HIGH FREQUENCY GENE TARGETING USING INSERTIONAL
... recombination was 1 in 46 (2.2%). This frequency is significantly higher than those reported by two other groups using isogenic DNA sequence replacement constructs (11,12). All three groups were targeting the same region (at and around exon 10 of the Cftr gene), although the replacement targeting co ...
... recombination was 1 in 46 (2.2%). This frequency is significantly higher than those reported by two other groups using isogenic DNA sequence replacement constructs (11,12). All three groups were targeting the same region (at and around exon 10 of the Cftr gene), although the replacement targeting co ...
Prediction of protein function using a deep convolutional
... The CNN architecture employs three computational blocks of consecutive convolutional, batch normalization, rectified linear unit (ReLU) activation, dropout (optionally) and max-pooling layers, and a fully-connected layer. The convolutional layer computes the output of neurons that are connected to l ...
... The CNN architecture employs three computational blocks of consecutive convolutional, batch normalization, rectified linear unit (ReLU) activation, dropout (optionally) and max-pooling layers, and a fully-connected layer. The convolutional layer computes the output of neurons that are connected to l ...
sequence analysis of the 5` coi gene region from dama
... appearance of the Consortium for the Barcoding of Life (CBOL), which proposed as a standard for species identification, a 648bp mtDNA sequence, from the 5’ end of the cytochrome oxidase gene (Hebert et al., 2003, Stoeckle, 2003). For those groups where the COI gene proved unable to distinguish betwe ...
... appearance of the Consortium for the Barcoding of Life (CBOL), which proposed as a standard for species identification, a 648bp mtDNA sequence, from the 5’ end of the cytochrome oxidase gene (Hebert et al., 2003, Stoeckle, 2003). For those groups where the COI gene proved unable to distinguish betwe ...
Organic Chemistry for Biology
... • Smaller organic molecules join together to form larger molecules ...
... • Smaller organic molecules join together to form larger molecules ...
Chromosomal Alterations - ReadingSample - Beck-Shop
... The first cytologist who described chromosome behavior during cell division and how chromosomes move during mitosis was Walter Flemming (1882) in 1882. His terms “prophase,” “metaphase,” and “anaphase” are still used to describe the different steps of mitosis. In 1888 the structures were termed “chr ...
... The first cytologist who described chromosome behavior during cell division and how chromosomes move during mitosis was Walter Flemming (1882) in 1882. His terms “prophase,” “metaphase,” and “anaphase” are still used to describe the different steps of mitosis. In 1888 the structures were termed “chr ...
Document
... carcinomas which are developed at the epithelial or endothelial cells, and sarcomas which are derived from connective tissues. DNA tumor viruses: all three kinds. ...
... carcinomas which are developed at the epithelial or endothelial cells, and sarcomas which are derived from connective tissues. DNA tumor viruses: all three kinds. ...
Molecular Coat Colour Genetics
... substrate for recombination events. Furthermore, nearly identical sequence copies in the genome created by duplications may lead to large-scale chromosomal rearrangements, such as deletions, inversions, translocations and additional duplications. The duplications can harbour large pieces of genetic ...
... substrate for recombination events. Furthermore, nearly identical sequence copies in the genome created by duplications may lead to large-scale chromosomal rearrangements, such as deletions, inversions, translocations and additional duplications. The duplications can harbour large pieces of genetic ...
פרויקט מחקר - בנימין קפא
... • The WT strains morphology is round throughout all the streaks. • In the case of a severe mutation (terD) the morphology is severe in the early passages and it improved during the passages which is believed to be due to an elongation of the telomeres in a recombination pathway. The telomeres shorte ...
... • The WT strains morphology is round throughout all the streaks. • In the case of a severe mutation (terD) the morphology is severe in the early passages and it improved during the passages which is believed to be due to an elongation of the telomeres in a recombination pathway. The telomeres shorte ...
Supplementary Information (doc 33K)
... Supplementary Table 1：Gene-sets significantly associated with narcolepsy The table shows the list of 32 significant gene-sets from both KEGG and the Gene Ontology with FDR 5%. P value was calculated using I(i,j) score. Define indicator I(i,j) = 1 if a sample i carries a CNV overlapping at least one ...
