Psychology in the 21st Century
... express these conflicting points of view (although Shakespeare had earlier used these exact words: In The Tempest, Prospero says, "A devil, a born devil, on whose nature/Nurture can never stick…"). Galton believed in Nature and that a characteristic he called “eminence” could be inherited. Eminent p ...
... express these conflicting points of view (although Shakespeare had earlier used these exact words: In The Tempest, Prospero says, "A devil, a born devil, on whose nature/Nurture can never stick…"). Galton believed in Nature and that a characteristic he called “eminence” could be inherited. Eminent p ...
Gene Regulation and Genetics
... decreases or increases in the activity of the genes affected. The changes in the placement of the methyl tags may be responsible for a variety of changes in cellular function that occur during aging. There is also evidence that abnormal placement of the methyl tags may contribute to the development ...
... decreases or increases in the activity of the genes affected. The changes in the placement of the methyl tags may be responsible for a variety of changes in cellular function that occur during aging. There is also evidence that abnormal placement of the methyl tags may contribute to the development ...
Position effect variegation in Drosophila: moving a gene near
... Darkly stained region of chromosome Highly compacted even during interphase Usually found in regions near centromere Constitutive heterochromatin remains condensed most of time in all cells (e.g., Y chromosomes in flies and ...
... Darkly stained region of chromosome Highly compacted even during interphase Usually found in regions near centromere Constitutive heterochromatin remains condensed most of time in all cells (e.g., Y chromosomes in flies and ...
The prefrontal cortex (PFC) is responsible for higher
... The prefrontal cortex (PFC) is responsible for higher-level cognition, such as personality expression and social behavior. The PFC has connections with the amygdala, locus coeruleus, ventral tegmental area, and hippocampus. The PFC, however, is particularly susceptible to stress. This research seeks ...
... The prefrontal cortex (PFC) is responsible for higher-level cognition, such as personality expression and social behavior. The PFC has connections with the amygdala, locus coeruleus, ventral tegmental area, and hippocampus. The PFC, however, is particularly susceptible to stress. This research seeks ...
Fellows seminar 9-19-2014
... Tarun (2012) identified 23 genes for which methylation collectively explained 70-87% of the variance in birth weight Gordon (2012) found methylation in 8 genes to be associated with birth weight after correction for multiple ...
... Tarun (2012) identified 23 genes for which methylation collectively explained 70-87% of the variance in birth weight Gordon (2012) found methylation in 8 genes to be associated with birth weight after correction for multiple ...
sTOrY - Katherine Pollard
... which regions have been evolving the fastest. This process has highlighted a region called HAR1, short for human accelerated region-1, which is 118 DNA base pairs long (Nature, vol 443, p 167). We do not yet know what HAR1 does, but we do know that it is switched on in the fetal brain between 7 and ...
... which regions have been evolving the fastest. This process has highlighted a region called HAR1, short for human accelerated region-1, which is 118 DNA base pairs long (Nature, vol 443, p 167). We do not yet know what HAR1 does, but we do know that it is switched on in the fetal brain between 7 and ...
ppt - Chair of Computational Biology
... genes are expressed (switched on) when the chromatin is open (active), and they are inactivated (switched off) when the chromatin is condensed (silent). ...
... genes are expressed (switched on) when the chromatin is open (active), and they are inactivated (switched off) when the chromatin is condensed (silent). ...
TemporalHeterogeneit..
... Epigenetics is the study of mitotically and/or meiotically heritable changes in gene function that cannot be explained by changes in DNA sequence. ...
... Epigenetics is the study of mitotically and/or meiotically heritable changes in gene function that cannot be explained by changes in DNA sequence. ...
DNA Structure
... being histone acetylation. – the attachment of acetyl groups to lysine amino acids in the N-terminal regions of each of the core molecules. These N termini form tails that protrude from the nucleosome core octamer and their acetylation reduces the affinity of the histones for DNA and possibly also r ...
... being histone acetylation. – the attachment of acetyl groups to lysine amino acids in the N-terminal regions of each of the core molecules. These N termini form tails that protrude from the nucleosome core octamer and their acetylation reduces the affinity of the histones for DNA and possibly also r ...
