Gonococcal outer-membrane protein PIB
... those from other serovars reveals that sequence variations occur in two discrete regions of the molecule centred on residues 1% (Varl) and 237 (Var2). A series of peptides spanning the amino acid sequence of the protein were synthesized on solid-phase supports and reacted with a panel of monoclonal ...
... those from other serovars reveals that sequence variations occur in two discrete regions of the molecule centred on residues 1% (Varl) and 237 (Var2). A series of peptides spanning the amino acid sequence of the protein were synthesized on solid-phase supports and reacted with a panel of monoclonal ...
Properties of Enzymes
... (iii) Sulfate reaction: Proteins containing sulfur amino acids (cysteine) ----give black or grey colour ...
... (iii) Sulfate reaction: Proteins containing sulfur amino acids (cysteine) ----give black or grey colour ...
Design, Synthesis, Biological Activity and Molecular Dynamics
... structurally diverse family of receptor-like and cytoplasmic enzymes expressed in all eukaryotes. Scapin G et al. [2]. indicated that large numbers of PTP genes were encoded within the human genome, including trans-membrane, receptor-like, and intracellular, non receptor-like enzymes. PTPs have posi ...
... structurally diverse family of receptor-like and cytoplasmic enzymes expressed in all eukaryotes. Scapin G et al. [2]. indicated that large numbers of PTP genes were encoded within the human genome, including trans-membrane, receptor-like, and intracellular, non receptor-like enzymes. PTPs have posi ...
File
... questions, you will look at amino acid sequence data for the β polypeptide chain of hemoglobin, often called β-globin. You will then interpret the data to hypothesize whether the monkey or the gibbon is more closely related to humans. In the alignment shown below, the letters give the sequences of t ...
... questions, you will look at amino acid sequence data for the β polypeptide chain of hemoglobin, often called β-globin. You will then interpret the data to hypothesize whether the monkey or the gibbon is more closely related to humans. In the alignment shown below, the letters give the sequences of t ...
Review Structural glycobiology: A game of snakes and ladders
... To help explore the concepts of the carbohydrate structure and recognition, let us compare carbohydrates to another flexible object, a snake. To the extent that a living snake is a flexible 3D object that is not random in its motional properties, it serves as a useful analogy for carbohydrate struct ...
... To help explore the concepts of the carbohydrate structure and recognition, let us compare carbohydrates to another flexible object, a snake. To the extent that a living snake is a flexible 3D object that is not random in its motional properties, it serves as a useful analogy for carbohydrate struct ...
Functional analysis of the human CDC5L complex
... are speci®cally removed and the coding sequences joined to form mature mRNA, which is subsequently transported into the cytoplasm for protein synthesis. Splicing takes place in the nucleus, via a two-step transesteri®cation mechanism, and this is catalysed by a large RNA±protein complex termed the s ...
... are speci®cally removed and the coding sequences joined to form mature mRNA, which is subsequently transported into the cytoplasm for protein synthesis. Splicing takes place in the nucleus, via a two-step transesteri®cation mechanism, and this is catalysed by a large RNA±protein complex termed the s ...
The role of carbohydrate in sperm
... binding to NAG moieties terminally located on ZP3 0-linked oligosaccharides (Miller et al., 1992). The involvement of terminal galactose residues in an aglycosidic linkage to penultimate sugar moieties in gamete interaction of the mouse has been questioned recently. Litscher et al. (1995) utilized o ...
... binding to NAG moieties terminally located on ZP3 0-linked oligosaccharides (Miller et al., 1992). The involvement of terminal galactose residues in an aglycosidic linkage to penultimate sugar moieties in gamete interaction of the mouse has been questioned recently. Litscher et al. (1995) utilized o ...
Poster for RCPSC mee.. - University of Alberta
... Ceramide is a sphingolipid second messenger produced in response to cellular stress via activation of sphingomyelinases. Agonists that cause cellular production of ceramide include cytokines (TNF, Fas), agents of environmental stress (heat, UV irradiation), and chemotherapeutic agents. The accumulat ...
... Ceramide is a sphingolipid second messenger produced in response to cellular stress via activation of sphingomyelinases. Agonists that cause cellular production of ceramide include cytokines (TNF, Fas), agents of environmental stress (heat, UV irradiation), and chemotherapeutic agents. The accumulat ...
Robust circadian clocks from coupled protein
... enhance the robustness of the clock (14). Here, we use mathematical modeling to study how a proteinmodification oscillator and a transcription–translation oscillator interact in growing, dividing cells. To this end, we study four models, schematically shown in Fig. 1: (i) PPC-in vitro model (Fig. 1B ...
... enhance the robustness of the clock (14). Here, we use mathematical modeling to study how a proteinmodification oscillator and a transcription–translation oscillator interact in growing, dividing cells. To this end, we study four models, schematically shown in Fig. 1: (i) PPC-in vitro model (Fig. 1B ...
(cobalamin)-dependent enzymes
... Tethered to one of the propionamide side chains of the corrin is a nucleotide-derived ‘tail’, which includes a heterocyclic base that co-ordinates cobalt from below. In animals the base is always dimethylbenzimidazole; however, bacteria use a variety of bases, including adenine. In some cases the ba ...
... Tethered to one of the propionamide side chains of the corrin is a nucleotide-derived ‘tail’, which includes a heterocyclic base that co-ordinates cobalt from below. In animals the base is always dimethylbenzimidazole; however, bacteria use a variety of bases, including adenine. In some cases the ba ...
