
Downstream Processes - Biological Engineering
... – Secondary metabolites – produced during stationary phase • E.g. antibiotics such as penicillin • Sources include fungi, bacteria, plant and animal tissues ...
... – Secondary metabolites – produced during stationary phase • E.g. antibiotics such as penicillin • Sources include fungi, bacteria, plant and animal tissues ...
Intrinsic Protein Disorder and Protein
... corepressor, leading to the initiation of transcription by the coactivator. Type II NRs include NR subfamily 1, and receptor molecules such as retinoic acid receptor (RAR), retinoid x receptor (RXR), thyroid hormone receptor (TR) and vitamin D receptor (VDR). Peroxisome proliferator-activated recept ...
... corepressor, leading to the initiation of transcription by the coactivator. Type II NRs include NR subfamily 1, and receptor molecules such as retinoic acid receptor (RAR), retinoid x receptor (RXR), thyroid hormone receptor (TR) and vitamin D receptor (VDR). Peroxisome proliferator-activated recept ...
Repressilator
... Now, the simulations are shown in the Mathematica file!! We find a steady state, wich is stable for the parameters of the experiment. We change the parameters until the steady state becomes unstable; then we check our model with the experimental results. ...
... Now, the simulations are shown in the Mathematica file!! We find a steady state, wich is stable for the parameters of the experiment. We change the parameters until the steady state becomes unstable; then we check our model with the experimental results. ...
Protein-Misfolding Diseases
... • To help proteins in their folding process • To unfold misfolded proteins before their degradation by the proteasome unit • To protect proteins from interfering interactions during folding ...
... • To help proteins in their folding process • To unfold misfolded proteins before their degradation by the proteasome unit • To protect proteins from interfering interactions during folding ...
Analysis - The Journal of Cell Biology
... long been recognized, an appreciation for the complex and fundamental role of phosphatases is more recent. Through extensive biochemical and genetic analysis, we now know that pathways are not simply switched on with kinases and off with phosphatases. Rather, it is the balance of phosphorylation tha ...
... long been recognized, an appreciation for the complex and fundamental role of phosphatases is more recent. Through extensive biochemical and genetic analysis, we now know that pathways are not simply switched on with kinases and off with phosphatases. Rather, it is the balance of phosphorylation tha ...
Protein Kinase A Activation Down-Regulates, Whereas Extracellular
... Monoaminergic systems are related to the action of methamphetamine and cocaine. Of these, the dopaminergic system plays an important role in the methamphetamine- or cocaine-induced sensitization in animals. There are two superfamilies of dopamine (DA) receptors, designated D1- and D2-like receptors. ...
... Monoaminergic systems are related to the action of methamphetamine and cocaine. Of these, the dopaminergic system plays an important role in the methamphetamine- or cocaine-induced sensitization in animals. There are two superfamilies of dopamine (DA) receptors, designated D1- and D2-like receptors. ...
RBT1, a novel transcriptional co-activator, binds the second subunit
... the proper function of DNA repair proteins involved in damage recognition and excision—interaction with Xeroderma Pigmentosum Complementation Group F (XPF) stimulates its 5′ junction-specific endonuclease activity and interaction with XPG targets this endonuclease to damaged DNA (15,16). The possibi ...
... the proper function of DNA repair proteins involved in damage recognition and excision—interaction with Xeroderma Pigmentosum Complementation Group F (XPF) stimulates its 5′ junction-specific endonuclease activity and interaction with XPG targets this endonuclease to damaged DNA (15,16). The possibi ...
Chapter 2 - Microbial Growth and Nutrition
... a. permeases embedded in membrane function as carrier proteins b. more efficient than passive diffusion (1) more rapid at lower concentrations (2) saturatable (levels off, compared to linear increase with passive diffusion) (3) no energy requirement, still gradient driven (still diffusion) c. permea ...
... a. permeases embedded in membrane function as carrier proteins b. more efficient than passive diffusion (1) more rapid at lower concentrations (2) saturatable (levels off, compared to linear increase with passive diffusion) (3) no energy requirement, still gradient driven (still diffusion) c. permea ...
Protein kinase signaling networks in plant innate immunity
... peptides. These responses mainly mediated through CDPKs are co-regulated by MAPK cascades that can be further modulated by CAM. Ca2+ rise also regulates late responses within hours and days, including the production of SA, phytoalexin, camalexin and other defense compounds through gene regulation. T ...
