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Set 6 Immune System and Vaccines
Set 6 Immune System and Vaccines

... that enter your body and are perceived as a threat by your adaptive immune system. One way that it responds is to produce defence proteins called “antibodies”. ...
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...  defense responses that do not distinguish between one threat and another  are present at birth  include: physical barriers (e.g. skin), phagocytic cells (neutrophils, monocytes, macrophages, eosinophils), chemicals (complement system), inflammation, fevers, etc.  provides body with “non-specifi ...
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... Antigens have specific regions where antibodies bind to them • Antigens are usually molecules on the surface of viruses or foreign cells • Antigenic determinants are the specific regions on an antigen to which antibodies bind –Antigens may have several different determinants –Immune system may dire ...
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... All cells need things. They have binding sites on the cell surface to bind with whatever it needs; then a channel opens up, takes it in and then the channel is closed again. Viruses – Bind to a cell. To do this they must have a 'key' and achieve this by having a site that binds with the surface bind ...
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... 21. B cells (memory, plasma), T cells (helper, CTL, memory), humoral immunity, cellular immunity 22. It can fight a variety of pathogens 23. swelling, redness, pain 24. tissue damage caused by phagocytes, macrophages 25. phagocytes, macrophages 26. Denatures pathogens enzymes 27. mucus 28. enzymes 2 ...
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... • Maturation requires three sequential signals. – Antigen-specific signal is transmitted by the TCR upon recognition of peptide:Class I antigen presented by a professional antigen presenting cell (licensed antigenpresenting cell) or by a tissue cell. – Costimulatory signal is transmitted by CD28:B7 ...
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T cell



T cells or T lymphocytes are a type of lymphocyte (in turn, a type of white blood cell) that plays a central role in cell-mediated immunity. They can be distinguished from other lymphocytes, such as B cells and natural killer cells (NK cells), by the presence of a T-cell receptor (TCR) on the cell surface. They are called T cells because they mature in the thymus (although some also mature in the tonsils). The several subsets of T cells each have a distinct function. The majority of human T cells rearrange their alpha/beta T cell receptors and are termed alpha beta T cells and are part of adaptive immune system. Specialized gamma delta T cells, which comprise a minority of T cells in the human body (more frequent in ruminants), have invariant TCR (with limited diversity), can effectively present antigens to other T cells and are considered to be part of the innate immune system.
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