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The Molecular Basis of Inheritance
The Molecular Basis of Inheritance

... A human cell can copy its 6 billion base pairs and divide into daughter cells in only a few hours. ...
AWC Summer Studentship Report_Will Stovall
AWC Summer Studentship Report_Will Stovall

... The New Zealand fur seal (Arctocephalus forsteri), a member of the mammalian order Pinnipedia, is a relatively common feature of rocky coasts around the South Island of New Zealand. The species is showing strong recovery following exploitation to near extinction in the 19th century, but still faces ...
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N - University of California, Berkeley

... Glutathion (GSH) plays an essential role in deactivation (protective mechanism of AFB1); mice have higher GST levels than rats and rats are more susceptible to cancer from AFB . ...
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Biotechnology - Sterlingmontessoriscience

... determining public health. For example, for years we have thought that "juvenile", or Type 1, diabetes appeared in a human at a relatively young age depending on genes inherited by that human from his/her ancestors. ...
Population vocab
Population vocab

... the principle that allele frequencies in a population will remain constant unless one or more factors cause the frequencies to change and developed an equation to predict the frequency of alleles in a population ...
Chromosome Allele - GZ @ Science Class Online
Chromosome Allele - GZ @ Science Class Online

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Transcription and Translation

... Each triplet code on a DNA molecule is transcribed into a triplet codon on the mRNA molecule. • If the DNA codes for a polypeptide is T-A-C—C-C-G—T-A-G—C-T-T—A-C-T • What would the codons on the complimentary strand of mRNA codons look like? A-U-G – G-G-C – A-U-C – G-A-A – U-G-A • DNA codes: T-A-C— ...
transcription
transcription

... This allows for the transcription of the genes controlled by the operator. In negative repressible operons, (the trp operon) transcription of the genes on the operon normally takes place. Repressor proteins are produced by a regulator gene but they are unable to bind to the operator in their normal ...
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Applications of Genetic Engineering

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Chapter 13 Forensic DNA

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How do viruses differ?

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Lecture
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... DNA Profiling Each person has a unique set of fingerprints. As with a person’s fingerprint no two individuals share the same genetic makeup. This genetic makeup, which is the hereditary blueprint imparted to us by our parents, is stored in the chemical deoxyribonucleic acid (DNA), the basic molecul ...
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Bio101 Sample Questions_Exam 5 1 Flower color in snapdragons is

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Mutations - Northeast High School

... Since mutations are simply changes in DNA, in order to understand how mutations work, let’s review how DNA does its job. Your DNA contains a set of instructions for "building" a human. These instructions are inscribed in the structure of the DNA molecule through a genetic code. The sequence of these ...
Bio1A - Lec 19 slides File
Bio1A - Lec 19 slides File

... • There are 5 different snRNPs, each with its own distinct snRNA (U1, U2, U4, U5, or U6) and distinct proteins. • Spliceosome – complex of all the snRNPs that work together to mediate splicing ...
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Structure of DNA (Deoxyribonucleic acid)

... • Causes – can be spontaneous or caused by environmental influences called mutagens (such as X-rays, UV radiation, and organic chemicals (in cigarette smoke and pesticides). • Effects on organism: may have no effect, be harmful, or result in new beneficial trait • Mutations that prove beneficial mak ...
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... When performing PFGE, the circular bacterial DNA is treated with a particular restriction enzyme. These are protein structures that bind to particular sequences of normally 6 DNA letters (eg TCTAGA, but nowhere else in the DNA) and cut the DNA in two at these sites. The particular 6-letter sequences ...
1030ExamFinal
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Chromosome structure & Gene Expression
Chromosome structure & Gene Expression

... nucleosomes and are accessible to enzymes. 2. Telomeres ensure that chromosomes do not lose their termini at each round of replication: • DNA polymerase is unable to fill in an RNA primer’s length of nucleotides at the 5’ end of a new strand at chromosome tips. • This results in shortening the ends ...
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... E4. Because normal cells contain two copies of chromosome 14, one would expect that a probe would bind to complementary DNA sequences on both of these chromosomes. If a probe recognized only one of two chromosomes, this means that one of the copies of chromosome 14 has been lost, or it has suffered ...
Packet 2 - w/answers
Packet 2 - w/answers

... Amino acids have ___amino_____ and ____carboxyl______ groups. They are made unique by the “R” group that is attached to carbon “R” is like a variable in algebra class. It can have many values (structures). The Function of the amino acid is determined by the structure and conformation of the “R” grou ...
Enzymes
Enzymes

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Deoxyribozyme



Deoxyribozymes, also called DNA enzymes, DNAzymes, or catalytic DNA, are DNA oligonucleotides that are capable of catalyzing specific chemical reactions, similar to the action of other biological enzymes, such as proteins or ribozymes (enzymes composed of RNA).However, in contrast to the abundance of protein enzymes in biological systems and the discovery of biological ribozymes in the 1980s,there are no known naturally occurring deoxyribozymes.Deoxyribozymes should not be confused with DNA aptamers which are oligonucleotides that selectively bind a target ligand, but do not catalyze a subsequent chemical reaction.With the exception of ribozymes, nucleic acid molecules within cells primarily serve as storage of genetic information due to its ability to form complementary base pairs, which allows for high-fidelity copying and transfer of genetic information. In contrast, nucleic acid molecules are more limited in their catalytic ability, in comparison to protein enzymes, to just three types of interactions: hydrogen bonding, pi stacking, and metal-ion coordination. This is due to the limited number of functional groups of the nucleic acid monomers: while proteins are built from up to twenty different amino acids with various functional groups, nucleic acids are built from just four chemically similar nucleobases. In addition, DNA lacks the 2'-hydroxyl group found in RNA which limits the catalytic competency of deoxyribozymes even in comparison to ribozymes.In addition to the inherent inferiority of DNA catalytic activity, the apparent lack of naturally occurring deoxyribozymes may also be due to the primarily double-stranded conformation of DNA in biological systems which would limit its physical flexibility and ability to form tertiary structures, and so would drastically limit the ability of double-stranded DNA to act as a catalyst; though there are a few known instances of biological single-stranded DNA such as multicopy single-stranded DNA (msDNA), certain viral genomes, and the replication fork formed during DNA replication. Further structural differences between DNA and RNA may also play a role in the lack of biological deoxyribozymes, such as the additional methyl group of the DNA base thymidine compared to the RNA base uracil or the tendency of DNA to adopt the B-form helix while RNA tends to adopt the A-form helix. However, it has also been shown that DNA can form structures that RNA cannot, which suggests that, though there are differences in structures that each can form, neither is inherently more or less catalytic due to their possible structural motifs.
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