Predicting Protein Stability Changes upon Mutation Using Database
... it is a torsion potential taken individually; the respective correlation coef®cients reach 0.82 and 0.87. These results show that distance potentials, dominated by hydrophobic interactions, represent best the main interactions stabilizing the protein core, whereas torsion potentials, describing loca ...
... it is a torsion potential taken individually; the respective correlation coef®cients reach 0.82 and 0.87. These results show that distance potentials, dominated by hydrophobic interactions, represent best the main interactions stabilizing the protein core, whereas torsion potentials, describing loca ...
CHEMISTRY OF AQUATIC ORGANISMS AND THEIR UTILIZATION
... inner structure becomes clearer, although actual protein molecules have component atoms of amino acid packed in a narrow space of the molecule. Structural changes (fluctuations) might take place in the active state of a given protein, but cannot be determined by the present analytical methods. Some ...
... inner structure becomes clearer, although actual protein molecules have component atoms of amino acid packed in a narrow space of the molecule. Structural changes (fluctuations) might take place in the active state of a given protein, but cannot be determined by the present analytical methods. Some ...
Full Text
... [1986], who does use multiple overlapping amino acid groups based on known properties. However, his groups are based on a single Venn diagram of amino acid relationships. Furthermore, the amino acid groups at each position must cover the entire training set, so an incoherent sequence can easily make ...
... [1986], who does use multiple overlapping amino acid groups based on known properties. However, his groups are based on a single Venn diagram of amino acid relationships. Furthermore, the amino acid groups at each position must cover the entire training set, so an incoherent sequence can easily make ...
Lo, Frederick: Three Recently Developed Algorithms for Aligning Distantly Related Proteins
... valid substitution, a low value in the similarity matrix apparently indicates high similarity between residues. The iterative elimination algorithm begins by building a similarity matrix with the selected alignment algorithm. The best alignment (lowest sum) is determined by traversing the similarity ...
... valid substitution, a low value in the similarity matrix apparently indicates high similarity between residues. The iterative elimination algorithm begins by building a similarity matrix with the selected alignment algorithm. The best alignment (lowest sum) is determined by traversing the similarity ...
Bis-Triazinyl-Pyridines for selective extraction of americium(III
... However, trivalent actinides proved to form more stable complexes than lanthanides with molecules such as terpyridines or 2,6-bis([1,2,4]-triazin-3-yl)pyridines (BTPs)7. It is likely that the smaller steric demands of the [1,2,4]-triazin-3-yl ring by comparison with the 2pyridinyl ring, which allows ...
... However, trivalent actinides proved to form more stable complexes than lanthanides with molecules such as terpyridines or 2,6-bis([1,2,4]-triazin-3-yl)pyridines (BTPs)7. It is likely that the smaller steric demands of the [1,2,4]-triazin-3-yl ring by comparison with the 2pyridinyl ring, which allows ...
... Asp25 – activates main chain atoms are His – activated Ser. H2O as nucleophil. responsible for Asp – stabilizes pos charge on his H2O attacks peptide desolvation of ion so bond. Second Asp that it can pass provides proton for through the membrane. new amino terminus. 2nd Asp interacts Large non-pola ...
Mole-Volume Conversion Assignment
... Yesterday’s calculations we found out that when we use 50mL of 5% acetic acid solutions, we require 3.5g of sodium bicarbonate to completely react. Trial 1: use 1.0g of NaHCO3 and 50mL CH3COOH: extra vinegar left over: NaHCO3 all used Trial 2: use 2.0g of NaHCO3 and 50mL CH3COOH: extra vinegar left ...
... Yesterday’s calculations we found out that when we use 50mL of 5% acetic acid solutions, we require 3.5g of sodium bicarbonate to completely react. Trial 1: use 1.0g of NaHCO3 and 50mL CH3COOH: extra vinegar left over: NaHCO3 all used Trial 2: use 2.0g of NaHCO3 and 50mL CH3COOH: extra vinegar left ...
Inherited Propionyl
... 108 cells but her cells produced only 0.005 /Amoles "CO2/3 hr per 108 cells, although they oxidized methylmalonate-"C and succinate-1,4-"C normally. Thus, her fibroblasts expressed the same block in propionate oxidation as did her uncultured leukocytes (4). Propionate oxidation by her father's leuko ...
... 108 cells but her cells produced only 0.005 /Amoles "CO2/3 hr per 108 cells, although they oxidized methylmalonate-"C and succinate-1,4-"C normally. Thus, her fibroblasts expressed the same block in propionate oxidation as did her uncultured leukocytes (4). Propionate oxidation by her father's leuko ...