... Supplementary Table 1：Gene-sets significantly associated with narcolepsy The table shows the list of 32 significant gene-sets from both KEGG and the Gene Ontology with FDR 5%. P value was calculated using I(i,j) score. Define indicator I(i,j) = 1 if a sample i carries a CNV overlapping at least one ...
SPINDLY, a tetratricopeptide repeat protein involved in
... foliage, partial male sterility, and parthenocarpic fruit development. However, spy-4 also exhibited obvious partial dominance with respect to flowering time. Under long day conditions, plants heterozygous for spy-4 flowered earlier than wild-type WS plants but later than homozygous spy-4 plants (Ta ...
... foliage, partial male sterility, and parthenocarpic fruit development. However, spy-4 also exhibited obvious partial dominance with respect to flowering time. Under long day conditions, plants heterozygous for spy-4 flowered earlier than wild-type WS plants but later than homozygous spy-4 plants (Ta ...
Amino Acid Metabolism
... • Free amino acids are metabolized in identical ways, regardless of whether they are released from dietary or intracellular proteins • The metabolism of the resulting amino group and nitrogen excretion are a central part of nitrogen ...
... • Free amino acids are metabolized in identical ways, regardless of whether they are released from dietary or intracellular proteins • The metabolism of the resulting amino group and nitrogen excretion are a central part of nitrogen ...
Biochemistry 2000 Sample Questions Proteins
... Solute that diffuses into a bead flows more slowly through the column as the pores restrict flow down the column. (27) The unknown protein must be exposed to conditions that (1) disrupt quaternary structure and (2) maintain quaternary structure. SDS-PAGE in the presence of reducing agent (2-mercapto ...
... Solute that diffuses into a bead flows more slowly through the column as the pores restrict flow down the column. (27) The unknown protein must be exposed to conditions that (1) disrupt quaternary structure and (2) maintain quaternary structure. SDS-PAGE in the presence of reducing agent (2-mercapto ...
Leukaemia Section t(3;4)(p21;q34) Atlas of Genetics and Cytogenetics in Oncology and Haematology
... Note: 3p21 is a recurrent breakpoint in MDS/AML and t-MDS/t-AML suggesting, 3p21 site is likely to contain a gene (genes) involved in the pathogenesis of t(3;4)(p21;q34). Frequent deletion or allelic loss of band 3p21 is common in solid tumors, indicating the presence of tumor suppressor genes on th ...
... Note: 3p21 is a recurrent breakpoint in MDS/AML and t-MDS/t-AML suggesting, 3p21 site is likely to contain a gene (genes) involved in the pathogenesis of t(3;4)(p21;q34). Frequent deletion or allelic loss of band 3p21 is common in solid tumors, indicating the presence of tumor suppressor genes on th ...
HighFour Biology Round 2 Category D: Grades 11 – 12 Tuesday
... The meristematic tissue of plants is composed of a group cells with the ability to keep dividing. Because of its active cell division, meristematic tissues are present near the tips of roots and stems to aid in the lengthening of roots and shoots. ...
... The meristematic tissue of plants is composed of a group cells with the ability to keep dividing. Because of its active cell division, meristematic tissues are present near the tips of roots and stems to aid in the lengthening of roots and shoots. ...
Genetics Practice Test- do and self correct in different color
... c. caused by a dominant gene b. located on the Y chromosome d. sex-linked conditions ____ 37. Sickle-cell anemia is a genetic disease common to human populations from Africa and the Mediterranean coast. The incidence is greater in these regions than elsewhere because the heterozygous state provides ...
... c. caused by a dominant gene b. located on the Y chromosome d. sex-linked conditions ____ 37. Sickle-cell anemia is a genetic disease common to human populations from Africa and the Mediterranean coast. The incidence is greater in these regions than elsewhere because the heterozygous state provides ...
Mitochondrial DNA and Maximum Oxygen Consumption
... electron transport chain to oxygen, thereby altering the capacity for energy production. The first report to address the association between mitochondrial DNA sequences and aerobic performance was by Dionne et al. (1991). Through a 20-week endurance-training program, the authors assessed the relatio ...
