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Short-term memory
Short-term memory

... by their short-term (milliseconds to a few seconds) activities (x i,yj ). The units store information by changing their synaptic weights (W ), with long-lasting effects (days, years). Information can be stored over intermediate time scales of seconds, minutes or hours by short-term memory elements, ...
An Optogenetic Approach to Understanding the Neural Circuits of Fear
An Optogenetic Approach to Understanding the Neural Circuits of Fear

... here). This approach has not been demonstrated for PV interneurons, however, and can be nonoptimal for targeting specific cell populations. This is because most viruses have limited packaging capacity, making it necessary to use truncated versions of tissue specific promoters, which can reduce cell- ...
Exploration of Variability of Arkypallidal and Prototypical Projections
Exploration of Variability of Arkypallidal and Prototypical Projections

... 1 Introduction ...
Physiology – how the body detects pain stimuli
Physiology – how the body detects pain stimuli

... wounds is an effective and safe therapy (Farley, 2011). ...
Opioid Pharmacology
Opioid Pharmacology

... drug class specific withdrawal syndrome that can be produced by abrupt cessation, rapid dose reduction, decreasing blood level of the drug, and/or administration of an antagonist. ...
Drug Induced Phospholipidosis and Steatosis
Drug Induced Phospholipidosis and Steatosis

... • Phospholipidosis does not necessarily constitute toxicity, and can resolve by itself, but it predicts drug or metabolite accumulation that have led to liver, kidney, or respiratory failure. Consequently, in 2004 the FDA formed the Phospholipidosis Working Group to study the problem3,4 and recomme ...
Antimycobacterial Drugs (抗分枝杆菌药)
Antimycobacterial Drugs (抗分枝杆菌药)

... Significant and at times treatment-limiting adverse effects, including bone marrow suppression and irreversible peripheral and optic neuropathy, have been reported with the prolonged courses of therapy that are necessary for treatment of tuberculosis. Although linezolid may eventually prove to be an ...
Slide 1
Slide 1

... • Identify the signs of addiction and discuss types of addictions, including compulsive behaviors such as gambling and shopping. • Identify the six categories of drugs and distinguish between drug misuse and drug abuse. • Discuss the issues of over-the-counter and prescription drug misuse and abuse, ...
No Slide Title - Vanderbilt University Medical Center
No Slide Title - Vanderbilt University Medical Center

... No response/side effects Substitute drug from Opposite arm ...
action potential
action potential

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Emotion, Memory and the Brain - sdsu
Emotion, Memory and the Brain - sdsu

... same way that other events do—via transmission to the lateral nucleus. Although our experiments had identified a subcortical sensory pathway that gave rise to fear conditioning, we did not dismiss the importance of the cortex. The interaction of subcortical and cortical mechanisms in emotion remains ...
Nerves, structures, and organs of the head 1. Left cerebral
Nerves, structures, and organs of the head 1. Left cerebral

... Fornix (6) An arch of fold found in the cerebral hemispheres of man, Medulla oblongata (15) Composed primarily of white matter, the medulla communicates between the higher brain centers and the spinal cord. Midbrain (13) Also called the mesencephalon, it is located between the diencephalon and the p ...
The Cerebral Cortex
The Cerebral Cortex

... The main part of the brain is the cerebrum – big piece of folded, wrinkly meat that covers the older more primitive limbic system & brainstem. -Gyri are the grooves in the brain & Sulci are the humps in between the grooves. Newer neural networks within the cerebrum form specialized work teams that e ...
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Cell assemblies in the cerebral cortex Günther Palm, Andreas
Cell assemblies in the cerebral cortex Günther Palm, Andreas

... to do justice to the connectivity in large brains. An indication for this are the horizontal stripes of myelinated fibers within the gray matter which were known in the human cortex since the times of Gennari (1782) and Baillarger (1840) and which contributed to the myeloarchitectonic differentiatio ...
Poster Session Abstract Booklet - The New York Academy of Sciences
Poster Session Abstract Booklet - The New York Academy of Sciences

