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Chemotherapy-Induced Nausea and Vomiting
Chemotherapy-Induced Nausea and Vomiting

... which contains a number of local mediators, such as 5-hydroxytryptamine (5-HT), substance P, and cholecystokinin. Antineoplastic agents, through either direct mucosal or blood-borne mechanisms, stimulate enteroendocrine cells to release mediators, which then bind to the appropriate receptors on the ...
Sleep walking
Sleep walking

... KENNETH PARKS CASE. A 23-year-old married Toronto man, was suffering from severe insomnia caused by joblessness and gambling debts. Early morning, May 23 1987 he arose, got in his car and drove 23 kilometers to his in-laws' home. He stabbed to death his mother-in-law with a carving knife. Parks also ...
Pharmacotherapy Treatment Options for Insomnia
Pharmacotherapy Treatment Options for Insomnia

... α-5 subtypes) [28,29]. This preferential selectivity by non-benzdiazepines and their short half-lives (8 h or less) are probably responsible for the suggested (but still debated) finding of a reduction in next-day fatigue as well as less psychomotor and neuropsychological dysfunction in comparison t ...
Structure and Function of the Brain Serotonin System
Structure and Function of the Brain Serotonin System

... in the major psychoses. This hypothesis was based primarily on the finding that the actions of 5-HT in the periphery were antagonized by the powerful hallucinogenic (or psychotomimetic) drug d-lysergide (d-LSD) ( an extensive review of the relationship between the action of hallucinogenic drugs and ...
Spatial Responsiveness of Monkey Hippocampal Neurons to
Spatial Responsiveness of Monkey Hippocampal Neurons to

... stimuli. Sometimes food (raisin, a piece of apple, cookie, etc.) was given to the monkey to retain its attention to the presented objects. Since, in the experimental situation reported here, the monkey’s limb movements (e.g., reaching his hands to foods) were restricted by attaching an acrylic plate ...
Pain management in sports medicine
Pain management in sports medicine

... agents generally are effective at decreasing pain and allow a quicker return to activity and rehabilitation.12,22–27. However, effects of these agents on joint stability and on joint injuries other than the ankle and shoulder are unknown. In general, the COXIBs are associated with fewer gastrointest ...
TAS-116, a Highly Selective Inhibitor of Heat Shock
TAS-116, a Highly Selective Inhibitor of Heat Shock

... activity while minimizing adverse effects such as visual disturbances that are observed with other compounds of this class. Mol ...
Anatomical Changes in Human Motor Cortex and Motor Pathways
Anatomical Changes in Human Motor Cortex and Motor Pathways

... Using Statistical Parametric Mapping (SPM; Friston et al. 1995), the 3 T1weighted images from each subject were coregistered and averaged. The averaged image was bias corrected using the SPM5 unified segmentation (Ashburner and Friston 2005). The bias-corrected images were segmented and spatially nor ...
The Anterior Midline Field: Coercion or decision making? Brain and
The Anterior Midline Field: Coercion or decision making? Brain and

... a b s t r a c t To study the neural bases of semantic composition in language processing without confounds from syntactic composition, recent magnetoencephalography (MEG) studies have investigated the processing of constructions that exhibit some type of syntax-semantics mismatch. The most studied c ...
Iodine deficiency is single most common cause of mental handicap
Iodine deficiency is single most common cause of mental handicap

... Overview of IDD assessment and indicators H. Delshad M.D Endocrinologist ...
Anorexia nervosa during adolescence and young adulthood
Anorexia nervosa during adolescence and young adulthood

... linkage studies. Typically, candidate gene studies have been performed on particular neurotransmitters of interest, such as dopamine, serotonin and opioids. Neuropeptides, which are substances related to brain development and the neuroendocrine system, have also been also explored. Although Bergen e ...
Full Text  - Cerebral Cortex
Full Text - Cerebral Cortex

... all reward trials but not in no-reward trials. Since the same characteristic activity changes were observed in the ‘Visible food reward’ task (not shown), where actual food or an empty tray was presented as the cue, the differential activity observed in this neuron is not considered to be related t ...
Iboga and Ibogaine - From Forest to Lab
Iboga and Ibogaine - From Forest to Lab

... Antifungal studies Candida albicans ...
In vitro Nanoparticles  Sareh Arjmand, Elham Bidram, Abbas
In vitro Nanoparticles Sareh Arjmand, Elham Bidram, Abbas

... interactions between the protein and polymer. This suggests that the NPs can be used to formulate and deliver the AAT protein as a drug. The main limitation of this process is that the protein is physically bound to the NPs’ surface and as a result, desorption of protein from the NPs’ surface can be ...
Anti-ulcer activity of Ipomoea batatas tubers (sweet potato)
Anti-ulcer activity of Ipomoea batatas tubers (sweet potato)