... electron transport chain to oxygen, thereby altering the capacity for energy production. The first report to address the association between mitochondrial DNA sequences and aerobic performance was by Dionne et al. (1991). Through a 20-week endurance-training program, the authors assessed the relatio ...
Chapter 11: Gene Expression PPT
... SPI 3210.4.8 Determine the relationship between mutations and human genetic disorders. • SPI 3210.4.9 Evaluate the scientific and ethical issues associated with gene technologies: genetic engineering, cloning, transgenic organism production, stem cell research, and DNA fingerprinting. ...
... SPI 3210.4.8 Determine the relationship between mutations and human genetic disorders. • SPI 3210.4.9 Evaluate the scientific and ethical issues associated with gene technologies: genetic engineering, cloning, transgenic organism production, stem cell research, and DNA fingerprinting. ...
Document
... Secretion of immunodominant membrane protein from onion yellows phytoplasma through the Sec protein-translocation system in Escherichia coli A gene that encodes a putative SecE protein, which is a component of the Sec protein-translocation system, was cloned from the onion yellows phytoplasma (OY). ...
... Secretion of immunodominant membrane protein from onion yellows phytoplasma through the Sec protein-translocation system in Escherichia coli A gene that encodes a putative SecE protein, which is a component of the Sec protein-translocation system, was cloned from the onion yellows phytoplasma (OY). ...
Beanbag Population Genetics
... Evolution is normally studied in terms of populations instead of individuals. In the classroom, it may seem impossible to set up a laboratory procedure that will help students to understand the forces of mutation, migration, random genetic drift, and natural selection -- which all act on populations ...
... Evolution is normally studied in terms of populations instead of individuals. In the classroom, it may seem impossible to set up a laboratory procedure that will help students to understand the forces of mutation, migration, random genetic drift, and natural selection -- which all act on populations ...
2016‐12‐15 1
... What is a DNA molecule? A piece of double stranded DNA (i.e. a double helix of DNA) What is the difference between a chromosome and a chromatid? A replicated chromosome is made up of two chromatids which are joined by the centromere. The chromatids separate from each other during mitosis and is d ...
... What is a DNA molecule? A piece of double stranded DNA (i.e. a double helix of DNA) What is the difference between a chromosome and a chromatid? A replicated chromosome is made up of two chromatids which are joined by the centromere. The chromatids separate from each other during mitosis and is d ...
Genetics—The Study of Inheritance
... How are traits passed from parents to offspring during fertilization? The flower color trait in pea plants can be used as an example. Suppose a hybrid purple-flowered pea plant (one with two different alleles for flower color) is mated with a white-flowered pea plant. What color flowers will the off ...
... How are traits passed from parents to offspring during fertilization? The flower color trait in pea plants can be used as an example. Suppose a hybrid purple-flowered pea plant (one with two different alleles for flower color) is mated with a white-flowered pea plant. What color flowers will the off ...
Molecular Genetics
... Answer: A mutagen in a body cell becomes part of the of the genetic sequence in that cell and in future daughter cells. The cell may die or simply not perform its normal function. These mutations are not passed on to the next generation. When mutations occur in sex cells, they will be present in eve ...
... Answer: A mutagen in a body cell becomes part of the of the genetic sequence in that cell and in future daughter cells. The cell may die or simply not perform its normal function. These mutations are not passed on to the next generation. When mutations occur in sex cells, they will be present in eve ...
Prodigiosin Production in E. Coli
... have been over diluted (we had our samples suspended in 1ml of solution, when Dr. Schwekendiek noted 100µl was the usual dilution) - To rectify this, we concentrated our DNA in a Speed Vacuum Concentrator overnight - After running our samples through the Speed Vacuum Concentrator, we ran them throug ...
... have been over diluted (we had our samples suspended in 1ml of solution, when Dr. Schwekendiek noted 100µl was the usual dilution) - To rectify this, we concentrated our DNA in a Speed Vacuum Concentrator overnight - After running our samples through the Speed Vacuum Concentrator, we ran them throug ...
Point mutation
A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.