain more or less than the advertised amount of drug, a differen ...
... or for longer periods of time. They have become a bigger issue in recent years due to their availability online. The risks associated with “black market” benzodiazepines are huge due to the uncertainty of what they contain. They may contain more or less than the advertised amount of drug, a differen ...
How Alcohol Enters the Body
... effects are not apparent. Mildly relaxed and maybe a little lightheaded. 0.04 — 0.06 BAC: Feeling of well-being, relaxation, lower inhibitions, sensation of warmth. Euphoria. Some minor impairment of reasoning and memory, lowering of caution. Your behavior may become exaggerated and emotions intensi ...
... effects are not apparent. Mildly relaxed and maybe a little lightheaded. 0.04 — 0.06 BAC: Feeling of well-being, relaxation, lower inhibitions, sensation of warmth. Euphoria. Some minor impairment of reasoning and memory, lowering of caution. Your behavior may become exaggerated and emotions intensi ...
... The dissolution rate of selected prepared formulations F2 and F8 were compared with that of marketed conventional tablet. The F8 formulation shown prolonged release (86%) up to 12 hrs, but the marketed tablet released 97% of drug within 2.5 hrs. Further, to confirm the mechanism of drug release, F2 ...
Pharmacognosy
Pharmacognosy is the study of medicinal drugs derived from plants or other natural sources. The American Society of Pharmacognosy defines pharmacognosy as ""the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources.""It is also defined as the study of crude drugs.