Document
... •Common patterns found in different proteins •Typically have similar function •Caused by evolution (gene recombination / duplication) Ricin B chain • Two domains • Each domain is a trefoil ...
... •Common patterns found in different proteins •Typically have similar function •Caused by evolution (gene recombination / duplication) Ricin B chain • Two domains • Each domain is a trefoil ...
DV axis HT12
... Share homology with trypsin-like family of extracellular serine proteases. Typically secreted as inactive zymogen forms that are activated by proteolytic cleavage between N and C terminal domains. Pre-activated forms of Snake and Easter lacking N-terminal sequences have been used to order Gastr ...
... Share homology with trypsin-like family of extracellular serine proteases. Typically secreted as inactive zymogen forms that are activated by proteolytic cleavage between N and C terminal domains. Pre-activated forms of Snake and Easter lacking N-terminal sequences have been used to order Gastr ...
Protein Structure and Enzyme Function
... combinations of these 20 amino acids “letters.” For example, the word “CAT” is spelled “C,” “A,” “T” and it cannot be spelled any other way. Rearrange the letters and you get TAC or ACT, neither of which describe the fluffy, whiskered critter you’re trying to describe. The letters of the alphabet ar ...
... combinations of these 20 amino acids “letters.” For example, the word “CAT” is spelled “C,” “A,” “T” and it cannot be spelled any other way. Rearrange the letters and you get TAC or ACT, neither of which describe the fluffy, whiskered critter you’re trying to describe. The letters of the alphabet ar ...
ppt
... Passive transport: molecule movement across membrane determined by concentration and electrochemical gradients. ...
... Passive transport: molecule movement across membrane determined by concentration and electrochemical gradients. ...
Protein
... – Denaturation breaks the hydrogen bonds that create the twists and turns of a protein molecule. The result is a looser, less compact structure, changing the original properties of the protein. ...
... – Denaturation breaks the hydrogen bonds that create the twists and turns of a protein molecule. The result is a looser, less compact structure, changing the original properties of the protein. ...
Protein: Amino Acids
... Protein • Essential part of all living cells • Found in animals and plants; Particularly rich in animal foods – meats, poultry, eggs, etc. • Protein is in your skin, hair, nails, muscles, etc. • Made of amino acids – amino acids contain nitrogen, which is necessary for life. ...
... Protein • Essential part of all living cells • Found in animals and plants; Particularly rich in animal foods – meats, poultry, eggs, etc. • Protein is in your skin, hair, nails, muscles, etc. • Made of amino acids – amino acids contain nitrogen, which is necessary for life. ...
Protein: Amino Acids
... Protein • Essential part of all living cells • Found in animals and plants; Particularly rich in animal foods – meats, poultry, eggs, etc. • Protein is in your skin, hair, nails, muscles, etc. • Made of amino acids – amino acids contain nitrogen, which is necessary for life. ...
... Protein • Essential part of all living cells • Found in animals and plants; Particularly rich in animal foods – meats, poultry, eggs, etc. • Protein is in your skin, hair, nails, muscles, etc. • Made of amino acids – amino acids contain nitrogen, which is necessary for life. ...
"Lymphocyte Activation Signals: Transduction".
... a function similar to LAT, but it is expressed in B cells. BLNK is located in the cytoplasm and contains 13 tyrosine residues, many of which become phosphorylated by Syk after BCR crosslinking, allowing molecules with SH2 domains to be recruited. The importance of LAT and BLNK is highlighted by the ...
... a function similar to LAT, but it is expressed in B cells. BLNK is located in the cytoplasm and contains 13 tyrosine residues, many of which become phosphorylated by Syk after BCR crosslinking, allowing molecules with SH2 domains to be recruited. The importance of LAT and BLNK is highlighted by the ...
Feb 26
... promoter is 5' to "coding sequence" 2 elements 1) essential core includes transcription start site 2) UCE (Upstream Control Element) at ~ -100 stimulates transcription 10-100x ...
... promoter is 5' to "coding sequence" 2 elements 1) essential core includes transcription start site 2) UCE (Upstream Control Element) at ~ -100 stimulates transcription 10-100x ...
Characterization of serine/threonine protein phosphatases in
... controlled to a great extent by protein phosphorylation. More specifically, under the conditions utilized in this study, microcystin-LR, calyculin-A and nodularin all completely inhibit PPases 1 and 2A activity at a concentration of ~ 1 - 5 nM, essentially the same concentration at which okadaic aci ...
