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proteins
proteins

... resulting from its specific molecular order. • Three levels of structure: primary, secondary, and tertiary structure, are used to organize the folding within a single polypeptide. • Quarternary structure arises when two or more polypeptides join to form a protein. ...
DNA/RNA
DNA/RNA

... Recombinant DNA- Genetically engineered DNA prepared by splicing genes from one species into the cells of a different species. Such DNA becomes part of the host's genetic makeup and is ...
three possibile models for replication
three possibile models for replication

... During transcription, we also read the template DNA strand from its 3’ end towards its 5’ end. This means we build the complementary single-stranded mRNA molecule from its 5’ end towards its 3’ end. During translation, the ribosome and tRNA molecules read the mRNA strand from its 5’ towards its 3’ e ...
Evolution and multilevel optimization of the genetic code
Evolution and multilevel optimization of the genetic code

... variant codes, but all with minor differences (why? proposal of extensive horizontal gene transfer during early evolution, would lead to optimality and ...
Genetic code ambiguity: an unexpected source of proteome
Genetic code ambiguity: an unexpected source of proteome

... to 5% under stress. C. albicans tolerates up to 28% of leucine misincorporation without visible effects on growth rate, suggesting that CUG ambiguity may fluctuate between 3% and 28%, depending on environmental conditions. Remarkably, CUG ambiguity increases secretion of lipases and proteinases and ...
First Life Forms Roles of RNA
First Life Forms Roles of RNA

... composition ...
Ch 15 - .Gene Regulation
Ch 15 - .Gene Regulation

... [transcription factors- proteins that initiate RNA pol. binding] once a gene is unpackaged it will be transcribed. (transposons shut down genes by interrupting code, gene jumping, also encourages mutations) ...
(a) (b) - My SMCC
(a) (b) - My SMCC

... • RNA is single stranded • contains ribose instead of deoxyribose • contains uracil instead of thymine • there are different types of RNA - all with unique roles ...
Mutations
Mutations

... Causes of Mutations • Mutations are caused by changes in the nucleotide sequence of DNA (A, T, C, G) or of a gene (specific area of a chromosome) • This can occur: – During DNA replication – During cell division – After cell division ...
AMINO ACID DEGRADATION
AMINO ACID DEGRADATION

... acetyl CoA are called KETOGENIC AMINO ACIDS because they can be converted into ketone bodies. The amino acids that are converted in the remaining of the seven molecules are called GLUCOGENIC AMINO ACIDS becaause they can be converted into phosphoenol pyruvate and then in glucose. • Some amino acids ...
Biocatalysis in Organic Synthesis
Biocatalysis in Organic Synthesis

... Enzymes display three major types of selectivities: ...
Directions for Dog Breed Genetics
Directions for Dog Breed Genetics

... The purpose of this activity is to have fun while learning one of biology’s central dogmas: how DNA is transcribed into mRNA which is then translated into an amino acid sequence that makes up a specific protein. The domesticated dog (Canis familiaris) is an interesting species to study because it is ...
Dangerously Thin: A case study on the Genetic Code
Dangerously Thin: A case study on the Genetic Code

... Henry had planned to do some traveling, Dr. Strickland opened with a question that Henry initially found to be a bit out of the ordinary. “Any chance this swelling showed up after a long flight?” “As a matter of fact it did,” Henry replied. “My gut tells me that you may have a clot in that leg, but ...
Chapter 3: Biochemistry
Chapter 3: Biochemistry

... 5. Hydrolysis: using water to break the bonds of complex molecules 6. ATP (adenosine triphosphate): compound with a large amount of energy a) covalent bond breaks and energy is released b) energy is used by the cell to drive chemical ...
Exam Name___________________________________
Exam Name___________________________________

... 8) Which of the following statements regarding methyl- -L-glucopyranoside is correct? A) This glycoside will be hydrolyzed to the cyclic hemiacetal in dilute aqueous acid. B) This glycoside will undergo no reaction when treated with excess CH3 I/Ag2 O. C) This glycoside undergoes mutorotation in aqu ...
student worksheet
student worksheet