Natural selection and the function of genome imprinting:
... wide variety of organisms (Table 1) cannot be used as an argument that parental origin effects, per se, have been selected to serve some purpose because the generation of epigenetic differences between maternal and paternal genomes might be a consequence of sexual reproduction. However, we can infer ...
... wide variety of organisms (Table 1) cannot be used as an argument that parental origin effects, per se, have been selected to serve some purpose because the generation of epigenetic differences between maternal and paternal genomes might be a consequence of sexual reproduction. However, we can infer ...
Gene Mutation Link With HIV Resistance
... In nuclear transfer cloning, reprogramming is allotted precious little time—minutes to hours. When a micropipette injects a donor nucleus into a waiting egg, the donor’s genome retains its old, worn configuration. It knows only how to make other cells of its kind, whether skin, muscle, or something ...
... In nuclear transfer cloning, reprogramming is allotted precious little time—minutes to hours. When a micropipette injects a donor nucleus into a waiting egg, the donor’s genome retains its old, worn configuration. It knows only how to make other cells of its kind, whether skin, muscle, or something ...
Boulder 2014 Friday 9am NGM - Institute for Behavioral Genetics
... Heritability estimates are wrong Nonadditivity of gene effects – epistasis, GxE Epigenetics – including parent-of-origin effects Low power for common small effects Disease heterogeneity – lots of different diseases with the same phenotype ...
... Heritability estimates are wrong Nonadditivity of gene effects – epistasis, GxE Epigenetics – including parent-of-origin effects Low power for common small effects Disease heterogeneity – lots of different diseases with the same phenotype ...
REGULATION OF GENE EXPRESSION
... This phenomenon occurs in normal cell growth in some species as well as in abnormal cell growth such as in some cancerous conditions W In normal cell growth : (1) In the amphibian Xenopus laevis, rDNA gene number is amplified 2500 times during oogenesis to respond to great protein synthesis needs, t ...
... This phenomenon occurs in normal cell growth in some species as well as in abnormal cell growth such as in some cancerous conditions W In normal cell growth : (1) In the amphibian Xenopus laevis, rDNA gene number is amplified 2500 times during oogenesis to respond to great protein synthesis needs, t ...
Heredity and Environment
... • Hoerger, M. (2007, January 17). Heredity and Environment. Presented at a PSY 220 ...
... • Hoerger, M. (2007, January 17). Heredity and Environment. Presented at a PSY 220 ...
RNA polymerase
... Eukaryotic cells modify mRNA after transcription. Splicing of mRNA increases the number of different proteins an organism can produce. Gene expression is regulated by proteins that bind to specific base sequences in DNA. The environment of a cell and of an organism has an impact on gene expression. ...
... Eukaryotic cells modify mRNA after transcription. Splicing of mRNA increases the number of different proteins an organism can produce. Gene expression is regulated by proteins that bind to specific base sequences in DNA. The environment of a cell and of an organism has an impact on gene expression. ...
Presentation - people.vcu.edu
... Weng, Y.-I., Huang, T. H.-M., & Yan, P. S. (2009). Methylated DNA Immunoprecipitation and Microarray-Based Analysis: Detection of DNA Methylation in Breast Cancer Cell Lines. Methods in Molecular Biology (Clifton, N.J.), 590, 165–176. ...
... Weng, Y.-I., Huang, T. H.-M., & Yan, P. S. (2009). Methylated DNA Immunoprecipitation and Microarray-Based Analysis: Detection of DNA Methylation in Breast Cancer Cell Lines. Methods in Molecular Biology (Clifton, N.J.), 590, 165–176. ...
Hogart A, Leung KN, Wang NJ, Wu DJ, Driscoll J
... SNRPN, NDN, HBII85, and HBII52 and unchanged levels of maternally expressed UBE3A compared to controls. Paternal expression abnormalities in the female duplication sample were consistent with elevated DNA methylation of the 15q11–13 imprinting control region (ICR). Expression of non-imprinted 15q11– ...
... SNRPN, NDN, HBII85, and HBII52 and unchanged levels of maternally expressed UBE3A compared to controls. Paternal expression abnormalities in the female duplication sample were consistent with elevated DNA methylation of the 15q11–13 imprinting control region (ICR). Expression of non-imprinted 15q11– ...
