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Macromolecules
Macromolecules

... peptide bond, and a chain of amino acids is called a polypeptide. Proteins consist of one or more polypeptides, sometimes with additional small molecules attached. The polypeptide subunits of a protein are attached by non-covalent bonds, including hydrogen bonds, electrostatic interactions, and Van ...
26.7 LABORATORY SYNTHESIS OF PEPTIDES
26.7 LABORATORY SYNTHESIS OF PEPTIDES

File - Mr. Shanks` Class
File - Mr. Shanks` Class

... The ____ dimensional____________ into alpha helices and beta-pleated sheets ______________ dimensional bends and kinks in secondary structure due to the interactions between________________ ______________________ polypeptide chains join together to make a ___________ structure ...
Protein modification in eukaryotic cell-free systems
Protein modification in eukaryotic cell-free systems

... Bioprocesses Potsdam-Golm (IZI-BB), Am Mühlenberg 13, 14476 Potsdam ...
Libraries of Specific Assays Covering Whole
Libraries of Specific Assays Covering Whole

Nervous System
Nervous System

... Translation: What it is Making a polypeptide (chain of amino acids) using an mRNA template.  mRNA = copy of gene  Every 3 letters on mRNA = codon = codes for a specific amino acid (a.a.). e.g.: the codon AUG codes for methionine (“met”)  Amino acids will be bonded together in a specific sequen ...
Intro-Cell-Physiology
Intro-Cell-Physiology

... • Transfer RNA (tRNA) - small, between 70 and 80 nucleotides, cloverleaf-shaped molecules that “transfer” amino acid molecules to the mRNA. ...
Slide 1
Slide 1

... influenced by which amino acids. Fig. 5 shows free energy calculations for association of dimer BA with dimer CF. Association of these dimers is dependent mainly on interface 3 and, as can be seen in the graph, mutation of the basic amino acids involved in salt bridges at that interface result in a ...
No Slide Title
No Slide Title

... Finding Bonds, H-bonds… • A hydrogen bond (HB) allows chunks of peptide relatively far away from each other to come close together. They are all over the place in globular proteins, so if we could identify were they are (donor and acceptor atoms), we have a huge constraint in the structure. • In a ...
Lecture 11 - Biosynthesis of Amino Acids
Lecture 11 - Biosynthesis of Amino Acids

... Enzyme has both a reductase and a nitrogenase activity. ...
Ch 1 - Composition of cells
Ch 1 - Composition of cells

... The ‘R’ group is the part of the amino acid that varies amongst the 20 amino acids ...
Biological Molecules- You are What You Eat:
Biological Molecules- You are What You Eat:

... from ____________. Another example is fructose. Disaccharides have ___ sugars. An example is ___________________ ...
James-Smaldon
James-Smaldon

... their goal, and other ants are attracted to this pheromone. Although there may be more than one path to a goal, the shortest path will accumulate the largest amount of pheromone within a given time, therefore becoming more attractive to subsequent ants. An abstract model of this principle has been u ...
TRPA1 antibody - middle region (ARP35205_P050)
TRPA1 antibody - middle region (ARP35205_P050)

Artificial Small-Molecule Peptide Synthesizer
Artificial Small-Molecule Peptide Synthesizer

... of the molecular machine ...
Detailed Objectives
Detailed Objectives

... Recognize the structures and names of substrates and products in all enzyme catalyzed reactions. Indicate the name of any enzyme catalysts and cofactors for any specific reaction. Know the general reaction type. Understand the general enzyme mechanisms and intermediate structures for those specific ...
Understanding Zika Virus Structure and Replication
Understanding Zika Virus Structure and Replication

Protein synthesis and metabolism
Protein synthesis and metabolism

... Glucose/Alanine Cycle Excess amino acids are metabolised. They are not stored for use as potential energy as this can be done more efficiently by other sources. ...
Recombinant Hepatitis B Surface Antigen, ayw
Recombinant Hepatitis B Surface Antigen, ayw

... surface proteins from the rest of the virus. The antigen is a protein that binds specifically on one of these surface proteins. It is commonly referred to as the Australian Antigen. Recombinant HbsAg ayw full length is a 24kDa protein cloned from HBV 320 genome. Description: The Saccharomyces cerevi ...
Organic Compounds
Organic Compounds

... •Hydrocarbons contain only _____________________ and __________________. Uses of Hydrocarbons •Many hydrocarbons are composed of a long polymer chain so they can be used to make ____________________ and _______________ ________________. •Many are __________________________________ so they are used f ...
aminoacyl-tRNA
aminoacyl-tRNA

... 21. The Shine-Dalgarno sequence and a nearby AUG marks the start site of translation on a bacterial mRNA • Sequence comparison of the initiator region of all bacterial mRNAs revealed that a purine-rich sequence called Shine-Dalgarno sequence is located about 10 nucleotides upstream the initiating A ...
Moringa Info. - Sita`s Super Foods
Moringa Info. - Sita`s Super Foods

... malnutrition, especially in children and breastfeeding mothers due to the effect of milk production and quality. In addition Moringa is being used to feed cattle and live stock to achieve better results in milk production and body mass. ...
Lab Dept: Coagulation Test Name: PROTEIN S, FREE
Lab Dept: Coagulation Test Name: PROTEIN S, FREE

... normal or near normal adult levels (≥50%). Total Protein S reaches adult levels by 80 – 180 days postnatal. There is evidence that functional deficiency of Protein S may occur in patients who have demonstrable Protein S antigen. Spurious low results may be obtained with plasma-based functional Prote ...
Calculating Protein Charge
Calculating Protein Charge

... • For the acidic amino acids (D and E) and the C-terminus, the form with H associated is –COOH, which is uncharged. Thus, the proportion that is in the charged form ( -COO-) is 1 minus the proportion with H associated. – Also, remember that the charged form has a negative charge, The net contributio ...
Intro Cell Physiolog..
Intro Cell Physiolog..

... • Transfer RNA (tRNA) - small, between 70 and 80 nucleotides, cloverleaf-shaped molecules that “transfer” amino acid molecules to the mRNA. ...
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Protein structure prediction



Protein structure prediction is the prediction of the three-dimensional structure of a protein from its amino acid sequence — that is, the prediction of its folding and its secondary, tertiary, and quaternary structure from its primary structure. Structure prediction is fundamentally different from the inverse problem of protein design. Protein structure prediction is one of the most important goals pursued by bioinformatics and theoretical chemistry; it is highly important in medicine (for example, in drug design) and biotechnology (for example, in the design of novel enzymes). Every two years, the performance of current methods is assessed in the CASP experiment (Critical Assessment of Techniques for Protein Structure Prediction). A continuous evaluation of protein structure prediction web servers is performed by the community project CAMEO3D.
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