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- Journal of SOPI
- Journal of SOPI

... According to WHO, “Herbal medicines include herbs, herbal materials, herbal preparations, and finished herbal products.” In developing and underdeveloped countries, about 80% of the population depends on traditional system of medicine for primary health care. Traditional medicine practices have been ...
Discovering drug interactions: a text
Discovering drug interactions: a text

... Common drug-drug interactions involve how drugs are metabolized by the body. Metabolism-based interactions mainly happen in the liver as most of the drugs are metabolized by enzymes that reside in the liver. A drug is expected to be eliminated by the body within a certain amount of time after being ...
Addiction and Recovery 101
Addiction and Recovery 101

... to be reliable in their efforts to provide information that is complete and generally in accord with the standards accepted at the time of publication. However, in view of the possibility of human error or changes in medical sciences, neither the author nor the publisher nor any other party who has ...
O A
O A

... The objective of this study was to conduct antihyperglycemic and antinociceptive activity studies with methanolic extract of rhizomes of Kaempferia rotunda, a plant used in folk medicines of Bangladesh for treatment of high blood sugar level and pain. Antihyperglycemic activity studies were conducte ...
Bioactivity of Peptides…
Bioactivity of Peptides…

... Although many peptide/protein like products are generally designed for parenteral administration, some other noninvasive routes have also been used. e.g. desmopressin is delivered nasally and deoxyribonuclease by inhalation. Although peptides and proteins are generally orally inactive, cyclosporine ...
Antimalarial Drugs Malaria
Antimalarial Drugs Malaria

... a causal prophylactic while visiting CQresistant/multidrugresistant P.f. endemic areas. ...
Adminstering Medications
Adminstering Medications

... e. Ointments are the thickest form of topical medication.  The ...
pps
pps

... Modern Methods in Drug Discovery WS09/10 ...
a55f476935070a0
a55f476935070a0

... Digoxin is an inotropic agent primarily used to treat CHF and atrial fibrillation. It is incompletely absorbed and once absorbed a substantial fraction is cleared by kidneys . in the acute care seting historically digoxin loading dose of = 1 mg/70 kg were administered before the initiation of the us ...
“Design and Development of Alfuzosin Hydrochloride Floating Tablet.”
“Design and Development of Alfuzosin Hydrochloride Floating Tablet.”

... drug release at 1,6,12 and 20 hours; floating lag time; diffusion exponent (n) and release rate constant were selected as dependent variable. Formulations were evaluated for their physical properties, drug content and in vitro drug release. All formulations had good physical integrity. Drug release ...
Evidence-based treatment for drug misuse, with special reference to
Evidence-based treatment for drug misuse, with special reference to

... Only limited international efforts to control abuse of tramadol at an international scale. In 2007, China took vigorous measures against tramadol marketing; this was associated with eventual decreasing levels of misuse in the general population ...
Relevance of USP Methodology in the Development of a
Relevance of USP Methodology in the Development of a

... Hydrophilic matrices continue to be a growing area of interest to provide controlled drug delivery to the oral route. Factors that influence drug release through hydrophilic matrices have been extensively reviewed in the literature. Verapamil Hydrochloride (HCl) is a weakly basic drug which has been ...
July 2015 - Consumer Hearing on Biosimilars
July 2015 - Consumer Hearing on Biosimilars

... flagging might be considered appropriate for biosimilar and their reference medicines. The PBAC clearly noted that any such recommendations would be made on a case-by-case basis, by which PBAC meant that being a biosimilar in itself, did not mean it could automatically be ‘a’ flagged. The PBAC consi ...
Benzodiazepines
Benzodiazepines

...  As we learned in class:  1800’s looking for something other than alcohol to be used as CNSD  Bromides 1800s helpful but toxic  Barbiturates 1900s initially safe/effective; eventual problems with tolerance, safety and dependence  Benzodiazepines 1950s safe for short periods of time; long term u ...
What’s In this Urine?
What’s In this Urine?

