fast dissolving tablets: preparation, characterization and evaluation
... forms existing today because of ease of self administration ,compact in nature, easy to manufacture and it can be deliver in accurate dose. One important drawback of solid dosage forms is the difficulty in swallowing (dysphagia) or chewing in some patients particularly pediatric and geriatric patien ...
... forms existing today because of ease of self administration ,compact in nature, easy to manufacture and it can be deliver in accurate dose. One important drawback of solid dosage forms is the difficulty in swallowing (dysphagia) or chewing in some patients particularly pediatric and geriatric patien ...
Research Article PRELIMINARY PHYTOCHEMICAL ANALYSIS, HPTLC STUDIES AND ANTIPYRETIC ACTIVITY HELICTERES ISORA
... Group2: Standard group (Paracetamol 150mg/kg body weight) p.o. Group3: Aqueous extract (200 mg/kg body weight) p.o. Group4: Aqueous extract (400mg/kg body weight) p.o. Group5: Alcohol extract (200mg/kg body weight) p.o. Group6: Alcohol extract (400 mg/kg body weight) p.o. The different gr ...
... Group2: Standard group (Paracetamol 150mg/kg body weight) p.o. Group3: Aqueous extract (200 mg/kg body weight) p.o. Group4: Aqueous extract (400mg/kg body weight) p.o. Group5: Alcohol extract (200mg/kg body weight) p.o. Group6: Alcohol extract (400 mg/kg body weight) p.o. The different gr ...
Fixed Dose Combinations & Rational Pharmacotherapeutics DR
... • FDCs of Nimesulide + Paracetamol : Nimesulide alone is more antipyretic than paracetamol, more antiinflammatory than aspirin, and equivalent in analgesia to any of the NSAIDS alone. Efficacy gains unlikely with added Paracetamol and pts are subjected to increased hepatotoxic effects from the combo ...
... • FDCs of Nimesulide + Paracetamol : Nimesulide alone is more antipyretic than paracetamol, more antiinflammatory than aspirin, and equivalent in analgesia to any of the NSAIDS alone. Efficacy gains unlikely with added Paracetamol and pts are subjected to increased hepatotoxic effects from the combo ...
entirely gone out useful plant –artemisia cina
... belong the drug known as cina in the Homeopathic Materia Media, held a prominent place among the medicinal substances of the ancient physicians, from Hippocrates to Scrapion. They were chiefly recommended as febrifuge, stomachic and anthelmintic. In modern times,under the allopa5thic school, cina ha ...
... belong the drug known as cina in the Homeopathic Materia Media, held a prominent place among the medicinal substances of the ancient physicians, from Hippocrates to Scrapion. They were chiefly recommended as febrifuge, stomachic and anthelmintic. In modern times,under the allopa5thic school, cina ha ...
Guidance for Clinical Investigators, Sponsors, and IRBs
... The definitions in the IND regulations describe specific roles for the individual or individuals who conduct a clinical investigation (the investigators) and the individual or entity who has primary responsibility for and initiates the clinical investigation (the sponsor) (§ 312.3(b)). In the most c ...
... The definitions in the IND regulations describe specific roles for the individual or individuals who conduct a clinical investigation (the investigators) and the individual or entity who has primary responsibility for and initiates the clinical investigation (the sponsor) (§ 312.3(b)). In the most c ...
Diuretics and Synthetic Hypoglycemic Drugs
... The hypoglycemic(降血糖)effect of salicylates(水杨酸 盐)has been known for 100 years. Clinical use of salicylates was not feasible, since the very large doses required produced intolerable side effects. The hypoglycemic effects of the thiadiazole sulfonamide known as IPTD, used to treat typhoid (伤 寒症)f ...
... The hypoglycemic(降血糖)effect of salicylates(水杨酸 盐)has been known for 100 years. Clinical use of salicylates was not feasible, since the very large doses required produced intolerable side effects. The hypoglycemic effects of the thiadiazole sulfonamide known as IPTD, used to treat typhoid (伤 寒症)f ...
Basics Pharmacology Review - Dr. Roland Halil
... (Partially adapted from slides by Marc Riachi, R.Ph.) ...
... (Partially adapted from slides by Marc Riachi, R.Ph.) ...
The Effect of Changes in Co-payment and Premium Policies
... What Did We Learn? 1. Policy makers should be very concerned about the potential for negative health outcomes from co-payment policies: The results of this study, and many others, show that co-payments reduce the use of both essential and less-essential drugs. Moreover, we found that co-payment poli ...
