Correlations between the Amino Acid and Nucleotide Composition
... To show the extent of the agreement more clearly, a measure of agreement (correlation coefficient) was calculated for each amino acid (or group of amino acids) between the average nucleotide composition of the corresponding bacteriaI codons on the one hand, and the correlation coefficients between t ...
... To show the extent of the agreement more clearly, a measure of agreement (correlation coefficient) was calculated for each amino acid (or group of amino acids) between the average nucleotide composition of the corresponding bacteriaI codons on the one hand, and the correlation coefficients between t ...
Protein Threading - Laboratory of Molecular Modelling
... Property(I) makes the search space exponential in size to the length of the sequence Property(Ii) forces a solution to take ...
... Property(I) makes the search space exponential in size to the length of the sequence Property(Ii) forces a solution to take ...
TIM BARREL
... Out of the 200 residues required to form a TIM barrel, only 160 are considered structurally equivalent between different proteins sharing this fold. The remaining residues are located on the loop regions that link the helices and sheets; the loops at the Cterminal end of the sheets tend to contain t ...
... Out of the 200 residues required to form a TIM barrel, only 160 are considered structurally equivalent between different proteins sharing this fold. The remaining residues are located on the loop regions that link the helices and sheets; the loops at the Cterminal end of the sheets tend to contain t ...
Cells in Vitro - Cancer Research
... growth was particularly interesting, since canava nine is a naturally occurring amino acid. For the purposes of discussion, however, comparisons will be made with microbiological systems, since the authors have been unable to find any studies con cerning canavanine and its effect on tumor growth in ...
... growth was particularly interesting, since canava nine is a naturally occurring amino acid. For the purposes of discussion, however, comparisons will be made with microbiological systems, since the authors have been unable to find any studies con cerning canavanine and its effect on tumor growth in ...
Interpreting the Genetic Code
... The net effect of wobble base pairing is to reduce the number of tRNAs that must be produced by a cell In reality cells do not make 61 different tRNAs, one for each codon Many tRNAs have anticodons that anneal to several different codons\ Codons are known for which there are more than one tRNA, alth ...
... The net effect of wobble base pairing is to reduce the number of tRNAs that must be produced by a cell In reality cells do not make 61 different tRNAs, one for each codon Many tRNAs have anticodons that anneal to several different codons\ Codons are known for which there are more than one tRNA, alth ...
ppt - 3.LF UK 2015
... The figure is found at: http://stallion.abac.peachnet.edu/sm/kmccrae/BIOL2050/Ch1-13/JpegArt113/05jpeg/05_jpeg_HTML/index.htm (December 2006) ...
... The figure is found at: http://stallion.abac.peachnet.edu/sm/kmccrae/BIOL2050/Ch1-13/JpegArt113/05jpeg/05_jpeg_HTML/index.htm (December 2006) ...
Enzyme
... KM of a pair enzyme-substrate a) is decreased by a competitive inhibitor b) is equal to the concentration of a substrate when an activity of the enzyme is maximal c) is increased by a noncompetitive inhibitor d) is directly proportional to an affinity of the enzyme to its substrate ...
... KM of a pair enzyme-substrate a) is decreased by a competitive inhibitor b) is equal to the concentration of a substrate when an activity of the enzyme is maximal c) is increased by a noncompetitive inhibitor d) is directly proportional to an affinity of the enzyme to its substrate ...
Karakterisasi Molekular Fragmen Gen mexB Isolat Pseudomonas
... ABSTRACT Antibiotics have been widely used in the treatment of infectious diseases. However, their effectiveness has been questioned due to the tendency of some bacterial resistance to antibiotics. Pseudomonas aeruginosa among others has been known to be resistant to several antibiotics due to its M ...
... ABSTRACT Antibiotics have been widely used in the treatment of infectious diseases. However, their effectiveness has been questioned due to the tendency of some bacterial resistance to antibiotics. Pseudomonas aeruginosa among others has been known to be resistant to several antibiotics due to its M ...
ijbbaug
... Two isozymes of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase or DS, EC 4.1.2.15) from the callus cultures of Arachis hypogaea L. were resolved by DEAE cellulose column chromatography and characterized using selective assays based on divalent cation requirements and regulation ...
