Control of human β-globin mRNA stability and its impact on beta
... Human α- and b-globin genes descend from a common ancestral gene, share general and specific structural features, and both encode extraordinarily stable mRNAs in erythroid cells, which allow co-expression of α- and bglobin proteins to reach high levels. Human globin gene expression is a highly regul ...
... Human α- and b-globin genes descend from a common ancestral gene, share general and specific structural features, and both encode extraordinarily stable mRNAs in erythroid cells, which allow co-expression of α- and bglobin proteins to reach high levels. Human globin gene expression is a highly regul ...
Essentials of PHYSIOLOGICAL CHEMISTRY
... is filled with a jellylike, viscous substance called protoplasm, which is fundamentally the same whether it is found in animal or plant cells. Protoplasm is the basic substance concerned with life. Biochemistry then becomes the study of the composition of protoplasm and the chemical changes which ta ...
... is filled with a jellylike, viscous substance called protoplasm, which is fundamentally the same whether it is found in animal or plant cells. Protoplasm is the basic substance concerned with life. Biochemistry then becomes the study of the composition of protoplasm and the chemical changes which ta ...
A defined subset of adenylyl cyclases is regulated by bicarbonate ion.
... specific activity demonstrating that HCO3- activation of cyaB1595-859 was independent of the associated cation. The catalytic activity of cyaB1595-859 was also measured in the presence of a number of anions with Na+ as cation (Figure 1C). Anions structurally distinct from HCO3- (e.g. Cl-, NO3-, and ...
... specific activity demonstrating that HCO3- activation of cyaB1595-859 was independent of the associated cation. The catalytic activity of cyaB1595-859 was also measured in the presence of a number of anions with Na+ as cation (Figure 1C). Anions structurally distinct from HCO3- (e.g. Cl-, NO3-, and ...
Poster
... Colorblindness, a genetic disorder affecting millions of people worldwide, is caused by mutations in a retinal protein, opsin. Opsin is a G-protein coupled receptor which binds to light sensitive retinal. When light enters the cell, the retinal isomerizes from the cis form to the trans form, and ops ...
... Colorblindness, a genetic disorder affecting millions of people worldwide, is caused by mutations in a retinal protein, opsin. Opsin is a G-protein coupled receptor which binds to light sensitive retinal. When light enters the cell, the retinal isomerizes from the cis form to the trans form, and ops ...
Biochemical but not clinical vitamin A deficiency results from
... concentrations were normal in both siblings and their mother. TTR gene analysis A missense mutation of the TTR gene [transition of amino acid 84 in exon 3 from isoleucine (ATC) to asparagine (AAC) (Ile84→Asn)] has been described (22) and RBP plasma concentrations were reported to be substantially re ...
... concentrations were normal in both siblings and their mother. TTR gene analysis A missense mutation of the TTR gene [transition of amino acid 84 in exon 3 from isoleucine (ATC) to asparagine (AAC) (Ile84→Asn)] has been described (22) and RBP plasma concentrations were reported to be substantially re ...
The Frequency Distribution of Nucleotide Variation in Drosophila
... 0.11). This dependence of the statistical results on period data could be indicative of locus effects or could be attributable to reduced power associated with removal of a large amount of data from the analysis. The conclusion of roughly equal numbers of preferred and unpreferred fixations is based ...
... 0.11). This dependence of the statistical results on period data could be indicative of locus effects or could be attributable to reduced power associated with removal of a large amount of data from the analysis. The conclusion of roughly equal numbers of preferred and unpreferred fixations is based ...
Annotation Strategy Guide - GEP Community Server
... Selecting a better supported splice site: While extension of an open reading frame is important for conserving the length of the coding exon, it is also important to consider selecting the best-supported splice site. For example, let’s look at the first coding exon (1_2365_0) of Dyrk3 in D. mojave ...
... Selecting a better supported splice site: While extension of an open reading frame is important for conserving the length of the coding exon, it is also important to consider selecting the best-supported splice site. For example, let’s look at the first coding exon (1_2365_0) of Dyrk3 in D. mojave ...
Biomolecules
... – The type of bonds between monosaccharides determines their relative orientation in a carbohydrate which determines the secondary structure of the carbohydrate. ...
... – The type of bonds between monosaccharides determines their relative orientation in a carbohydrate which determines the secondary structure of the carbohydrate. ...
Presence of Escherichia coli carrying the EAST1 toxin gene in farm
... cated heterogeneity in the DNA sequences between E. coli isolated from humans and those from animals. As part of a study on the prevalence of AIDA-I (adhesion involved in diffuse adherence) among pigs with postweaning diarrhea or edema disease, Ha et al. [15], observed that of the 45 AIDA-I-positive ...
