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Translation - Santa Susana High School
Translation - Santa Susana High School

... aligning the active sites and holding them in place. • Structure – ribosomes are made of mostly ribosomal RNA (rRNA) that is made from DNA that resides in the nucleolus – consists of a large unit and a small unit • each is made of rRNA and proteins imported from the cytoplasm • once assembled the 2 ...
Nucleic Acid Isolation System
Nucleic Acid Isolation System

... Cartridge ...
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没有幻灯片标题

... hydrophobic patch on the surface which complements with another hydrophobic patch formed only in deoxygenated HbS, thus generating the fiber precipitates (a polymer of HbS). 1.6.7 Sickle cell trait (heterozygote) confers a small but highly significant degree of protection against the most lethal for ...
Bionano
Bionano

... applies a force to the hairpin causing it to unzip. We are investigating the mechanical properties of nucleic acids by focusing in particular on hairpins. These structures consist of single strands of DNA or RNA whose ends are self-complementary, such that they loop back on themselves to form a dupl ...
bacterial growth and measurement-2012
bacterial growth and measurement-2012

... Bacterial growth curve represents a batch culture and or closed system. Because no fresh medium is provided during incubation, nutrient concentration decline and concentration of waste increases. The bacterial growth curve has the four distinct phases. a) Lag Phase, b) Exponential Phase, c) Stationa ...
25Ch03nucleicacids2008
25Ch03nucleicacids2008

Section 3 - Carbon Compounds
Section 3 - Carbon Compounds

... include galactose, which is a component of milk, and fructose, which is found in many fruits. The large macromolecules formed from monosaccharides are known as polysaccharides. Many animals store excess sugar in a polysaccharide called glycogen, or animal starch. When the level of glucose in your bl ...
A Review of the Methods available for the Determination of the
A Review of the Methods available for the Determination of the

... argues, therefore, for the presence of salt-links. If the protein is more soluble in acids than in alkalis, then there is a preponderance of basic side chains, and if more soluble in alkalis than acids, a preponderance of acid side chains. Any factor increasing the dielectric constant of the medium ...
File - USF Scholarship Repository
File - USF Scholarship Repository

... In a previous study, we investigated whether any cellular chemokine might be a ligand for US27. While no chemokine ligands were identified, the results indicated that US27 might enhance the signaling of human chemokine receptor CXCR4. In this study, the effect of US27 on CXCR4 function was further e ...
Section 2: Enzymes and Digestion
Section 2: Enzymes and Digestion

... There are 4 main parts that make up the general structure of an amino acid. There is: The amino group (NH2) this is a basic part of the molecule where it gets the name amino. The carboxyl group (COOH) this is an acid group. The hydrogen atom (H) The r group, this can be a variety of chemicals. Each ...
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Human MSP R/Ron PerCP

... for IL­3, EPO­R, EGFR, IGF­IR, Plexins B1 and B3, and CD44v6. RON may also be found intracellularly, where it interacts with either the androgen receptor or EGFR  in the cytoplasm, or in the nucleus, where it acts as a transcription factor coupled to HIF­1a and regulates c­Jun, Bcl­2 and c­FLIP expr ...
Extracting Milk Proteins
Extracting Milk Proteins

... Proteins have several levels of structure. The amino acid sequence forms the primary protein structure. When the amino acid sequences become linked, they form either sheets or helixes called the secondary structure. These secondary structures interact to form globular 3D shapes called the tertiary s ...
AHP Versus Iodine and Iodophors
AHP Versus Iodine and Iodophors

... It is believed that oxidizing actives will not allow for resistance development when targeting organisms. Although solutions of iodine in alcohol and iodine in potassium iodide (e.g., Lugols solution) have been used for many years, these formulations have now largely been replaced by solubilized pre ...
Nucleic acids
Nucleic acids

