7Nt Release
... Neuroendocrine cells derived from adrenal medulla with large dense-core vesicles. Can measure membrane fusion (capacitance measurements), or direct release of catecholamine transmitters using carbon fiber electrodes (amperometry) ...
... Neuroendocrine cells derived from adrenal medulla with large dense-core vesicles. Can measure membrane fusion (capacitance measurements), or direct release of catecholamine transmitters using carbon fiber electrodes (amperometry) ...
Leaving Cert Biology Notes - Learning Outcomes 2014
... Messenger RNA (mRNA) carries information to ribosome o The opening of the helix by enzyme action o Synthesis of complementary nucleic acid chains alongside the existing chains o Formation of two identical helices Define as Analyses DNA of an individual for accurate identification by comparison 2 app ...
... Messenger RNA (mRNA) carries information to ribosome o The opening of the helix by enzyme action o Synthesis of complementary nucleic acid chains alongside the existing chains o Formation of two identical helices Define as Analyses DNA of an individual for accurate identification by comparison 2 app ...
Bacterial Classification
... American chemists Woodward and W.E. Doering Since then, several more efficient quinine syntheses have been achieved, but none of them can compete in economic terms with isolation of the alkaloid from natural sources. Malaria resistant to synthetic but less so to natural The first synthetic organic d ...
... American chemists Woodward and W.E. Doering Since then, several more efficient quinine syntheses have been achieved, but none of them can compete in economic terms with isolation of the alkaloid from natural sources. Malaria resistant to synthetic but less so to natural The first synthetic organic d ...
4th seminar (ELISA, functional)_2016
... normally produced during fetal development. serum from individuals with colorectal and other carcinomas had higher levels of CEA than healthy individuals and can be used to monitor the response to colon cancer treatment. ...
... normally produced during fetal development. serum from individuals with colorectal and other carcinomas had higher levels of CEA than healthy individuals and can be used to monitor the response to colon cancer treatment. ...
Filtration Processes Applied in Vaccine Production
... vaccines can be tailor made to treat specific individuals. Veterinary vaccines also have important economic significance in the protection of animal stocks. All vaccines have at least two common elements: they must be immunogenic and they must be produced in a highly purified formable to be safely a ...
... vaccines can be tailor made to treat specific individuals. Veterinary vaccines also have important economic significance in the protection of animal stocks. All vaccines have at least two common elements: they must be immunogenic and they must be produced in a highly purified formable to be safely a ...
Document
... • In a cell based assay • ~25 x 103 cells/well (2 billion times less cells) • EC50s can be in the range of pg/mL (10-10 - 10-12 g/mL)! • for an antibody (150kDa), 1pg/mL is ~600 molecules/uL • in 100uL, this is ~ 60000 molecules! • just a few molecules are enough to perform the function Kamikura MBS ...
... • In a cell based assay • ~25 x 103 cells/well (2 billion times less cells) • EC50s can be in the range of pg/mL (10-10 - 10-12 g/mL)! • for an antibody (150kDa), 1pg/mL is ~600 molecules/uL • in 100uL, this is ~ 60000 molecules! • just a few molecules are enough to perform the function Kamikura MBS ...
Performance Level Descriptors
... Describe the regulatory effect of positive or negative feedback processes in a complex biological system. Evaluate the validity and reliability of a given scientific investigation of a biological system. Explain how a relationship between variables in a scientific investigation of a biological sy ...
... Describe the regulatory effect of positive or negative feedback processes in a complex biological system. Evaluate the validity and reliability of a given scientific investigation of a biological system. Explain how a relationship between variables in a scientific investigation of a biological sy ...
Molecular dynamics simulation studies of lipid bilayer
... control of interactions between the cell and its environment, separation of intracellular compartments, and receiving and transducing signals necessary for the cell functioning. As was elegantly shown by Gorter & Grendel (1925), the common structural feature of biological membranes is a lipid bilaye ...
... control of interactions between the cell and its environment, separation of intracellular compartments, and receiving and transducing signals necessary for the cell functioning. As was elegantly shown by Gorter & Grendel (1925), the common structural feature of biological membranes is a lipid bilaye ...
Natural Products and Nutritional Supplements as
... in the Dietary Supplement Health and Education Act (DSHEA) “A dietary supplement is a product taken by mouth that contains a "dietary ingredient" intended to supplement the diet. The "dietary ingredients" in these products may include: vitamins, minerals, herbs or other botanicals, amino acids, and ...