... Afferent fibers of the vagus nerve serve as a conduit for peripheral neural networks to continually inform the central nervous system of the body’s physiological status. Part of this information includes the immunological status of the host, which is processed by the brain to send an appropriate eff ...
Neuroprotection in Dementia
Neuroprotection in Dementia

Journal Club_CLINICAL EFFICACY OF REPEAT BRAIN CT
Journal Club_CLINICAL EFFICACY OF REPEAT BRAIN CT

... • After repeat brain CT scans, 28(47%)of the patients in group 2 ,comprising 17% of the entire population in this study group, underwent neurosurgical interventions. • Of the 28 surgically treated patients of group 2 ,6(10%) exhibited neurological worsening and 22(37%) appear neurologically stable. ...
Competitive advantage
Competitive advantage

... • This has recently been proved by Novartis in a phase IIa POC study. • No other competing projects identified in clinical development. *Datamonitor, Epidatabase (2003) **IMS Data ...
The Cl Area of the Brainstem in Tonic and Reflex
The Cl Area of the Brainstem in Tonic and Reflex

... mediated solely by epinephrine. Although iontophoretically applied epinephrine inhibits rather than excites preganglionic sympathetic cells, 33 it is conceivable that RVL neurons use another transmitter that may be coreleased with epinephrine to produce sympathoexcitation. Among the candidates are n ...
Lecture 16
Lecture 16

... Leaky integrate and fire neurons Encode each individual spike Time is represented exactly Each spike has an associated time The timing of recent incoming spikes determines whether a neuron will fire • Computationally expensive • Can we do almost as well without encoding every single spike? ...
21. Basal ganglion
21. Basal ganglion

... It originates from small structure is located beneath the thalamus, lying against the medial surface of the internal capsule. It has the appearance of a biconvex lens in coronal section. They pass laterally through the internal capsule forming the subthalamic fasciculus and terminate in both segment ...
Induction and Maintenance Therapy
Induction and Maintenance Therapy

... mixture of antibodies against lymphocyte receptors and adhesion molecules with consequent lymphocyte depletion but also significant downregulation or binding of other receptors and new mechanisms of immunosuppression, such as apoptosis of activated lymphocytes, which could be important in tolerance ...
fluctuations in somatosensory responsiveness and baseline firing
fluctuations in somatosensory responsiveness and baseline firing

... decreases) were observed (Fig. 1). The magnitudes of these fluctuations over time are shown in Fig. 2B. Mean baseline activity tended to decrease non-significantly in both groups at 10 min and 40 min and to be slightly decreased or unchanged at 100 min. Separation of these fluctuations into increase ...
Revisão - Química Nova
Revisão - Química Nova

... the presynaptic calcium channel, thereby preventing the release of neurotransmitters.27 The therapeutic benefit of this drug stems from its potent and selective blockade of neuronal-type voltage-sensitive calcium channels, so this compound represents a new class of N-type calcium channel blocker age ...
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Neuropsychopharmacology

Neuropsychopharmacology, an interdisciplinary science related to psychopharmacology (how drugs affect the mind) and fundamental neuroscience, is the study of the neural mechanisms that drugs act upon to influence behavior. It entails research of mechanisms of neuropathology, pharmacodynamics (drug action), psychiatric illness, and states of consciousness. These studies are instigated at the detailed level involving neurotransmission/receptor activity, bio-chemical processes, and neural circuitry. Neuropsychopharmacology supersedes psychopharmacology in the areas of ""how"" and ""why"", and additionally addresses other issues of brain function. Accordingly, the clinical aspect of the field includes psychiatric (psychoactive) as well as neurologic (non-psychoactive) pharmacology-based treatments.Developments in neuropsychopharmacology may directly impact the studies of anxiety disorders, affective disorders, psychotic disorders, degenerative disorders, eating behavior, and sleep behavior.The way fundamental processes of the brain are being discovered is creating a field on par with other “hard sciences” such as chemistry, biology, and physics, so that eventually it may be possible to repair mental illness with ultimate precision. An analogy can be drawn between the brain and an electronic device: neuropsychopharmacology is tantamount to revealing not only the schematic diagram, but the individual components, and every principle of their operation. The bank of amassed detail and complexity involved is huge; mere samples of some of the details are given in this article.
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