... a good description? Why or why not? In living things, the detailed directions for cells to make the proteins that control and compose the organism must be very precise. The code found in DNA is the basis for forming proteins. In this activity you will see how the proteins are formed through an amazi ...
Protein And Amino Acids - Manasquan Public Schools
Protein And Amino Acids - Manasquan Public Schools

...  Can determine how well children grow and how well adults maintain health  Limiting amino acid- the essential amino acid found in the shortest supply relative to the amounts needed for protein synthesis in the body. The four most likely to be limiting: lysine, methionine, threonine, and tryptophan ...
Genetic Mutation Worksheet
Genetic Mutation Worksheet

... 5. You have a DNA sequence that codes for a protein and is 105 nucleotides long. A frameshift mutation occurs at the 85th base- how many amino acids will be correct in this protein? 6. Given the following three mRNA sequences, TWO code for the same protein. Which two? #1. AGU UUA GCA ACG AGA UCA #2 ...
large molecule consisting of many identical or similar subunits
large molecule consisting of many identical or similar subunits

... side groups (R-chains) and ionic bonds between charged side chains. Hydrophobic regions interact and stay away from water as well. Sulfur components of proteins form disulfide bridges. quaternary (4) structure: interaction among several polypeptide chains within a single protein. ...
Chapters 2
Chapters 2

... Proteins-large complex molecules are major building blocks of all living organisms. Discuss the following in relation to proteins: a. The chemical composition and levels of structures of proteins b. The roles of DNA and RNA in protein synthesis c. The role of proteins in regulating chemical reaction ...
Assessment Schedule – 2007 Biology: Describe the role of DNA in
Assessment Schedule – 2007 Biology: Describe the role of DNA in

... base of the codon has been changed from an A to a U BOTH needed. 2(c) Describes the effect on structure and function, eg: • Produces a different mRNA codon, changing the shape of the protein by substituting a different amino acid. This may change the protein’s function by changing how it interacts w ...
HOW TO FIND GENES WITHIN A DNA SEQUENCE?
HOW TO FIND GENES WITHIN A DNA SEQUENCE?

... Scan for ORFs (open reading frames) - check all 6 reading frames (both strands) ...
1. Bacterial genomes
1. Bacterial genomes

... Scan for ORFs (open reading frames) - check all 6 reading frames (both strands) ...
Cut and Paste Macromolecule Instructions
Cut and Paste Macromolecule Instructions

... glucoses together by cutting off and -H- from one molecule and an -OH- from another and taping the 2 molecules together forming a glyosidic bond. Give your disaccharide a name, bearing in mind that sugar names end in “-ose” (glucose, fructose) and write that name on the bottom of the molecule. 3. Th ...
Chapter 5 - glenbrook s hs
Chapter 5 - glenbrook s hs

... Proteins • Importance: instrumental in nearly everything organisms do; 50% dry weight of cells; most structurally sophisticated molecules known ...
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Genetic code



The genetic code is the set of rules by which information encoded within genetic material (DNA or mRNA sequences) is translated into proteins by living cells. Biological decoding is accomplished by the ribosome, which links amino acids in an order specified by mRNA, using transfer RNA (tRNA) molecules to carry amino acids and to read the mRNA three nucleotides at a time. The genetic code is highly similar among all organisms and can be expressed in a simple table with 64 entries.The code defines how sequences of these nucleotide triplets, called codons, specify which amino acid will be added next during protein synthesis. With some exceptions, a three-nucleotide codon in a nucleic acid sequence specifies a single amino acid. Because the vast majority of genes are encoded with exactly the same code (see the RNA codon table), this particular code is often referred to as the canonical or standard genetic code, or simply the genetic code, though in fact some variant codes have evolved. For example, protein synthesis in human mitochondria relies on a genetic code that differs from the standard genetic code.While the genetic code determines the protein sequence for a given coding region, other genomic regions can influence when and where these proteins are produced.
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