... in the Dietary Supplement Health and Education Act (DSHEA) “A dietary supplement is a product taken by mouth that contains a "dietary ingredient" intended to supplement the diet. The "dietary ingredients" in these products may include: vitamins, minerals, herbs or other botanicals, amino acids, and ...
General Biochemistry Chemistry of Polysaccharides
... Glycogen and starch ingested in the diet are hydrolyzed by α amylases, enzymes in saliva and intestinal secretions that break (α 1-4 ) glycosidic bonds between glucose units. ...
... Glycogen and starch ingested in the diet are hydrolyzed by α amylases, enzymes in saliva and intestinal secretions that break (α 1-4 ) glycosidic bonds between glucose units. ...
TEXT The cell cycle, or cell-division cycle, is the series of events that
... they are still in the form of loosely packed chromatin fibers. The G2 phase prepares the cell for mitosis (M phase) which is initiated by prophase. At the end of this gap phase is a control checkpoint (G2 checkpoint), a different Cdk-cyclin kinase complex (protein kinase) termed the M-phase promotin ...
... they are still in the form of loosely packed chromatin fibers. The G2 phase prepares the cell for mitosis (M phase) which is initiated by prophase. At the end of this gap phase is a control checkpoint (G2 checkpoint), a different Cdk-cyclin kinase complex (protein kinase) termed the M-phase promotin ...
The key to life at the atomic level
... The answer was provided at the beginning of the 1960s. Scientists realized that the genetic message is copied to a RNA molecule (figure 3). They called it messenger RNA (mRNA). mRNA moves outside the nucleus and is caught by the ribosome, which uses mRNA as a blueprint for producing proteins. When ...
... The answer was provided at the beginning of the 1960s. Scientists realized that the genetic message is copied to a RNA molecule (figure 3). They called it messenger RNA (mRNA). mRNA moves outside the nucleus and is caught by the ribosome, which uses mRNA as a blueprint for producing proteins. When ...
Judge, P.J. and Watts, A.
... an integral membrane protein (left) in domains, or at the protein interface, in this case, retinal rhodopsin, a GPCR [13]. Figure courtesy of Klaus Gawrich, NIH, Bethesda, USA. (c) Oriented lipid (DOPC:DOPE) bilayers containing 15N labelled membrane peptides give rise to wide line NMR spectra (as a ...
... an integral membrane protein (left) in domains, or at the protein interface, in this case, retinal rhodopsin, a GPCR [13]. Figure courtesy of Klaus Gawrich, NIH, Bethesda, USA. (c) Oriented lipid (DOPC:DOPE) bilayers containing 15N labelled membrane peptides give rise to wide line NMR spectra (as a ...
oh-chotteau-20090423.. - PAW Bioscience Products
... Example of fed-batch (Wurm 2004 cited ‘courtesy of Lonza’) ...
... Example of fed-batch (Wurm 2004 cited ‘courtesy of Lonza’) ...
Student 1 Response
... Protein molecules consist of subunits called amino acids. These form in a single chain held together by peptide bonds forming an initial or primary structure. This structure becomes a secondary structure when the first chain folds specifically into a new shape held by hydrogen bonds, making a helica ...
... Protein molecules consist of subunits called amino acids. These form in a single chain held together by peptide bonds forming an initial or primary structure. This structure becomes a secondary structure when the first chain folds specifically into a new shape held by hydrogen bonds, making a helica ...
RNA Interference
... Double-stranded RNA can be introduced experimentally to silence target genes interested Nature 418:244-251, 2002 37 ...
... Double-stranded RNA can be introduced experimentally to silence target genes interested Nature 418:244-251, 2002 37 ...
Section 8: Genetic Mutations, Ribosome Structure
... robust prokaryotic specificity is exerted). The RNA polymerase and protein synthesis inhibitors highlight examples of antibiotics that target prokaryotic-specific regions of conserved molecules present in both prokaryotes and eukaryotes. We primed students for the upcoming discussion upon introducti ...
... robust prokaryotic specificity is exerted). The RNA polymerase and protein synthesis inhibitors highlight examples of antibiotics that target prokaryotic-specific regions of conserved molecules present in both prokaryotes and eukaryotes. We primed students for the upcoming discussion upon introducti ...
