IN SILICO SCREENING OF PHYTOCHEMICAL COMPOUNDS TARGETING CHILDHOOD ABSENCE EPILEPSY (CAE)
... Alpha helix Extended strand Beta turn Random coil ...
... Alpha helix Extended strand Beta turn Random coil ...
Do asparagine-linked carbohydrate chains in glycoproteins have a
... However, there may be a preference of carbohydrate for a localization at external bends of protein structure. Carbohydrate attachment has been observed to occur at positions 21, 22, 34, 62, 76 and 88 in ribonucleases (1, 2, 3, 4, 10). All these positions are localized in or close to fl-turns or to b ...
... However, there may be a preference of carbohydrate for a localization at external bends of protein structure. Carbohydrate attachment has been observed to occur at positions 21, 22, 34, 62, 76 and 88 in ribonucleases (1, 2, 3, 4, 10). All these positions are localized in or close to fl-turns or to b ...
Sequence database similarity search
... 7. Calculate pairwise alignments of two homologous segments (PA-segments, Accessions CY046942 and EF626633) of influenza A and B viruses using different algorithms: (a) Make the global optimal alignment by needle algorithm (www.ebi.ac.uk/Tools/emboss/align/); (b) Using the option of BLAST for two se ...
... 7. Calculate pairwise alignments of two homologous segments (PA-segments, Accessions CY046942 and EF626633) of influenza A and B viruses using different algorithms: (a) Make the global optimal alignment by needle algorithm (www.ebi.ac.uk/Tools/emboss/align/); (b) Using the option of BLAST for two se ...
Changes of cellular redox homeostasis and protein - LINK
... steps in vitro [1-5]. The first step is the formation of the secondary structure. In most of the cases folding starts with the formation of alpha-helices, and the formation of beta-sheets and beta-loops takes place afterward. In the end of this first step the unfolded protein is collapsed, and a mor ...
... steps in vitro [1-5]. The first step is the formation of the secondary structure. In most of the cases folding starts with the formation of alpha-helices, and the formation of beta-sheets and beta-loops takes place afterward. In the end of this first step the unfolded protein is collapsed, and a mor ...
Predicting RNA Secondary Structures
... It is possible to search databases for RNA sequences that can fold according to a specified pattern Use Patscan to search ...
... It is possible to search databases for RNA sequences that can fold according to a specified pattern Use Patscan to search ...
Study Questions for Chapter 1 – The Cell
... maximal rate (Vmax) and cannot operate any faster. The substrate concentration that results in the enzyme functioning at ½ its the maximal rate is called the Km. Km can be considered an index of the affinity an enzyme has for its substrate – a high Km indicates low affinity (i.e., it takes a lot o ...
... maximal rate (Vmax) and cannot operate any faster. The substrate concentration that results in the enzyme functioning at ½ its the maximal rate is called the Km. Km can be considered an index of the affinity an enzyme has for its substrate – a high Km indicates low affinity (i.e., it takes a lot o ...
Quantitative parameters for amino acid–base
... prediction of favorable DNA binding sites given a protein binding site, and vice versa? The experimental data suggest that this is not the case. There are examples where preferences beyond what would have been expected from the hydrogen bonding potential of the participating residues are observed. F ...
... prediction of favorable DNA binding sites given a protein binding site, and vice versa? The experimental data suggest that this is not the case. There are examples where preferences beyond what would have been expected from the hydrogen bonding potential of the participating residues are observed. F ...
FIBROUS PROTEINS
... • Collagen provides strength and structure. • Typical collagen molecule is a long, rigid structure in which three polypeptides (referred to as α-chains) are wound around one another in a rope like triple helix • The three polypeptide α-chains are held together by hydrogen bonds • Amino acid sequence ...
... • Collagen provides strength and structure. • Typical collagen molecule is a long, rigid structure in which three polypeptides (referred to as α-chains) are wound around one another in a rope like triple helix • The three polypeptide α-chains are held together by hydrogen bonds • Amino acid sequence ...
Non-specific (entropic) forces as major determinants of the structure
... somal shape and positioning results from the action of the four specific forces acting locally—for example, between one nucleosome and another, or between nucleosomes and the lamina. Monte Carlo simulations were used to demonstrate that entropic forces acting alone can position and shape self-avoidi ...
... somal shape and positioning results from the action of the four specific forces acting locally—for example, between one nucleosome and another, or between nucleosomes and the lamina. Monte Carlo simulations were used to demonstrate that entropic forces acting alone can position and shape self-avoidi ...
PDF version of paper
... TEXshade, a LATEX package provides an ideal solution of displaying the key changes in DNA (4 letters: A, T, G and C) or protein (20 different amino acids, indicated by unique single letters) sequences with great control. Other programs do exist that provide a way to display sequence similarities in ...
... TEXshade, a LATEX package provides an ideal solution of displaying the key changes in DNA (4 letters: A, T, G and C) or protein (20 different amino acids, indicated by unique single letters) sequences with great control. Other programs do exist that provide a way to display sequence similarities in ...
Our work was originally motivated my collaboration with Drs
... DNA sequence corresponding to a known peptide sequence is spliced into the phage DNA. When this spliced sequence is transcribed and translated it produces a 9-mer polypeptide of the form $CX_7C$ (here, $C$ = cysteine, $X$ = any amino acid) which is attached to one of the phage's coat proteins. Conce ...
... DNA sequence corresponding to a known peptide sequence is spliced into the phage DNA. When this spliced sequence is transcribed and translated it produces a 9-mer polypeptide of the form $CX_7C$ (here, $C$ = cysteine, $X$ = any amino acid) which is attached to one of the phage's coat proteins. Conce ...
medical management: portosystemic vascular anomalies (psva)
... done at 7 to 10 day intervals. If all goes well (HE controlled, maintained weight, no ammonium biurates) additional protein supplements may be explored. This is done using 0.3 gm/protein/kg BWt additional protein support, with follow-up sequential assessments to ensure patient benefit and tolerance. ...
