Environmental Impact of Antibiotics and Tetracycline on
... and other biological tests to be conducted. (Origin of Antibiotics) Since that time few other antibiotics of such widespread effect suitable for use in humans have been found. The British drug and chemical industry could not make the large amounts of penicillin made necessary by World War II. Theref ...
... and other biological tests to be conducted. (Origin of Antibiotics) Since that time few other antibiotics of such widespread effect suitable for use in humans have been found. The British drug and chemical industry could not make the large amounts of penicillin made necessary by World War II. Theref ...
Grid Cell Firing May Arise From Interference of Theta Frequency
... for grid cell properties, but is specifically indicated by the pattern of experimental results described above. Other models designed to show grid cell firing properties based on network dynamics (Fuhs and Touretzky, 2006) cannot be derived from the constraints of this data on intrinsic oscillation fr ...
... for grid cell properties, but is specifically indicated by the pattern of experimental results described above. Other models designed to show grid cell firing properties based on network dynamics (Fuhs and Touretzky, 2006) cannot be derived from the constraints of this data on intrinsic oscillation fr ...
Clinical pharmacology of anti-infectives and nonsteroidal_англ
... 21. Isoniazid-induced liver damage: A. occurs primarily in patients under 30 years of age B. occurs with increased frequency in patients receiving concomitant ethambutol therapy C. *is probably due to the formation of a toxic hydrazine metabolite that binds to liver protein D. is frequently associat ...
... 21. Isoniazid-induced liver damage: A. occurs primarily in patients under 30 years of age B. occurs with increased frequency in patients receiving concomitant ethambutol therapy C. *is probably due to the formation of a toxic hydrazine metabolite that binds to liver protein D. is frequently associat ...
1 - The University of Liverpool Repository
... inspired the development of most marketed antimalarials, however it is also associated with well-defined toxicological issues. Until very recently quinine has been the backbone of the standard of care defined by WHO in the treatment of cerebral malaria. Quinine has diverse pharmacological portfolio. ...
... inspired the development of most marketed antimalarials, however it is also associated with well-defined toxicological issues. Until very recently quinine has been the backbone of the standard of care defined by WHO in the treatment of cerebral malaria. Quinine has diverse pharmacological portfolio. ...
Morphology of HRP-Injected Spinocervical Tract Neurons: Effect of
... dorsal rhizotomy in adults has been reported to causeeither substantialdendritic atrophy (Brown et al., 1979)or no change (Brown et al., 1983). Brown et al.‘s (1979) study wascarried out usingthe Golgi method, which provides an incomplete view of cellswhoseidentity (e.g., spinocervical, postsynaptic ...
... dorsal rhizotomy in adults has been reported to causeeither substantialdendritic atrophy (Brown et al., 1979)or no change (Brown et al., 1983). Brown et al.‘s (1979) study wascarried out usingthe Golgi method, which provides an incomplete view of cellswhoseidentity (e.g., spinocervical, postsynaptic ...
the medial division of the medial geniculate body of the cat
... The structure of neurons and axons was studied in the medial division of the medial geniculate body of the cat with the Golgi methods. The results show that the medial division consists of morphologically heterogeneous neurons. The main types, in descending order of frequency, are medium-sized neuro ...
... The structure of neurons and axons was studied in the medial division of the medial geniculate body of the cat with the Golgi methods. The results show that the medial division consists of morphologically heterogeneous neurons. The main types, in descending order of frequency, are medium-sized neuro ...
Gregory W. Albers, Sven Jacobson, J. Marc Simard and Barney J
... The present study examined a potential pharmacotherapy for the prevention of edema after ischemia in humans. The main finding of this study is that our protocol for administering RP-1127 to critically ill patients with stroke is feasible. No safety concerns, hypoglycemia, or drug-related serious adv ...
... The present study examined a potential pharmacotherapy for the prevention of edema after ischemia in humans. The main finding of this study is that our protocol for administering RP-1127 to critically ill patients with stroke is feasible. No safety concerns, hypoglycemia, or drug-related serious adv ...
