• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Cells: The Basic Units of Life
Cells: The Basic Units of Life

... barrier. It separates the cell’s contents from its environment. The cell membrane also controls materials going into and out of the cell. Inside the cell is a fluid. This fluid and almost all of its contents are called the cytoplasm (SIET oh PLAZ uhm). ...
Metabolism of bilirubin and bile salts synthesis (uronic acid pathway
Metabolism of bilirubin and bile salts synthesis (uronic acid pathway

... also called direct bilirubin, being water soluble reacts immediately with diazo reagent unconjugated (albumin bound) bilirubin is called indirect bilirubin. Being water insoluble, it has to be first extracted with methanol and then treated with diazo reagent ...
Archaea 1
Archaea 1

... • thermoacidophiles: love heat and acid  • psychrophiles: those that live at unusually cold temperatures ...
Specification sheet
Specification sheet

... Glycophorin A, also known as CD235a, is the major intrinsic membrane protein of the erythrocyte. The Nterminal glycosylated segment, which lies outside of the erythrocyte membrane, has MN blood group receptors. It is important for the function of SLC4A1 and required for the high activity of SLC4A1. ...
Screening Applications
Screening Applications

... transilluminator (12). In addition, Promega recently introduced a non-isotopic fluorescencebased detection product, the FluoroTect™ Green Lys in vitro Translation Labeling System ...
Quiz Show A
Quiz Show A

... Question: Which of the following explains why normal cells grown in a Petri dish tend to stop growing once they have covered the bottom of the dish? a. The cells lack cyclin. b. The Petri dish inhibits growth. c. Contact with other cells stops cell growth. d. Most cells grown in Petri dishes have de ...
Replicons
Replicons

Powerpoint
Powerpoint

... Example of the strategies to develop a thiol tag that can be applied to proteomics. Landar, A., Oh, J. Y., Giles, N. M., Isom, A., Kirk, M., Barnes, S. and Darley-Usmar, V. M. (2006) A sensitive method for the quantitative measurement of protein thiol modification in response to oxidative stress. Fr ...
PCT/MIA/8/2 ADD.2
PCT/MIA/8/2 ADD.2

... PCT Rule 13 specifies that the international application shall relate to one invention only or to a group of inventions so linked as to form a single general inventive concept (“requirement of unity of invention”). The rule further states that the requirement is fulfilled only when there is a techni ...
Nutricoll Marine Collagen brochure
Nutricoll Marine Collagen brochure

... increase the skin moisture level by 12 % in a period of 8 weeks. A consistent increase in the skin collagen density over 12 weeks was confirmed by increased dermal echogenicity. Ex vivo studies confirmed the results of the clinical trials and showed an increased amount of water-binding glycosaminogl ...
alborz-final
alborz-final

... Abstract: Considerable advances have been made in the area of cell signaling models, but in order for these models to be biologically relevant, precise, time dependant, quantitative and high-throughput proteomic data is required. Several methods to detect proteins such as non-isotopic labeling based ...
March 28
March 28

... At  Division  of  Informa@on  Coding  we  run  a  project  aimed  at  understanding   (modelling)  how  a  complex  organism  is  developed  from  a  single  egg  cell.  We   believe  that  this  is  fundamentally  a  ques@on  about   ...
Thermo Scientific Solutions for Quantitative
Thermo Scientific Solutions for Quantitative

... IN CELL CULTURE (SILAC) is a powerful and widely used method of identifying and quantifying relative changes in complex protein samples. It can be applied to complex biomarker discovery and systems biology studies as well as to isolated proteins and protein complexes. As its name implies, SILAC invo ...
Urine formation by kidney.
Urine formation by kidney.

... • Urea, creatinine, uric acid and urates=poorly reabsorbed • Foreign substances and drugs= poorly reabsorbed, secreted from the blood into the tubules, so that their excretion rates are high. • Sodium ions, chloride ions, and bicarbonate ions, are highly reabsorbed, so that only small amounts appear ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)

... twenty amino acids. The main chains of all these amino acids are identical. The difference in the side chain in these 20 amino acids incorporates diversity in structure-function relationship in proteins adapted in different environments. Substitution, deletion and insertion are the available mechani ...
Extraction of Nuclear Region from Sputum Images through Pixel
Extraction of Nuclear Region from Sputum Images through Pixel

... Lung Cancer constitutes the major portion of all deaths that occur due to cancer. This deadly disease Cancer is staged according to its severity and also up to where it has spread. It has been said by many doctors and researchers that a survival rate of five years can be increased if lung cancer is ...
Acid Carboxypeptidases: Their Occurrence in Plants, Intracellular
Acid Carboxypeptidases: Their Occurrence in Plants, Intracellular

