The roles of iron in health and disease
... Iron is vital for almost all living organisms by participating in a wide variety of metabolic processes, including oxygen transport, DNA synthesis, and electron transport. However, iron concentrations in body tissues must be tightly regulated because excessive iron leads to tissue damage, as a resul ...
... Iron is vital for almost all living organisms by participating in a wide variety of metabolic processes, including oxygen transport, DNA synthesis, and electron transport. However, iron concentrations in body tissues must be tightly regulated because excessive iron leads to tissue damage, as a resul ...
Genes Involved in the Uptake and Catabolism of
... e St? recombinants were selected on glucose medium also containing methionine, and these were screened for any that had lost their ability to grow on gluconate. Strain BBI, which was unable to grow on gluconate, was thus obtained and was used for further biochemical and genetic studies. This strain ...
... e St? recombinants were selected on glucose medium also containing methionine, and these were screened for any that had lost their ability to grow on gluconate. Strain BBI, which was unable to grow on gluconate, was thus obtained and was used for further biochemical and genetic studies. This strain ...
Genes Involved in the Uptake and Catabolism of
... e St? recombinants were selected on glucose medium also containing methionine, and these were screened for any that had lost their ability to grow on gluconate. Strain BBI, which was unable to grow on gluconate, was thus obtained and was used for further biochemical and genetic studies. This strain ...
... e St? recombinants were selected on glucose medium also containing methionine, and these were screened for any that had lost their ability to grow on gluconate. Strain BBI, which was unable to grow on gluconate, was thus obtained and was used for further biochemical and genetic studies. This strain ...
PDF
... embryos mutant for ptc1 and ptc2, the otic vesicle is strongly medialised and ventralised as well as posteriorised, and has a stronger phenotype than that generated by shh mRNA injection (Hammond et al., 2003). Gene expression pattern changes in the otic vesicle prefigure the defects in ptc1–/–; lep ...
... embryos mutant for ptc1 and ptc2, the otic vesicle is strongly medialised and ventralised as well as posteriorised, and has a stronger phenotype than that generated by shh mRNA injection (Hammond et al., 2003). Gene expression pattern changes in the otic vesicle prefigure the defects in ptc1–/–; lep ...
Chapter 7 - Research Explorer
... cyanobacteria display an unexpected diversity in CO2 responses, because different strains combine their uptake systems for CO2 and bicarbonate in different ways. The genetic composition of cyanobacterial blooms may therefore shift. In particular, strains with lowaffinity uptake systems may benefit f ...
... cyanobacteria display an unexpected diversity in CO2 responses, because different strains combine their uptake systems for CO2 and bicarbonate in different ways. The genetic composition of cyanobacterial blooms may therefore shift. In particular, strains with lowaffinity uptake systems may benefit f ...
Ethylene Signal Transduction. Moving beyond
... robustness of models developed in plants such as Arabidopsis. Indeed, with the critical role of ethylene in mediating environmental responses, we would not expect that an annual rosette plant would behave like a perennial vine. In the end, it is only by elaborating the differences between species th ...
... robustness of models developed in plants such as Arabidopsis. Indeed, with the critical role of ethylene in mediating environmental responses, we would not expect that an annual rosette plant would behave like a perennial vine. In the end, it is only by elaborating the differences between species th ...
Phosphorus requirement of the sporophyte of Laminaria japonica
... ature and low phosphorus period from May to November. In the low water temperature and high phosphorus period, the sporophyte of L. japonica were considered to use mainly inorganic phosphorus because they comprised more than 50% of total available dissolved phosphorus. On the contrary, dissolved org ...
... ature and low phosphorus period from May to November. In the low water temperature and high phosphorus period, the sporophyte of L. japonica were considered to use mainly inorganic phosphorus because they comprised more than 50% of total available dissolved phosphorus. On the contrary, dissolved org ...