... peptides. These responses mainly mediated through CDPKs are co-regulated by MAPK cascades that can be further modulated by CAM. Ca2+ rise also regulates late responses within hours and days, including the production of SA, phytoalexin, camalexin and other defense compounds through gene regulation. T ...
Make notes using these questions
... Amino acid R-groups are described as hydrophilic or hydrophobic. What does this mean? Draw a table to show the four levels of protein structure. Include descriptions and diagrams. Bonding is extremely important in protein structure. Describe the types of bonds that would be found at each level of pr ...
... Amino acid R-groups are described as hydrophilic or hydrophobic. What does this mean? Draw a table to show the four levels of protein structure. Include descriptions and diagrams. Bonding is extremely important in protein structure. Describe the types of bonds that would be found at each level of pr ...
Genit 7
... -Clinical pic of these diseases: they are v. much influenced by the environment and other epigenetic characteristics. - IEM: are a large group of hereditary biochemical diseases in which specific gene mutation cause abnormal or missing proteins that lead to alter function. Central Dogma of Genetics ...
... -Clinical pic of these diseases: they are v. much influenced by the environment and other epigenetic characteristics. - IEM: are a large group of hereditary biochemical diseases in which specific gene mutation cause abnormal or missing proteins that lead to alter function. Central Dogma of Genetics ...
Gene Section ALOX15 (arachidonate 15-lipoxygenase) Atlas of Genetics and Cytogenetics
... of 15-hydroxyeicosatetraenoic acid binding to activated peroxisome proliferator-activated receptor gamma transcription factor. J Immunol 2003;170:887-894. Xu B, Bhattacharjee A, Roy B, Xu HM, Anthony D, Frank DA, Feldman GM, Cathcart MK. Interleukin-13 induction of 15lipoxygenase gene expression req ...
... of 15-hydroxyeicosatetraenoic acid binding to activated peroxisome proliferator-activated receptor gamma transcription factor. J Immunol 2003;170:887-894. Xu B, Bhattacharjee A, Roy B, Xu HM, Anthony D, Frank DA, Feldman GM, Cathcart MK. Interleukin-13 induction of 15lipoxygenase gene expression req ...
BIOCHEMISTRY, CELL AND MOLECULAR BIOLOGY TEST Time—170 minutes
... catabolic and anabolic processes is true? a. Anabolic processes create ATP b. Muscle contraction and ion transport are types of anabolic processes c. Carbohydrates and proteins are broken down in anabolic processes d. Catabolism is considered the utilization phase of the energy cycle e. Absorption, ...
... catabolic and anabolic processes is true? a. Anabolic processes create ATP b. Muscle contraction and ion transport are types of anabolic processes c. Carbohydrates and proteins are broken down in anabolic processes d. Catabolism is considered the utilization phase of the energy cycle e. Absorption, ...
Protein - HCC Learning Web
... and transport amino acids to cells protein is made (i.e. synthesized) inside cells according to DNA ...
... and transport amino acids to cells protein is made (i.e. synthesized) inside cells according to DNA ...
Calcium Signaling
... AA-starved mTOR is distributed through the cytoplasm, and becomes localized to lysosomes rapidly on AA feeding ...
... AA-starved mTOR is distributed through the cytoplasm, and becomes localized to lysosomes rapidly on AA feeding ...
a morphogenetic role for the TNF signalling pathway
... TNFα triggers the activation of Cdc42, which leads to filopodium formation and subsequent activation of Rac and Rho (Puls et al., 1999). In endothelial cells, TNFα-induced increases in F-actin levels, stress-fibre formation and cell contraction are associated with a hierarchical activation of Cdc42, ...
... TNFα triggers the activation of Cdc42, which leads to filopodium formation and subsequent activation of Rac and Rho (Puls et al., 1999). In endothelial cells, TNFα-induced increases in F-actin levels, stress-fibre formation and cell contraction are associated with a hierarchical activation of Cdc42, ...
Prezentace aplikace PowerPoint
... • Glycoprotein, essential for formation of elastic fibers (a sheath surrounding the amorphous elastin) • Produced by fibroblasts. • A group of three proteins, fibrillin-1, -2 and -3. • The main role - maintaining the structural integrity of tissues, the regulation of cytokines – TGF-b • In humans, d ...