... controlled to a great extent by protein phosphorylation. More specifically, under the conditions utilized in this study, microcystin-LR, calyculin-A and nodularin all completely inhibit PPases 1 and 2A activity at a concentration of ~ 1 - 5 nM, essentially the same concentration at which okadaic aci ...
Regulation 1. Short term control
... The following example builds on the trp operon to provide not only an illustration of the three different types of short term control in a branched pathway but also another example of long term or transcriptional control. The mode of repressor action in the transcriptional control is exactly analogo ...
... The following example builds on the trp operon to provide not only an illustration of the three different types of short term control in a branched pathway but also another example of long term or transcriptional control. The mode of repressor action in the transcriptional control is exactly analogo ...
Brown eyes, blue eyes. From a gene to its protein
... after a long sought a mutation was discovered – only not at all where they were expecting it! P protein is essential to pigmentation. Although its precise function is unknown, it is a key factor in the synthesis of melanin – the pigment which gives our skin, our hair and our eyes their colour. The m ...
... after a long sought a mutation was discovered – only not at all where they were expecting it! P protein is essential to pigmentation. Although its precise function is unknown, it is a key factor in the synthesis of melanin – the pigment which gives our skin, our hair and our eyes their colour. The m ...
Virtual scrring in
... Autodock • AutoDock has been widely-used and there are many examples of its successful application in the literature: (First clinicaly-approved HIV Integrase Inhibitor – Autodock used during the research – prof. Andrew McCammon) ...
... Autodock • AutoDock has been widely-used and there are many examples of its successful application in the literature: (First clinicaly-approved HIV Integrase Inhibitor – Autodock used during the research – prof. Andrew McCammon) ...
1 slide per page
... - stable, but not rigid, the protein molecules are always in motion - can change due to interaction with other molecules (ions, lipids, other proteins etc) - can change due to phosphorylation (covalent binding of phosphate group) Ca2+- ATPase Ca2+- free ...
... - stable, but not rigid, the protein molecules are always in motion - can change due to interaction with other molecules (ions, lipids, other proteins etc) - can change due to phosphorylation (covalent binding of phosphate group) Ca2+- ATPase Ca2+- free ...
Medical Biochemistry and Molecular Basis of Medical
... c. cannot metabolize leucine and isoleucine. d. All of the above. 14. You and your study partner are having an argument. This time the issue is a patient’s blood urea nitrogen (BUN) level following an overnight fast. After an overnight fast, a patient went to the doctor’s office to have a fasting bl ...
... c. cannot metabolize leucine and isoleucine. d. All of the above. 14. You and your study partner are having an argument. This time the issue is a patient’s blood urea nitrogen (BUN) level following an overnight fast. After an overnight fast, a patient went to the doctor’s office to have a fasting bl ...
Efficient Uniform Isotope Labeling of Proteins Expressed in
... protein (lanes 6 and 7) and another kinase (lanes 8 and 9) in Sf9 cultures after growth in SF900 II medium and medium change to labeling medium BioExpress® 2000-U (lanes 2, 4, 6 and 8) or to expression medium SF900 II (lanes 3, 5, 7 and 9). B: Expression of Abl kinase in presence of 16 µM STI571 af ...
... protein (lanes 6 and 7) and another kinase (lanes 8 and 9) in Sf9 cultures after growth in SF900 II medium and medium change to labeling medium BioExpress® 2000-U (lanes 2, 4, 6 and 8) or to expression medium SF900 II (lanes 3, 5, 7 and 9). B: Expression of Abl kinase in presence of 16 µM STI571 af ...
Promotive effect of brassinosteroids on cell division involves a
... et al., 1999). The ®nding of CycD3 induction by BL suggests that BR may play a promotive role in cell division through CycD3. We therefore carried out a further investigation on the expression of histone H4, a gene whose transcription was regarded as a marker of the S phase in cell division (Reichhe ...
... et al., 1999). The ®nding of CycD3 induction by BL suggests that BR may play a promotive role in cell division through CycD3. We therefore carried out a further investigation on the expression of histone H4, a gene whose transcription was regarded as a marker of the S phase in cell division (Reichhe ...
