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Physiological Plasticity of Single Neurons in Auditory Cortex of the
Physiological Plasticity of Single Neurons in Auditory Cortex of the

... phase. The criterion of learning was five consecutive dilation responses to the CS greater than the sensitization reference level; the fifth consecutive trial was noted as the trial(s) to criterion. This criterion was met in 17 of the 19 sessions in which acoustically evoked dilations were recorded. ...
hypothalamus, pit..
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... blood flow to the adenohypophysis or anterior pituitary gland. The posterior pituitary gland is supplied almost entirely by the inferior hypophyseal artery. Because most of the blood flow to the anterior pituitary gland is from the portal system, it is possible, on occasions, for the gland to outgro ...
Biotechnology
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Neural Interaction in Cat Primary Auditory Cortex. Dependence on
Neural Interaction in Cat Primary Auditory Cortex. Dependence on

... L in layers I-III of the primary auditory cortex suggest that most of the tangential labeling of axon collaterals of the pyramidal cells proceeds in a dorsoventral direction, i.e., within isofrequency sheets. However, additional patches occur over 1 mm anterior or posterior of the injection site and ...
Cerebellar fastigial nucleus: from anatomic construction to
Cerebellar fastigial nucleus: from anatomic construction to

... and interneurons, with long axons projecting out of the cerebellar nuclei and short axons connecting only with neurons within the FN, respectively [1, 14]. Based on the transmitter phenotypes, glutamatergic, GABAergic as well as glycinergic neurons have been identified in the FN [1, 14, 15]. In addi ...
Chapter 12 – Auditory Localization and Organization
Chapter 12 – Auditory Localization and Organization

... It’s been suggested that in mammals, there are fewer more broadly tuned neurons, ones that fire Forgettabout what’s below this box. over a wide range of locations to the right and others that fire over a wide range of locations to the left. The blue curve is of a neuron that responds above its base ...
The Nervous System Introduction Organization of Neural Tissue
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... tensions, and the like” in the 1940s and 50s – Involves cutting or scraping away most of the connections to and from the prefrontal cortex – Some patients died on the table or later committed suicide – Some were severely brain damaged or developed seizures – Some patients saw improvement of symptoms ...
The Neural Basis of the Object Concept in Ambiguous and
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... some stimuli as a matter of illusion arouse the perception of an object where no object really exists. Cases of non-uniformity, ambiguity and illusionary perception not only challenge the applicability of the Gestalt principles, but also provide an interesting test for our hypothesis about the neura ...
CASSIA ITALICA Research Article SERMAKKANI, M. AND V. THANGAPANDIAN
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... The methanolic extract of the leaves of Cassia italica was investigated for its anti inflammatory activity in animal models. The extract at different doses used showed good anti inflammatory activity which has been done significantly, by the formation of oedema induced by carrageenan and formalin. T ...
Original article Anti-hepatitis B virus activity in vitro of combinations
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... AD38 cells express high levels of wild-type HBV (genotype  D and subtype ayw) from an integrated HBV genome under the transcriptional control of a tetracycline-­controllable promoter (tetracycline-off and HBV expressed after removal of tetracycline) [32]. To test anti-HBV activity of various nucleos ...
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Implications on visual apperception: energy, duration
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Glia-Derived D-Serine Controls NMDA Receptor Activity and
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... from that observed in DAAO-treated virgin slices (p > 0.05; Figures 2A and 2B). Since AMPAR-mediated responses in SON neurons are not altered by lactation (Oliet et al., 2001; Stern et al., 2000), such a change in the ratio implies a change in NMDAR-mediated EPSCs. Because different NR2 subunits con ...
false positive and false negative results in urine drug screening tests
false positive and false negative results in urine drug screening tests

... with immunoassays and cause false-positives. Most have only been documented in case reports. Table 2 shows substances reported to cause falsepositive results using immunoassay. This list may not include all potential substances. The frequency of false-positive results depends on the specificity of i ...
Pharmacology
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... 3The drug’s rate of absorption through various membranes. 4The formulation of the dose. N.B. :- The onset of action is especially variable after oral administration depending on the presence of food in the stomach, the motility of the GI tract and other factors. Peak of activity:When the drug reache ...
Pharmacodynamic and pharmacokinetic drug interactions
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... health problem both for individuals and the community. Despite this, there is limited information in the literature regarding drug interaction categories responsible for causing ADRs. In this study we investigated the drug combinations most frequently co-reported as interacting in the WHO Global Ind ...
Preclinical Toxicology of Anticancer Agents
Preclinical Toxicology of Anticancer Agents