Oxidation of Fatty Acids Is the Source of Increased
... Proximal tubular cells (.90% of the kidney cortex) engage in active uptake and transepithelial transport of glucose, but only a small amount of glucose, if any, is used for ATP production (14). Moreover, diabetes causes a decrease in kidney glucose oxidation due to the inhibition of pyruvate dehydro ...
... Proximal tubular cells (.90% of the kidney cortex) engage in active uptake and transepithelial transport of glucose, but only a small amount of glucose, if any, is used for ATP production (14). Moreover, diabetes causes a decrease in kidney glucose oxidation due to the inhibition of pyruvate dehydro ...
Membranes for H2 Generation from Nuclear Powered
... power plants are being explored. The process being developed is the thermochemical production of Hydrogen. The Sulfur-Iodide (SI) cycle was deemed to be one of the most promising cycles to explore. The first step of the SI cycle involves the decomposition of H2SO4 into O2, SO2, and H2O at temperatur ...
... power plants are being explored. The process being developed is the thermochemical production of Hydrogen. The Sulfur-Iodide (SI) cycle was deemed to be one of the most promising cycles to explore. The first step of the SI cycle involves the decomposition of H2SO4 into O2, SO2, and H2O at temperatur ...
Chapter 1 The Foundations of Biochemistry
... Ans: Living organisms (1) are chemically complex and highly organized; (2) extract, transform, and use energy from their environment; (3) have the capacity to precisely self-replicate and self-assemble; (4) exploit a chemical interplay with their environment; (5) possess programmatically defined fun ...
... Ans: Living organisms (1) are chemically complex and highly organized; (2) extract, transform, and use energy from their environment; (3) have the capacity to precisely self-replicate and self-assemble; (4) exploit a chemical interplay with their environment; (5) possess programmatically defined fun ...
Bioinformatics Tools Review ()
... the sequence above. Click on the link gi|1498054|gb|U64437.1|ZMU64437 (Zea mays novel protein mRNA, complete cds) to see the nucleotide sequence file. The sequence file is in Genbank format. Note that the accession number is U64437 and this sequence is an mRNA sequence. The nucleotide sequence U644 ...
... the sequence above. Click on the link gi|1498054|gb|U64437.1|ZMU64437 (Zea mays novel protein mRNA, complete cds) to see the nucleotide sequence file. The sequence file is in Genbank format. Note that the accession number is U64437 and this sequence is an mRNA sequence. The nucleotide sequence U644 ...
Database searching with DNA and protein sequences
... This review of sequence database searching aims to set out current practice in the area, in order to give practical guidelines to the experimental biologist. It describes the basic principles behind the programs and enumerates the range of databases available in the public domain. Of these, the most ...
... This review of sequence database searching aims to set out current practice in the area, in order to give practical guidelines to the experimental biologist. It describes the basic principles behind the programs and enumerates the range of databases available in the public domain. Of these, the most ...
Mechanistic Details of the Oscillatory Belousov
... HBr0, and CHOH(COOH), as this is analogous to reaction 13 between Ce(ll1) and BrO,'. Other support for MA' control comes from Forsterling et aI.,l5 who found that in 3 M H2SO4I6and at very high [MA],/[BrO<], the potential of a Br--selective electrode oscillates in a range characteristic of HOBr rath ...
... HBr0, and CHOH(COOH), as this is analogous to reaction 13 between Ce(ll1) and BrO,'. Other support for MA' control comes from Forsterling et aI.,l5 who found that in 3 M H2SO4I6and at very high [MA],/[BrO<], the potential of a Br--selective electrode oscillates in a range characteristic of HOBr rath ...
Source–Sink Relationships
... degraded and the products of starch breakdown used for sucrose synthesis and export. Sufficient assimilate is stored in the leaves during the day to provide a constant supply of sucrose in the subsequent night, thus avoiding large diurnal fluctuations between supply from the source leaves. Sugars and a ...
... degraded and the products of starch breakdown used for sucrose synthesis and export. Sufficient assimilate is stored in the leaves during the day to provide a constant supply of sucrose in the subsequent night, thus avoiding large diurnal fluctuations between supply from the source leaves. Sugars and a ...
