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Basic genetics
Basic genetics

... of differential splicing. This results in the potential to produce multiple different proteins from the same gene, adding greatly to the diversity of proteins encoded in the genome. Specific exons may correspond with particular functional domains of proteins, leading to the production of multiple prote ...
as a PDF
as a PDF

... normally imparts polarity to most or all characters. It is, however, important to distinguish between ancient and primitive organisms. Organisms located near the root of universal rRNA-based trees are cladistically ancient, but they are not endowed with a primitive molecular genetic apparatus, nor d ...
Macromolecule worksheet answer Key
Macromolecule worksheet answer Key

... contain carbon, hydrogen, oxygen, nitrogen, and phosphorus (CHON P). Nucleic acids carry the genetic information in a cell. DNA or deoxyribose nucleic acid contains all the instructions for making every protein needed by a living thing. RNA copies and transfers this genetic information so that prote ...
Replication - UniMAP Portal
Replication - UniMAP Portal

... Ile ...
Ch 18
Ch 18

... acetoacetate by a pathway whose first two  steps are identical to those of valine  degradation (Figure 18‐11). The third step is  the same as the first step of fatty acid  oxidation. The fourth step involves an ATP‐ dependent carboxylation, the fifth step is a  hydration, and the last step is a clea ...
They do NOT like water!
They do NOT like water!

... Amino acids are joined by dehydration; the resulting covalent bond is called a peptide bond. • Polymers of amino acids are called polypeptides. ...
slib Human Biochemistry
slib Human Biochemistry

... • Tertiary structure refers to twisting, folding, and coiling of protein chain due to interactions between R groups – Compact structure known as conformation – Most stable – H-bonds – Hydrophobic interactions – Ionic bond between R groups – Disulfide bridge ...
Evidence of Evolution
Evidence of Evolution

... of rock. Younger fossils are found in superficial layers of rock. • Carbon dating can be used to determine the age of a fossil. ...
Molecular Genetics
Molecular Genetics

... 3nucleotide ‘words’ called Codons • RNA Code uses A, C, G, but ‘U’ (uracil) replaces ‘T’ ...
Medical Biochemistry at a Glance. 3rd Edition. At a Glance Brochure
Medical Biochemistry at a Glance. 3rd Edition. At a Glance Brochure

... Medical Biochemistry at a Glance is intended for students of medicine and the biomedical sciences such as nutrition, biochemistry, sports science, medical laboratory sciences, physiotherapy, pharmacy, physiology, pharmacology, genetics and veterinary science. It also provides a succinct review and r ...
Genetic Engineering Pros and Cons
Genetic Engineering Pros and Cons

... Genetic modifications in humans may not be safe now or for the human race in the future. It may fix one disease or mutation and cause other diseases or mutations that could make the person sicker or even kill them. There could be long term affects to the human race that we won’t know about for many ...
molecular biology review sheet
molecular biology review sheet

... Section 2 – Nucleic acids store information in their sequences of chemical units. Section 3 – DNA replication is the molecular mechanism of inheritance. Section 4 – A gene provides the information for making a specific protein. Section 5 – There are two main steps from gene to protein. Section 6 – M ...
Cell and Cell Metabolism Quiz
Cell and Cell Metabolism Quiz

... It allows some substances to pass through and keeps others out. It is selective about what enters but will allow everything to leave the cell. ...
CHAPTER 2 OBJECTIVE EXERCISE
CHAPTER 2 OBJECTIVE EXERCISE

... 29. Describe the levels of structural organization of a protein and explain the significance of a protein's conformation on its overall function. Primary (1o) = sequence of amino acids; Secondary (2o) = twisting of amino acid chain; due to hydrogen bonding; Tertiary (3o) = folding of the amino acid ...
Mutation - TeacherWeb
Mutation - TeacherWeb

... Original DNA: TACGCATGGAAA DNA with Insertion mutation: TACAGCATGGAAA o What is the RNA sequence? o What is the Amino Acid sequence? o How is this AA sequence different from the one above? ...
Unit 6 Student Notes - Flushing Community Schools
Unit 6 Student Notes - Flushing Community Schools

