Related File
... Since officers started carrying Narcan in October 2010, 163 doses have been administered, resulting in 157 overdose reversals. In the 18 months before October 2010, there were 46 overdose related deaths. In the 18 months after the implementation of the Narcan program there were 22 overdose related ...
... Since officers started carrying Narcan in October 2010, 163 doses have been administered, resulting in 157 overdose reversals. In the 18 months before October 2010, there were 46 overdose related deaths. In the 18 months after the implementation of the Narcan program there were 22 overdose related ...
Brain-to-text: decoding spoken phrases from phone
... of phonetic representations that can be decoded continuously during speech production. At the same time, the neural pathways represented within our model offer a glimpse into the complex dynamics of the brain’s fundamental building blocks during speech production. ...
... of phonetic representations that can be decoded continuously during speech production. At the same time, the neural pathways represented within our model offer a glimpse into the complex dynamics of the brain’s fundamental building blocks during speech production. ...
Pharmacodynamic Effects of a D-Amino Acid Oxidase Inhibitor
... Inhibition of D-amino acid oxidase (DAAO) activity is a potential target for the treatment of chronic pain. Here we characterized the effects of systemic administration of the DAAO inhibitor 4Hfuro[3,2-b]pyrrole-5-carboxylic acid (SUN) in rat models of neuropathic and inflammatory pain. Oral adminis ...
... Inhibition of D-amino acid oxidase (DAAO) activity is a potential target for the treatment of chronic pain. Here we characterized the effects of systemic administration of the DAAO inhibitor 4Hfuro[3,2-b]pyrrole-5-carboxylic acid (SUN) in rat models of neuropathic and inflammatory pain. Oral adminis ...
Weight Gain - Obesity Action Coalition
... What causes medicationrelated weight gain? Sometimes it is not the drug itself causing weight gain; however, it is the side-effects from the drug. Some drugs stimulate your appetite, and as a result, you eat more. Others may affect how your body absorbs and stores glucose, which can lead to fat depo ...
... What causes medicationrelated weight gain? Sometimes it is not the drug itself causing weight gain; however, it is the side-effects from the drug. Some drugs stimulate your appetite, and as a result, you eat more. Others may affect how your body absorbs and stores glucose, which can lead to fat depo ...
Body System Adverse Effects
... Classroom Response Question When providing teaching for a patient who is prescribed a selective serotonin reuptake inhibitor (SSRI), which statement will the nurse include? A. The SSRI will work faster than the older tricyclic antidepressants. B. The SSRI will have an immediate beneficial effect on ...
... Classroom Response Question When providing teaching for a patient who is prescribed a selective serotonin reuptake inhibitor (SSRI), which statement will the nurse include? A. The SSRI will work faster than the older tricyclic antidepressants. B. The SSRI will have an immediate beneficial effect on ...
Machine Learning
... • Our brain is dominated by the cerebral cortex, a very complex structure of billions of neurons and hundreds of billions of synapses. • The cortex includes areas that are responsible for different human activities (motor, visual, auditory, somatosensory, etc.), and associated with different sensory ...
... • Our brain is dominated by the cerebral cortex, a very complex structure of billions of neurons and hundreds of billions of synapses. • The cortex includes areas that are responsible for different human activities (motor, visual, auditory, somatosensory, etc.), and associated with different sensory ...
Superior Colliculus and Visual Spatial Attention
... both the stimulus-driven and top-down factors that regulate spatial attention and saccade selection (Fecteau & Munoz 2006). Although SC activity may have been restricted to spatial attention associated with eye movements, other studies have shown that the SC may play a role in covert attention. In o ...
... both the stimulus-driven and top-down factors that regulate spatial attention and saccade selection (Fecteau & Munoz 2006). Although SC activity may have been restricted to spatial attention associated with eye movements, other studies have shown that the SC may play a role in covert attention. In o ...
neurophysics.ucsd.edu
... by Welker in rats [5]. These behaviors involve the use of common muscles in the snout [4,17], and their robust oneto-one coordination suggests that they might depend on a common rhythm generator. Since Welker’s initial qualitative observations, synchronous sniffing and whisking has been more complet ...
... by Welker in rats [5]. These behaviors involve the use of common muscles in the snout [4,17], and their robust oneto-one coordination suggests that they might depend on a common rhythm generator. Since Welker’s initial qualitative observations, synchronous sniffing and whisking has been more complet ...
Motor systems Basal ganglia
... regulate movement. Without information from the basal ganglia, the cortex is unable to properly direct motor control, and the deficits seen in Parkinson’s and Huntington’s disease and related movement disorders become apparent. Let’s start with the anatomy of the basal ganglia. The important “player ...
