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Prediction of DNA-binding residues in proteins from amino acid
Prediction of DNA-binding residues in proteins from amino acid

... in many fields for data classification. However, it is definitely time consuming to find the appropriate kernel function and optimal-free parameters of an SVM for very large training datasets. So it is significant to find a new algorithm that is fast and robust for different parameter values. (iii) ...
gene - Mrs. GM Biology 300
gene - Mrs. GM Biology 300

... color, height, skin color ...
When the individual organism develops from a fertilized egg, the
When the individual organism develops from a fertilized egg, the

... X chroniosomes that makes a fly female; if there is only one X, the fly will be male. Thc ring X chromosome has the property that it may get lost during nuclear division in the developing egg, so that some tissues retain only one X chromosome while others have both. Such a mosaic fly is a system in ...
Powerpoint summary
Powerpoint summary

... Biotech Time Line Humans domesticate crops and livestock ...
Insights into three whole-genome duplications gleaned
Insights into three whole-genome duplications gleaned

... after they diverged from P. caudatum, as there were up to four co-orthologs in each P. aurelia species for each P. caudatum protein. We counted a BLAST match as a RBH if a P. caudatum protein was the best hit for an aurelia protein and if that P. aurelia protein was also among the top 4 best hits fo ...
spp. DNA for Differentiation of Orpinomyces D1/D2 Domain of Large
spp. DNA for Differentiation of Orpinomyces D1/D2 Domain of Large

... multicopy LSU gives a possibility to design universal primers that can be easily amplified and has been shown to possess less intraindividual polymorphism (20). Moreover, this region has also been used for genus-level differentiation in anaerobic fungi (5) and species-level differentiation in yeasts ...
Divergent Evolution and Evolution by the Birth-and
Divergent Evolution and Evolution by the Birth-and

... for our study of long-term evolution was 57, and they are listed in table 1. We used the germ-line sequences whenever possible, to avoid the effect of somatic mutation ( Tonegawa 1983 ) . In a few species, however, we used cDNA, because germ-line genes were not available and sequence divergences wer ...
Water Soluble Vitamins 2
Water Soluble Vitamins 2

... elongation of a fatty acid chain Addition of CO2 to pyruvate to yield oxaloacetate Breaks down leucine Allows 3 essential amino acids to be oxidized for energy ...
Mutation, repair, and recombination
Mutation, repair, and recombination

... Question Which of the following statements is correct about the bases in DNA under normal circumstances: • Adenine should pair with thymine. • The bonds holding guanine and cytosine together are stronger than the bonds holding adenine and thymine together. • A purine always binds to a pyrimidine ...
Over-expression of a putative poplar glycosyltransferase gene
Over-expression of a putative poplar glycosyltransferase gene

... secondary metabolite-glycosylating enzymes was the largest and most diverse gene family identified, and much larger in poplar than in Arabidopsis, perhaps due to additional specialized functions in processes such as wood formation, dormancy, and longevity. The functions of several individual poplar ...
Practical exon and gene quantification in R
Practical exon and gene quantification in R

... The resulting bam variable is a list with the same number of entries as there are exons. Each entry is another list with what entries. In these entries, one element is present for each read mapped to that particular entry. To obtain the counts per exon, the following code is used: > counts <- lapply ...
Alzheimer's and the Ethical Issues of Genetic Testing
Alzheimer's and the Ethical Issues of Genetic Testing

... that people could become depressed or even dangerous if they find out they have an incurable disease. But the idea of genetic counseling, which I will introduce later, could help alleviate this potential societal harm. Another issue broached by the panel is the potential for discrimination, primaril ...
The distribution of DNA translocation times in solid
The distribution of DNA translocation times in solid

InterMine: extensive web services for modern
InterMine: extensive web services for modern

... as metadata (such as the data model) and specialized resources (such as DNA sequence export, region search and enrichment statistics). The web services enable users to automate data-based workflows or access data directly without using the InterMine web application. In addition, the presence of a co ...
Principles of transcriptional control in the metabolic
Principles of transcriptional control in the metabolic

... buffering the metabolic balance against genshown for comparison. Importantly, only genes coding for enzymes were used in the random control. (b) Genes of the glycolysis pathway (according to the KEGG database) were clustered and ordered etic mutations and for amplifying metabolic based on the correl ...
Slide 1 - Eweb.furman.edu
Slide 1 - Eweb.furman.edu

... A. Cell Structure/Function Review B. Chromosomal Terminology 1. chromatin: indistinguishable, diffuse chromosomes 2. chromosome: condensed strand of chromatin 3. “Ploidy” refers to the “information content” in the cell… how many ‘sets’ of chromosomes are there? - In eukaryotes, gametes and spores ar ...
Brooker Chapter 15
Brooker Chapter 15

... It is much more likely to cleave DNA in an open conformation than in a closed conformation ...