... Abstract Background: Peptic ulcers occur in that part of the gastrointestinal tract which is exposed to gastric acid and pepsin, i.e., the stomach and duodenum. Gastric and duodenal ulcers are common pathologies that may be induced by a variety of factors such as stress, smoking and noxious agents i ...
Chocolate Consumption Today, people worldwide love sweetened
Chocolate Consumption Today, people worldwide love sweetened

... • The same chemical that is released in your brain when you fall in love. • Phenylethylamine in turn causes the brain to release mesolimbic dopamine in the pleasure centers of the brain, another chemical where its presence is at peak during an orgasm. ...
Mechanisms of excitability in the central and peripheral nervous
Mechanisms of excitability in the central and peripheral nervous

... The vast majority of the synaptic input projects on the dendrites rather than on the soma. One important function of dendrites is therefore to integrate synaptic input, which is influenced by numerous ion channels embedded in the cell membrane. Certain pathological conditions, such as epilepsy and c ...
Rifampicin Antagonizes the Effect of Chloroquine on Chloroquine
Rifampicin Antagonizes the Effect of Chloroquine on Chloroquine

... food vacuole. However, this postulation is unable to explain how verapamil and other reversal agents are able to increase CQ inside the food vacuole and counter resistance. Another factor to consider is the fact that RIF is a known CYP3A4 inducer, which is documented to affect metabolism of quinine ...
J Comp Neurol 2000 Lavenex - University of California, Berkeley
J Comp Neurol 2000 Lavenex - University of California, Berkeley

... the caching season, but did not coincide with either breeding season. In January, caching was completed but squirrels were still dependent on spatial memory to locate their caches; this period coincided with the first breeding season. In June, squirrels had depleted their caches and were not activel ...
Update in Transplantation
Update in Transplantation

...  Multiple effects on proliferating immune cells  Inhibits m-RNA producing IL-2  Negligible effect on pre-sensitized cells  Does not stop ongoing rejection ...
Spontaneous plasticity in the injured spinal cord
Spontaneous plasticity in the injured spinal cord

... raising the possibility that myelin-associated growth inhibitors may not affect all CNS axons equally. Nevertheless, neutralization of myelin-associated inhibitory molecules likely represents what will eventually be an important component of a multi-targeted approach to promote structural reorganiza ...
Drug prescribing pattern of topical corticosteroids
Drug prescribing pattern of topical corticosteroids

... and psoriasis (14%). The most common topical corticosteroid prescribed was clobetasol propionate (60%). Many of the topical corticosteroids were prescribed in fixed dose combination (42%). Majority of the topical corticosteroids prescribed were of very potent (73%) and potent (14%). Average drug per ...
Drugs Used In Pregnancy
Drugs Used In Pregnancy

... Bipolar illness ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)

... Prevalence and Pattern of Self-medication with pain killers The most commonly used analgesic among the students was paracetamol. This is similar to other studies [7,8]. Ibuprofen, aspirin and diclofenac were also used but not as frequently as paracetamol. The frequent use of paracetamol may be assoc ...
The Brain and Nervous Systems
The Brain and Nervous Systems

... brain do exist. However: • Many supposed differences are stereotypes. • May not produce a difference in behavior or performance. • Do not account for differences in behavior across situations. • Some differences can be the result rather than the cause of behavioral differences. • Results of studies ...
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Neuropsychopharmacology

Neuropsychopharmacology, an interdisciplinary science related to psychopharmacology (how drugs affect the mind) and fundamental neuroscience, is the study of the neural mechanisms that drugs act upon to influence behavior. It entails research of mechanisms of neuropathology, pharmacodynamics (drug action), psychiatric illness, and states of consciousness. These studies are instigated at the detailed level involving neurotransmission/receptor activity, bio-chemical processes, and neural circuitry. Neuropsychopharmacology supersedes psychopharmacology in the areas of ""how"" and ""why"", and additionally addresses other issues of brain function. Accordingly, the clinical aspect of the field includes psychiatric (psychoactive) as well as neurologic (non-psychoactive) pharmacology-based treatments.Developments in neuropsychopharmacology may directly impact the studies of anxiety disorders, affective disorders, psychotic disorders, degenerative disorders, eating behavior, and sleep behavior.The way fundamental processes of the brain are being discovered is creating a field on par with other “hard sciences” such as chemistry, biology, and physics, so that eventually it may be possible to repair mental illness with ultimate precision. An analogy can be drawn between the brain and an electronic device: neuropsychopharmacology is tantamount to revealing not only the schematic diagram, but the individual components, and every principle of their operation. The bank of amassed detail and complexity involved is huge; mere samples of some of the details are given in this article.
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