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PLASMA PROTEINS AND IMMUNOGLOBULINES – An Overview
PLASMA PROTEINS AND IMMUNOGLOBULINES – An Overview

... • IgA: contains J chain and secretary component, part of defense against viral and bacterial infections; • IgM: usually first to be made in immune response, contains J chain, in presence of complement are very effective in producing Lysis of cells; ...
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Printer-Friendly Version - ian@doctor

... individual has 6 (3 on each chromosome). These are known as HLA-A, -B and –C. They are all co-expressed, so that each individual has 6 different MHC molecules on each cell. Similarly the MHC-II has multiple genes; they are DP, DQ and DR. Each chromosome 6 has a DPand a DPSimilarly, each has a D ...
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Monoclonal antibody



Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are made by identical immune cells that are all clones of a unique parent cell, in contrast to polyclonal antibodies which are made from several different immune cells. Monoclonal antibodies have monovalent affinity, in that they bind to the same epitope.Given almost any substance, it is possible to produce monoclonal antibodies that specifically bind to that substance; they can then serve to detect or purify that substance. This has become an important tool in biochemistry, molecular biology and medicine. When used as medications, the non-proprietary drug name ends in -mab (see ""Nomenclature of monoclonal antibodies""), and many immunotherapy specialists use the word mab anacronymically.
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