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Understanding an Enzyme Active Site
Understanding an Enzyme Active Site

... Protein secondary structure (alpha helices and beta sheets) provides that stable scaffolding upon which the critical active site amino acids can be precisely positioned in 3D space. The 2-3 amino acids that come together in 3D space to create an enzyme active site are very far apart in the linear se ...
Operon
Operon

... Levels (cont’d) Transcriptional gene regulation  Regulation of which genes are transcribed  Can involve control of the rate at which transcription occurs Posttranscriptional gene regulation  Modifications made to primary transcript in the nucleus ...
Lecture 14: BSCI437 - University of Maryland, College Park
Lecture 14: BSCI437 - University of Maryland, College Park

... – Unwinding a portion of a closed, wound structure creates a topological problem: it causes another region to become over-wound. Can resolve this by creating either single or double stranded breaks, allowing unwinding to occur. This is done by DNA Topoisomerase I or II. ...
ilc April 11, 2013 - Livingston Public Schools
ilc April 11, 2013 - Livingston Public Schools

... bioinformatics, genetic diseases, genetics ofviruses and bacteria, population genetics. MARCH TEST: evolution, phylogeny and sfematics, prokaryotes, protists, fungi, comparative anatomy and physiology ofthe plant kingdom (from green algae to flowering plants - with emphasis on angiosperm form and fu ...
143KB - NZQA
143KB - NZQA

... • described basic functions and/or structures of the molecules involved in protein synthesis e.g. DNA, mRNA, tRNA, ribosome • defined the three different kinds (substitution, deletion, insertion) of mutation • described the difference in inheritance between somatic and gametic mutations • gave an ex ...
Exam #3 Review
Exam #3 Review

... thought to be a potential carcinogen. After incubating the GSA plate, the student notes that there are many more colonies on the plate than are seen on a negative control plate. Which conclusion/s does the student make? a. The chemical tested is a potential carcinogen. b. The chemical tested is not ...
Review Problems #2 (Enzyme Review, Phosphatases
Review Problems #2 (Enzyme Review, Phosphatases

... 2) The branchpoint for aromatic amino acid biosynthesis is chorismate. What is the structure of chorismate? What are the three immediate products derived from chorismate that constitute the first unique steps in the synthesis of the three aromatic amino acids? 3) From where are the two carbons of th ...
Translation - Crestwood Local Schools
Translation - Crestwood Local Schools

... • Proteins are used to build cells and do much of the work inside cells ...
Agrobacterium tumefaciens
Agrobacterium tumefaciens

... The ability of certain membranes to use chemical energy to pump hydrogen ions and then harness the energy stored in the Hydrogen ion gradient to drive cellular work including ATP synthesis. Co factor Any non-protein molecule or ion that is required for the proper functioning of an enzyme. Co factors ...
Organic Chemistry and the Four Classes of Macromolecules PPT
Organic Chemistry and the Four Classes of Macromolecules PPT

... major component of all cell membranes; b/c the phosphate head is hydrophilic and the lipid tail is hydrophobic, they self assemble into a bilayer in water (draw) ...
Human Genetics Albinism pedigree Autosomal or sex
Human Genetics Albinism pedigree Autosomal or sex

... • Caused by a recessive allele • The allele protects heterozygous individuals from the effects of malaria. – The sickled RBCs of heterozygous individuals kill the parasite that causes ...
Cells, Chromosomes, Genes
Cells, Chromosomes, Genes

... Ceiling Principle back in the late 1980s. The idea was to provide the most conservative estimate of probability but in the mid 1990 it fell out of favor Advances in DNA fingerprinting • In the eighties the number of VNTRs used was small, four or less compared to today when the norm is to employ at l ...
No Slide Title
No Slide Title

... even between relatively close species such as Escherichia coli and Haemophilus influenzae (Koonin et al. 1996; Tatusov et al. 1996) • This breakdown in “synteny” (gene order) in prokaryotes is thought to be caused by horizontal gene transfer and also inversions around the origin of replication ...
Gene Section E2F6 (E2F transcription factor 6) Atlas of Genetics and Cytogenetics
Gene Section E2F6 (E2F transcription factor 6) Atlas of Genetics and Cytogenetics

... (2413 bp mRNA), compared to variant 1, that causes a frameshift leading to an early stop codon. This transcript may function in a regulatory role with no protein translated. The predicted protein (isoform b) is much shorter than isoform a. Transcript variants 2 and 4 encode isoform b. Transcript var ...
Severe loss-of-function variants in the genomes of healthy humans James Harraway, Genetic Pathologist
Severe loss-of-function variants in the genomes of healthy humans James Harraway, Genetic Pathologist

... Refinements to software used to predict the functional effect of less severe LOF mutations • Algorithms based on evolutionary conservation should improve with more complete alignments, from increased sequencing of non-human species • Algorithms based on protein structure/function should become more ...
CIVICS AND ECONOMICS
CIVICS AND ECONOMICS

... will be short. If the plant is homozygous, then all the offspring will be tall.  Create a poster, divided into 4 sections, that illustrates the following five types of inheritance: incomplete dominance, codominance, multiple alleles, polygenic traits and sex-linked traits. The poster should include ...
slides
slides

... About  10  million  SNPs  exist  in  human  popula@ons   Most  SNPs  are  outside  of  the  protein  coding  regions   1  SNP  every  600  base  pairs   More  than  5  million  common  SNPs  each  with  frequency  10-­‐50%  account ...
Chapter 13 DNA - Pearson Places
Chapter 13 DNA - Pearson Places

... • discarded by other people or animals (e.g. skin, hair) who have been to the crime scene before collection of samples for forensic analysis • discarded by police or the analyst if correct procedures (e.g. gloves for handling samples) are not followed E3. Discuss the similarities and differences in ...
Genes are on chromosomes
Genes are on chromosomes

... -If they are close, it will happen rarely --> loci said to be linked Distant: -If they are distant, it will happen frequently -->partial linkage 2) More than two chromatids may be involved. ...
Amino Acids
Amino Acids

... When you ingest a protein your body breaks it down into the individual aminos, reorders them, re-folds them, and turns them into whatever is needed by the body at that time. From only 20 amino acids, the body is able to make thousands of unique proteins with different functions. ...
C - mhs
C - mhs

...  A segment of DNA serves as a template for the production of an RNA molecule  The gene unzips and exposes unpaired bases  Serves as template for mRNA formation  Loose RNA nucleotides bind to exposed DNA bases using the C=G and A=U rule  When entire gene is transcribed into mRNA, the result is a ...
Meiosis - Mercer Island School District
Meiosis - Mercer Island School District

... prepared to divide (double size, organelles, and DNA) it goes through 2 cell divisions, to produce 4 haploid cells. Phases of Meiosis: Meiosis also has an interphase period, during which chromosomes are duplicated (sister chromatids). The two sister chromatids are identical copies. The homologous pa ...
ppt
ppt

... – Pain management in cancer patients • Read section 6.4 to find out more about this ...
Chapter 2 Review PPT
Chapter 2 Review PPT

... Subunit used to make proteins made up of a carbon atom attached to a hydrogen, a carboxyl group (-COOH), an amino group (-NH2) , and a variable R group ...
Current Issues in Cr..
Current Issues in Cr..

... of only ~6,500 years, clearly incompatible with the known age of modern humans.” And another reseacher responded to these results in Science vol. 279, 1998; “No one thinks that’s the case, . . .” Emphasis added ...
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Point mutation



A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.
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