• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
VJJ Class - 6 Mark Question File
VJJ Class - 6 Mark Question File

... • Enzymes are highly specific for their substrate • The action of enzymes in terms of the ‘lock-and-key’ hypothesis • Describe how enzymes can be denatured due to changes in the shape of the active site ...
Biology 1 Unit 2 2. Chemistry: Atoms, Compounds, Water, pH
Biology 1 Unit 2 2. Chemistry: Atoms, Compounds, Water, pH

... Steroid – a type of lipid that can be present in cell membranes or can make up certain hormones Steroid – a type of lipid that can be present in cell membranes or can make up certain hormones Cholesterol – a type of steroid used in cell membranes and also use to make steroid hormones Wax – a type of ...
Biosynthesis and degradation of proteins
Biosynthesis and degradation of proteins

... Protein degradation systems Ubiquitin and proteasome Activation of proteases Protease inhibitors ...
Control of Cell Adhesion
Control of Cell Adhesion

... ¾ Receptor activation by a chemical messenger is only the initial event. In order to produce cellular responses, many other molecular steps are necessary. The sequences of these events is generally referred to as “signal transduction pathways” ...
Replication, Transcription, and Translation
Replication, Transcription, and Translation

Immunology_II_non-specific_immunity
Immunology_II_non-specific_immunity

... TOLL-like receptors –surface or intracellular receptors recognizing various PAMPS. Expressed on dendritic cells, macrophages, granulocytes, epitelial cells…. They induce activation of these cells. ...
Plant Cell Cycle
Plant Cell Cycle

... • A cell will not divide if: – Signals from surrounding cells tell the cell not to divide – There are not enough nutrients to provide for cell growth – The DNA within the nucleus has not been ...
A1984SY56700001
A1984SY56700001

... acts with epsilon amino sidechains of lysine residues of proteins, showed promise. This had the additional advantage of altering different amino acid residues from tyrosine and histidine substituted in direct oxidative iodination. “There followed a long period of development of the method at the end ...
Cloning - Schoolwires
Cloning - Schoolwires

... copy. Offspring are produced asexually. ...
Biochemistry
Biochemistry

... The sequence of bases on a strand of DNA is not random. The sequence provides information for the sequence of amino acids in the synthesis of proteins. The ‘code’ used is called the triplet code where three bases together identify a single amino acid. A molecule called messenger RNA copies a sectio ...
Organisation
Organisation

... nonresponders using microarray analysis. Expression of selected genes, which correlate with response to treatment, will be validated on gene and protein level. A panel of potential predictive marker genes, will be also analysed by QRT-PCR technique in population of cancer cells isolated by laser-cap ...
Unit 1 – Cell Biology
Unit 1 – Cell Biology

... to a ribosome, where the protein is assembled from amino acids. 5 Proteins and enzymes a. The variety of protein shapes and functions arises from the sequence of amino acids. b. Functions of proteins to include structural, enzymes, hormones, antibodies and receptors. c. Enzymes function as biologica ...
Instructor`s Answer Key
Instructor`s Answer Key

... the active site of enzymes and the oxygen-carrying ability of hemoglobin), any alteration in the tertiary structure can seriously disrupt the three-dimensional shape and hence, its physiological activity. 2. If the aqueous (polar) organ solvent extract does not work but the benzene (nonpolar) solven ...
1 Commentars of cell biology to Junqueira`s Basic Histology for the
1 Commentars of cell biology to Junqueira`s Basic Histology for the

... Note (Figs. 2-2, 2-3): every transmembrane protein is integral protein but not vice versa! Note (p. 20 top) receptors have different functions a) signal perception (not only protein hormones, but any signal molecules, light, etc.) b) cell or extracellular matrix adhesion; c) cell recognition (tissue ...
Topic One: Chemistry of Living Things
Topic One: Chemistry of Living Things

...  Dissolves other molecules into solution, allowing them to be transported through the body. B) Oxygen (______): Needed by most (not all) organisms for cellular respiration.  Released by plants and algae as a waste product of _________________________.  Aerobic respiration: Process that uses oxyge ...
Antimicrobial Drugs
Antimicrobial Drugs

Why Do Cells Need to Reproduce?
Why Do Cells Need to Reproduce?

