See presentation #4
... • Multipotent stem cells originally defined in the bone marrow • Equivalent to stromal cells identified back in the 1960’s by Dexter and colleagues • Grown from BM mononuclear cells by their adherence to plastic in tissue culture flasks ...
... • Multipotent stem cells originally defined in the bone marrow • Equivalent to stromal cells identified back in the 1960’s by Dexter and colleagues • Grown from BM mononuclear cells by their adherence to plastic in tissue culture flasks ...
Specific Immunity - Truro School Moodle
... • They do not directly produce antibodies but circulate in the plama and tissue fluid. • When they encounter the same antigen later they can divide rapidly and clone to produce more plasma and memory cells. • Plasma cells then produce lots of anti bodies very quickly. • Provide long term immunity ...
... • They do not directly produce antibodies but circulate in the plama and tissue fluid. • When they encounter the same antigen later they can divide rapidly and clone to produce more plasma and memory cells. • Plasma cells then produce lots of anti bodies very quickly. • Provide long term immunity ...
Humoral Immunity
... specific immune response. • A group of cells called Antigen presenting cells (APC) activate the acquired immune system. • Macrophages, Dendritic cells and B-cells are ...
... specific immune response. • A group of cells called Antigen presenting cells (APC) activate the acquired immune system. • Macrophages, Dendritic cells and B-cells are ...
Prospective analysis of dendritic cell (DC) therapy in cancer patients`.
... by the late Professor Ralph Steinmen( picture Nobel Prize in Medicine 2011 ) in the late 1980 dendritic cells are now found to have essential roles in cancer therrapy Dendritic cells recognize the antigen feedback and respond by producing specific antigenic peptides (representation) on their surface ...
... by the late Professor Ralph Steinmen( picture Nobel Prize in Medicine 2011 ) in the late 1980 dendritic cells are now found to have essential roles in cancer therrapy Dendritic cells recognize the antigen feedback and respond by producing specific antigenic peptides (representation) on their surface ...
- ISpatula
... 2.Fatty change is manifested by the appearance of lipid vacuoles in the cytoplasm. These changes are seen in cells involved in fat metabolism as hepatocytes and myocardial cells. ...
... 2.Fatty change is manifested by the appearance of lipid vacuoles in the cytoplasm. These changes are seen in cells involved in fat metabolism as hepatocytes and myocardial cells. ...
student notes
... Transfusion with incompatible blood leads to destruction of the transfused cells and life -threatening situation for the patients. Antibodies to nonself blood antigens already exist in the body. MHC molecules are responsible for stimulating the __________________________of tissue grafts and organ tr ...
... Transfusion with incompatible blood leads to destruction of the transfused cells and life -threatening situation for the patients. Antibodies to nonself blood antigens already exist in the body. MHC molecules are responsible for stimulating the __________________________of tissue grafts and organ tr ...
common homwework mistakes
... virus cause antigenic variability. Explain how antigenic variability has caused some people to become infected more than once with influenza viruses. (2 marks) The B cells for the old influenza virus do not recognise the new antigens. Scores 1 out of 2 marks. Why? Markscheme: memory B / T cells do n ...
... virus cause antigenic variability. Explain how antigenic variability has caused some people to become infected more than once with influenza viruses. (2 marks) The B cells for the old influenza virus do not recognise the new antigens. Scores 1 out of 2 marks. Why? Markscheme: memory B / T cells do n ...
The Immune System and Allergy
... • Differ from B cell receptors only in the constant (C) region of the heavy chain • The five major types of heavy chain constant regions determine the five major classes of antibodies (M, G, A, E, and D) • Changes in the heavy chain gene that switch B cells from producing one antibody class to anoth ...
... • Differ from B cell receptors only in the constant (C) region of the heavy chain • The five major types of heavy chain constant regions determine the five major classes of antibodies (M, G, A, E, and D) • Changes in the heavy chain gene that switch B cells from producing one antibody class to anoth ...
Immunity
... target cell and granzymes enter the virus infected cell causing apoptosis or programmed cell death The cytotoxic proteins only affect those cells to which the Tc cell has specifically interacted ...
... target cell and granzymes enter the virus infected cell causing apoptosis or programmed cell death The cytotoxic proteins only affect those cells to which the Tc cell has specifically interacted ...
Tissue effector memory T cells Lymphoid central memory T cells
... and stays constant over many years The number of memory T-cells also stays constant over decades ...
... and stays constant over many years The number of memory T-cells also stays constant over decades ...
histology of lymphoid organs lymphoid organs
... EPO TPO etc EPO, etc. • Cytokines are a unique family of growth factors Æ messenger molecules that can communicate signals from one cell type to another – Secreted primarily from leukocytes but also produced by various cells of the body Æ interleukin (IL) – IL instruct the receiving cells to prolife ...
... EPO TPO etc EPO, etc. • Cytokines are a unique family of growth factors Æ messenger molecules that can communicate signals from one cell type to another – Secreted primarily from leukocytes but also produced by various cells of the body Æ interleukin (IL) – IL instruct the receiving cells to prolife ...
