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Bioactivation of Selenocysteine Se-Conjugates by a Highly Purified
Bioactivation of Selenocysteine Se-Conjugates by a Highly Purified

... its ability to convert leukotriene E4 and 5⬘-S-cysteinyldopamine and by its lower specific activity toward cysteine conjugates of halogenated alkenes (Abraham et al., 1995). Recently, we demonstrated that replacing the sulfur of cysteine S-conjugates by a selenium atom resulted in a dramatic increas ...
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... oxidation of fatty acids Carnitine cycle Beta oxidation Electron transfer to complex II (glutaric aciduria type II) Synthesis of ketone bodies, ketolysis Beta oxidation deficiencies: ...
medical chemistry and biochemistry
medical chemistry and biochemistry

... 4. Compare the results of determining formaldehyde, glucose and sucrose by Fehling's reagent. 5. Compare the most important precipitation and colored chemical reactions for detecting proteins. 6. Compare the results of determining glycine and proteins using the ninhindrin reaction. 7. Analyse variou ...
Word Pro - Sezutsu.lwp
Word Pro - Sezutsu.lwp

... mainly of repetitive units, in which glycine, alanine and serine dominate, making up about 88% of the protein (Zhou et al., 2000). FHC is derived from a single gene that consists of two exons separated by an intron of about 1.0 kb. The first exon encodes only 14 amino acid residues, the second is la ...
Stereochemistry and Mechanism of Reactions Catalyzed by
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... As in the case of other pyridoxal phosphate-containing enzymes which carry out p replacement and/or a$ elimination reactions of amino acids, the reaction sequence leads via a series of aldimine and ketimine complexes between the substrate amino acid and the cofactor to an enzyme-bound Schiff s base ...
Protein Physics by Computer. Step by Step: Protein Visualization
Protein Physics by Computer. Step by Step: Protein Visualization

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... tors with small molecules. N-methyl-D-aspartate (NMDA) receptors have received the most attention culminating in several antagonists, which, however, tend to negatively affect learning and memory (Doble, 1999). An alternative to the blocking of glutamate receptors is to reduce the levels of presynap ...
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... Toxicity of chemicals majorly affects all kinds of plants and animals. Excess of any kind of compounds will be harmful to life [1].Liver plays a major role in detoxification and is generally the major site for intense metabolism[2].It is also a site of biotransformation, of toxic compounds were conv ...
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Complementary DNA Sequence of a Human Cytoplasmic Actin
Complementary DNA Sequence of a Human Cytoplasmic Actin

... Elzinga. 1975: \‘andekerckhove RTW’eber. 1978a.b). Four of these are present in muscle tissue. The other two, /3- and y-a&in, are called cytoplasmic actins and are typical of non-muscle tissue (Vandekerckhove & Weber, 19786). In the human genome. there are more than 20 actin genes as estimated by hy ...
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... insulin, resulting in uptake of dietary fatty acids by that tissue from lipoprotein particles such as chylomicrons, CM (exogenous source) and VLDL(endogenous source). This is facilitated by interaction of LPL with the apoprotein C-II. Glucose but not glycerol is used for re-esterification of these f ...
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Design and analysis of metabolic pathways supporting

... Several natural alternative carbon fixation pathways can support autotrophic growth when the cells are supplied with an electron source. These are reviewed and compared extensively elsewhere [49,65–67]. Notably, to the best of our knowledge, the reductive pentose phosphate pathway is the only carbon ...
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Why Glycogen as an Energy Storage Molecule?

Glycosaminoglycans and Ocular Structures
Glycosaminoglycans and Ocular Structures

... low pH and a host of about 30 degradative enzymes will convert them to simpler molecules that can be reused. Problems arise, however, when for a genetic or other reason some of the degradative enzymes are either missing or nonfunctional. This has also been seen, for example in metabolism in the case ...
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Amino acid synthesis

Amino acid synthesis is the set of biochemical processes (metabolic pathways) by which the various amino acids are produced from other compounds. The substrates for these processes are various compounds in the organism's diet or growth media. Not all organisms are able to synthesise all amino acids. Humans are excellent example of this, since humans can only synthesise 11 of the 20 standard amino acids (aka non-essential amino acid), and in time of accelerated growth, arginine, can be considered an essential amino acid.A fundamental problem for biological systems is to obtain nitrogen in an easily usable form. This problem is solved by certain microorganisms capable of reducing the inert N≡N molecule (nitrogen gas) to two molecules of ammonia in one of the most remarkable reactions in biochemistry. Ammonia is the source of nitrogen for all the amino acids. The carbon backbones come from the glycolytic pathway, the pentose phosphate pathway, or the citric acid cycle.In amino acid production, one encounters an important problem in biosynthesis, namely stereochemical control. Because all amino acids except glycine are chiral, biosynthetic pathways must generate the correct isomer with high fidelity. In each of the 19 pathways for the generation of chiral amino acids, the stereochemistry at the α-carbon atom is established by a transamination reaction that involves pyridoxal phosphate. Almost all the transaminases that catalyze these reactions descend from a common ancestor, illustrating once again that effective solutions to biochemical problems are retained throughout evolution.Biosynthetic pathways are often highly regulated such that building-blocks are synthesized only when supplies are low. Very often, a high concentration of the final product of a pathway inhibits the activity of enzymes that function early in the pathway. Often present are allosteric enzymes capable of sensing and responding to concentrations of regulatory species. These enzymes are similar in functional properties to aspartate transcarbamoylase and its regulators. Feedback and allosteric mechanisms ensure that all twenty amino acids are maintained in sufficient amounts for protein synthesis and other processes.
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