Coincidence Detection or Temporal Integration?
... of coordination with the other two neurons during one or more of the three stimuli (airjet 1 or airjet 2 or combined airjet stimulation), but not necessarily in response to the same stimulus. After applying these criteria to our sample of 360 neuronal trios, we identified 26 trios that showed signif ...
... of coordination with the other two neurons during one or more of the three stimuli (airjet 1 or airjet 2 or combined airjet stimulation), but not necessarily in response to the same stimulus. After applying these criteria to our sample of 360 neuronal trios, we identified 26 trios that showed signif ...
All medications can have side effects or unintended effects as part of
... as part of the way in which they are metabolized in the body. It is very important for anyone taking medication either prescribed or over the counter to be aware of what the medication is intended to treat, how it is to be used, what is to be expected from its use and any warning signs of dangerous ...
... as part of the way in which they are metabolized in the body. It is very important for anyone taking medication either prescribed or over the counter to be aware of what the medication is intended to treat, how it is to be used, what is to be expected from its use and any warning signs of dangerous ...
The Optic Tectum in Fishes
... regeneration of axons which may grow into normal and abnormal target areas. Developmental and learning processes involve changes in synaptic arrangement and efficacy. Receptive field Region of retina or visual field within which stimulation alters the activity of a neuron. An electrode that picks up ...
... regeneration of axons which may grow into normal and abnormal target areas. Developmental and learning processes involve changes in synaptic arrangement and efficacy. Receptive field Region of retina or visual field within which stimulation alters the activity of a neuron. An electrode that picks up ...
The Effects of Marijuana - Family Research Council
... manufactured completely from chemical starting materials without using willow bark. The same general approach has been taken with the cannabis plant. In 1964, THC (short-hand for delta-9-tetrahydrocannabinol) was identified as the primary psychoactive ingredient in marijuana. Another very important ...
... manufactured completely from chemical starting materials without using willow bark. The same general approach has been taken with the cannabis plant. In 1964, THC (short-hand for delta-9-tetrahydrocannabinol) was identified as the primary psychoactive ingredient in marijuana. Another very important ...
Medial Prefrontal Cortices Are Unified by Common Connections With Superior
... The monkeys were anesthetized with ketamine hydrochloride (10 mg/kg, intramuscularly) followed by sodium pentobarbital administered intravenously through a femoral catheter until a surgical level of anesthesia was achieved. Additional anesthetic was administered during surgery as needed. Surgery was ...
... The monkeys were anesthetized with ketamine hydrochloride (10 mg/kg, intramuscularly) followed by sodium pentobarbital administered intravenously through a femoral catheter until a surgical level of anesthesia was achieved. Additional anesthetic was administered during surgery as needed. Surgery was ...
AGNP Consensus Guidelines for Therapeutic Drug Monitoring in
... The updated consensus guidelines were prepared by the interdisciplinary TDM group of the AGNP consisting of clinical psychiatrists, pharmacologists, biochemists, pharmacists and chemists from academic and non academic hospitals and institutions of Germany, Switzerland, Austria and Italy, who have be ...
... The updated consensus guidelines were prepared by the interdisciplinary TDM group of the AGNP consisting of clinical psychiatrists, pharmacologists, biochemists, pharmacists and chemists from academic and non academic hospitals and institutions of Germany, Switzerland, Austria and Italy, who have be ...
Omalizumab in ABPA - Stanford University
... 3. Positive immediate skin test or in vitro demonstration of IgE antibody to A. fumigatus 4. One or both of the following: a. Serum precipitins or IgG antibodies to A. fumigatus. b. New or recent abnormalities on chest x-ray (e.g., infiltrates) or chest HRCT (e.g., bronchiectasis, mucus impaction) t ...
... 3. Positive immediate skin test or in vitro demonstration of IgE antibody to A. fumigatus 4. One or both of the following: a. Serum precipitins or IgG antibodies to A. fumigatus. b. New or recent abnormalities on chest x-ray (e.g., infiltrates) or chest HRCT (e.g., bronchiectasis, mucus impaction) t ...
Clinical Trials - Ritonavir
... inhibitor, was approved by the FDA on March 1, 1996 (one day after approval was recommended by the FDA's Antiviral Drugs Advisory Committee). Ritonavir is also known as "Norvir." It belongs to a class of drugs called protease inhibitors. Protease inhibitors are used for the treatment of HIV infectio ...
... inhibitor, was approved by the FDA on March 1, 1996 (one day after approval was recommended by the FDA's Antiviral Drugs Advisory Committee). Ritonavir is also known as "Norvir." It belongs to a class of drugs called protease inhibitors. Protease inhibitors are used for the treatment of HIV infectio ...