... Two isozymes of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase or DS, EC 4.1.2.15) from the callus cultures of Arachis hypogaea L. were resolved by DEAE cellulose column chromatography and characterized using selective assays based on divalent cation requirements and regulation ...
Document
... • One or two sequences (patches) rich in lysine and arginine • Can be found anywhere in the protein; at the N-terminus, in the middle, or at the C-terminus • PKKKRKV is an example; PKNKRKV is inactive • Attachment of this sequence to normally cytosolic proteins results in the import of such mutated ...
... • One or two sequences (patches) rich in lysine and arginine • Can be found anywhere in the protein; at the N-terminus, in the middle, or at the C-terminus • PKKKRKV is an example; PKNKRKV is inactive • Attachment of this sequence to normally cytosolic proteins results in the import of such mutated ...
Chapter 8- An Introduction to Microbial Metabolism
... electrons and a proton (see glycolysis summary equation). There must be a way to oxidize NADH back to NAD+. In aerobic organisms the NAD+ is regenerated when NADH delivers the H+ and electrons to the electron transport chain. Remember, regardless of the organism, they all use glycolysis as the start ...
... electrons and a proton (see glycolysis summary equation). There must be a way to oxidize NADH back to NAD+. In aerobic organisms the NAD+ is regenerated when NADH delivers the H+ and electrons to the electron transport chain. Remember, regardless of the organism, they all use glycolysis as the start ...
Fatty Acid Metabolism - chem.uwec.edu
... Use of fatty acids in the citric acid cycle requires carbohydrates for the the production of oxaloacetate. During starvation or diabetes, OAA is used to make glucose Fatty acids are then used to make ketone bodies (acetoacetate and D–3–hydroxybutarate) ...
... Use of fatty acids in the citric acid cycle requires carbohydrates for the the production of oxaloacetate. During starvation or diabetes, OAA is used to make glucose Fatty acids are then used to make ketone bodies (acetoacetate and D–3–hydroxybutarate) ...
Amino Acid Catabolism: C
... Methylmalonyl-CoA Mutase catalyzes a molecular rearrangement: the branched C chain of methylmalonyl-CoA is converted to the linear C chain of succinyl-CoA. The carboxyl that is in ester linkage to the thiol of coenzyme A is shifted to an adjacent carbon atom, with opposite shift of a hydrogen atom. ...
... Methylmalonyl-CoA Mutase catalyzes a molecular rearrangement: the branched C chain of methylmalonyl-CoA is converted to the linear C chain of succinyl-CoA. The carboxyl that is in ester linkage to the thiol of coenzyme A is shifted to an adjacent carbon atom, with opposite shift of a hydrogen atom. ...
glucose
... Compartmentation of reactions at phosphoenolpyruvate formation • Carboxylation of pyruvate is located in mitochondrial matrix – at the same time it can serve as anaplerotic reaction of citric acid cycle (se lecture citric acid cycle) • Oxaloacetate cannot be transported across mitochondrial membran ...
... Compartmentation of reactions at phosphoenolpyruvate formation • Carboxylation of pyruvate is located in mitochondrial matrix – at the same time it can serve as anaplerotic reaction of citric acid cycle (se lecture citric acid cycle) • Oxaloacetate cannot be transported across mitochondrial membran ...
Amino Acid Catabolism: C
... Methylmalonyl-CoA Mutase catalyzes a molecular rearrangement: the branched C chain of methylmalonyl-CoA is converted to the linear C chain of succinyl-CoA. The carboxyl that is in ester linkage to the thiol of coenzyme A is shifted to an adjacent carbon atom, with opposite shift of a hydrogen atom. ...
... Methylmalonyl-CoA Mutase catalyzes a molecular rearrangement: the branched C chain of methylmalonyl-CoA is converted to the linear C chain of succinyl-CoA. The carboxyl that is in ester linkage to the thiol of coenzyme A is shifted to an adjacent carbon atom, with opposite shift of a hydrogen atom. ...