... What Did We Learn? 1. Policy makers should be very concerned about the potential for negative health outcomes from co-payment policies: The results of this study, and many others, show that co-payments reduce the use of both essential and less-essential drugs. Moreover, we found that co-payment poli ...
What clinical trial designs have been used to test antiepileptic drugs
... 1952). The dismal state of AED assessment deep into the 20th century is best testified by the Coatsworth report, published in 1971 by the US National Institute for Neurological Disorders and Stroke (NINDS). Out of 250 studies published up to 1970 on the efficacy of AEDs marketed in the US, only 110 fo ...
... 1952). The dismal state of AED assessment deep into the 20th century is best testified by the Coatsworth report, published in 1971 by the US National Institute for Neurological Disorders and Stroke (NINDS). Out of 250 studies published up to 1970 on the efficacy of AEDs marketed in the US, only 110 fo ...
Veterinary Dispensing Technician Educational Packet
... promote growth, improve meat quality in a sense of reducing fat and growing more muscles, and otherwise reduce production costs. With the agricultural use of drugs there is the potential of leaving residues that may appear in the food. Veterinary drug residues are the very small amounts of veterinar ...
... promote growth, improve meat quality in a sense of reducing fat and growing more muscles, and otherwise reduce production costs. With the agricultural use of drugs there is the potential of leaving residues that may appear in the food. Veterinary drug residues are the very small amounts of veterinar ...
WHAT IS NEW IN OSTEOARTHRITIS? SYSADOA CLINICAL REVIEW
... for months even after treatment suppression). Moreover, these drugs have a high safety profile and the ratio cost/effectiveness is low. The main SYSADOAs are chondroitin sulfate (CS), glucosamine sulfate (GLU) and hyaluronic acid (HA). They are specially indicated in elderly patients, often ...
... for months even after treatment suppression). Moreover, these drugs have a high safety profile and the ratio cost/effectiveness is low. The main SYSADOAs are chondroitin sulfate (CS), glucosamine sulfate (GLU) and hyaluronic acid (HA). They are specially indicated in elderly patients, often ...
Promoting rational use of medicines: core components
... resources – often out-of-pocket payments by patients – and result in significant patient harm in terms of poor patient outcomes and adverse drug reactions. Furthermore, over-use of antimicrobials is leading to increased antimicrobial resistance and non-sterile injections to the transmission of hepat ...
... resources – often out-of-pocket payments by patients – and result in significant patient harm in terms of poor patient outcomes and adverse drug reactions. Furthermore, over-use of antimicrobials is leading to increased antimicrobial resistance and non-sterile injections to the transmission of hepat ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) e-ISSN: 2278-3008, p-ISSN:2319-7676.
... Maceration process involves separation of medicinally active portions of the crude drugs. It is based on the immersion of the crude drugs in the bulk of solvent or menstrum. Solid drug material was taken in a stopperd container with about 750ml of the menstrum and allowed to stand for at least three ...
... Maceration process involves separation of medicinally active portions of the crude drugs. It is based on the immersion of the crude drugs in the bulk of solvent or menstrum. Solid drug material was taken in a stopperd container with about 750ml of the menstrum and allowed to stand for at least three ...
PIERIS PHARMACEUTICALS, INC.
... rate and degree that are of market based on acceptance management’s of anycurrent of our expectations approved drug and candidates; assumptions developments and are subject and to projections risks and relating uncertainties. to our In competitors some cases, and you ourcan industry; identifyour for ...
... rate and degree that are of market based on acceptance management’s of anycurrent of our expectations approved drug and candidates; assumptions developments and are subject and to projections risks and relating uncertainties. to our In competitors some cases, and you ourcan industry; identifyour for ...
floating bilayer tablet: a review - international journal of advances in
... personnel (as this is the case with most parent rally administered dosage forms). Oral route of administration involve oral controlled drug delivery which aims to deliver drug for an extensive period of time which provide good bioavailability and makes the dosage form reproducible. Conventional drug ...
... personnel (as this is the case with most parent rally administered dosage forms). Oral route of administration involve oral controlled drug delivery which aims to deliver drug for an extensive period of time which provide good bioavailability and makes the dosage form reproducible. Conventional drug ...
Sedatives Part II - People Server at UNCW
... Benzodiazepines have a fairly safe therapeutic index Rohypnol – Powerful benzo that is an amnestic. One of the unfortunately many date rape drugs. ...
... Benzodiazepines have a fairly safe therapeutic index Rohypnol – Powerful benzo that is an amnestic. One of the unfortunately many date rape drugs. ...