BUFADIENOLIDES AND THEIR MEDICINAL UTILITY: A REVIEW Review Article
... triphosphatase sodium-potassium pump (Na+-K+-ATPase), with predilection for its α-1 isoform [54]. This capability enables them to share with other cardiac glycosides the facility to cause an increase in sodium excretion, produce vasoconstriction resulting in hypertension, and act as cardiac inotrope ...
... triphosphatase sodium-potassium pump (Na+-K+-ATPase), with predilection for its α-1 isoform [54]. This capability enables them to share with other cardiac glycosides the facility to cause an increase in sodium excretion, produce vasoconstriction resulting in hypertension, and act as cardiac inotrope ...
Methylphenidate vs. amphetamine: Comparative
... Borcherding, Potter, Mefford, Rapoport, & Keysor, 1990). Presumably resulting from the subtle difference in mechanism of action, there are also behavioral and drug interaction differences in laboratory paradigms and individual patient variation in clinical response. These are reviewed and documented ...
... Borcherding, Potter, Mefford, Rapoport, & Keysor, 1990). Presumably resulting from the subtle difference in mechanism of action, there are also behavioral and drug interaction differences in laboratory paradigms and individual patient variation in clinical response. These are reviewed and documented ...
The Vestibular System
... from the anterior inferior cerebellar artery, mirrors its innervation: The anterior vestibular artery supplies the structures innervated by the superior vestibular nerve, and the posterior vestibular artery supplies the structures innervated by the inferior vestibular nerve. Like most other hair cel ...
... from the anterior inferior cerebellar artery, mirrors its innervation: The anterior vestibular artery supplies the structures innervated by the superior vestibular nerve, and the posterior vestibular artery supplies the structures innervated by the inferior vestibular nerve. Like most other hair cel ...
The Role of Corticotropin-Releasing Factor in Drug Addiction
... that are heterogenously distributed in both brain and peripheral tissues across species. In mammals, the two known native peptide agonists are CRF itself (also abbreviated CRH for corticotropin-releasing hormone) and urocortin. Presently, there are five distinct targets for CRF and urocortin with un ...
... that are heterogenously distributed in both brain and peripheral tissues across species. In mammals, the two known native peptide agonists are CRF itself (also abbreviated CRH for corticotropin-releasing hormone) and urocortin. Presently, there are five distinct targets for CRF and urocortin with un ...
CANNABIDIOL AS AN INTERVENTION FOR ADDICTIVE
... cannabis withdrawal, anxiety and dissociative symptoms during the 11days. - 6 month follow-up showed relapse of cannabis use, but at lower frequency (12/week vs. 7days/7) - CBD is able to antagonize CB1receptor agonist and inhibit reuptake and hydrolysis of anandamide: could be involved in the reduc ...
... cannabis withdrawal, anxiety and dissociative symptoms during the 11days. - 6 month follow-up showed relapse of cannabis use, but at lower frequency (12/week vs. 7days/7) - CBD is able to antagonize CB1receptor agonist and inhibit reuptake and hydrolysis of anandamide: could be involved in the reduc ...
Pharmaceutical Administration and Regulations in Japan
... promotion of R&D, production, distribution policies, and drug pricing, i.e., functions related to pharmaceutical companies. The Pharmaceuticals and Medical Devices Evaluation Center (Evaluation Center) in the National Institute of Health Sciences was established to strengthen approval reviews on Jul ...
... promotion of R&D, production, distribution policies, and drug pricing, i.e., functions related to pharmaceutical companies. The Pharmaceuticals and Medical Devices Evaluation Center (Evaluation Center) in the National Institute of Health Sciences was established to strengthen approval reviews on Jul ...
In Vivo and In Vitro Antimalarial Activity of 4Nerolidylcatechol
... habitat and occur in humid, partially shaded areas where they receive abundant indirect and some direct sunlight, such as at forest edges, trails, roadsides and typically where anthropogenic alteration of forest has occurred. Both plants are morphologically very similar, the most ostensible differen ...
... habitat and occur in humid, partially shaded areas where they receive abundant indirect and some direct sunlight, such as at forest edges, trails, roadsides and typically where anthropogenic alteration of forest has occurred. Both plants are morphologically very similar, the most ostensible differen ...
Summary of Main DRUID Results - Druid
... common toxicological finding after alcohol. Amphetamine use more common in northern Europe; cocaine use more prevalent in southern Europe. Killed drivers: THC was number four (range 0- 6.1%), after alcohol, benzodiazepines and amphetamines. Combined user (alcohol-drug and drug-drugs): The majority o ...