Environmental and genetic interaction
... lower levels of psychopathology than those that posses the “vulnerable” allele In maltreated children: ...
... lower levels of psychopathology than those that posses the “vulnerable” allele In maltreated children: ...
组蛋白甲基化
... both strands of DNA. Most DNA methylations are found on cytosine on both strands of the CpG doublet. A hemi-methylated site is a palindromic sequence that is methylated on only one strand of DNA. Replication converts a fully methylated site to a ...
... both strands of DNA. Most DNA methylations are found on cytosine on both strands of the CpG doublet. A hemi-methylated site is a palindromic sequence that is methylated on only one strand of DNA. Replication converts a fully methylated site to a ...
Bridging the transgenerational gap with epigenetic memory
... RNAs, since the role of DNA methylation has been extensively reviewed elsewhere [16–21]. We mostly focus on instances of nongenetic inheritance that persist for several generations (but that are not permanent), because persistence over multiple generations reduces likelihood of confounding factors, ...
... RNAs, since the role of DNA methylation has been extensively reviewed elsewhere [16–21]. We mostly focus on instances of nongenetic inheritance that persist for several generations (but that are not permanent), because persistence over multiple generations reduces likelihood of confounding factors, ...
Imprinting
... – If X from father- better verbal and social skills than if X from mother – Conclude- Some imprinted genes on X escape inactivation only if from father ...
... – If X from father- better verbal and social skills than if X from mother – Conclude- Some imprinted genes on X escape inactivation only if from father ...
Chapter 4. The Epigenetics of Non
... not translated into proteins. Many are functional and are involved in the processing and regulation of other RNAs such as mRNA, tRNA, and rRNA. Processing-type ncRNAs include small nuclear RNAs (snRNAs) involved in splicing, small nucleolar RNAs (snoRNAs) that modify nucleotides in rRNAs and other R ...
... not translated into proteins. Many are functional and are involved in the processing and regulation of other RNAs such as mRNA, tRNA, and rRNA. Processing-type ncRNAs include small nuclear RNAs (snRNAs) involved in splicing, small nucleolar RNAs (snoRNAs) that modify nucleotides in rRNAs and other R ...
The Epigenetics of Non
... not translated into proteins. Many are functional and are involved in the processing and regulation of other RNAs such as mRNA, tRNA, and rRNA. Processing-type ncRNAs include small nuclear RNAs (snRNAs) involved in splicing, small nucleolar RNAs (snoRNAs) that modify nucleotides in rRNAs and other R ...
... not translated into proteins. Many are functional and are involved in the processing and regulation of other RNAs such as mRNA, tRNA, and rRNA. Processing-type ncRNAs include small nuclear RNAs (snRNAs) involved in splicing, small nucleolar RNAs (snoRNAs) that modify nucleotides in rRNAs and other R ...
Plant Comparative Genomics
... Overview: Our research is focused on understanding the underlying molecular evolutionary processes that contribute to phenotypic diversity, particularly those processes pertaining to genome structure and affecting gene expression. By combining the power of comparative genomics with bioinformatics, w ...
... Overview: Our research is focused on understanding the underlying molecular evolutionary processes that contribute to phenotypic diversity, particularly those processes pertaining to genome structure and affecting gene expression. By combining the power of comparative genomics with bioinformatics, w ...
Behavioral epigenetics
Behavioral epigenetics is the field of study examining the role of epigenetics in shaping animal (including human) behaviour. It is an experimental science that seeks to explain how nurture shapes nature, where nature refers to biological heredity and nurture refers to virtually everything that occurs during the life-span (e.g., social-experience, diet and nutrition, and exposure to toxins). Behavioral epigenetics attempts to provide a framework for understanding how the expression of genes is influenced by experiences and the environment to produce individual differences in behaviour, cognition personality, and mental health.Epigenetic gene regulation involves changes other than to the sequence of DNA and includes changes to histones (proteins around which DNA is wrapped) and DNA methylation. These epigenetic changes can influence the growth of neurons in the developing brain as well as modify activity of the neurons in the adult brain. Together, these epigenetic changes on neuron structure and function can have a marked influence on an organism's behavior.