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Uniform Inhibition of Dopamine Neurons in the Ventral Tegmental
Uniform Inhibition of Dopamine Neurons in the Ventral Tegmental

... (Fig. 3, A and B). The probability that an action potential occurred in a burst was also reduced during the pinch (Fig. 3C), which shows that the reduction in burst number is not simply a result of a reduction in the number of action potentials. We found no correlation between the effects of the ave ...
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... begin first to attempt to reduce modifiable risk factors. The patient should be reevaluated in about 2 months to see if blood pressure has been lowered. If it has not, drug therapy may be necessary. ...
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... antibiotics were given post-operatively with epithelial healing rate, pain or visual acuity being markers in the study. The authors found no statistically significant differences in the treatment groups for any parameter measured. This is perhaps not surprising since these two drugs are anti-bacteri ...
DISSOCIATION OF TARGET SELECTION AND SACCADE
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as a PDF here

... moment (www.cypalleles.ki.se)). These variant alleles can be divided in functional alleles (like *1, *2, *35, encoding normal activity), null alleles (like *3, *4, *5, encoding no activity at all) and decreased activity alleles (like *9, *10, *41), encoding enzymes with residual metabolic capacity. ...
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Antiviral Agents: Structural Basis of Action and Rational Design

... whether the drug has a measurable benefit or advantage over other treatments with a relatively large number of patients (usually >100 patients for antiviral drugs). Phase IV includes all studies carried out after approval of the drug and may address many different issues, from side-effects to effica ...
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Neuropsychopharmacology

Neuropsychopharmacology, an interdisciplinary science related to psychopharmacology (how drugs affect the mind) and fundamental neuroscience, is the study of the neural mechanisms that drugs act upon to influence behavior. It entails research of mechanisms of neuropathology, pharmacodynamics (drug action), psychiatric illness, and states of consciousness. These studies are instigated at the detailed level involving neurotransmission/receptor activity, bio-chemical processes, and neural circuitry. Neuropsychopharmacology supersedes psychopharmacology in the areas of ""how"" and ""why"", and additionally addresses other issues of brain function. Accordingly, the clinical aspect of the field includes psychiatric (psychoactive) as well as neurologic (non-psychoactive) pharmacology-based treatments.Developments in neuropsychopharmacology may directly impact the studies of anxiety disorders, affective disorders, psychotic disorders, degenerative disorders, eating behavior, and sleep behavior.The way fundamental processes of the brain are being discovered is creating a field on par with other “hard sciences” such as chemistry, biology, and physics, so that eventually it may be possible to repair mental illness with ultimate precision. An analogy can be drawn between the brain and an electronic device: neuropsychopharmacology is tantamount to revealing not only the schematic diagram, but the individual components, and every principle of their operation. The bank of amassed detail and complexity involved is huge; mere samples of some of the details are given in this article.
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