Investigation of the role of hydrogen peroxide throughout cell cycle
... which increased H2O2 molecules control mitotic progression are poorly understood. Proteins associated with the centrosome play key roles in mitotic progression in mammalian cells. The activity of Cdk1-opposing phosphatases at the centrosome must be inhibited during early mitosis to prevent premature ...
... which increased H2O2 molecules control mitotic progression are poorly understood. Proteins associated with the centrosome play key roles in mitotic progression in mammalian cells. The activity of Cdk1-opposing phosphatases at the centrosome must be inhibited during early mitosis to prevent premature ...
Practice - Univerzita Karlova v Praze
... exceeds the capacity of the citric acid cycle, the excess acetyl-CoA forms ketone bodies. This occurs in severe, uncontrolled diabetes: because the tissue cannot use glucose, they oxidize large amounts of FA instead. Although acetyl-CoA is not toxic, the mitochondrion must divert the acetyl-CoA to k ...
... exceeds the capacity of the citric acid cycle, the excess acetyl-CoA forms ketone bodies. This occurs in severe, uncontrolled diabetes: because the tissue cannot use glucose, they oxidize large amounts of FA instead. Although acetyl-CoA is not toxic, the mitochondrion must divert the acetyl-CoA to k ...
Archives and Information Retrieval
... • PIR-International Protein Sequence Database: an annotated, nonredundant and cross-referenced database of protein sequences. • PIR Alignment Database, PIR-ALN: contains sequence alignments of superfamilies, families and homology domains produced from information in the Protein Sequence Database. • ...
... • PIR-International Protein Sequence Database: an annotated, nonredundant and cross-referenced database of protein sequences. • PIR Alignment Database, PIR-ALN: contains sequence alignments of superfamilies, families and homology domains produced from information in the Protein Sequence Database. • ...
CS689-homology-modeling
... – Fiser A, Sali A. (2003). Modeller: generation and refinement of homology-based protein structure models. Methods Enz. 374:461-91. ...
... – Fiser A, Sali A. (2003). Modeller: generation and refinement of homology-based protein structure models. Methods Enz. 374:461-91. ...
Digestive enzymes of the West African giant land snail, Archachatina
... equally between the crop juice and the digestive gland. The rather low protease activity, measured by the release of peptides from casein, was found almost entirely in the digestive gland. A digestive gland location for these enzymes suggests an intracellular form of digestion of these macromolecule ...
... equally between the crop juice and the digestive gland. The rather low protease activity, measured by the release of peptides from casein, was found almost entirely in the digestive gland. A digestive gland location for these enzymes suggests an intracellular form of digestion of these macromolecule ...
Acetylcholine Receptor-associated 43K Protein Contains Covalently
... with both proteins accumulating at newly forming nervemuscle synapses at the same rate (8). Skeletal muscle 43K protein also resembles the Torpedo protein in being associated with nAchR clusters on receptor-rich membrane fragments and because redistribution of these nAchRs occurs upon its removal wi ...
... with both proteins accumulating at newly forming nervemuscle synapses at the same rate (8). Skeletal muscle 43K protein also resembles the Torpedo protein in being associated with nAchR clusters on receptor-rich membrane fragments and because redistribution of these nAchRs occurs upon its removal wi ...
Document
... – It is not easy to tell how many ligands there are in an entry, chain ids are not used consistently – It is not clearly indicated if a molecule has missing atoms, and which atoms are missing ...
... – It is not easy to tell how many ligands there are in an entry, chain ids are not used consistently – It is not clearly indicated if a molecule has missing atoms, and which atoms are missing ...
Aminosav metabolizmus IV. Aminosavak bioszintézise
... Jaundice: yellow skin and eyeballs (due to impaired liver function or blocked bile secretion bilirubin leaks into the blood) Jaundice in newborn infants: not enough glucuronyl bilirubin transferase (exposure to fluorescent lamp photochemical conversion of bilirubin) ...
... Jaundice: yellow skin and eyeballs (due to impaired liver function or blocked bile secretion bilirubin leaks into the blood) Jaundice in newborn infants: not enough glucuronyl bilirubin transferase (exposure to fluorescent lamp photochemical conversion of bilirubin) ...
Document
... of the enzymatic defect in lysine catabolism. In the brain, this makes a complex with B-6, and the brain has trouble making enough GABA. The result is seizures, because CNS function requires GABA. If these people are given very large doses of B-6 (100 mg/day), then enough is supplied to the brain to ...
... of the enzymatic defect in lysine catabolism. In the brain, this makes a complex with B-6, and the brain has trouble making enough GABA. The result is seizures, because CNS function requires GABA. If these people are given very large doses of B-6 (100 mg/day), then enough is supplied to the brain to ...
Lecture Note 6
... Introduction-The genetic information is stored in DNA present in the nucleus and transfer from one generation to other generation. DNA transfers the information to the messenger RNA (mRNA) by the process of transcription. The correct transfer of information is ensured by the complementary base pairi ...
... Introduction-The genetic information is stored in DNA present in the nucleus and transfer from one generation to other generation. DNA transfers the information to the messenger RNA (mRNA) by the process of transcription. The correct transfer of information is ensured by the complementary base pairi ...