... study suggested that Phase 1 clinical trials could be safely initiated at a dose one-third that of the animal MTD. The mouse was as useful as any other species in this regard. Homan (8) applied regression analysis to the MTO's of 25 anticancer drugs for dog and monkey. It was estimated that one-tent ...
Social Networking and Benzodiazepine Withdrawal
Social Networking and Benzodiazepine Withdrawal

... benzodiazepines, both positive and negative? 3. What do they need to help them in the process of withdrawal? 4. What is the process of withdrawal like? ...
Neural Control of Interappendage Phase During Locomotion
Neural Control of Interappendage Phase During Locomotion

... moving at the same low speed, (B) both treadmills moving at the same high speed, and (C) one treadmill moving at the low speed of condition A and the other treadmill moving at the high speed of condition B. In conditions A and B the right and left legs alternate as in normal walking. The results in ...
New anti-tuberculosis drugs and regimens: 2015 update
New anti-tuberculosis drugs and regimens: 2015 update

... threat to TB control and elimination [4, 5, 8, 9]. A recent study demonstrated that while in Germany the MDR-TB treatment-related costs exceed €50 000 [8], in Europe, the average cost to treat a single XDR-TB case is over €160 000 [8]. The largest meta-analytic study presently available revealed tha ...
Processing in layer 4 of the neocortical circuit: new insights from
Processing in layer 4 of the neocortical circuit: new insights from

... place in cortical layer 4. These pictures suggest that, as befits its position, the response tuning of layer 4 cells is largely determined by feed-forward input, including feedforward inhibition (inhibition from interneurons driven by the thalamus) as well as feed-forward excitation (directly from t ...
Alcohol Drugs and the Workplace
Alcohol Drugs and the Workplace

... “A complex disorder with biological mechanisms affecting the brain and its capacity to control substance use. It is not only determined by biological and genetic factors but psychological, social, cultural and environmental factors as well. Currently there are no means of identifying those who will ...
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Jeopardy Template

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In Vitro Study of The Effect of Some Drugs on Leishmania Donavani
In Vitro Study of The Effect of Some Drugs on Leishmania Donavani

... Other antileishmanials such as amphotericin B, paromomycin, pentamidin, and miltefosin are available in cases where antimonials lack efficacy, but their therapeutic windows are limited .thus, the development of a novel & better anti-leishmanials is necessary to meet an urgent medical need on a globa ...
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Neuropsychopharmacology

Neuropsychopharmacology, an interdisciplinary science related to psychopharmacology (how drugs affect the mind) and fundamental neuroscience, is the study of the neural mechanisms that drugs act upon to influence behavior. It entails research of mechanisms of neuropathology, pharmacodynamics (drug action), psychiatric illness, and states of consciousness. These studies are instigated at the detailed level involving neurotransmission/receptor activity, bio-chemical processes, and neural circuitry. Neuropsychopharmacology supersedes psychopharmacology in the areas of ""how"" and ""why"", and additionally addresses other issues of brain function. Accordingly, the clinical aspect of the field includes psychiatric (psychoactive) as well as neurologic (non-psychoactive) pharmacology-based treatments.Developments in neuropsychopharmacology may directly impact the studies of anxiety disorders, affective disorders, psychotic disorders, degenerative disorders, eating behavior, and sleep behavior.The way fundamental processes of the brain are being discovered is creating a field on par with other “hard sciences” such as chemistry, biology, and physics, so that eventually it may be possible to repair mental illness with ultimate precision. An analogy can be drawn between the brain and an electronic device: neuropsychopharmacology is tantamount to revealing not only the schematic diagram, but the individual components, and every principle of their operation. The bank of amassed detail and complexity involved is huge; mere samples of some of the details are given in this article.
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