Sporulation in BhciZZus subtilis 168. Control of
... temperature with a solution of p-nitrophenyl phosphate (15mg/ml in I -0M-diethanolamineHCI buffer, pH 10.0).Colonies with low alkaline phosphatase activity remained white, while normal colonies immediately turned a bright yellow. The white colonies were picked, streaked on glucose-glutamate minimal ...
... temperature with a solution of p-nitrophenyl phosphate (15mg/ml in I -0M-diethanolamineHCI buffer, pH 10.0).Colonies with low alkaline phosphatase activity remained white, while normal colonies immediately turned a bright yellow. The white colonies were picked, streaked on glucose-glutamate minimal ...
hnRNP I is required to generate the Ca signal that
... Wenyan Mei1,2, Karen W. Lee3,*, Florence L. Marlow1, Andrew L. Miller3 and Mary C. Mullins1,† Egg activation is an important cellular event required to prevent polyspermy and initiate development of the zygote. Egg activation in all animals examined is elicited by a rise in free Ca2+ in the egg cyto ...
... Wenyan Mei1,2, Karen W. Lee3,*, Florence L. Marlow1, Andrew L. Miller3 and Mary C. Mullins1,† Egg activation is an important cellular event required to prevent polyspermy and initiate development of the zygote. Egg activation in all animals examined is elicited by a rise in free Ca2+ in the egg cyto ...
icsi sperm selection by ha binding
... sperm zona-binding site(s) is regulated by the remodelling of the plasma membrane during spermiogenesis. Mature spermatozoa may selectively bind to solid state HA. Spermatozoa bind head-first to HA with the acrosomal region. Spermatozoa with advanced levels of capacitaion or acrosome reaction ...
... sperm zona-binding site(s) is regulated by the remodelling of the plasma membrane during spermiogenesis. Mature spermatozoa may selectively bind to solid state HA. Spermatozoa bind head-first to HA with the acrosomal region. Spermatozoa with advanced levels of capacitaion or acrosome reaction ...
Surgical Sperm Retrieval
... an operating microscope a tiny cut is made into the epididymis and the fluid within is removed and examined to see if there are any sperm present. If sufficient sperm cells are found they can be frozen for subsequent use in a future IVF/ICSI cycle. 2. Percutaneous Epidydimal Sperm Aspiration (PESA) ...
... an operating microscope a tiny cut is made into the epididymis and the fluid within is removed and examined to see if there are any sperm present. If sufficient sperm cells are found they can be frozen for subsequent use in a future IVF/ICSI cycle. 2. Percutaneous Epidydimal Sperm Aspiration (PESA) ...
PDF - Hormones.gr
... Figure 2. The HPA axis and the glucocorticoid signaling pathway. Upon stimulation of the HPA axis by numerous external or internal stressful stimuli, neurons of the paraventricular nuclei located in the hypothalamus release CRH and AVP, which both increase the production and secretion of ACTH by the ...
... Figure 2. The HPA axis and the glucocorticoid signaling pathway. Upon stimulation of the HPA axis by numerous external or internal stressful stimuli, neurons of the paraventricular nuclei located in the hypothalamus release CRH and AVP, which both increase the production and secretion of ACTH by the ...
Full Text - The International Journal of Developmental Biology
... Sperm-egg interactions in GM animals 659 gene Hyal5 very close to PH-20 in the genome (Kim et al., 2005). The role of hyaluronidase in sperm-egg interaction will be concluded when we see the binding ability impaired sperm from Hyal5 knockout or PH-20 and Hyal5 double knockout mice. There are more f ...
... Sperm-egg interactions in GM animals 659 gene Hyal5 very close to PH-20 in the genome (Kim et al., 2005). The role of hyaluronidase in sperm-egg interaction will be concluded when we see the binding ability impaired sperm from Hyal5 knockout or PH-20 and Hyal5 double knockout mice. There are more f ...
