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Free sample of
Free sample of

... 1. The nucleus _________, which is essential for function and survival of the cell. A) is the site of protein synthesis B) contains the genetic code C) transforms cellular energy D) initiates aerobic metabolism 2. Although energy is not made in mitochondria, they are known as the “power plants” of t ...
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BC 367 Biochemistry of the Cell I

... Compartmentalization allows control, particularly of opposing pathways. Pathways are controlled at a few key steps, usually the irreversible ones. ...
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Concept 11.2 Reception: A signaling molecule binds to a receptor
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... -Intracellular receptor proteins are found in the cytoplasm or nucleus of target cells. -Signaling molecules, a.k.a. chemical messengers can permeate through the membrane to reach these receptors Signaling molecules are hydrophobic or small enough to cross the ...
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... shed light on this process. It is regulated by receptor proteins located at the surface of specific cells that form a layer around the future break point. When it is time to shed an organ, a small hormone binds to this membrane receptor and, together with a helper protein, the abscission process is ...
P-glycoprotein Activation Monitored via ATP Hydrolysis and ATP
P-glycoprotein Activation Monitored via ATP Hydrolysis and ATP

... We investigated the relationship between the rate of ATP hydrolysis and ATP synthesis upon P-glycoprotein activation for several structurally different drugs, including local anaesthetics, cyclic peptides, and cytotoxic drugs. ATP hydrolysis was assessed by spectroscopically monitoring the release o ...
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... gland, IGF-II C-peptide causes proliferation of steroidogenic cells at 24 h. Therefore, the reduced levels of StAR protein are not a limiting factor of steroidogenesis for aldosterone producing cells. In conclusion, in addition to its direct effect on aldosterone production, a possible indirect effe ...
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SI Practice Exam / Review Sheet

Pathway Architect
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... the understanding of biological results. The software maps metabolites, proteins, and genes onto curated pathways, graphically projecting data onto pathway nodes or edges for interactive user analysis. Researchers can specify search criteria for particular organisms and browse a table of pathway res ...
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... cytometry allows for the multi-parametric analysis of cell and tissue lysates. The addition of activation state-specific (eg. phospho-specific) antibodies extends this method to the analysis of cell signaling in cell lines and patient samples. In this poster we describe the use of bead-based flow cy ...
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CHEM-643 Intermediary Metabolism Checklist for final group assignment on:
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... Conclusions that are supported by well-analyzed data and associated discussion Conclusions that are supported by multiple tests Exceptional elements that show depth of investigation, understanding, and presentation. ...
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... Insulin promotes glucose uptake into cells such as skeletal muscle cells, hence lowering glucose level in blood. Here we see the cross-talk between receptor and transporter. Insulin receptor failure causes type II diabetes. ...
Previously in Cell Bio
Previously in Cell Bio

... gains access to cytosol how can the information be transmitted? Extracellular domain ...
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Biochemical cascade

A biochemical cascade (or a signaling pathway) is a series of chemical reactions which are initiated by a stimulus (first messenger) acting on a receptor that is transduced to the cell interior through second messengers (which amplify the initial signal) and ultimately to effector molecules, resulting in a cell response to the initial stimulus. At each step of the signaling cascade, various controlling factors are involved to regulate cellular actions, responding effectively to cues about their changing internal and external environments.
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