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unit 5 study guide (ch 12-13)
unit 5 study guide (ch 12-13)

... A) give the complementary DNA sequence: B) give the mRNA sequence (use the original DNA!): C) tRNA sequence (use the mRNA sequence above!): D) amino acid sequence (use the mRNA codons!): 15) If a mutation occurred in the above DNA strand, in which a “G” was inserted after the 5th nucleotide: A) what ...
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Replisome



The replisome is a complex molecular machine that carries out replication of DNA. The replisome first unwinds double stranded DNA into two single strands. For each of the resulting single strands, a new complementary sequence of DNA is synthesized. The net result is formation of two new double stranded DNA sequences that are exact copies of the original double stranded DNA sequence.In terms of structure, the replisome is composed of two replicative polymerase complexes, one of which synthesizes the leading strand, while the other synthesizes the lagging strand. The replisome is composed of a number of proteins including helicase, RFC, PCNA, gyrase/topoisomerase, SSB/RPA, primase, DNA polymerase I, RNAse H, and ligase.
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