... Cell division occurs during the stage of Mitosis. During this stage, new cells with identical genetic information are formed. The genetic material and cytoplasm are equally divided between two cells. What is the genetic material? ...
12 Complement system BA
12 Complement system BA

... produced in the liver in an inactive form (zymogen). Activation is induced by proteolitic cleavage. ...
Design of a novel globularprotein with atommic
Design of a novel globularprotein with atommic

... • When shifts from T to R the iron moves to the center of the heme plane because an overall structural shift. This shift then gets propagated throughout the structure and leads to the change in other subunits COOPERATIVE BINDING: with the binding of the first The others will bind much easier ...
Unit 2, Module 2 Biochemistry - rev 2012
Unit 2, Module 2 Biochemistry - rev 2012

EOC Final Review
EOC Final Review

... How do cells know what type of cell Some GENES are turned to become? ON (expressed) and other I am a cell with genes turned on to make proteins for CARRYING OXYGEN genes are turned OFF. AROUND THE BODY? RED BLOOD cells This is called GENE EXPRESSION ...
Cell activity
Cell activity

... oxygen, carbon dioxide, water, salts, sugars and amino acids to pass through it, but will not allow large molecules such as proteins to cross it. So it regulates what leaves or enters the cell. The nucleus contains the chromosomes and genes which are involved in inheritance, cell division, growth an ...
Supplementary Figure Legends (doc 40K)
Supplementary Figure Legends (doc 40K)

... Supplementary Figure S3. MDR cells transfected with Stat3 siRNA were resistant to vincristine and adriamycin and constitutively-activated Stat3 did not significantly affect the sensitivity of parental KB cells to tanshinone-1. (a, b) MCF7/ADR and KB/VCR cells were transfected with siStat3 for 24 h a ...
Leq: what is cloning and how is it done?
Leq: what is cloning and how is it done?

... born “old” because her DNA was from an adult sheep. Her telomeres were shorter than other sheep of her age but not as short as an “old” sheep. This could have played a role in her short life span (6 years – normal 11 to 14 years) Before she died of cancer she was able to give birth to 6 lambs, the f ...
1999 AP Biology Exam - Speedway High School
1999 AP Biology Exam - Speedway High School

... (C) Stability is achieved when selection favors the heterozygote, while both types of homozygotes are at a relative disadvantage. (D) Evolutionary changes consist of rapid bursts of speciation alternating with long periods in which species remain essentially unmodified. (E) Under competition for ide ...
< 1 ... 151 152 153 154 155 156 157 158 159 ... 262 >

Cell-penetrating peptide



Cell-penetrating peptides (CPPs) are short peptides that facilitate cellular uptake of various molecular cargo (from nanosize particles to small chemical molecules and large fragments of DNA). The ""cargo"" is associated with the peptides either through chemical linkage via covalent bonds or through non-covalent interactions. The function of the CPPs are to deliver the cargo into cells, a process that commonly occurs through endocytosis with the cargo delivered to the endosomes of living mammalian cells.CPPs hold great potential as in vitro and in vivo delivery vectors for use in research and medicine. Current use is limited by a lack of cell specificity in CPP-mediated cargo delivery and insufficient understanding of the modes of their uptake.CPPs typically have an amino acid composition that either contains a high relative abundance of positively charged amino acids such as lysine or arginine or has sequences that contain an alternating pattern of polar/charged amino acids and non-polar, hydrophobic amino acids. These two types of structures are referred to as polycationic or amphipathic, respectively. A third class of CPPs are the hydrophobic peptides, containing only apolar residues, with low net chargeor have hydrophobic amino acid groups that are crucial for cellular uptake.The first CPP was discovered independently by two laboratories in 1988, when it was found that the trans-activating transcriptional activator (TAT) from human immunodeficiency virus 1 (HIV-1) could be efficiently taken up from the surrounding media by numerous cell types in culture. Since then, the number of known CPPs has expanded considerably and small molecule synthetic analogues with more effective protein transduction properties have been generated.
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report