Site-directed Mutagenesis of Arginine
... and repair of the heteroduplex DNA molecules that were created during the construction of the mutants. It was not practical to identifY all possible mutants in a replacement set by this strategy, which would require sequencing of over 160 clones to obtain a 95% confidence level of obtaining a comple ...
... and repair of the heteroduplex DNA molecules that were created during the construction of the mutants. It was not practical to identifY all possible mutants in a replacement set by this strategy, which would require sequencing of over 160 clones to obtain a 95% confidence level of obtaining a comple ...
Topic 7: Intro to Metabolism
... Catalase is an enzymes found in almost all cells. Turns H2O2 into H2O and O2 at a rate of 40 million reactions per ...
... Catalase is an enzymes found in almost all cells. Turns H2O2 into H2O and O2 at a rate of 40 million reactions per ...
2ABL
... an organization that guides our current understanding of their biological properties and evolutionary origins. Here, we reveal a structural organization distinct from this traditional hierarchy by statistical analysis of correlated evolution between amino acids. Applied to the S1A serine proteases, ...
... an organization that guides our current understanding of their biological properties and evolutionary origins. Here, we reveal a structural organization distinct from this traditional hierarchy by statistical analysis of correlated evolution between amino acids. Applied to the S1A serine proteases, ...
Serine Protease Mechanism
... If the HIV-1 protease can be selectively inhibited, then new HIV particles cannot form Several novel protease inhibitors are currently marketed as AIDS drugs Many such inhibitors work in a culture dish However, a successful drug must be able to kill the virus in a human subject without blocking othe ...
... If the HIV-1 protease can be selectively inhibited, then new HIV particles cannot form Several novel protease inhibitors are currently marketed as AIDS drugs Many such inhibitors work in a culture dish However, a successful drug must be able to kill the virus in a human subject without blocking othe ...
Chapter 2 - Saladin
... Solutions, Colloids, and Suspensions • Solution—consists of particles of matter called the solute mixed with a more abundant substance (usually water) called the solvent • Solute can be gas, solid, or liquid • Solutions are defined by the following properties: – Solute particles under 1 nm – Solute ...
... Solutions, Colloids, and Suspensions • Solution—consists of particles of matter called the solute mixed with a more abundant substance (usually water) called the solvent • Solute can be gas, solid, or liquid • Solutions are defined by the following properties: – Solute particles under 1 nm – Solute ...
Nucleoside Phosphoramidate Monoesters: Potential
... The accuracy of protein synthesis depends on correct charging of tRNAs with amino acids 1. tRNA synthetases must link tRNAs with their correct amino acids. 2. tRNA synthetases recognize correct amino acids by specific binding to the active site and proofreading. 3. tRNA synthetases recognize correc ...
... The accuracy of protein synthesis depends on correct charging of tRNAs with amino acids 1. tRNA synthetases must link tRNAs with their correct amino acids. 2. tRNA synthetases recognize correct amino acids by specific binding to the active site and proofreading. 3. tRNA synthetases recognize correc ...
Fatty acids with
... In adipocytes and hepatocytes cytosolic [NADPH]/[NADP] ratio is high (~75) – strongly reducing environment In hepatocytes and lactating mammary gland cytosolic NADPH is generated largely by pentose phosphate pathway but malic enzyme is also significant MITOCHONDRION ...
... In adipocytes and hepatocytes cytosolic [NADPH]/[NADP] ratio is high (~75) – strongly reducing environment In hepatocytes and lactating mammary gland cytosolic NADPH is generated largely by pentose phosphate pathway but malic enzyme is also significant MITOCHONDRION ...
Document
... • Inhibitors can block the active site • Inhibitors can pull on another part of the enzyme and stretch the active site out of shape • phosphates and other factors can pull on another part of the enzyme to pull the active site into the correct shape ...
... • Inhibitors can block the active site • Inhibitors can pull on another part of the enzyme and stretch the active site out of shape • phosphates and other factors can pull on another part of the enzyme to pull the active site into the correct shape ...