Selective Inhibitors of Picornavirus Replication
... rhinoviruses, FMDV, CVB3, and TMEV.40,44–47 In addition to CAR, several coxsackieviruses can use DAF as an additional receptor.48–50 The use of additional receptors for infection of picornaviruses may have implications for drug therapy, considering that a virus could escape inhibition by a drug that ...
... rhinoviruses, FMDV, CVB3, and TMEV.40,44–47 In addition to CAR, several coxsackieviruses can use DAF as an additional receptor.48–50 The use of additional receptors for infection of picornaviruses may have implications for drug therapy, considering that a virus could escape inhibition by a drug that ...
Prescribing Information
... suicidal ideation) has been reported with EDURANT. Patients with severe depressive symptoms should seek immediate medical evaluation to assess the possibility that the symptoms are related to EDURANT, and if so, to determine whether the risks of continued therapy outweigh the benefits. During the Ph ...
... suicidal ideation) has been reported with EDURANT. Patients with severe depressive symptoms should seek immediate medical evaluation to assess the possibility that the symptoms are related to EDURANT, and if so, to determine whether the risks of continued therapy outweigh the benefits. During the Ph ...
Managing Epileptic Dogs
... is to add a second drug before adequate serum concentrations of the first drug are achieved. Several alternative medicaitons are available for the management of epileptic dogs that are truly refractory to phenobarbital. The addition of potassium bromide improves seizure control in approximately 80% ...
... is to add a second drug before adequate serum concentrations of the first drug are achieved. Several alternative medicaitons are available for the management of epileptic dogs that are truly refractory to phenobarbital. The addition of potassium bromide improves seizure control in approximately 80% ...
Anticonvulsants as mood stabilisers
... Cl ion fluxes; (b) decrease in excitatory (particularly glutamate-mediated) processes, involving Mg2+and Ca2+ion fluxes; and (c) modulation of membrane cation conductance (Na+, Ca2*or K+)by effects on membrane receptors or transport mechanisms for these ions which modulate signal transduction in the ...
... Cl ion fluxes; (b) decrease in excitatory (particularly glutamate-mediated) processes, involving Mg2+and Ca2+ion fluxes; and (c) modulation of membrane cation conductance (Na+, Ca2*or K+)by effects on membrane receptors or transport mechanisms for these ions which modulate signal transduction in the ...
The cerebrocerebellar system: anatomic substrates of the cerebellar
... and brain structures known to be associated with a wide array of non-motor behaviors. The cerebellum has interconnections with brainstem and thalamic reticular systems that subserve arousal. Autonomic activity is supported by the reciprocal interconnections with the hypothalamus. Limbic and paralimb ...
... and brain structures known to be associated with a wide array of non-motor behaviors. The cerebellum has interconnections with brainstem and thalamic reticular systems that subserve arousal. Autonomic activity is supported by the reciprocal interconnections with the hypothalamus. Limbic and paralimb ...
Saffron (Crocus sativus L.) and morphine
... ethanolic extracts and crocin may have interaction with the opioid system to reduce withdrawal syndrome (Hosseinzadeh H. 2010). Alcohol extract of Crocus sativus stigma (5 and 10 µg/rat) into the nucleus accumbens shell part of rats, 5 min before morphine (10 mg/kg) administration, caused a decrease ...
... ethanolic extracts and crocin may have interaction with the opioid system to reduce withdrawal syndrome (Hosseinzadeh H. 2010). Alcohol extract of Crocus sativus stigma (5 and 10 µg/rat) into the nucleus accumbens shell part of rats, 5 min before morphine (10 mg/kg) administration, caused a decrease ...
The Neurocircuitry of Impaired Insight in Drug Addiction
... distributed neural network4. Damage to specific sets of neural circuits may interrupt the internal signals that indicate a problem. Thus, the absence of information about the left side of one's body is no more worrisome than lack of visual information from behind one's head – no impairment is regist ...
... distributed neural network4. Damage to specific sets of neural circuits may interrupt the internal signals that indicate a problem. Thus, the absence of information about the left side of one's body is no more worrisome than lack of visual information from behind one's head – no impairment is regist ...
Synaptic plasticity: taming the beast
... multiplicative properties of synaptic scaling are understood. Direct application of glutamate4 and fluorescent labeling of receptors5, 6 show that synaptic scaling is due to a postsynaptic change in the number of functional glutamate receptors. Furthermore, increasing synaptic strength during reduce ...