... cated heterogeneity in the DNA sequences between E. coli isolated from humans and those from animals. As part of a study on the prevalence of AIDA-I (adhesion involved in diffuse adherence) among pigs with postweaning diarrhea or edema disease, Ha et al. [15], observed that of the 45 AIDA-I-positive ...
mtr function Background Luis M. Corrochano
... The product of the mtr gene is an amino acid permease required for the uptake of neutral aliphatic, and aromatic amino acids, like tryptophan (Koo and Stuart 1991, Dillon and Stadler 1994). In addition, the MTR permease allows the entry of toxic amino acid analogs, like p-fluorophenylalanine (FPA) o ...
... The product of the mtr gene is an amino acid permease required for the uptake of neutral aliphatic, and aromatic amino acids, like tryptophan (Koo and Stuart 1991, Dillon and Stadler 1994). In addition, the MTR permease allows the entry of toxic amino acid analogs, like p-fluorophenylalanine (FPA) o ...
practice test - WordPress.com
... d. clarifies confusion produced by tremendous variation. e. all of these Hereditary instructions must a. be unchanging most of the time. b. pass from one generation to the next. c. control a large number of different characteristics. d. provide for the rare change in instructions. e. all of these Wh ...
... d. clarifies confusion produced by tremendous variation. e. all of these Hereditary instructions must a. be unchanging most of the time. b. pass from one generation to the next. c. control a large number of different characteristics. d. provide for the rare change in instructions. e. all of these Wh ...
PierceEtAl2004BioBull - Region 11 Math And Science Teacher
... composed of an acellular, fibrous network reminiscent of the collagen fiber network in whale blubber. Amino acid analyses of an acid hydrolysateindicatedthat the fibers are composed of 31% glycine residues and also contain hydroxyprolineand hydroxylysine, all diagnostic of collagen. Using primersdes ...
... composed of an acellular, fibrous network reminiscent of the collagen fiber network in whale blubber. Amino acid analyses of an acid hydrolysateindicatedthat the fibers are composed of 31% glycine residues and also contain hydroxyprolineand hydroxylysine, all diagnostic of collagen. Using primersdes ...
Detection and Estimation of Collagen
... In 1970 Mitchell and Taylor13 critically examined the available methods and concluded that no single method could combine accuracy with freedom from errors caused by interferring substances. Consequently, several different experimental approaches can be found in the literature, depending upon the na ...
... In 1970 Mitchell and Taylor13 critically examined the available methods and concluded that no single method could combine accuracy with freedom from errors caused by interferring substances. Consequently, several different experimental approaches can be found in the literature, depending upon the na ...
Hydrogen sul de production by yeast during alcoholic fermentation
... yeast strains: a high sulfite-producing strain (JN10) and a low sulfite-producing strain (JN17)29. QTL is a genome-wide, linkage analysis tool that allows researchers to dissect the contribution and interaction of different genes to complex multi-genic traits, such as sulfide production. In this way ...
... yeast strains: a high sulfite-producing strain (JN10) and a low sulfite-producing strain (JN17)29. QTL is a genome-wide, linkage analysis tool that allows researchers to dissect the contribution and interaction of different genes to complex multi-genic traits, such as sulfide production. In this way ...
alpha-amylase from bacillus licheniformis
... substances. The formulated α-amylase is referred to below as the α-amylase preparation. The α-amylase preparation is currently marketed under a trade name Liquozyme X. The manufacturer of these products, Novozymes A/S, submitted a dossier to JECFA containing detailed information about the α-amylase ...
... substances. The formulated α-amylase is referred to below as the α-amylase preparation. The α-amylase preparation is currently marketed under a trade name Liquozyme X. The manufacturer of these products, Novozymes A/S, submitted a dossier to JECFA containing detailed information about the α-amylase ...
- Wiley Online Library
... sequence data indicate that the genes encoding carotenoid enzymes are under relaxed selective constraints and are accumulating deleterious mutations (Fig. 1d; Table S1). Indeed, three of the seven recovered transcripts contained premature stop codons (Fig. 1c) and six contained one or more large (> ...
... sequence data indicate that the genes encoding carotenoid enzymes are under relaxed selective constraints and are accumulating deleterious mutations (Fig. 1d; Table S1). Indeed, three of the seven recovered transcripts contained premature stop codons (Fig. 1c) and six contained one or more large (> ...
Oxalate decarboxylase of the white-rot fungus
... bacteria and fungi. In wood-decaying fungi the enzyme has been linked to the regulation of intraand extracellular quantities of oxalic acid, which is one of the key components in biological decomposition of wood. ODC enzymes are biotechnologically interesting for their potential in diagnostics, agri ...
