
COMMENTARY REDOX SIGNALLING BY TRANSCRIPTION
... acid (SA) is known as a mediator for systemic acquired resistance, an equivalent of the vertebrate immune response. Recently, the SA-binding protein has been shown to contain catalase activity, which decreases significantly upon ligand binding and thereby results in the accumulation of H2 0 2 [18]. ...
... acid (SA) is known as a mediator for systemic acquired resistance, an equivalent of the vertebrate immune response. Recently, the SA-binding protein has been shown to contain catalase activity, which decreases significantly upon ligand binding and thereby results in the accumulation of H2 0 2 [18]. ...
Adenovirus Overrides Cellular Checkpoints for Protein Translation
... degree of secondary structure in their 5' untranslated regions, including that of many important growth regulatory messages (Fig. 2). For example, mRNAs regulated by mTOR include cyclin D1,8 ornithine decarboxylase,9 and c-myc.10 In this way, mTOR activation is thought to serve as an important check ...
... degree of secondary structure in their 5' untranslated regions, including that of many important growth regulatory messages (Fig. 2). For example, mRNAs regulated by mTOR include cyclin D1,8 ornithine decarboxylase,9 and c-myc.10 In this way, mTOR activation is thought to serve as an important check ...
Protein Quality Matters
... • Topline results: After completing nine months of resistance training, all participants experienced increases in lean muscle mass. The gains for participants consuming whey protein (3.3 kg) were significantly greater than for participants consuming soy protein (1.8 kg), and the whey group had mo ...
... • Topline results: After completing nine months of resistance training, all participants experienced increases in lean muscle mass. The gains for participants consuming whey protein (3.3 kg) were significantly greater than for participants consuming soy protein (1.8 kg), and the whey group had mo ...
Biological Pathways I
... Those that require inputs of energy to proceed are called anabolic pathways ...
... Those that require inputs of energy to proceed are called anabolic pathways ...
Complement - microbiology and immunology on-line
... Activation product of complement proteins (nomenclature) Activated component are usually over-lined: e.g. C1qrs When enzymatically cleaved, the larger moiety, binds to the activation complex or membrane and the smaller peptide is released in the ...
... Activation product of complement proteins (nomenclature) Activated component are usually over-lined: e.g. C1qrs When enzymatically cleaved, the larger moiety, binds to the activation complex or membrane and the smaller peptide is released in the ...
1 1 2 3 4 5 Wnt proteins can direct planar cell polarity in
... Vladar et al., 2012), we examined microtubule orientation at midgastrula stages by monitoring ...
... Vladar et al., 2012), we examined microtubule orientation at midgastrula stages by monitoring ...
Slide 1
... diff sequences determined by the genetic code Native conformation of a protein( unique 3D structure) is determined by the sequence Binding sites are formed after folding, dictating function of the protein ...
... diff sequences determined by the genetic code Native conformation of a protein( unique 3D structure) is determined by the sequence Binding sites are formed after folding, dictating function of the protein ...
Gene Section IDO2 (indoleamine 2,3 dioxygenase 2) -
... expression in a variety of antigen-presenting cell types. Both IDO1 and IDO2 will catabolize tryptophan to kynurenine. Biochemical studies indicate that both enzymes are similarly robust in catabolic activity, although the in vitro conditions required for IDO2 to manifest the same level of activity ...
... expression in a variety of antigen-presenting cell types. Both IDO1 and IDO2 will catabolize tryptophan to kynurenine. Biochemical studies indicate that both enzymes are similarly robust in catabolic activity, although the in vitro conditions required for IDO2 to manifest the same level of activity ...
Polyamines Regulate Growth Factor
... Ji Young Lee, et al:Polyamines Regulate Protein Phosphorylation 199 it was suggested that polyamine may regulate the cell cycle through protein phosphorylation. In breast cancer cell lines it was suggested that signal transduction by the growth factor and E2 may be modulated by polyamine, but the e ...
... Ji Young Lee, et al:Polyamines Regulate Protein Phosphorylation 199 it was suggested that polyamine may regulate the cell cycle through protein phosphorylation. In breast cancer cell lines it was suggested that signal transduction by the growth factor and E2 may be modulated by polyamine, but the e ...
Ribosomes and The Golgi Apparatus
... next amino acid to be brought over. The first amino acid attaches to the next one in line before the tRNA leaves the ribosome. ...
... next amino acid to be brought over. The first amino acid attaches to the next one in line before the tRNA leaves the ribosome. ...
Kinases
... Assuming that each branch point represented a gene duplication event, the immediate ancestral gene as it was at the time of duplication was given a name (fig 1) and a sequence was determined as a consensus sequence of its progeny using its nearest neighbour as an outgroup to determine which amino ac ...
... Assuming that each branch point represented a gene duplication event, the immediate ancestral gene as it was at the time of duplication was given a name (fig 1) and a sequence was determined as a consensus sequence of its progeny using its nearest neighbour as an outgroup to determine which amino ac ...
Cell Molecules * materials for biotechnology
... Typical cell produces 2000 different types of proteins ...
... Typical cell produces 2000 different types of proteins ...
Assaying
... • Very sensitive • Compatible with a wide range of substances • Extinction co-efficient for the dye-protein complex is stable over 10 orders of magnitude (assessed in albumin) • Dye reagent is complex is stable for approximately one hour Disadvantages • Absorbance spectra of the two Coomassie Brilli ...
... • Very sensitive • Compatible with a wide range of substances • Extinction co-efficient for the dye-protein complex is stable over 10 orders of magnitude (assessed in albumin) • Dye reagent is complex is stable for approximately one hour Disadvantages • Absorbance spectra of the two Coomassie Brilli ...