... multiplicative properties of synaptic scaling are understood. Direct application of glutamate4 and fluorescent labeling of receptors5, 6 show that synaptic scaling is due to a postsynaptic change in the number of functional glutamate receptors. Furthermore, increasing synaptic strength during reduce ...
An Investigation of Anti-Depressant Activity of
... associated with some limitations and there is an urgent need for alternative medications for these disorders. Despite the widely popular use of CCO for treating nervous disorders, there is an absence of scientific reports about the evaluation of its pharmacological effects. In this work, it was demo ...
... associated with some limitations and there is an urgent need for alternative medications for these disorders. Despite the widely popular use of CCO for treating nervous disorders, there is an absence of scientific reports about the evaluation of its pharmacological effects. In this work, it was demo ...
Nature`s
... ginseng which is dried only •History •Chemistry-ginsenosides, a series of steroid glycosides. The ratio of these differ between Panax sp. ...
... ginseng which is dried only •History •Chemistry-ginsenosides, a series of steroid glycosides. The ratio of these differ between Panax sp. ...
Frog intestinal perfusion to evaluate drug permeability: application to
... involving transporters such as P-gp and CYP3A enzymes. In this study we have developed SPIP using frog as the animal model for the assessment of intestinal permeability of drugs, which are substrates of P-gp, and CYP3A4 in humans. Frog small intestine has the same composition and villi as vertebrate ...
... involving transporters such as P-gp and CYP3A enzymes. In this study we have developed SPIP using frog as the animal model for the assessment of intestinal permeability of drugs, which are substrates of P-gp, and CYP3A4 in humans. Frog small intestine has the same composition and villi as vertebrate ...
Basics Pharmacology Review - Dr. Roland Halil
... (Partially adapted from slides by Marc Riachi, R.Ph.) ...
... (Partially adapted from slides by Marc Riachi, R.Ph.) ...
phytopharmacological aspects of chlorophytum borivilianum
... treatment was continued further in all groups (control group-dist. water and treated group except group with sidenafil citrate 4mg/kg/day) for 60 days. At 125 mg/kg, C. borivilianum group had a marked aphrodisiac action, increased libido, sexual vigor and sexual arousal as compared with other groups ...
... treatment was continued further in all groups (control group-dist. water and treated group except group with sidenafil citrate 4mg/kg/day) for 60 days. At 125 mg/kg, C. borivilianum group had a marked aphrodisiac action, increased libido, sexual vigor and sexual arousal as compared with other groups ...
Sedation during extracorporeal membrane oxygenation—why more
... ambulation in selected patients has been reported5, this is not always possible. This report provides preliminary mechanistic explanation for altered sedation requirements in these patients on ECMO. It also highlights important clinical issues such as sedation targets during ECMO, utility of bispect ...
... ambulation in selected patients has been reported5, this is not always possible. This report provides preliminary mechanistic explanation for altered sedation requirements in these patients on ECMO. It also highlights important clinical issues such as sedation targets during ECMO, utility of bispect ...
memory systems in the brain
... value of taste is represented. This is shown by the fact that when the reward value of the taste of food is decreased by feeding it to satiety, the responses of neurons in the orbitofrontal cortex, but not at earlier stages of processing in primates, decrease to the food as the reward value of the f ...
... value of taste is represented. This is shown by the fact that when the reward value of the taste of food is decreased by feeding it to satiety, the responses of neurons in the orbitofrontal cortex, but not at earlier stages of processing in primates, decrease to the food as the reward value of the f ...
Synaptic Regulation of Action Potential Timing in
... yielding tip resistances of 5– 8 MV. Series resistance (15–30 MV) was monitored throughout the recording, and neurons exhibiting .25% change were rejected. Voltage errors attributable to series resistance and the liquid junction potential were subtracted off-line. In some instances in which the reve ...
... yielding tip resistances of 5– 8 MV. Series resistance (15–30 MV) was monitored throughout the recording, and neurons exhibiting .25% change were rejected. Voltage errors attributable to series resistance and the liquid junction potential were subtracted off-line. In some instances in which the reve ...