... which has not passed through further development) and of the Angiosperms. Carboxypeptidase activity, finally, is present in the thermophilic fungi Talaromyces duponti (Ascomycetes) Humicula lanuginosa (Deuteromycetes); these enzymes, however, belong to a different family of alkaline carboxypeptidase ...
slides - NMRbox
slides - NMRbox

... reorientation. NMR assignment is complicated, and generally requires 13C / 15N labeled protein. Y Aubin, DJ Hodgson, WB Thach, G Gingras, and S Sauvé: Monitoring Effects of Excipients, Formulation Parameters and Mutations on the High Order Structure of Filgrastim by NMR. Pharm Res., 32, 3365-3375 (2 ...
Testing Methylation Pathways
Testing Methylation Pathways

... for making, maintaining and repairing DNA. ...
Heat Shock Proteins
Heat Shock Proteins

... HSP90α (N-terminal) Inhibitor Screening Assay Kit HSP90α (C-terminal) Inhibitor Screening Assay Kit HSP90β (N-terminal) Inhibitor Screening Assay Kit ...
LABORATORY 3: Site-Directed Mutagenesis of Blue
LABORATORY 3: Site-Directed Mutagenesis of Blue

... screening or selection from massive numbers of mutants to obtain the desired mutation. However, with the advent of recombinant DNA techniques, it became possible to make specific changes to the genome. This method, known as site directed mutagenesis, earned its inventor Michael Smith the 1993 Nobel ...
Document
Document

... UNIT-I: Molecular Tools in Genetic Engineering Restriction Endonucleases, Modification methylases and other enzymes needed in genetic Engineering. Cloning vectors: Plasmids and plasmid vectors, Phages and Phage derived Vectors, Phagemids, Cosmids, artificial chromosome vectors (YAC, BAG). Animal vir ...
IBC Reviewer Form - Benaroya Research Institute
IBC Reviewer Form - Benaroya Research Institute

... recombinant or synthetic nucleic acid molecules, or nucleic acids derived therefrom, into the germ-line (transgenic animals) and experiments involving viable recombinant or synthetic nucleic acid molecule-modified microorganisms tested on whole animals. For the latter, other than viruses which are o ...
ALAMO HEIGHTS INDEPENDENT SCHOOL DISTRICT ALAMO
ALAMO HEIGHTS INDEPENDENT SCHOOL DISTRICT ALAMO

... (D) recognize that longterm survival of species is dependent on changing resource bases that are limited (E) describe the flow of matter through the carbon and nitrogen cycles and explain the consequences of disrupting these cycles (F) describe how environmental change can impact ecosystem stabilit ...
Transcription and Translation
Transcription and Translation

... - Promoters in eukaryotic DNA are more diverse than bacterial promoters. o Eukaryotic promoters include the TATA box and other important diverse sequences. - Eukaryotic RNA polymerases recognize promoters using basal transcription factors instead of a sigma protein. - Termination of eukaryotic prote ...
< 1 ... 25 26 27 28 29 30 31 32 33 ... 262 >

Cell-penetrating peptide



Cell-penetrating peptides (CPPs) are short peptides that facilitate cellular uptake of various molecular cargo (from nanosize particles to small chemical molecules and large fragments of DNA). The ""cargo"" is associated with the peptides either through chemical linkage via covalent bonds or through non-covalent interactions. The function of the CPPs are to deliver the cargo into cells, a process that commonly occurs through endocytosis with the cargo delivered to the endosomes of living mammalian cells.CPPs hold great potential as in vitro and in vivo delivery vectors for use in research and medicine. Current use is limited by a lack of cell specificity in CPP-mediated cargo delivery and insufficient understanding of the modes of their uptake.CPPs typically have an amino acid composition that either contains a high relative abundance of positively charged amino acids such as lysine or arginine or has sequences that contain an alternating pattern of polar/charged amino acids and non-polar, hydrophobic amino acids. These two types of structures are referred to as polycationic or amphipathic, respectively. A third class of CPPs are the hydrophobic peptides, containing only apolar residues, with low net chargeor have hydrophobic amino acid groups that are crucial for cellular uptake.The first CPP was discovered independently by two laboratories in 1988, when it was found that the trans-activating transcriptional activator (TAT) from human immunodeficiency virus 1 (HIV-1) could be efficiently taken up from the surrounding media by numerous cell types in culture. Since then, the number of known CPPs has expanded considerably and small molecule synthetic analogues with more effective protein transduction properties have been generated.
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report