... 0 to 21 days after  Target analyte: 9COOH-THC, the primary psychoactive use component of marijuana.  Peak plasma concentrations reached within 10 minutes of inhalation.  Passive inhalation is unlikely to be detected by this assay.  Hemp seed ingestion may produce a positive result.  Marinol is ...
ANTISEPSIS Aspects of history: Since the middle of XIX century the
ANTISEPSIS Aspects of history: Since the middle of XIX century the

... All these investments were achieved and their action verified in a surgical practice during various wars. Definition of antisepsis An antiseptic is a chemical agent that either kills pathogenic microorganisms or inhibits their growth so long as there is contact between agent and microorganism. The t ...
October
October

... a way to help deter the use of prescription drugs for illegal purposes. The system created is called the Prescription Monitoring Program (PMP). In 1990, Oklahoma became the first state in the United States to implement a computerized PMP. OBNDD has continued improving the system to make it more effe ...
drug product distribution requirements for pharmacy
drug product distribution requirements for pharmacy

... This document has two lists: Professional Service Area Items (Schedule II) and Professional Products Area Items (Schedule III). Within each list, drugs are categorized according to their common indications for use. These lists are meant to be used as a resource and are not exhaustive. The Drug Sched ...
One Step Multi-Drug Screen Test Card with Integrated E
One Step Multi-Drug Screen Test Card with Integrated E

... Opiate refers to any drug that is derived from the opium poppy, including the natural products, morphine and codeine, and the semi-synthetic drugs such as heroin. Opioid is more general, referring to any drug that acts on the opioid receptor. Opioid analgesics comprise a large group of substances wh ...
DEVELOPMENT AND IN­VITRO EVALUATION OF SALBUTAMOL SULPHATE MUCOADHESIVE  BUCCAL PATCHES  
DEVELOPMENT AND IN­VITRO EVALUATION OF SALBUTAMOL SULPHATE MUCOADHESIVE  BUCCAL PATCHES  

... effective  plasma  levels.  Because  of  the  low  tissue  permeability  for  compounds  such  as  peptides,  buccal  administration  is  then  often  ranked as less effective when compared to nasal delivery, and better  than  transdermal  delivery.  In  the  case  of  a  sufficiently  potent  pepti ...
This copy is for personal use only
This copy is for personal use only

... and acute hemolysis induced by anti-malaria drugs in patients with low glucose-6-phosphate-dehydrogenase (G6PD) activity – set the stage for new developments. By the end of the 80s, the causal genes coding for debrisoquine hydroxylase, or CYP2D6, had been cloned and characterized, inaugurating what ...
Advanced Pharmaceutics
Advanced Pharmaceutics

... Mesotherapy involves multiple intradermal or subcutaneous injections of a mixture of compounds (plant extracts, homeopathic agents, pharmaceuticals, vitamins, and other bioactive substances) in minute doses, using very fine gauge needles, to treat medical (mainly local) and cosmetic conditions. The ...
this PDF file
this PDF file

... In the spring of 1943, a 37-year-old Swiss chemist named Albert Hofmann had “a peculiar presentiment.” He believed that he had missed something in 1938, the year when he first synthesized the twenty-fifth compound of the lysergic acid diethylamide series, LSD-25. For eight years at Sandoz Pharmaceut ...
Prescription Drug Abuse: Insight Into the Epidemic
Prescription Drug Abuse: Insight Into the Epidemic

... in the literature, and certain terms overlap (Table 3). The terms “misuse” or “nonmedical use” are nonspecific and lend them­ selves to a broad range of interpretations; also, the terms are often employed interchangeably to encompass a diverse ­collection of behaviors and motives not intended by the ...
clinical safety data management
clinical safety data management

... healthy volunteer subjects or in patients with the target disease. In patients, if there is an appropriate measure, pharmacodynamic data can provide early estimates of activity and potential efficacy and may guide the dosage and dose regimen in later studies. d) Early Measurement of Drug Activity Pr ...
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Pharmacognosy



Pharmacognosy is the study of medicinal drugs derived from plants or other natural sources. The American Society of Pharmacognosy defines pharmacognosy as ""the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources.""It is also defined as the study of crude drugs.
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