... common toxicological finding after alcohol. Amphetamine use more common in northern Europe; cocaine use more prevalent in southern Europe. Killed drivers: THC was number four (range 0- 6.1%), after alcohol, benzodiazepines and amphetamines. Combined user (alcohol-drug and drug-drugs): The majority o ...
The Neuroscientist
... location of sounds, and document how neurons across multiple auditory cortical fields might represent these as trains of action potentials. They conclude by asking whether neurons in different regions of the auditory cortex might not be simply sensitive to each of these three sound features but whet ...
... location of sounds, and document how neurons across multiple auditory cortical fields might represent these as trains of action potentials. They conclude by asking whether neurons in different regions of the auditory cortex might not be simply sensitive to each of these three sound features but whet ...
Liposomes in drug delivery
... in a rigid, well-ordered arrangement ('Solid' gellike phase) below the To, and in a liquid-crystalline ('Fluid') phase above the To. The fluidity of liposome bilayers can be altered by using phospholipids with different T~ which in turn can vary from - 2 0 to 90°C depending upon the length and natur ...
... in a rigid, well-ordered arrangement ('Solid' gellike phase) below the To, and in a liquid-crystalline ('Fluid') phase above the To. The fluidity of liposome bilayers can be altered by using phospholipids with different T~ which in turn can vary from - 2 0 to 90°C depending upon the length and natur ...
pps
... CYP 2B6 absent in 3-4 % of the caucasian population CYP 2C9 deficit in 1-3 % of the caucasian population CYP 2C19 individues with inactiv enzyme (3-6 % of the caucasian and 15-20 % of the asian population) ...
... CYP 2B6 absent in 3-4 % of the caucasian population CYP 2C9 deficit in 1-3 % of the caucasian population CYP 2C19 individues with inactiv enzyme (3-6 % of the caucasian and 15-20 % of the asian population) ...
Optimal Recall from Bounded Metaplastic Synapses: Predicting
... storing information, metaplastic synapses were found to perform equally poorly when the amount of recalled information was measured instead [22], indicating that much of the information laid down in the synapses remained inaccessible for the standard attractor dynamics used at retrieval. Thus, perha ...
... storing information, metaplastic synapses were found to perform equally poorly when the amount of recalled information was measured instead [22], indicating that much of the information laid down in the synapses remained inaccessible for the standard attractor dynamics used at retrieval. Thus, perha ...
How effective delays shape oscillatory dynamics in neuronal networks
... for different conduction velocities for separate excitatory and inhibitory populations can lead to bifurcations of localized bump states to breathers and traveling pulses [19]. Although the presence of time delays in the nervous system are most often associated with axonal propagation, significant t ...
... for different conduction velocities for separate excitatory and inhibitory populations can lead to bifurcations of localized bump states to breathers and traveling pulses [19]. Although the presence of time delays in the nervous system are most often associated with axonal propagation, significant t ...
The psychophisiology of pain: a literature review - Reciis
... occur through change of temperature (thermal stimulus), osmotic difference or tissue distension (mechanic stimulus), hypoxia or tissue injury followed by inflammation (chemical stimulus), promotes a local release of chemical mediators like bradykinine, protons, hystamine, serotonin, arachidonic acid ...
... occur through change of temperature (thermal stimulus), osmotic difference or tissue distension (mechanic stimulus), hypoxia or tissue injury followed by inflammation (chemical stimulus), promotes a local release of chemical mediators like bradykinine, protons, hystamine, serotonin, arachidonic acid ...
primary visual cortex and visual awareness
... rather than hard-wired. Perhaps the information represented in V1 is necessary only for certain types of awareness (such as figure–ground segmentation, perception during focal attention, perception of low-level features and so on). Some theories consider consciousness in terms of a dynamic, global n ...
... rather than hard-wired. Perhaps the information represented in V1 is necessary only for certain types of awareness (such as figure–ground segmentation, perception during focal attention, perception of low-level features and so on). Some theories consider consciousness in terms of a dynamic, global n ...
Marijuana: Facts and Myths - livedrugfree.org
... These endogenous cannabinoids help control a wide array of mental and physical processes in the brain and throughout the body, Walker, M.J.; Huang, S.M.; Strangman, N.M.; Tsou, K.; and Sanudo-Pena, M.C. Pain modulation by the release of the endogenous cannabinoid anandamide. Proceedings of the Nat ...
... These endogenous cannabinoids help control a wide array of mental and physical processes in the brain and throughout the body, Walker, M.J.; Huang, S.M.; Strangman, N.M.; Tsou, K.; and Sanudo-Pena, M.C. Pain modulation by the release of the endogenous cannabinoid anandamide. Proceedings of the Nat ...