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Specific Drug - Auburn School District
Specific Drug - Auburn School District

... chemical in it called tetrahydrocannabinol, better known as THC. All forms of marijuana are mind-altering (psychoactive). In other words, they change how the brain works. A lot of other chemicals are found in marijuana, too — about 400 of them, some of which are carcinogenic. Marijuana is addictive ...
Lugaro, Ernesto
Lugaro, Ernesto

... “When many axonal terminals belonging to neurons of different kinds and endowed with different specific secretions converge onto the same neuron, their actions can reinforce or hinder each other, giving rise to the phenomena of facilitation or inhibition” (Lugaro, 1909b, p. 52). Lugaro and the glia ...
Animal senses: how do they perceive the world and what important
Animal senses: how do they perceive the world and what important

... upon which the primary senses function. This will hopefully provide a useful guide to understanding both the nature of individual sensory experiences and the defining criteria required for establishing additional sensory modalities. ...
Models of retinotopic development - damtp
Models of retinotopic development - damtp

... Many computational models have been proposed for the formation of retinotopic maps (Goodhill and Xu, 2005; Goodhill, 2007), and show how retinotopic order might interact with the development of other map properties, such as ocular dominance or orientation preference (Swindale, 1996). Recent experime ...
Motivation, Addiction & Eating
Motivation, Addiction & Eating

... • Stimulation experiments in humans are much more difficult, but there have been rare opportunities with surgery (epilepsy) patients. • The patients report pleasure from some sites. • Patients will also continuously stimulate certain areas that do not produce a pleasurable experience. i.e. the rewar ...
chapter 16 neuropsychology lecture notes
chapter 16 neuropsychology lecture notes

... assuming that patients just received sensations from one side of space. This study showed that hemineglect was not simply due to a sensory problem. 5. What do we still need to know? There are different types of hemineglect produced by damage in different parts of the brain. Thus it is not clear if t ...
Zzzzzzz…. - The Cambridge MRCPsych Course
Zzzzzzz…. - The Cambridge MRCPsych Course

... • Competitive antagonists useful to reverse effects of benzodiazepines • Flumazenil often used in benzodiazepine overdose or for treatment of comatose patient suspected of overdose • 200µg IV over 15 seconds • Further 100µg IV over 10 seconds after one minute if no response. Max 1mg. • t1/2 1-2 hour ...
A Novel Tissue Protective Peptide: Cyclic Helix B Peptide
A Novel Tissue Protective Peptide: Cyclic Helix B Peptide

... in renal IR injury in a murine model, in terms of decreased apoptosis, pro-inflammatory cytokines expression and complement activation [6]. The main mechanism is the binding to the tissue protective receptor (TPR), which is a heterodimer receptor composed of EPO receptor (EPOR) and β common receptor ...
cardiovascular drugs and autacoids
cardiovascular drugs and autacoids

... 1- Fenoldopam is a peripheral arteriolar dilator used for hypertensive emergencies And postoperative hypertension with renal compromised function. 2- Mechanism of Action A selective postsynaptic dopamine agonist (D1-receptors) which exerts hypotensive effects by decreasing peripheral vasculature res ...
RECENT ADVANCES IN BRAIN TARGETED DRUG DELIVERY SYSTEMS: A REVIEW
RECENT ADVANCES IN BRAIN TARGETED DRUG DELIVERY SYSTEMS: A REVIEW

... Drug delivery to the Central Nervous System (CNS) in treatment of CNS related disorders is very complicated and challenging. Although some neuropharmaceutical agents have great potential for treating CNS disorders, major challenge to CNS drug delivery is the Blood Brain Barrier (BBB), which limits t ...
Saladin, Human Anatomy 3e
Saladin, Human Anatomy 3e

... 5. The neural components of the eye are the retina and optic nerve. The retina absorbs light, partially processes the visual information, and encodes the stimulus in action potentials conducted via the optic nerve to the brain. The sharpest vision occurs in a region of retina called the fovea centra ...
Extrastriatal and striatal D 2 dopamine receptor blockade with
Extrastriatal and striatal D 2 dopamine receptor blockade with

... 20 h after the last evening dose of the antipsychotic, in order to avoid the peak plasma concentration following the drug dose intake. All patients were medicated for at least 15 days, which is much longer than the five half-lives necessary to reach the steady state for plasma antipsychotic concentr ...
The Human Brain
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Human Pregnane X Receptor - Clinical Cancer Research
Human Pregnane X Receptor - Clinical Cancer Research