Protein Synthesis and Words - Hewlett
... an organism. We commonly call this our “traits”. Protein molecules are large and complex, composed of hundreds of amino acid units. In each kind of protein, the amino acid units are linked together in a definite and specific sequence. The sequence of amino acids in a protein molecule is determined b ...
... an organism. We commonly call this our “traits”. Protein molecules are large and complex, composed of hundreds of amino acid units. In each kind of protein, the amino acid units are linked together in a definite and specific sequence. The sequence of amino acids in a protein molecule is determined b ...
From Structure to Function
... can be created that have both reasonably strong acids and reasonably strong bases in them, which is very difficult to achieve in free solution but very useful for general acid-base catalysis. The other type of environment is one in which the affinity of a functional group for protons has been altere ...
... can be created that have both reasonably strong acids and reasonably strong bases in them, which is very difficult to achieve in free solution but very useful for general acid-base catalysis. The other type of environment is one in which the affinity of a functional group for protons has been altere ...
HILL12_Lecture_16
... of groups that are far apart on the protein chain. One example is the protein chain in globular proteins. © 2010 Pearson Prentice Hall, Inc. ...
... of groups that are far apart on the protein chain. One example is the protein chain in globular proteins. © 2010 Pearson Prentice Hall, Inc. ...
Partial Class Notes Chapter 6-8 ENZYME#2
... What did you have for breakfast today? In the stomach gastric acid → pH 2; pepsin hydrolyzes proteins to peptides ...
... What did you have for breakfast today? In the stomach gastric acid → pH 2; pepsin hydrolyzes proteins to peptides ...
Partial Class Notes Chapter 6-8 ENZYME#2
... What did you have for breakfast today? In the stomach gastric acid → pH 2; pepsin hydrolyzes proteins to peptides ...
... What did you have for breakfast today? In the stomach gastric acid → pH 2; pepsin hydrolyzes proteins to peptides ...
Denaturation of hemoglobin in the presence of tannic acid
... Tannic acid (TA) is a natural gallotannin and is comprised of a pentagalloylglucose core esterified at all functional hydroxyl groups with gallic acid molecules (see Scheme) [4]. TA belongs to the class of hydrolysable tannins and is found in numerous plants and foods. It generally can be extracted ...
... Tannic acid (TA) is a natural gallotannin and is comprised of a pentagalloylglucose core esterified at all functional hydroxyl groups with gallic acid molecules (see Scheme) [4]. TA belongs to the class of hydrolysable tannins and is found in numerous plants and foods. It generally can be extracted ...
Lecture genes to proteins translation - IIT
... Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings ...
... Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings ...
BIOCHEMISTRY
... final products, high-energy phosphate (ATP) production, stoichiometry of b-oxidation. The specific behaviour of odd-numbered and unsaturated fatty acids. Alternative pathways for the fatty acid oxidation. Glycerol oxidation: the enzymic steps, ATP production, interrelation with glycolysis. Biosynthe ...
... final products, high-energy phosphate (ATP) production, stoichiometry of b-oxidation. The specific behaviour of odd-numbered and unsaturated fatty acids. Alternative pathways for the fatty acid oxidation. Glycerol oxidation: the enzymic steps, ATP production, interrelation with glycolysis. Biosynthe ...
Enzymes
... Basic unit of proteins: amino acids How amino acids are linked up: condensation reaction Link between amino acids: peptide bond Long chains of basic units: polypeptide Polypeptides are folded and its 3D shape is held together by weak bonds . • Weak bonds can be broken by heat and chemicals. The prot ...
... Basic unit of proteins: amino acids How amino acids are linked up: condensation reaction Link between amino acids: peptide bond Long chains of basic units: polypeptide Polypeptides are folded and its 3D shape is held together by weak bonds . • Weak bonds can be broken by heat and chemicals. The prot ...
Functional studies of the BTB domain in the Drosophila GAGA and
... This high degree of conservation suggests that D35 and G93 are essential for the domain’s normal function. To assess the functional significance of the mutations in D35 and G93 of mod(mdg4)351, we made use of the ability of the GAGA factor to activate binding site-dependent transcription in transfec ...
... This high degree of conservation suggests that D35 and G93 are essential for the domain’s normal function. To assess the functional significance of the mutations in D35 and G93 of mod(mdg4)351, we made use of the ability of the GAGA factor to activate binding site-dependent transcription in transfec ...
Proteolysis
Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Uncatalysed, the hydrolysis of peptide bonds is extremely slow, taking hundreds of years. Proteolysis is typically catalysed by cellular enzymes called proteases, but may also occur by intra-molecular digestion. Low pH or high temperatures can also cause proteolysis non-enzymatically.Proteolysis in organisms serves many purposes; for example, digestive enzymes break down proteins in food to provide amino acids for the organism, while proteolytic processing of a polypeptide chain after its synthesis may be necessary for the production of an active protein. It is also important in the regulation of some physiological and cellular processes, as well as preventing the accumulation of unwanted or abnormal proteins in cells. Consequently, dis-regulation of proteolysis can cause diseases, and is used in some venoms to damage their prey.Proteolysis is important as an analytical tool for studying proteins in the laboratory, as well as industrially, for example in food processing and stain removal.