... three times daily, can provide significant commercial advantage and is worth patenting. Another useful follow-on patent may be the process by which a patented molecule is made. This is particularly useful for biological products that are difficult to make by non-recombinant methods. A follow-on pate ...
serum antioxidant parameters in patients poisoned by different
... (2,2-diphenyl-1-picrylhydrazyl, DPPH assay) in the blood serum. The major role of sulfhydryl groups lies also in stabilizing the three-dimensional structure of proteins, thereby preserving their functional properties. Sulfhydryls play an important role in biochemistry as disulfide bonds connect amin ...
... (2,2-diphenyl-1-picrylhydrazyl, DPPH assay) in the blood serum. The major role of sulfhydryl groups lies also in stabilizing the three-dimensional structure of proteins, thereby preserving their functional properties. Sulfhydryls play an important role in biochemistry as disulfide bonds connect amin ...
WHAT`S THE NEXT STEP?
... display less affinity for the CYP3A4 enzyme. The Phe must be maintained in order for the drug’s mechanism of action to proceed; that being, to bind to the virus’ protease and inhibit its function. However, by altering the position of the hydroxide, or by modifying the side-groups of the backbone, su ...
... display less affinity for the CYP3A4 enzyme. The Phe must be maintained in order for the drug’s mechanism of action to proceed; that being, to bind to the virus’ protease and inhibit its function. However, by altering the position of the hydroxide, or by modifying the side-groups of the backbone, su ...
appendix - iii
... 0.05). There were no serious clinical adverse events caused by the study drug in any of the groups. ...
... 0.05). There were no serious clinical adverse events caused by the study drug in any of the groups. ...
advances in pulmonary delivery of inhaled anti
... Anti-fungal treatment regimens for ABPA and aspergillus bronchitis commonly rely on oral triazoles, such as itraconazole and voriconazole, that inhibit fungal cytochrome P450 synthesis of ergosterol, a critical component of the fungal cell wall.20 ABPA is a more severe disease than aspergillus bronc ...
... Anti-fungal treatment regimens for ABPA and aspergillus bronchitis commonly rely on oral triazoles, such as itraconazole and voriconazole, that inhibit fungal cytochrome P450 synthesis of ergosterol, a critical component of the fungal cell wall.20 ABPA is a more severe disease than aspergillus bronc ...
New psychoactive substances
... They tend to binge use NPS, often using a range of substances, over a number of days. As such they are regularly at risk of acute toxicity and are vulnerable to other harms related to intoxication including risky sex and transmission of sexually transmitted infections. As they may have developed no ...
... They tend to binge use NPS, often using a range of substances, over a number of days. As such they are regularly at risk of acute toxicity and are vulnerable to other harms related to intoxication including risky sex and transmission of sexually transmitted infections. As they may have developed no ...
The Patented Medicines (Notice of Compliance) Regulations
... medicinal ingredient, whether chemical or biological in nature, when prepared or produced by the methods or processes of manufacture particularly described and claimed in the patent, or by their obvious chemical equivalents, and also includes a claim for different polymorphs of the medicinal ingredi ...
... medicinal ingredient, whether chemical or biological in nature, when prepared or produced by the methods or processes of manufacture particularly described and claimed in the patent, or by their obvious chemical equivalents, and also includes a claim for different polymorphs of the medicinal ingredi ...
Guideline on the Evaluation of the Pharmacokinetics of
... Presently, no well-established, adequate markers for hepatic function in terms of drug elimination capacity are available. The Child-Pugh classification The Child-Pugh classification is the most widely used and is one way of categorising hepatic function. However, it was not developed for the purpos ...
... Presently, no well-established, adequate markers for hepatic function in terms of drug elimination capacity are available. The Child-Pugh classification The Child-Pugh classification is the most widely used and is one way of categorising hepatic function. However, it was not developed for the purpos ...
Drug target for lymphatic filariasis
... several fruitful drug targets. Moreover, miRNAs are involved in various regulations and developmental process of nematodes. Genomics study can find a variety of genes which regulate or may take part in central role for miRNA processing. Several investigators have identified novel functions of miRNAs ...
... several fruitful drug targets. Moreover, miRNAs are involved in various regulations and developmental process of nematodes. Genomics study can find a variety of genes which regulate or may take part in central role for miRNA processing. Several investigators have identified novel functions of miRNAs ...
Pharmacognosy
Pharmacognosy is the study of medicinal drugs derived from plants or other natural sources. The American Society of Pharmacognosy defines pharmacognosy as ""the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources.""It is also defined as the study of crude drugs.