... (i) DNA- Genomic information (nucleosomes, chromatin) •This chemical substance is present in the nucleus of all cells in all living organisms •It controls all the chemical changes which take place in cells • The kind of cell which is formed, (muscle, blood, nerve etc) is controlled by DNA • The kin ...
Central Dogma Mini-Book Instructions
Central Dogma Mini-Book Instructions

... Story 1: Story of a Castle Once upon a time, there were directions to build a beautiful castle. The only problem was, these directions were locked in a library and couldn’t get out. One day, a person started to make copies of the directions. The copies left the library to be in the world outside of ...
Polymer Principles
Polymer Principles

... to how a key (substrate) fits into a lock (enzyme). Enzyme specificity is related to the complementary shapes of the enzyme and substrate molecules. Each substrate, or key, fits into a specific enzyme, or lock. ...
Bio Keystone Review
Bio Keystone Review

... Any individual living thing. All living things have common characteristics: are made of cells; reproduce; are based on a universal genetic code; grow and develop; obtain materials and use energy; respond to the environment (stimulus/response); maintain a stable internal environment (through homeosta ...
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6 Protein_Synthesis - bloodhounds Incorporated

learning outcomes for biology 12 and ib biology 12
learning outcomes for biology 12 and ib biology 12

... mRNA, tRNA, and ribosomes in the processes of transcription and translation F2. Determine the sequence of amino acids coded for by a specific DNA sequence, given a table of mRNA codons p. 469 F3. Give examples of two environmental mutagens that can cause mutations in humans p.478. 446 F4. Use exampl ...
FREE Sample Here
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... 14. Which of the following is a true statement about non-covalent bonds? a. They are all the result of electron sharing. b. Hydrogen bonds, ionic bond and hydrophobic interactions all carry a degree of specificity while van der Waals interactions are induced. c. All noncovalent bonds are formed betw ...
AP Biology
AP Biology

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No Slide Title

... Forces involved in structure ...
Pharos university Faculty of Allied Medical SCIENCE Biochemistry 1
Pharos university Faculty of Allied Medical SCIENCE Biochemistry 1

... By the end of this lecture, students will learn: ...
The Exocytic/Lysosomal Transport Pathway
The Exocytic/Lysosomal Transport Pathway

Bis2A 10.1 Structure of Bacteria and Archaea
Bis2A 10.1 Structure of Bacteria and Archaea

... Transduction results in a recombinant organism. Archaea are not aected by bacteriophages but instead have their own viruses that translocate genetic material from one individual to another. In conjugation, DNA is transferred from one prokaryote to another by means of a pilus, which brings the organ ...
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Cell-penetrating peptide



Cell-penetrating peptides (CPPs) are short peptides that facilitate cellular uptake of various molecular cargo (from nanosize particles to small chemical molecules and large fragments of DNA). The ""cargo"" is associated with the peptides either through chemical linkage via covalent bonds or through non-covalent interactions. The function of the CPPs are to deliver the cargo into cells, a process that commonly occurs through endocytosis with the cargo delivered to the endosomes of living mammalian cells.CPPs hold great potential as in vitro and in vivo delivery vectors for use in research and medicine. Current use is limited by a lack of cell specificity in CPP-mediated cargo delivery and insufficient understanding of the modes of their uptake.CPPs typically have an amino acid composition that either contains a high relative abundance of positively charged amino acids such as lysine or arginine or has sequences that contain an alternating pattern of polar/charged amino acids and non-polar, hydrophobic amino acids. These two types of structures are referred to as polycationic or amphipathic, respectively. A third class of CPPs are the hydrophobic peptides, containing only apolar residues, with low net chargeor have hydrophobic amino acid groups that are crucial for cellular uptake.The first CPP was discovered independently by two laboratories in 1988, when it was found that the trans-activating transcriptional activator (TAT) from human immunodeficiency virus 1 (HIV-1) could be efficiently taken up from the surrounding media by numerous cell types in culture. Since then, the number of known CPPs has expanded considerably and small molecule synthetic analogues with more effective protein transduction properties have been generated.
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