... regulate movement. Without information from the basal ganglia, the cortex is unable to properly direct motor control, and the deficits seen in Parkinson’s and Huntington’s disease and related movement disorders become apparent. Let’s start with the anatomy of the basal ganglia. The important “player ...
post-radioteraphy
... Non-enhanced CT (A) shows a hypodense area (black arrow) in contiguity to a skull fracture in a patient with head trauma. SWI (B) & SWI-Phase (C) reveal hemorrhagic in the lesion (black arrow) & adjacent subarachnoid space compatible with adjacent subcortical hemorrhagic axonal injury. Note that blo ...
... Non-enhanced CT (A) shows a hypodense area (black arrow) in contiguity to a skull fracture in a patient with head trauma. SWI (B) & SWI-Phase (C) reveal hemorrhagic in the lesion (black arrow) & adjacent subarachnoid space compatible with adjacent subcortical hemorrhagic axonal injury. Note that blo ...
The Distribution of Chandelier Cell Axon Terminals that Express the
... analyzed (Figs 7 and 8). The significance of the comparisons between the different layers across the different areas analyzed is illustrated in Table 1. In general, when significant differences were observed in the density of GAT-ir Ch-terminals between areas, they were mostly due to significant differ ...
... analyzed (Figs 7 and 8). The significance of the comparisons between the different layers across the different areas analyzed is illustrated in Table 1. In general, when significant differences were observed in the density of GAT-ir Ch-terminals between areas, they were mostly due to significant differ ...
Prodrugs:
... for improving site specificity, prodrugs to bypass high first-pass metabolism, prodrugs for improving stability, prodrugs for reducing adverse effects, prodrugs for improving drug targeting, and prodrugs for improving absorption and bioavailability, or according to, 3. The nature of the chemical lin ...
... for improving site specificity, prodrugs to bypass high first-pass metabolism, prodrugs for improving stability, prodrugs for reducing adverse effects, prodrugs for improving drug targeting, and prodrugs for improving absorption and bioavailability, or according to, 3. The nature of the chemical lin ...
DOWN - Ubiquitous Computing Lab
... INT Winner; /* - last winner in Kohonen layer */ REAL Alpha; /* - learning rate for Kohonen layer */ REAL Alpha_; /* - learning rate for output layer */ REAL Alpha__; /* - learning rate for step sizes */ ...
... INT Winner; /* - last winner in Kohonen layer */ REAL Alpha; /* - learning rate for Kohonen layer */ REAL Alpha_; /* - learning rate for output layer */ REAL Alpha__; /* - learning rate for step sizes */ ...
aad2355_ArticleContent_toSPI 15Jan16_MLF
... and tolerability in preclinical models with less frequent dosing. Accurins specifically, and nanotechnology in general, can increase the therapeutic index of molecularly targeted agents, including kinase inhibitors targeting cell cycle and oncogenic signal transduction pathways, which have to date p ...
... and tolerability in preclinical models with less frequent dosing. Accurins specifically, and nanotechnology in general, can increase the therapeutic index of molecularly targeted agents, including kinase inhibitors targeting cell cycle and oncogenic signal transduction pathways, which have to date p ...
Letter to the Editor - Drug Metabolism and Disposition
... omeprazole. One formulation contained EE (40 g) and LNG (60 g), whereas the second contained LNG (60 g) and was devoid of EE. The combination of EE and LNG increased both the area under the plasma concentration vs. time curve of omeprazole (38%) and the omeprazole to 5-hydroxy omeprazole area und ...
... omeprazole. One formulation contained EE (40 g) and LNG (60 g), whereas the second contained LNG (60 g) and was devoid of EE. The combination of EE and LNG increased both the area under the plasma concentration vs. time curve of omeprazole (38%) and the omeprazole to 5-hydroxy omeprazole area und ...
Abnormal Magnetic Resonance Imaging and Hemichorea
... also proposed as a potential pathological mechanism explaining the CT and MRI changes associated with non-ketotic hyperglycemia [7]. Complete or partial resolution of the basal ganglia hyperintensity, as was seen in both our cases, refutes this theory and suggests an alternative mechanism(s). In the ...
... also proposed as a potential pathological mechanism explaining the CT and MRI changes associated with non-ketotic hyperglycemia [7]. Complete or partial resolution of the basal ganglia hyperintensity, as was seen in both our cases, refutes this theory and suggests an alternative mechanism(s). In the ...