Lecture
... Function: Storage of amino acids Examples: Casein, the protein of milk, is the major source of amino acids for baby mammals. Plants have storage proteins in their seeds. Ovalbumin is the protein of egg white, used as an amino acid source for the developing embryo. ...
... Function: Storage of amino acids Examples: Casein, the protein of milk, is the major source of amino acids for baby mammals. Plants have storage proteins in their seeds. Ovalbumin is the protein of egg white, used as an amino acid source for the developing embryo. ...
Protein Folding
... •combined in various sequences, this array of functional groups accounts for the broad spectrum of protein function. ...
... •combined in various sequences, this array of functional groups accounts for the broad spectrum of protein function. ...
Regeneration and the need for simpler model organisms
... that a deduced history of an extant form must take into account environmental disruptions (an elemental force of natural selection); and second, that the extant form is possible only because stable subsystems were unperturbed by such disturbances. Modular assembly, therefore, provides an error corre ...
... that a deduced history of an extant form must take into account environmental disruptions (an elemental force of natural selection); and second, that the extant form is possible only because stable subsystems were unperturbed by such disturbances. Modular assembly, therefore, provides an error corre ...
Protein structure
... Main-chain N and O atoms are hydrogen-bonded to each other within a helices. (a) Idealized diagram of the path of the main chain in an a helix. Alpha helices are frequently illustrated in this way. There are 3.6 residues per turn in an a helix, which corresponds to 5.4 angstrom (1.5 angstrom per res ...
... Main-chain N and O atoms are hydrogen-bonded to each other within a helices. (a) Idealized diagram of the path of the main chain in an a helix. Alpha helices are frequently illustrated in this way. There are 3.6 residues per turn in an a helix, which corresponds to 5.4 angstrom (1.5 angstrom per res ...
The role of fibroblast growth factor in early Xenopus development
... the report by Smith (1987) of inducing activity secreted by a Xenopus cell line, we turned our attention to an investigation of known growth factors. In our initial screen, we tested a wide range of factors and found only three that were active. These were basic fibroblast growth factor (bFGF), embr ...
... the report by Smith (1987) of inducing activity secreted by a Xenopus cell line, we turned our attention to an investigation of known growth factors. In our initial screen, we tested a wide range of factors and found only three that were active. These were basic fibroblast growth factor (bFGF), embr ...
Lecture 6, Exam III Worksheet Answers
... make one codon into another codon that codes for the exact same amino acid as the first one. 2. Missense mutation- usually causes only minimal damage. These usually change one amino acid into another amino acid; the new a.a. may have properties similar to the first or it may not affect the total pro ...
... make one codon into another codon that codes for the exact same amino acid as the first one. 2. Missense mutation- usually causes only minimal damage. These usually change one amino acid into another amino acid; the new a.a. may have properties similar to the first or it may not affect the total pro ...
About
... solubility: sequence based prediction and experimental verification. Technical University Munich. • Smialowski, P., Schmidt, T., Cox, J., Kirschner, A. and Frishman, D. (2006b) Will my protein crystallize? A ...
... solubility: sequence based prediction and experimental verification. Technical University Munich. • Smialowski, P., Schmidt, T., Cox, J., Kirschner, A. and Frishman, D. (2006b) Will my protein crystallize? A ...
Gene Section NEU3 (sialidase 3 (membrane sialidase)) Atlas of Genetics and Cytogenetics
... tumor cells. Over expression of NEU3 or exogenous addition of lactosylceramide to the cell culture confer resistance to sodium butyrate-induced apoptosis. On the other hand, silencing of NEU3 by siRNA causes induction of apoptosis in cancer cells accompanied with suppression of EGFR signaling, sugge ...
... tumor cells. Over expression of NEU3 or exogenous addition of lactosylceramide to the cell culture confer resistance to sodium butyrate-induced apoptosis. On the other hand, silencing of NEU3 by siRNA causes induction of apoptosis in cancer cells accompanied with suppression of EGFR signaling, sugge ...
Lecture Slides for Protein Structure
... Formed from consecutive sequences Found in proteins w/ different functions result from the physics and chemistry of the structure ...
... Formed from consecutive sequences Found in proteins w/ different functions result from the physics and chemistry of the structure ...
Energetics and Catabolism
... disaccharides, and then to monosaccharides. - Sugar and sugar derivatives, such as amines and acids, are catabolized to pyruvate. Pyruvate and other intermediary products of sugar catabolism are fermented or further catabolized to CO2 and H2O via the TCA cycle. Lipids and amino acids are catabolized ...
... disaccharides, and then to monosaccharides. - Sugar and sugar derivatives, such as amines and acids, are catabolized to pyruvate. Pyruvate and other intermediary products of sugar catabolism are fermented or further catabolized to CO2 and H2O via the TCA cycle. Lipids and amino acids are catabolized ...
Paracrine signalling

Paracrine signaling is a form of cell-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior or differentiation of those cells. Signaling molecules known as paracrine factors diffuse over a relatively short distance (local action), as opposed to endocrine factors (hormones which travel considerably longer distances via the circulatory system), juxtacrine interactions, and autocrine signaling. Cells that produce paracrine factors secrete them into the immediate extracellular environment. Factors then travel to nearby cells in which the gradient of factor received determines the outcome. However, the exact distance that paracrine factors can travel is not certain.Although paracrine signaling elicits a diverse array of responses in the induced cells, most paracrine factors utilize a relatively streamlined set of receptors and pathways. In fact, different organs in the body -even between different species - are known to utilize a similar sets of paracrine factors in differential development. The highly conserved receptors and pathways can be organized into four major families based on similar structures: Fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective receptor initiates signal transduction cascades, eliciting different responses.