... • Glycoprotein, essential for formation of elastic fibers (a sheath surrounding the amorphous elastin) • Produced by fibroblasts. • A group of three proteins, fibrillin-1, -2 and -3. • The main role - maintaining the structural integrity of tissues, the regulation of cytokines – TGF-b • In humans, d ...
Allosteric enzymes
... Ca-Calmodulin family of modulator proteins • activated when [Ca2+ ] increases. • Ca2+/calmodulin binds to targets e.g. protein kinases, allosteric result ...
... Ca-Calmodulin family of modulator proteins • activated when [Ca2+ ] increases. • Ca2+/calmodulin binds to targets e.g. protein kinases, allosteric result ...
Gene Section ABL1 (v-abl Abelson murine leukemia viral oncogene homolog 1)
... the membrane-associated c-abl, the myristilated Nterminal end of membrane form can not interact with the kinase c-lobe and it has been suggested that phosphadytilinositol 4-5 bi-phosphate could play an inhibitory role. The autoregulatory mechanism remains functional in the cytoplasmic and nuclear fo ...
... the membrane-associated c-abl, the myristilated Nterminal end of membrane form can not interact with the kinase c-lobe and it has been suggested that phosphadytilinositol 4-5 bi-phosphate could play an inhibitory role. The autoregulatory mechanism remains functional in the cytoplasmic and nuclear fo ...
In Silico Salinispora Dinesh Kumar K. Waheeta Hopper
... e-mail: [email protected] EGFR in lung, head, neck, colon, pancreas, breast, ovary, bladder, kidneys and in gliomas. Expression of EGFR and its role in cancer prognosis have been investigated in many human cancers [6]. The epidermal growth factor (EGF) is the prototype of a family of peptide ...
... e-mail: [email protected] EGFR in lung, head, neck, colon, pancreas, breast, ovary, bladder, kidneys and in gliomas. Expression of EGFR and its role in cancer prognosis have been investigated in many human cancers [6]. The epidermal growth factor (EGF) is the prototype of a family of peptide ...
Protein basics - Crop Genebank Knowledge Base
... Transport (oxygen transfer with haemoglobin) Messengers (insulin and certain other hormones) Antibodies (proteins that bind to specific foreign particles) Regulation (proteins involved in regulating DNA synthesis) ...
... Transport (oxygen transfer with haemoglobin) Messengers (insulin and certain other hormones) Antibodies (proteins that bind to specific foreign particles) Regulation (proteins involved in regulating DNA synthesis) ...
Chapter 3 STRUCTURE AND FUNCTION OF THE CELL
... 4. Secretory Vesicles a. Structure (1) membrane bound spheres that pinch off from the golgi and move to the surface of cell. ...
... 4. Secretory Vesicles a. Structure (1) membrane bound spheres that pinch off from the golgi and move to the surface of cell. ...
Production of Turnip yellow mosaic virus Capsids: The Future in
... Zinc Fingers, Solution? Protein domains that are found in a class of DNA binding proteins Cysteine and histidine residues can bind zinc Competitor with chelators to bind zinc ...
... Zinc Fingers, Solution? Protein domains that are found in a class of DNA binding proteins Cysteine and histidine residues can bind zinc Competitor with chelators to bind zinc ...
Paracrine signalling

Paracrine signaling is a form of cell-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior or differentiation of those cells. Signaling molecules known as paracrine factors diffuse over a relatively short distance (local action), as opposed to endocrine factors (hormones which travel considerably longer distances via the circulatory system), juxtacrine interactions, and autocrine signaling. Cells that produce paracrine factors secrete them into the immediate extracellular environment. Factors then travel to nearby cells in which the gradient of factor received determines the outcome. However, the exact distance that paracrine factors can travel is not certain.Although paracrine signaling elicits a diverse array of responses in the induced cells, most paracrine factors utilize a relatively streamlined set of receptors and pathways. In fact, different organs in the body -even between different species - are known to utilize a similar sets of paracrine factors in differential development. The highly conserved receptors and pathways can be organized into four major families based on similar structures: Fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective receptor initiates signal transduction cascades, eliciting different responses.