... 2011), requiring—similar to the ‘‘frequency approach’’—that favorable genes have at least two high-scoring reagents. Alternatively, RNAi Gene Enrichment Ranking (RIGER) ranks all the reagents by their differential effects and generates a gene-level score for each gene based on the rank distribution ...
Cell Reproduction
Cell Reproduction

... fists with overlapping fingers. Those with Edward's syndrome also have heart defects, and other organ malformations such that most systems of the body are affected. The survival rate for Edward's Syndrome is still incredibly low. Only 5 - 10% of liveborn infants will survive their first year of life ...
Main Title Slide — Always use Title Case on
Main Title Slide — Always use Title Case on

... of pretreatment peripheral blood and/or bone marrow samples. – Leukemia specimens with low cell counts are much less likely to be included for further genetic analyses. Exclusion of patients with incomplete data from the analyses is not recommended as it can lead to reduced statistical power, select ...
Addition of the keto functional group to the genetic
Addition of the keto functional group to the genetic

... Asp-158, Ile-159, and Leu-162) in the active site of M. jannaschii TyrRS were randomly mutated by PCR to generate a library 1.6 ⫻ 109 in size (4). This TyrRS mutant library was first passed through a positive selection in the presence of 1 mM p-acetylL-phenylalanine, which is based on the suppressio ...
EF-Tu PROTEIN DOMAINS
EF-Tu PROTEIN DOMAINS

... composed of three distinct domains, they can also serve as suitable models for the understanding of domain organization in proteins. One of the main research projects of the Department of Gene Expression at the Institute of Molecular Genetics AS CR, where I did my PhD studies, was the study of the p ...
Gene Section P53 (Protein 53 kDa) Atlas of Genetics and Cytogenetics
Gene Section P53 (Protein 53 kDa) Atlas of Genetics and Cytogenetics

... P53 gene alterations have been found in: - 20-30% of blast crisis CML (mostly in the myeloid type), often associated with i(17q); in - 5% of MDS cases and 15% of ANLL often with a visible del(17p); in - 2% of ALL (but with high variations according to the ALL type, reaching 50% of L3 ALL (and Burkit ...
Scientific Advisory Board
Scientific Advisory Board

... Each spiraling strand, comprised of a sugar-phosphate backbone and attached bases, is connected to a complementary strand by non-covalent hydrogen bonding between paired bases. The bases are adenine (A), thymine (T), cytosine (C) and guanine (G). ...
Experimentally testing the hypothesis of a limited amino acid
Experimentally testing the hypothesis of a limited amino acid

... a number of theories have been proposed. Crick proposed the frozen accident theory [1] in which he suggested two things; i) The code is universal because, at the present time, any change would be lethal, or at least very strongly selected against; and ii) The shape of the genetic code table was enti ...
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Artificial gene synthesis

Artificial gene synthesis is a method in synthetic biology that is used to create artificial genes in the laboratory. Currently based on solid-phase DNA synthesis, it differs from molecular cloning and polymerase chain reaction (PCR) in that the user does not have to begin with preexisting DNA sequences. Therefore, it is possible to make a completely synthetic double-stranded DNA molecule with no apparent limits on either nucleotide sequence or size. The method has been used to generate functional bacterial or yeast chromosomes containing approximately one million base pairs. Recent research also suggests the possibility of creating novel nucleobase pairs in addition to the two base pairs in nature, which could greatly expand the possibility of expanding the genetic code.Synthesis of the first complete gene, a yeast tRNA, was demonstrated by Har Gobind Khorana and coworkers in 1972. Synthesis of the first peptide- and protein-coding genes was performed in the laboratories of Herbert Boyer and Alexander Markham, respectively.Commercial gene synthesis services are now available from numerous companies worldwide, some of which have built their business model around this task. Current gene synthesis approaches are most often based on a combination of organic chemistry and molecular biological techniques and entire genes may be synthesized ""de novo"", without the need for precursor template DNA. Gene synthesis has become an important tool in many fields of recombinant DNA technology including heterologous gene expression, vaccine development, gene therapy and molecular engineering. The synthesis of nucleic acid sequences is often more economical than classical cloning and mutagenesis procedures.
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