TLKBio260Exam1Review
... 4. What organisms are found within the category of microbiology? What characteristics make them unique? (2nd 5-min quiz) 5. What types of organisms are found in the domain Eukarya, Bacteria, and Archaea? What is the basis for the classification of organisms into these three domains? How are the orga ...
... 4. What organisms are found within the category of microbiology? What characteristics make them unique? (2nd 5-min quiz) 5. What types of organisms are found in the domain Eukarya, Bacteria, and Archaea? What is the basis for the classification of organisms into these three domains? How are the orga ...
The main actors involved in extending the invertebrate life span
... provided the keys to understand the life span regulation. In the present paper we summarize the mechanisms involved in this process with particular emphasis on the role of the fly fat body. It is interesting to note that pathways which lead to an extension of life span are highly conserved in animal ...
... provided the keys to understand the life span regulation. In the present paper we summarize the mechanisms involved in this process with particular emphasis on the role of the fly fat body. It is interesting to note that pathways which lead to an extension of life span are highly conserved in animal ...
Metabolism
... me by midnight today. As mentioned before, please study the Photosynthesis movie from website, textbook has errors. ...
... me by midnight today. As mentioned before, please study the Photosynthesis movie from website, textbook has errors. ...
2. Summary Final Thesis
... Thank you to Professor Frode Berven, the director of PROBE who trusted in me to let me carry my thesis in his laboratory. He gave me the chance to attend the Bioinformatics for proteomics course that PROBE organized where I have acquired a lot of bioinformatics knowledge and I started to use new pro ...
... Thank you to Professor Frode Berven, the director of PROBE who trusted in me to let me carry my thesis in his laboratory. He gave me the chance to attend the Bioinformatics for proteomics course that PROBE organized where I have acquired a lot of bioinformatics knowledge and I started to use new pro ...
Final Examination
... 27. [5 points] In a protein there is an alpha-helix composed of 11 amino acyl residues. In the folded protein, this alpha-helix lays next to a flat region of a beta-sheet that has hydrophobic amino acids on the surface nearest the alpha-helix. The other side of the alpha-helix is exposed to solvent ...
... 27. [5 points] In a protein there is an alpha-helix composed of 11 amino acyl residues. In the folded protein, this alpha-helix lays next to a flat region of a beta-sheet that has hydrophobic amino acids on the surface nearest the alpha-helix. The other side of the alpha-helix is exposed to solvent ...
Study Guide Nucleotide metabolism 2015
... Study Guide for the following Chapters; Nucleotide Synthesis 1. In the synthesis of IMP, why is the second reaction the first committed step? What other pathways utilize PRPP? 2. What is the rate-limiting step of purine synthesis? 3. How is the purine synthetic pathway controlled? 4. What are the am ...
... Study Guide for the following Chapters; Nucleotide Synthesis 1. In the synthesis of IMP, why is the second reaction the first committed step? What other pathways utilize PRPP? 2. What is the rate-limiting step of purine synthesis? 3. How is the purine synthetic pathway controlled? 4. What are the am ...
Nickel affinity chromatography in Protein purification
... Iminodiacetic acid (IDA) both could be used to purify proteins with histidine molecules. NTA coordinates the Ni2+ with four valences and two valences are available for interaction with imidazole rings of histidine. ...
... Iminodiacetic acid (IDA) both could be used to purify proteins with histidine molecules. NTA coordinates the Ni2+ with four valences and two valences are available for interaction with imidazole rings of histidine. ...
Paracrine signalling
Paracrine signaling is a form of cell-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior or differentiation of those cells. Signaling molecules known as paracrine factors diffuse over a relatively short distance (local action), as opposed to endocrine factors (hormones which travel considerably longer distances via the circulatory system), juxtacrine interactions, and autocrine signaling. Cells that produce paracrine factors secrete them into the immediate extracellular environment. Factors then travel to nearby cells in which the gradient of factor received determines the outcome. However, the exact distance that paracrine factors can travel is not certain.Although paracrine signaling elicits a diverse array of responses in the induced cells, most paracrine factors utilize a relatively streamlined set of receptors and pathways. In fact, different organs in the body -even between different species - are known to utilize a similar sets of paracrine factors in differential development. The highly conserved receptors and pathways can be organized into four major families based on similar structures: Fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective receptor initiates signal transduction cascades, eliciting different responses.