Fatty Acid Transport Protein 4 (FATP4) Prevents Light
... In vitro retinoid isomerase assay. The assay mixtures contained 10 M atROL (or 15 M all-trans retinyl palmitate), 6% BSA, and 100 g of mouse RPE homogenates or 500 g of Sf9 cell homogenates in 20 mM HEPES buffer. When atRP was used as a substrate, 6 mM sodium cholate was added to the reaction mi ...
... In vitro retinoid isomerase assay. The assay mixtures contained 10 M atROL (or 15 M all-trans retinyl palmitate), 6% BSA, and 100 g of mouse RPE homogenates or 500 g of Sf9 cell homogenates in 20 mM HEPES buffer. When atRP was used as a substrate, 6 mM sodium cholate was added to the reaction mi ...
Case Report Ain`t No Sunshine When She`s Gone
... (5 mmol/day) was low, as is seen in hypoparathyroidism. However, the PTH level was increased (22.1 pmol/L), whereas 25(OH)-vitamin D was low (31 nmol/L). An Ellsworth-Howard test showed only a fivefold increase in urinary phosphate excretion after administration of synthetic PTH, supporting the diag ...
... (5 mmol/day) was low, as is seen in hypoparathyroidism. However, the PTH level was increased (22.1 pmol/L), whereas 25(OH)-vitamin D was low (31 nmol/L). An Ellsworth-Howard test showed only a fivefold increase in urinary phosphate excretion after administration of synthetic PTH, supporting the diag ...
+ Sev/RTK (lf)
... A cDNA clone encoding a novel, widely expressed protein (called growth factor receptor-bound protein 2 or GRB2) containing one src homology 2 (SH2) domain and two SH3 domains was isolated. Immunoblotting experiments indicate that GRB2 associates with tyrosinephosphorylated epidermal growth factor re ...
... A cDNA clone encoding a novel, widely expressed protein (called growth factor receptor-bound protein 2 or GRB2) containing one src homology 2 (SH2) domain and two SH3 domains was isolated. Immunoblotting experiments indicate that GRB2 associates with tyrosinephosphorylated epidermal growth factor re ...
What are enzymes?
... biochemical reaction which they are catalyzing. When the biochemical reaction is over, the enzyme is ready to effect the same reaction on another molecule again and again. Given the right conditions, the enzyme can go on and on for as long as needed. In some production processes, this lowers costs. ...
... biochemical reaction which they are catalyzing. When the biochemical reaction is over, the enzyme is ready to effect the same reaction on another molecule again and again. Given the right conditions, the enzyme can go on and on for as long as needed. In some production processes, this lowers costs. ...
lecture - Berkeley MCB
... "repressor" which blocks the synthesis of b-galactosidase, and the exogenous inducer displaces this repressor and restores enzyme synthesis. With the i- allele, present in an inactive form in the constitutives, the repressor is not formed, and b-galactosidase is synthesized, the exogenous inducer th ...
... "repressor" which blocks the synthesis of b-galactosidase, and the exogenous inducer displaces this repressor and restores enzyme synthesis. With the i- allele, present in an inactive form in the constitutives, the repressor is not formed, and b-galactosidase is synthesized, the exogenous inducer th ...
PART 16 - PTools.ir
... iodide symporter; Tg, thyroglobulin; TPO, thyroid peroxidase; TSH-R, thyroid-stimulating hormone receptor. ...
... iodide symporter; Tg, thyroglobulin; TPO, thyroid peroxidase; TSH-R, thyroid-stimulating hormone receptor. ...
G-PROTEIN-COUPLED RECEPTORS
... (Marinissen, 2001). Both the GTPbound α-subunit and the released βγ-dimer can modulate several cellular signaling pathways. These include, among others, stimulation or inhibition of adenylyl cyclases and activation of phospholipases, as well as regulation of potassium and calcium channel activity (H ...