... enzyme gene transcription, it would be ideal to develop chemotherapy drugs that do not activate hPXR.This report describes studies undertaken to explore the characteristics of hPXR stimulation and mechanisms of drug-receptor interactions in vitro with new anti-tubulin drugs. Experimental Design: In ...
The Autonomic Nervous System
The Autonomic Nervous System

... Figure 17-02b ...
This guide is for middle and high school students participating... of the Human Brain and Sheep Brain Dissections.  Programs... Distance Learning Program
This guide is for middle and high school students participating... of the Human Brain and Sheep Brain Dissections. Programs... Distance Learning Program

... constituting the nerves outside the central nervous system and including the cranial nerves, spinal nerves, and sympathetic and parasympathetic nervous systems. Pia Mater - The fine vascular membrane that closely envelops the brain and spinal cord under the arachnoid and the dura mater. Pituitary Gl ...
Melatonin modulates autophagy through a redox
Melatonin modulates autophagy through a redox

... porphyrin biosynthesis, wherein the female glands display an extraordinarily high concentration of porphyrins. Damage derived from this production of porphyrins, mediated by reactive oxygen species, causes the glands to develop autophagic processes, which culminate in detachment-derived cell death; ...
NS pdf
NS pdf

... 1. Impulse arrives at the presynaptic terminal axon. 2. This impulse causes Ca++ to enter the axon knob. 3. The Ca++ causes synaptic vesicles to migrate to the presynaptic membrane and release hundreds of neurotransmitters into the synaptic cleft. 4. Neurotransmitter binds with receptors on the post ...
Consciousness Operates Beyond the Timescale
Consciousness Operates Beyond the Timescale

... rather than quantum system, however his reasoning is based on biological inconsistency. Here we present detailed exposition of molecular neurobiology and define the dynamical timescale of cognitive processes linked to consciousness to be 10-15 picoseconds showing that macroscopic quantum coherent ph ...
Hallucinogens - People Server at UNCW
Hallucinogens - People Server at UNCW

... Preclinical research • Serotonin depletion, damage to serotonergic neurons reported in several species including rats and primates (see Morton, 2005 for a review) • Effects were present in primate brain 7 years after MDMA exposure Hatzidimitrious et al., 1999) ...
Regents Biology
Regents Biology

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Z333 Lecture

... Action Potential (AP): The electrical signal passed along a neuron • At rest, neurons maintain an electrical difference across their membrane (pg. 666) • (-) inside cell; (+) outside cell • During action potential, charges flip • Action potential propagated down axon ...
Nervous System Project
Nervous System Project

... Nerve cells work by a mixture of chemical and electrical action. ...
ppt
ppt

... Converted to the active form which covalently binds the H+/K+ ATPase enzyme and inactivates it. Have short half lives but effect lasts for 24 hours. At least 18 hours are required for synthesis of new pump molecules. Inhibit both fasting & meal-stimulated secretion (90-98% of 24-hour secretion). The ...
Lecture Outline
Lecture Outline

... K+ is higher than at rest, so the membrane potential is closer to EK than it is at the resting potential. The K+ channels eventually close, and the membrane potential returns to the resting potential. ...
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Neuropsychopharmacology

Neuropsychopharmacology, an interdisciplinary science related to psychopharmacology (how drugs affect the mind) and fundamental neuroscience, is the study of the neural mechanisms that drugs act upon to influence behavior. It entails research of mechanisms of neuropathology, pharmacodynamics (drug action), psychiatric illness, and states of consciousness. These studies are instigated at the detailed level involving neurotransmission/receptor activity, bio-chemical processes, and neural circuitry. Neuropsychopharmacology supersedes psychopharmacology in the areas of ""how"" and ""why"", and additionally addresses other issues of brain function. Accordingly, the clinical aspect of the field includes psychiatric (psychoactive) as well as neurologic (non-psychoactive) pharmacology-based treatments.Developments in neuropsychopharmacology may directly impact the studies of anxiety disorders, affective disorders, psychotic disorders, degenerative disorders, eating behavior, and sleep behavior.The way fundamental processes of the brain are being discovered is creating a field on par with other “hard sciences” such as chemistry, biology, and physics, so that eventually it may be possible to repair mental illness with ultimate precision. An analogy can be drawn between the brain and an electronic device: neuropsychopharmacology is tantamount to revealing not only the schematic diagram, but the individual components, and every principle of their operation. The bank of amassed detail and complexity involved is huge; mere samples of some of the details are given in this article.
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