Slides - gserianne.com
... • Vitamins B12 and C are stored in larger quantities than other water-soluble vitamins – B vitamins [know these functions] • as a group, are coenzymes used to harvest energy • Vitamin B12 is important in hematopoiesis and maintenance of myelin sheath and epithelial cells ...
... • Vitamins B12 and C are stored in larger quantities than other water-soluble vitamins – B vitamins [know these functions] • as a group, are coenzymes used to harvest energy • Vitamin B12 is important in hematopoiesis and maintenance of myelin sheath and epithelial cells ...
Peptide inhibitors of the essential cell division protein FtsA
... proteins. Expression of FtsA into Escherichia coli cells led to its accumulation in inclusion bodies. We developed a protocol permitting the purification and refolding of enzymatically active FtsA hydrolysing ATP. The purified enzyme was used to screen for peptide inhibitors of ATPase activity using ...
... proteins. Expression of FtsA into Escherichia coli cells led to its accumulation in inclusion bodies. We developed a protocol permitting the purification and refolding of enzymatically active FtsA hydrolysing ATP. The purified enzyme was used to screen for peptide inhibitors of ATPase activity using ...
Metabolic Adaptation - Washington State University
... versus protein • Amino acids and carbohydrates are at about the same oxidation state – so although the exact pathways may vary from one amino acid to another, the yield of ATP from a gram of amino acid is about the same as the yield from a gram of glucose. • However, as in the example of the fly, am ...
... versus protein • Amino acids and carbohydrates are at about the same oxidation state – so although the exact pathways may vary from one amino acid to another, the yield of ATP from a gram of amino acid is about the same as the yield from a gram of glucose. • However, as in the example of the fly, am ...
Co-metabolism of amino acids and polyfructans by
... Co-metabolism of amino acids and polyfructans by Bacteroides thetaiotaomicron in defined media. By S. Adamberg1,K. Tomson2, H. Vija3, T. Visnapuu4 & K. Adamberg1,2. 1Department of Food Processing, Tallinn University of Technology, 19086 Tallinn, Estonia; 2Competence Center of Food and Fermentation T ...
... Co-metabolism of amino acids and polyfructans by Bacteroides thetaiotaomicron in defined media. By S. Adamberg1,K. Tomson2, H. Vija3, T. Visnapuu4 & K. Adamberg1,2. 1Department of Food Processing, Tallinn University of Technology, 19086 Tallinn, Estonia; 2Competence Center of Food and Fermentation T ...
2015-2016 SMART Team Abstract Booklet.
... affinity caused by two tryptophan residues located on an α helix at the N terminus of each monomer, which provide end-capping interactions to stabilize this length in the binding pocket of the dimer. In humans, small RNAs such as siRNA or microRnas (miRNAs) regulate the expression of messenger RNA ( ...
... affinity caused by two tryptophan residues located on an α helix at the N terminus of each monomer, which provide end-capping interactions to stabilize this length in the binding pocket of the dimer. In humans, small RNAs such as siRNA or microRnas (miRNAs) regulate the expression of messenger RNA ( ...
109 y+-TYPE CATIONIC AMINO ACID TRANSPORT
... Serendipitous discovery of cDNAs encoding mCAT transporters Subtraction-differential screening (MacLeod et al. 1990b) was employed to identify cDNA clones from two closely related lymphoma cell lines (MacLeod et al. 1984, 1985) and resulted in the isolation of several novel cDNAs. One of the novel g ...
... Serendipitous discovery of cDNAs encoding mCAT transporters Subtraction-differential screening (MacLeod et al. 1990b) was employed to identify cDNA clones from two closely related lymphoma cell lines (MacLeod et al. 1984, 1985) and resulted in the isolation of several novel cDNAs. One of the novel g ...
Lecture 6
... Protein structure: Amino acids • Essential vs non-essential – Essential: NOT made by body – Nonessential: made by the body ...
... Protein structure: Amino acids • Essential vs non-essential – Essential: NOT made by body – Nonessential: made by the body ...
The Plant Cell
... Article, publication date, and citation information can be found at www.aspb.org/cgi/doi/10.1105/tpc.010279. ...
... Article, publication date, and citation information can be found at www.aspb.org/cgi/doi/10.1105/tpc.010279. ...
Proteolysis
Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Uncatalysed, the hydrolysis of peptide bonds is extremely slow, taking hundreds of years. Proteolysis is typically catalysed by cellular enzymes called proteases, but may also occur by intra-molecular digestion. Low pH or high temperatures can also cause proteolysis non-enzymatically.Proteolysis in organisms serves many purposes; for example, digestive enzymes break down proteins in food to provide amino acids for the organism, while proteolytic processing of a polypeptide chain after its synthesis may be necessary for the production of an active protein. It is also important in the regulation of some physiological and cellular processes, as well as preventing the accumulation of unwanted or abnormal proteins in cells. Consequently, dis-regulation of proteolysis can cause diseases, and is used in some venoms to damage their prey.Proteolysis is important as an analytical tool for studying proteins in the laboratory, as well as industrially, for example in food processing and stain removal.