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Immune Response to Infection 22.06.2016 onse to Infection
Immune Response to Infection 22.06.2016 onse to Infection

Sept2_Lecture3
Sept2_Lecture3

... 1. Lymph glands: T-cells and B-cells migrate and occupy lymph glands. Macrophages and dendritic cells are present to trap antigens entering the glands (inducer cells) 2. Spleen: another filter of the blood and lymph 3. GALTs: gut associated lymphoid tissues are aggregates of cells found in various o ...
Chapter 7 Cytokines
Chapter 7 Cytokines

... 2. Cytokines come from many kinds of cells----activated immune cells, matrix cells and some tumor cells.  one cell may secrete many kinds of cytokines,  different cells may secrete the same cytokines. ...
7.1 What Are Cells? A cell is the basic unit of structure and function
7.1 What Are Cells? A cell is the basic unit of structure and function

... (1635-1703) was the first to record his observations of cells. In 1663, he took a thin slice of cork and placed it under a microscope that he built. Cork is made from the bark of the cork oak tree, but its cells are no longer alive. Hooke made detailed sketches of his observations. An artist's versi ...
linking the innate and adaptive immune systems
linking the innate and adaptive immune systems

... effector or helper cells, with the latter being able to migrate back into the lymph node. Exposure of NK cells to IL-4 or IL-12 generates NK cells that, when cultured together with DCs, can modulate the polarization of naive T cells. Thus, such NK cells can participate in the T helper type 1 (TH1)–T ...
Defense Against Disease What causes disease? Mechanisms of
Defense Against Disease What causes disease? Mechanisms of

... – He inoculated an 8 year old boy with bacteria possessing the cowpox virus. – Months later, he inoculated the boy with the smallpox virus and he survived the infection. – Soon people all over Europe were being vaccinated against smallpox using the cowpox virus. ...
PowerPoint Presentation - I. Introduction to class
PowerPoint Presentation - I. Introduction to class

... ACTIVITY OF OTHER CELLS OF THE IMMUNE SYSTEM. • DEFENSE AGAINST: • BACTERIA AND VIRUSES THAT ARE INSIDE HOST CELLS AND ARE INACCESSIBLE TO ANTIBODIES. • FUNGI, PROTOZOA, AND WORMS ...
5. Cytokine
5. Cytokine

... The actions of cytokines are often Pleiotropic (多效性)and Redundant(重叠性) Pleiotropic means the ability of one cytokine to act on different cell types. Redundant refers to the property of multiple cytokines having the same functional effects. ...
Antigen processing and presentation
Antigen processing and presentation

Cell-Mediated Immunity Thought Questions Basic Science Review
Cell-Mediated Immunity Thought Questions Basic Science Review

... migrate to the thymus where they undergo further development. On the next page is a diagram of T-cell development and the key receptors present in each stage. (See Figure 54-1.) Antigen recognition in T-cells is mediated by the T-cell receptor (TCR). TCR is similar to the B-cell receptor in that it ...
Document
Document

... The SMART Study (2006) demonstrated the importance of immune activation/inflammation to non HIV co-morbidities and a focus on therapeutic agents to block inflammatory pathways ...
A Concise History of Immunology
A Concise History of Immunology

... immunity to infection could be transferred by a soluble substance in the serum (Von Behring and Kitasato) elaborated by specialized cells of the immune system (Ehrlich) and that the regulation of this process (generation of antibodies) was important to minimize the possibility of developing an immu ...
The Lymphatic System - North Seattle College
The Lymphatic System - North Seattle College

... 2. Some antigen is taken into the B cell, broken down into peptide fragments and combined with the MHC-II self antigen, and moved to the B cell surface ...
Inflammation and immunity
Inflammation and immunity

... Once leucocytes have arrived at a site of infection or inflammation, they release mediators which control the later accumulation and activation of other cells. Inflammatory mediators are soluble, diffusible molecules that act locally at the site of tissue damage and infection and, when present at hi ...
human immune system can respond naturally to fight cancer
human immune system can respond naturally to fight cancer

... reducing cancer rates without having to rely on the single-target-based treatments typically found in current therapies. Having identified a specific type of protective B cell (NIMPAB), her research has now established how vital these can be within the immunological process, due to their ability to ...
Immune System Notes.notebook
Immune System Notes.notebook

... -responses at the cellular level are called specific defenses; different for each pathogen -responses that happen in the same way to every pathogen are called nonspecific responses; fever and inflammation (14) ...
Immune
Immune

... • Your Grandmother may have been an immunologist – Iron is essential for white blood cells – not just RBCs – Sunlight (vitamin/hormone D) is important - Immune cells have 1,25(OH)2D receptors; shifts response towards innate immunity rather than adaptive immunity (inhibits Th1 and Th17, enhances Th2 ...
Scientific Glossary
Scientific Glossary

... Migration inhibition factor (MIF): A lymphokine that inhibits the motility of macrophages in culture. Minor histocompatibility antigens: These antigens, encoded outside the MHC, are numerous, but do not generate rapid graft rejection or primary responses of T cells in vitro. They do not serve as res ...
Chapter 20 The Lymphatic System, Nonspecific Resistance to
Chapter 20 The Lymphatic System, Nonspecific Resistance to

... –Phagocytize foreign substances and cells –Transport them to lymphatic tissues –Process foreign things into individual antigens –Present Ags to T & B lymphocyte to help activate them ...
Elements of Innate and Acquired Immunity
Elements of Innate and Acquired Immunity

... autoimmunity by inducing the release of sequestered antigens or molecular mimicry or by polyclonal activation. - Autoimmune myocraditis has been observed to arise in some cases following a cardiac ischemic attack. It is believed that autoreactivity to cardiac antigens develops as a consequence of ex ...
Antibodies, structure. Classes of Immunoglobulines
Antibodies, structure. Classes of Immunoglobulines

... Bacterium ...
Immunol-molec-med-3-2ndmed
Immunol-molec-med-3-2ndmed

... Cells of the immune system ‘talk’ to each other by producing cytokines like ‘text messages’ informing cells what their function should be! ...
Chapter 13
Chapter 13

... – Proteins produced by cells infected with a virus that protects noninfected cells ...
Notes - Haiku Learning
Notes - Haiku Learning

... 5. Steps of a typical primary immune response a) Specific antigen is identified (cold virus) b) Specific plasma cell is identified that can produce an antibody that will bind to the antigen (proteins of the capsid coat of the cold virus) c) Specific plasma cell type clones itself (division by mito ...
Bone-marrow transplant therapy for RDEB
Bone-marrow transplant therapy for RDEB

... the skin and mature into skin stem cells, thereby helping to repair the skin. Bone-marrow transplant therapy is therefore a type of ‘stem-cell’ therapy, in that it provides the treated patient with a new supply of genetically correct stem cells from the bone marrow of a healthy donor. The faulty cel ...
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Lymphopoiesis



Lymphopoiesis (lĭm'fō-poi-ē'sĭs) (or lymphocytopoiesis) is the generation of lymphocytes, one of the five types of white blood cell (WBC). It is more formally known as lymphoid hematopoiesis.Pathosis in lymphopoiesis leads to any of various lymphoproliferative disorders, such as the lymphomas and lymphoid leukemias.
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