... bacteria and fungi. In wood-decaying fungi the enzyme has been linked to the regulation of intraand extracellular quantities of oxalic acid, which is one of the key components in biological decomposition of wood. ODC enzymes are biotechnologically interesting for their potential in diagnostics, agri ...
fulltext - DiVA portal
... Background: Analysis of the Escherichia coli collection of reference strains (ECOR) for the presence of the gene locus clyA, which encodes the pore-forming protein ClyA (cytolysin A), revealed that a non-functional clyA locus is common among certain extraintestinal pathogenic E. coli (ExPEC). In fac ...
... Background: Analysis of the Escherichia coli collection of reference strains (ECOR) for the presence of the gene locus clyA, which encodes the pore-forming protein ClyA (cytolysin A), revealed that a non-functional clyA locus is common among certain extraintestinal pathogenic E. coli (ExPEC). In fac ...
Full-Text PDF
... spectra of PHA polymers synthesized by P. putida LS46123 were acquired by dissolving 10 mg of each polymer in deuterochloroform (CDCl3 ) and analyzed on a Brucker AMX-300 spectrometer (Brucker Biospin AG, Billerica, MA, USA) at 22 ◦ C with 7.4 ms pulse width (30◦ pulse angle), 1 s pulse repetition, ...
... spectra of PHA polymers synthesized by P. putida LS46123 were acquired by dissolving 10 mg of each polymer in deuterochloroform (CDCl3 ) and analyzed on a Brucker AMX-300 spectrometer (Brucker Biospin AG, Billerica, MA, USA) at 22 ◦ C with 7.4 ms pulse width (30◦ pulse angle), 1 s pulse repetition, ...
Evolution, structure and function of mitochondrial carriers: a
... (Palmieri et al., 2006 and references in this work), a third in H. sapiens (Palmieri, 2004 and references in this work) and a quarter in A. thaliana (Picault et al., 2004 and references in this work) were identified. Table 1 lists the main subfamilies into which MCs can be divided according to their ...
... (Palmieri et al., 2006 and references in this work), a third in H. sapiens (Palmieri, 2004 and references in this work) and a quarter in A. thaliana (Picault et al., 2004 and references in this work) were identified. Table 1 lists the main subfamilies into which MCs can be divided according to their ...
THE COLLAGENS
... Nearly one residue out of three is Gly Proline content is unusually high Unusual amino acids found: ◦ 4-hydroxyproline ◦ 3-hydroxyproline ◦ 5-hydroxylysine ◦ Pro and HyPro together make 30% of res. ...
... Nearly one residue out of three is Gly Proline content is unusually high Unusual amino acids found: ◦ 4-hydroxyproline ◦ 3-hydroxyproline ◦ 5-hydroxylysine ◦ Pro and HyPro together make 30% of res. ...
Eds., M. Kawaguchi, K. Misaki, H. Sato, T. Yokokawa, T.... and S. Tanabe, pp. 35–40.
... Fig. 1. Schematic illustration of the effect of taurine for protecting germ cell from oxidative stress by promoting Cu/Zn SOD expression. O 2–, reactive oxygen species. ...
... Fig. 1. Schematic illustration of the effect of taurine for protecting germ cell from oxidative stress by promoting Cu/Zn SOD expression. O 2–, reactive oxygen species. ...
High-resolution melting analysis of the single nucleotide
... The HRM CP 8, characteristic of PCR sequence-type 9 (S475S+F481F+D492D+T501T+A508A+G510G+T539T+ K556K+S575A), was generated by the presence of six out of nine SNPs located within the 151 bp HRM amplicon (Tables 1, 2), which displayed a unique melting curve shape in the difference plot. Furthermore, ...
... The HRM CP 8, characteristic of PCR sequence-type 9 (S475S+F481F+D492D+T501T+A508A+G510G+T539T+ K556K+S575A), was generated by the presence of six out of nine SNPs located within the 151 bp HRM amplicon (Tables 1, 2), which displayed a unique melting curve shape in the difference plot. Furthermore, ...
... products from our artificial polyproteins are not produced by proteolysis. We propose that the FMDV 2A sequence, rather than representing a proteolytic element, modifies the activity of the ribosome to promote hydrolysis of the peptidyl(2A)-tRNAGly ester linkage, thereby releasing the polypeptide fr ...
Expanded genetic code
An expanded genetic code is an artificially modified genetic code in which one or more specific codons have been re-allocated to encode an amino acid that is not among the 22 encoded proteinogenic amino acids.The key prerequisites to expand the genetic code are: the non-standard amino acid to encode, an unused codon to adopt, a tRNA that recognises this codon, and a tRNA synthase that recognises only that tRNA and only the non-standard amino acid.Expanding the genetic code is an area of research of synthetic biology, an applied biological discipline whose goal is to engineer living systems for useful purposes. The genetic code expansion enriches the repertoire of useful tools available to science.