Protective Effect of an Isoflavone, Tectorigenin, Against Oxidative
... required to degrade 1 M H2O2. Protein expression of catalase, phospho-extracellular signal-regulated kinase (ERK), IB-, and NF-B were evaluated by Western blot analysis. A mobility shift assay was performed to assess the DNA-binding ability of NF-B. Transient transfection and a NF-B luciferase ...
... required to degrade 1 M H2O2. Protein expression of catalase, phospho-extracellular signal-regulated kinase (ERK), IB-, and NF-B were evaluated by Western blot analysis. A mobility shift assay was performed to assess the DNA-binding ability of NF-B. Transient transfection and a NF-B luciferase ...
SuccFind: a novel succinylation sites online
... establish a reliable and comprehensive dataset. However, while only a small amount of known succinylation sites was detected, experimental verification of succinylated substrates is labor-intensive, time-consuming and biased toward abundant proteins and proteotypic peptides. Thus, in silicon predict ...
... establish a reliable and comprehensive dataset. However, while only a small amount of known succinylation sites was detected, experimental verification of succinylated substrates is labor-intensive, time-consuming and biased toward abundant proteins and proteotypic peptides. Thus, in silicon predict ...
SCIENCE BOOKLET GRADE 7
... a membrane-bound organelle that contains genetic material the outer covering of a cell that separates it from the environment the structure that contains the information about how to make a cell’s proteins ...
... a membrane-bound organelle that contains genetic material the outer covering of a cell that separates it from the environment the structure that contains the information about how to make a cell’s proteins ...
Intorduction to basic vaccine technology - UK-CAB
... Offers protection for a long time Low cost Stability and ease of administration Works against a wide range of different strains ...
... Offers protection for a long time Low cost Stability and ease of administration Works against a wide range of different strains ...
Biology Cytology (study of the cells) Basic characteristics of the cells
... (double ring purine(A, G) or single ring pyrimidine (C, T. U replace T in RNA). Some types of RNA have catalytic activity similar to that of enzymes. Types of nucleic acids. - In cells: Deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). ...
... (double ring purine(A, G) or single ring pyrimidine (C, T. U replace T in RNA). Some types of RNA have catalytic activity similar to that of enzymes. Types of nucleic acids. - In cells: Deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). ...
Research news
... In early studies of empiric structure–activity relationships, monodentate PtII complexes were considered to be biologically inactive. Examples of such inactive monodentate PtII compounds are [PtCl(dien)]+ (dien=diethylentriamine) and [PtCl(NH3)3]+. DNA is considered the major biological target of pl ...
... In early studies of empiric structure–activity relationships, monodentate PtII complexes were considered to be biologically inactive. Examples of such inactive monodentate PtII compounds are [PtCl(dien)]+ (dien=diethylentriamine) and [PtCl(NH3)3]+. DNA is considered the major biological target of pl ...
Cell-penetrating peptide
Cell-penetrating peptides (CPPs) are short peptides that facilitate cellular uptake of various molecular cargo (from nanosize particles to small chemical molecules and large fragments of DNA). The ""cargo"" is associated with the peptides either through chemical linkage via covalent bonds or through non-covalent interactions. The function of the CPPs are to deliver the cargo into cells, a process that commonly occurs through endocytosis with the cargo delivered to the endosomes of living mammalian cells.CPPs hold great potential as in vitro and in vivo delivery vectors for use in research and medicine. Current use is limited by a lack of cell specificity in CPP-mediated cargo delivery and insufficient understanding of the modes of their uptake.CPPs typically have an amino acid composition that either contains a high relative abundance of positively charged amino acids such as lysine or arginine or has sequences that contain an alternating pattern of polar/charged amino acids and non-polar, hydrophobic amino acids. These two types of structures are referred to as polycationic or amphipathic, respectively. A third class of CPPs are the hydrophobic peptides, containing only apolar residues, with low net chargeor have hydrophobic amino acid groups that are crucial for cellular uptake.The first CPP was discovered independently by two laboratories in 1988, when it was found that the trans-activating transcriptional activator (TAT) from human immunodeficiency virus 1 (HIV-1) could be efficiently taken up from the surrounding media by numerous cell types in culture. Since then, the number of known CPPs has expanded considerably and small molecule synthetic analogues with more effective protein transduction properties have been generated.