...  Clone = an organism that is  In plants, scientists grow new plants from cuttings (small parts of  In animals, scientists remove an egg, replace the  This process takes three different  This is controversial, since removing the nucleus can be  Genetic Engineering  Genetic engineering = genes ...
Chapter 5 – The Structure and Function of Macromolecules
Chapter 5 – The Structure and Function of Macromolecules

... direct hydrolysis of specific polymers. The resulting monomers are absorbed by the cells lining the gut and transported to the bloodstream for distribution to body cells. ...
Mutations
Mutations

... – Missense mutation- changes one amino acid in polypeptide chain – Nonsense mutation- creates a stop codon in the middle of the polypeptide chain – Splice site mutations- alters the splicing of the pre-mRNA ...
Criteria for gene mutations to be used in genetic testing of Malignant
Criteria for gene mutations to be used in genetic testing of Malignant

... In myotubes (Brinkmeier et al. 1999, Wehner et al. 2002), in microsomal SR preparations from muscle biopsies (Richter et al. 1997), and in lymphoblasts (Girard et al. 2001, Tilgen et al. 2001). Read-out parameters were Ca2+ flux and resting [Ca2+] or ryanodine binding to SRRYR1 preparations. Myotube ...
1 From Lewontin, The Triple Helix IV. Directions in the Study of
1 From Lewontin, The Triple Helix IV. Directions in the Study of

... its function. Yet that understanding does not enter in an integral way into biological explanation. The full explanation of the path between gene and organism needs to include known phenomena that influence the way in which the string of amino acids coded by the gene becomes a protein, that is, a fo ...
P10
P10

... describe how the alteration in the amino acid sequence are generated. – exceptions to this rule can arise, for example, from splice site mutations that lead to missplicing of an exon. The exon may be excluded from the mRNA, generating either an in-frame deletion of the protein sequence or causing a ...
Primary structure: the sequence of amino acids in a polypeptide chain
Primary structure: the sequence of amino acids in a polypeptide chain

... same plane – N-H groups of peptide bonds point in the same direction, roughly parallel to the axis of the helix – C=O groups of peptide bonds point in the opposite direction, also roughly parallel to the axis of the helix – the C=O group of each peptide bond is hydrogen bonded to the N-H group of th ...
Null hypotheses in evolutionary biology
Null hypotheses in evolutionary biology

... protein and DNA sequences among individuals and species are difficult to reconcile with mutation-selection equilibrium (Ch 5.4) Most mutations affecting fitness are deleterious, hence quickly eliminated by selection Ergo: Essentially all new mutations eventually fixed are neutral, and evolve only by ...
Molecular Genetics
Molecular Genetics

... The composition of the DNA is the same in all cells within an organism • Variation among different cells is achieved by reading the DNA differently ...
heartsprotein.easy.pdf
heartsprotein.easy.pdf

... Compare your two pieces of origami paper. An unfolded protein is a long chain of amino acids and is represented by the unfolded piece of origami paper. Do your two pieces of origami paper look the same or different? They should look basically the same, color may differ Do you think that two unfolded ...
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Genetic code



The genetic code is the set of rules by which information encoded within genetic material (DNA or mRNA sequences) is translated into proteins by living cells. Biological decoding is accomplished by the ribosome, which links amino acids in an order specified by mRNA, using transfer RNA (tRNA) molecules to carry amino acids and to read the mRNA three nucleotides at a time. The genetic code is highly similar among all organisms and can be expressed in a simple table with 64 entries.The code defines how sequences of these nucleotide triplets, called codons, specify which amino acid will be added next during protein synthesis. With some exceptions, a three-nucleotide codon in a nucleic acid sequence specifies a single amino acid. Because the vast majority of genes are encoded with exactly the same code (see the RNA codon table), this particular code is often referred to as the canonical or standard genetic code, or simply the genetic code, though in fact some variant codes have evolved. For example, protein synthesis in human mitochondria relies on a genetic code that differs from the standard genetic code.While the genetic code determines the protein sequence for a given coding region, other genomic regions can influence when and where these proteins are produced.
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