Porphyrin Metabolism & Porphyrias
... Cytochrome P450 Monooxygenase System: • Cytochrome P450s (CYPs) are actually a superfamily of related, hemecontaining monooxygenase enzymes that participate in abroad variety of reactions. This system performs different functions in two separate locations in cells. • The over-all reaction catalyzed ...
... Cytochrome P450 Monooxygenase System: • Cytochrome P450s (CYPs) are actually a superfamily of related, hemecontaining monooxygenase enzymes that participate in abroad variety of reactions. This system performs different functions in two separate locations in cells. • The over-all reaction catalyzed ...
Basal Ganglia: Internal Organization
... and in this focal plane gives rise to four primary dendrites. The dendrites are initially spine free and then become densely laden with spines, usually after the first bifurcation. An individual MSN possesses 10 000–15 000 spines, each of which receives a glutamatergic input at its head (see Figure ...
... and in this focal plane gives rise to four primary dendrites. The dendrites are initially spine free and then become densely laden with spines, usually after the first bifurcation. An individual MSN possesses 10 000–15 000 spines, each of which receives a glutamatergic input at its head (see Figure ...
ISSN 2167-910X - International Scientific Indexing
... Serious considerations by regulatory authorities are taken to safeguard the patient’s right, safety and wellbeing involved in a clinical trial. In addition considerations like International Conference on Harmonization (ICH) guidelines, Investigational New Drug (IND) application, New Drug Application ...
... Serious considerations by regulatory authorities are taken to safeguard the patient’s right, safety and wellbeing involved in a clinical trial. In addition considerations like International Conference on Harmonization (ICH) guidelines, Investigational New Drug (IND) application, New Drug Application ...
Role of the Basal Ganglia in the Control of Purposive - lsr
... ent opinions on the definition (106), the basal ganglia, as a functional entity, are composed of the caudate nucleus (CD) and putamen (PUT) (collectively called striatum), globus pallidus, substantia nigra, and subthalamic nucleus (STN).1 The globus pallidus is further divided into the external segm ...
... ent opinions on the definition (106), the basal ganglia, as a functional entity, are composed of the caudate nucleus (CD) and putamen (PUT) (collectively called striatum), globus pallidus, substantia nigra, and subthalamic nucleus (STN).1 The globus pallidus is further divided into the external segm ...
invariant face and object recognition in the visual system
... generalization to similar stimuli (in the Hamming distance sense, see Rolls and Treves, 1997), graceful degradation (fault tolerance), and some locality to the representation, so that some single neurons which receive inputs from such a representation can obtain sufficient information without requir ...
... generalization to similar stimuli (in the Hamming distance sense, see Rolls and Treves, 1997), graceful degradation (fault tolerance), and some locality to the representation, so that some single neurons which receive inputs from such a representation can obtain sufficient information without requir ...
Obesity in DSM-5
... psychiatric disorders is likely to involve examination of these phenomena across psychiatric classes to identify neurobiological factors that underlie phenotypic similarities (eg, binge eating in mood disorder, BED, and borderline personality disorder) and distinguish lean from obese individuals. A ...
... psychiatric disorders is likely to involve examination of these phenomena across psychiatric classes to identify neurobiological factors that underlie phenotypic similarities (eg, binge eating in mood disorder, BED, and borderline personality disorder) and distinguish lean from obese individuals. A ...
Serotonin synthesis, release and reuptake in terminals: a
... http://www.tbiomed.com/content/7/1/34 ...
... http://www.tbiomed.com/content/7/1/34 ...
Neuron-Glia Interactions of Rat Hippocampal Cells in vitro: Glial
... Video-enhanced dtyerential interference microscopy. For video microscopy, hippocampal cells were harvested on E20 and plated in glass coverslip microcultures pretreated with Matrigel. After 24 hr in vitro, the medium was changed to L15 medium supplemented with horse serum (10%) and glucose (8 mM), a ...
... Video-enhanced dtyerential interference microscopy. For video microscopy, hippocampal cells were harvested on E20 and plated in glass coverslip microcultures pretreated with Matrigel. After 24 hr in vitro, the medium was changed to L15 medium supplemented with horse serum (10%) and glucose (8 mM), a ...
In 1998 the Lancet published an editorial entitled “the - HAL
... All participants annually received a computerised neuropsychometric examination, ECO (examen cognitif par ordinateur). This assesses primary memory, verbal and visuospatial secondary memory, language skills (word and syntax comprehension, naming, verbal fluency), visuospatial performance (ideational ...
... All participants annually received a computerised neuropsychometric examination, ECO (examen cognitif par ordinateur). This assesses primary memory, verbal and visuospatial secondary memory, language skills (word and syntax comprehension, naming, verbal fluency), visuospatial performance (ideational ...