... (Marinissen, 2001). Both the GTPbound α-subunit and the released βγ-dimer can modulate several cellular signaling pathways. These include, among others, stimulation or inhibition of adenylyl cyclases and activation of phospholipases, as well as regulation of potassium and calcium channel activity (H ...
Peptide signalling during the pollen tube journey and double
... classes: secreted peptides and non-secreted peptides. Secreted peptides can be further divided into two major classes: cysteine-rich peptides (CRPs) and non-CRPs (NCRPs). There are 432 NCRP genes annotated in the Arabidopsis genome including post-translationally modified small peptides and some prot ...
... classes: secreted peptides and non-secreted peptides. Secreted peptides can be further divided into two major classes: cysteine-rich peptides (CRPs) and non-CRPs (NCRPs). There are 432 NCRP genes annotated in the Arabidopsis genome including post-translationally modified small peptides and some prot ...
shows altered stratification and cell polarity
... significant change in the mRNA levels of these genes was detected (Fig. 2A and B). These genes were not further considered. Secondly, we considered a set of mammalian homologs of genes known to be downstream target of Drosophila dll. The latest included aristaless, barH1/barH2, bric-a-brac, dachshund ...
... significant change in the mRNA levels of these genes was detected (Fig. 2A and B). These genes were not further considered. Secondly, we considered a set of mammalian homologs of genes known to be downstream target of Drosophila dll. The latest included aristaless, barH1/barH2, bric-a-brac, dachshund ...
invited review
... Abstract: Vitamin D3 is one of the few natural compounds that has, via its metabolite 1␣,25-dihydroxyvitamin D3 (1,25(OH)2D3) and the transcription factor vitamin D receptor (VDR), a direct effect on gene regulation. For efficiently applying the therapeutic and disease-preventing potential of 1,25(OH ...
... Abstract: Vitamin D3 is one of the few natural compounds that has, via its metabolite 1␣,25-dihydroxyvitamin D3 (1,25(OH)2D3) and the transcription factor vitamin D receptor (VDR), a direct effect on gene regulation. For efficiently applying the therapeutic and disease-preventing potential of 1,25(OH ...
Splice variants of the SWR1-type nucleosome remodeling factor
... individual egg chambers. Oogenesis further runs through 14 stages of egg chamber development to produce a functional egg. It is not surprising that nucleosome remodeling factors have been found to be important for oogenesis given the widespread requirement for chromatin plasticity during development ...
... individual egg chambers. Oogenesis further runs through 14 stages of egg chamber development to produce a functional egg. It is not surprising that nucleosome remodeling factors have been found to be important for oogenesis given the widespread requirement for chromatin plasticity during development ...
Control of the proliferation versus meiotic development decision in
... where the distal proliferative zone increases in size over time, reflecting constitutive GLP-1 activity (Berry et al., 1997). In these animals, low GLD-1 levels extend much further proximally than in wild-type (Fig. 2). The maximum level, however, still coincides with the transition of germ cells fr ...
... where the distal proliferative zone increases in size over time, reflecting constitutive GLP-1 activity (Berry et al., 1997). In these animals, low GLD-1 levels extend much further proximally than in wild-type (Fig. 2). The maximum level, however, still coincides with the transition of germ cells fr ...
Nicotinic acid adenine dinucleotide phosphate
Nicotinic acid adenine dinucleotide phosphate, (NAADP), is a Ca2+-mobilizing second messenger synthesised in response to extracellular stimuli. Like its mechanistic cousins, IP3 and cyclic adenosine diphosphoribose (Cyclic ADP-ribose), NAADP binds to and opens Ca2+ channels on intracellular organelles, thereby increasing the intracellular Ca2+ concentration which, in turn, modulates sundry cellular processes (see Calcium signalling). Structurally, it is a dinucleotide that only differs from the house-keeping enzyme cofactor, NADP by a hydroxyl group (replacing the nicotinamide amino group) and yet this minor modification converts it into the most potent Ca2+-mobilizing second messenger yet described. NAADP acts across phyla from plants to man.