Vertebrate Innate Immunity
... repertoire of B cells in a lymph node, each with its own specific type of antigen receptor embedded in its surface. The cells’ receptors are in place before they ever encounter an antigen 2. The first time an antigen enters the body and is swept into a lymph node, antigenic determinants on its surfa ...
... repertoire of B cells in a lymph node, each with its own specific type of antigen receptor embedded in its surface. The cells’ receptors are in place before they ever encounter an antigen 2. The first time an antigen enters the body and is swept into a lymph node, antigenic determinants on its surfa ...
ABSTRACT Douglas Hanahan
... It has been widely hypothesized that, similar to epithelial tissues, tumors are hierarchically organized; only a small number of stem-like cells referred to as cancer stem cells (CSCs) have replicative immortality and is therefore able to maintain and provide tumor growth. However, during tumor prog ...
... It has been widely hypothesized that, similar to epithelial tissues, tumors are hierarchically organized; only a small number of stem-like cells referred to as cancer stem cells (CSCs) have replicative immortality and is therefore able to maintain and provide tumor growth. However, during tumor prog ...
Immune System
... by macrophages and natural killer cells • some of these activated B cells will become memory cells that remain in your body for a long time – ...
... by macrophages and natural killer cells • some of these activated B cells will become memory cells that remain in your body for a long time – ...
the immune system phagocytosis antibody function
... taking premade antibodies that provide temporary protection for people who have been exposed to a specific illness. ...
... taking premade antibodies that provide temporary protection for people who have been exposed to a specific illness. ...
Module 2: Host Defences
... Innate and Adaptive Immune Systems Innate Rapid, first line of defence against infection Adaptive ...
... Innate and Adaptive Immune Systems Innate Rapid, first line of defence against infection Adaptive ...
Reading Guide-InnateImmune (CH15)
... receptors) and indirectly (via opsonization….a process that happens when complement proteins are activated). Some really virulent pathogens have evolved mechanism to evade the process of phagocytosis…can you think of some ways in which an organism could evade phaogcytosis? Cells of the immune syste ...
... receptors) and indirectly (via opsonization….a process that happens when complement proteins are activated). Some really virulent pathogens have evolved mechanism to evade the process of phagocytosis…can you think of some ways in which an organism could evade phaogcytosis? Cells of the immune syste ...
IMMUNOLOGY FINAL EXAM 1. A Major difference between using
... B. Suppression of self-reactive cells by T-cells C. Production of anti-idiotypic antibodies D. Release of inhibitory cytokines by lymphocites 3. Which of the following is a primary lymphoid organ? A. Spleen B. Bone Marrow C. Lymph Node D. Lung E. Gall Bladder 4. A batter for the Astros gets accident ...
... B. Suppression of self-reactive cells by T-cells C. Production of anti-idiotypic antibodies D. Release of inhibitory cytokines by lymphocites 3. Which of the following is a primary lymphoid organ? A. Spleen B. Bone Marrow C. Lymph Node D. Lung E. Gall Bladder 4. A batter for the Astros gets accident ...
document
... Mycophenolic acid potent noncompetitive, inhibitor of inosine monophosphate dehydrogenase (rate-limiting enzyme of de novo pathway) which is involved in the guanine nucleotide biosynthesis pathway. Leukocytes depend on this pathway for production of purines and thus more selective immunosuppression ...
... Mycophenolic acid potent noncompetitive, inhibitor of inosine monophosphate dehydrogenase (rate-limiting enzyme of de novo pathway) which is involved in the guanine nucleotide biosynthesis pathway. Leukocytes depend on this pathway for production of purines and thus more selective immunosuppression ...
Vaccinations teacher answer sheet 2 - e-Bug
... Plasma cells are derived from B cells. Once a B cell recognises a free antigen it can become a plasma cell. These plasma cells are antibody producing cells and so are large in size. 8. Explain why vaccines are preventative in protecting against infection. Vaccines show the antigen for a particular i ...
... Plasma cells are derived from B cells. Once a B cell recognises a free antigen it can become a plasma cell. These plasma cells are antibody producing cells and so are large in size. 8. Explain why vaccines are preventative in protecting against infection. Vaccines show the antigen for a particular i ...
Innate immunity/ cont…II.Second line: 2.Phagocytosis:
... The macrophages produce cytokines as IL-1 & TNF.These activate endothelial cells of nearby venules to produce adhesion molecules (selectin, integrins, & ICAM) and chemkines (e.g.,IL-8) which mediate MIGRATION of leucocytes & monocytes from the blood to tissues (diapedesis). The phagocytes have ...
... The macrophages produce cytokines as IL-1 & TNF.These activate endothelial cells of nearby venules to produce adhesion molecules (selectin, integrins, & ICAM) and chemkines (e.g.,IL-8) which mediate MIGRATION of leucocytes & monocytes from the blood to tissues (diapedesis). The phagocytes have ...
Lymphopoiesis
Lymphopoiesis (lĭm'fō-poi-ē'sĭs) (or lymphocytopoiesis) is the generation of lymphocytes, one of the five types of white blood cell (WBC). It is more formally known as lymphoid hematopoiesis.Pathosis in lymphopoiesis leads to any of various lymphoproliferative disorders, such as the lymphomas and lymphoid leukemias.