Molecular structure–reactivity relationships for the oxidation of sulfur
... To fully understand the molecular structure– reactivity relationships for the oxidation of sulfur dioxide over supported metal oxide catalysts a detailed knowledge of the molecular structures of the surface metal oxide species is required. Several studies have shown that Raman spectroscopy can readi ...
... To fully understand the molecular structure– reactivity relationships for the oxidation of sulfur dioxide over supported metal oxide catalysts a detailed knowledge of the molecular structures of the surface metal oxide species is required. Several studies have shown that Raman spectroscopy can readi ...
Flux distributions in anaerobic, glucose-limited
... Lutsdorf & Megnet (1968) ; von Jagow & Klingenberg ...
... Lutsdorf & Megnet (1968) ; von Jagow & Klingenberg ...
Amino acid profile of organically grown alternative agricultural
... Fig. 2. Amounts of nonessential amino acids in pumpkin pulp, g kg -1 dry matter. According to the literature the largest amounts of essential and nonessentials amino acids were in pumpkin flesh fertilized with complex fertilizers – 0.24 g kg-1 of essentials and 1.02 g kg-1 of nonessentials compared ...
... Fig. 2. Amounts of nonessential amino acids in pumpkin pulp, g kg -1 dry matter. According to the literature the largest amounts of essential and nonessentials amino acids were in pumpkin flesh fertilized with complex fertilizers – 0.24 g kg-1 of essentials and 1.02 g kg-1 of nonessentials compared ...
Publication: Amino acid profile of organically grown alternative
... Fig. 2. Amounts of nonessential amino acids in pumpkin pulp, g kg -1 dry matter. According to the literature the largest amounts of essential and nonessentials amino acids were in pumpkin flesh fertilized with complex fertilizers – 0.24 g kg-1 of essentials and 1.02 g kg-1 of nonessentials compared ...
... Fig. 2. Amounts of nonessential amino acids in pumpkin pulp, g kg -1 dry matter. According to the literature the largest amounts of essential and nonessentials amino acids were in pumpkin flesh fertilized with complex fertilizers – 0.24 g kg-1 of essentials and 1.02 g kg-1 of nonessentials compared ...
Mitochondrial protein acetylation regulates metabolism
... fractions were metabolic enzymes. Lysine acetylation was also identified on the mitochondrial DNA-encoded ATP synthase Fo subunit 8, implying that proteins can become acetylated within mitochondria. The acetylation status of several proteins is regulated by a large family of NAD+-dependent protein d ...
... fractions were metabolic enzymes. Lysine acetylation was also identified on the mitochondrial DNA-encoded ATP synthase Fo subunit 8, implying that proteins can become acetylated within mitochondria. The acetylation status of several proteins is regulated by a large family of NAD+-dependent protein d ...
Lecture 12 - Stoichiometry Lecture 12
... Many reactions occur in sequences. • This is particularly the case in biochemistry. • Such sequence of reactions are called pathways. The chemical equations can be added together to get an overall or net equation for the pathway. • For this to work, at least one of the products for a reaction in the ...
... Many reactions occur in sequences. • This is particularly the case in biochemistry. • Such sequence of reactions are called pathways. The chemical equations can be added together to get an overall or net equation for the pathway. • For this to work, at least one of the products for a reaction in the ...
Mitochondrial metabolite transport
... ADP and phosphate (Pi) for oxidative phosphorylation, substrates of the tricarboxylic acid cycle, fatty acid oxidation, mitochondrial replication and repair of DNA, mitochondrial RNA and protein synthesis, and amino acid degradation, coproporphyrinogen III and iron for haem biosynthesis, group donor ...
... ADP and phosphate (Pi) for oxidative phosphorylation, substrates of the tricarboxylic acid cycle, fatty acid oxidation, mitochondrial replication and repair of DNA, mitochondrial RNA and protein synthesis, and amino acid degradation, coproporphyrinogen III and iron for haem biosynthesis, group donor ...
Indole Alkaloids 1- Ergot Alkaloids - Home
... Members related to lysergic acid (e.g. ergotamine and ergometrine) are levorotatory, more active and designated by suffix “ine”. Members related to isolysergic acid (e.g. ergotaminine and ergometrinine), are dextrorotatory, less active and designated by ...
... Members related to lysergic acid (e.g. ergotamine and ergometrine) are levorotatory, more active and designated by suffix “ine”. Members related to isolysergic acid (e.g. ergotaminine and ergometrinine), are dextrorotatory, less active and designated by ...
Metalloprotein
Metalloprotein is a generic term for a protein that contains a metal ion cofactor. A large number of all proteins are part of this category.