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Inborn Errors of Metabolism
Inborn Errors of Metabolism

... – Phenylalanine build up causes brain damage. ...
Exam #2 Review
Exam #2 Review

... A. Catabolism = Harvesting energy released when a high-energy food molecule is BROKEN DOWN (oxidized, degraded). Glycolysis and the TCA cycle are basically catabolic pathways. However, because many of the intermediates formed in these pathways can serve as precursor metabolites, this gives these pat ...
Stem Cell Line Glossary Adult stem cells: Also known as somatic
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... Bringing a product or technology to market or making it commercially viable. Culture plate: A flat, transparent dish capable of holding some sort of liquid (medium) on which cells are grown. Differentiation: The ability of a cell to change from one type to another. A stem cell can differentiate into ...
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... its glycocalyx; therefore, the glycocalyx provides a very specific biological marker for cell recognition • Essentially I.D. tags for the cell to cell recognition ...
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... blood cells did not show any surface reactivity, hemopoietic cell lines K562, U937 and Daudi cells showed distinct cell staining (Fig. 2E). The epithelial cell line SCC also showed surface staining (Fig. 2E, d). The frequency of cells staining for these cell lines was low, varied with cell lines, an ...
EXPLORING PROTEIN STRUCTURE
EXPLORING PROTEIN STRUCTURE

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Activators - U of M wiki
Activators - U of M wiki

...  C5 is cleaved by either the Classical Pathway C5 convertase (C4b2aC3b) or by the Alternative Pathway C5 convertase (C3bBbC3b) into 2 fragments: C5a and C5b.  Cleavage of C5 is the last enzymatic step  C5b binds to a target and then interacts with C6, C7, C8 and C9 to form the Membrane Attack Com ...
Cell Biology Overview
Cell Biology Overview

... nucleus, cell wall, ribosomes, mitochondria, chloroplasts, endoplasmic reticulum, Golgi apparatus, vacuoles. (1a, 1e, 1f, 1g, 1j) Key Elements: 1. Describe the structure and function of the cell membrane. 2. Describe the role of the cell membrane in active and passive transport. 3. Describe the stru ...
Protein Biosynthesis
Protein Biosynthesis

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Principles of Metabolism
Principles of Metabolism

... • Maxwell’s Demon – a simple example • ATP and other phosphorylated molecules are frequently information carriers as well as energy carriers – for example, there is a large category of G-proteins (GTP-binding proteins) that serve as intracellular signals, and phosphorylating a protein is a universal ...
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1. The graph shows the relative levels of Cdk1 and cyclin B

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The Cell Membrane

... and their non-polar, hydrophobic fatty acid tails facing each other in the middle of the bilayer. This hydrophobic layer acts as a barrier to all but the smallest molecules, effectively isolating the two sides of the membrane. Different kinds of membranes can contain phospholipids with different fat ...
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Catecholamines (dopamine, norepinephrine, epinephrine)

... 1. Enzyme can metabolize both intra- or extracellularly 2. Requires Mg2+ and substrate of S-adenosylmethionine ...
View/Open - Oregon State University
View/Open - Oregon State University

... direction of the reaction is towards producing ethanol. Animals also have an alcohol dehydrogenase, but they use it for the reverse direction to break down ethanol. The product of the reverse reaction is acetaldehyde and may be responsible for hangovers. 9. Glycolysis is regulated by three enzymes - ...
Molecular Principles of Bioactive Systems
Molecular Principles of Bioactive Systems

... IV. Course objectives The ability to understand the relationship structure - function (reactivity, affinity, etc.), the main classes of biopolymers (proteins, nucleic acids, lipids, polysaccharides) that provides the morphological structure and functions of cells and supra-cellular structures of ani ...
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... consistent with a PDE role for the YoaD protein (inhibition of cellulose biosynthesis), but…. Why would both postitive (csgBA, adrA) and negative (yoaD) factors for bacterial cell aggregation be regulated by the same mechanism? ...
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... Dopamine Receptors • There are five types of dopamine receptors.D1,D2,D3,D4,D5. • We can catogorize dopamine receptors in two two main subtypes: • D1 like receptor family: the Gs protein is involved and adenylyl cyclase would be activated. The action of the enzyme causes the conversion of adenosine ...
CELLular biology
CELLular biology

... o Cytoskeleton – a protein network in the cytoplasm that gives cells structural support o Lysosomes – a membrane-bound organelle responsible for the breakdown of cellular waste o Ribosomes – responsible for protein production o Chloroplast – specialized organelle in plants responsible for Mitochondr ...
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Lecture 8 - People Server at UNCW

... same number of positive and negative charges in cell. HCO3- / Cl- exchanger When HCO3- moves out, Cl- moves in. ...
Gene Section PTPN6 (protein tyrosine phosphatase, non- receptor type 6)
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... PTPN6 plays a peculiar role in the maturation and functional differentiation of lymphoid and myeloid cells as underlined by the aberrant proliferation and impaired hematopoiesis in the "motheaten" (me) mice that display defects in the Shp-1 gene expression. The role of PTPN6 in hematopoiesis has bee ...
Solutions to 7
Solutions to 7

... In variant 2, one of the 2 hydrogen bonds remains, as does the hydrophobic pocket, and given the information this is enough to allow binding. In variant 3, both hydrogen bonds have been lost, and this disrupts the binding. ii) variant 5 will bind Minoxidil but variant 4 will not bind Minoxidil. In v ...
PATHWAYS THAT HARVEST CHEMICAL ENERGY CHAPTER 9
PATHWAYS THAT HARVEST CHEMICAL ENERGY CHAPTER 9

... • Acetyl CoA is the starting point of the eight –reaction citric acid cycle: • Inputs: acetyl CoA, water and electron carriers NAD+, FAD, and GDP • Energy released is captured by ADP and electron carriers NAD+, FAD, and GDP • Outputs: CO2, reduced electron carriers, and GTP, which converts ADP to AT ...
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Biochemical cascade

A biochemical cascade (or a signaling pathway) is a series of chemical reactions which are initiated by a stimulus (first messenger) acting on a receptor that is transduced to the cell interior through second messengers (which amplify the initial signal) and ultimately to effector molecules, resulting in a cell response to the initial stimulus. At each step of the signaling cascade, various controlling factors are involved to regulate cellular actions, responding effectively to cues about their changing internal and external environments.
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