... done at 7 to 10 day intervals. If all goes well (HE controlled, maintained weight, no ammonium biurates) additional protein supplements may be explored. This is done using 0.3 gm/protein/kg BWt additional protein support, with follow-up sequential assessments to ensure patient benefit and tolerance. ...
... Choice A: Describe the events that occur during elongation of the growing polypeptide chain. Choice B: Describe the events that occur during termination of protein synthesis. Choice C: Although both AAA and AAG code for lysine (Lys) there is only one tRNALYS. Briefly explain how a single tRNA can re ...
Novel Biomolecular Structural and Functional Information from
... bound myoglobin active site, with a unique dual hydrogen bonding mode, which produced data that are in excellent accord with various experimental spectroscopic results and stabilities. Another important topic is on direct HNO probes for in vivo applications. Recent breakthr ...
... bound myoglobin active site, with a unique dual hydrogen bonding mode, which produced data that are in excellent accord with various experimental spectroscopic results and stabilities. Another important topic is on direct HNO probes for in vivo applications. Recent breakthr ...
Oxidative Stress and Repair
... Oxidation of pyrimidine and purine bases leads to DNA damage. Oxidation of methionine and cysteine residues can lead to protein damage and aggregation. DNA damage is repaired by several enzymes in the Base Excision Repair pathway (BER). Proteins are repaired by methionine sulfoxide reductases (MsrA, ...
... Oxidation of pyrimidine and purine bases leads to DNA damage. Oxidation of methionine and cysteine residues can lead to protein damage and aggregation. DNA damage is repaired by several enzymes in the Base Excision Repair pathway (BER). Proteins are repaired by methionine sulfoxide reductases (MsrA, ...
P Natl Acad Sci Usa 1994 Wild
... of a number of research efforts (4-9). Reports have described a leucine zipper-like (coiled-coil) motif located in the transmembrane protein of HIV-1 (10, 11). This domain is highly conserved among HIV-1 isolates and analogous regions have been identified in the transmembrane proteins of a number of ...
... of a number of research efforts (4-9). Reports have described a leucine zipper-like (coiled-coil) motif located in the transmembrane protein of HIV-1 (10, 11). This domain is highly conserved among HIV-1 isolates and analogous regions have been identified in the transmembrane proteins of a number of ...
Structural Influences: Cholesterol, Drug, and Proton Binding to Full
... have found that the TM domain resonances are stronger than resonances from the terminal regions of the protein. Consequently, in general it can be anticipated that our observed cross peaks would be dominated by magnetization transfer within the conductance domain. In addition, the only ambiguities f ...
... have found that the TM domain resonances are stronger than resonances from the terminal regions of the protein. Consequently, in general it can be anticipated that our observed cross peaks would be dominated by magnetization transfer within the conductance domain. In addition, the only ambiguities f ...
Quiz 2 Review Sheet
... 48.5 Know sickle-cell anemia example really well. You should be able to use this example to convince to me that mutations can be both positive and negative. Really well! ...
... 48.5 Know sickle-cell anemia example really well. You should be able to use this example to convince to me that mutations can be both positive and negative. Really well! ...
Protein Quality Control Mechanisms and Protein
... prolamine protein bodies rather than bound to their surface, possibly suggesting that this chaperone plays different functions in the biogenesis of protein bodies in different species (Levanony et al., 1992). It is also worth noting that proteins with similar primary structure may be differently rec ...
... prolamine protein bodies rather than bound to their surface, possibly suggesting that this chaperone plays different functions in the biogenesis of protein bodies in different species (Levanony et al., 1992). It is also worth noting that proteins with similar primary structure may be differently rec ...
AminoAcidMetabolismFIN2011
... • The positive heterotropic activator, Nacetylglutamate, is required for activity. • Brings one C atom and one N atom into the urea cycle as a carbamoyl group. • Catalyzes the critical step in removing NH4+ from the blood. ...
... • The positive heterotropic activator, Nacetylglutamate, is required for activity. • Brings one C atom and one N atom into the urea cycle as a carbamoyl group. • Catalyzes the critical step in removing NH4+ from the blood. ...
Biology 410 - KSU Web Home
... liposome system. How would you do this? In your answer, be sure to tell how you would get the protein out of the salivary gland membranes and how you would put it into liposomes. Also (and this is a critical part to the answer!), you must tell me how you will know if the protein in the liposomes is ...
... liposome system. How would you do this? In your answer, be sure to tell how you would get the protein out of the salivary gland membranes and how you would put it into liposomes. Also (and this is a critical part to the answer!), you must tell me how you will know if the protein in the liposomes is ...
4 Titration Curve of an Amino Acid
... addition to the ionizable protons of the α-COOH and α-NH3 groups, they also have a dissociable proton in their R group. Although triprotic amino acids can exist as zwitterions, under physiological conditions these amino acids will be charged. If the net charge under physiological conditions is negat ...
... addition to the ionizable protons of the α-COOH and α-NH3 groups, they also have a dissociable proton in their R group. Although triprotic amino acids can exist as zwitterions, under physiological conditions these amino acids will be charged. If the net charge under physiological conditions is negat ...
Biol 115 DNA, the Thread of Life
... The amino acids specified by each mRNA codon. Multiple codons can code for the same amino acid. The codons are written 5' to 3', as they appear in the mRNA. AUG is an initiation codon; UAA, UAG, and UGA are termination (stop) codons. Biol115_2014_Lecture 7 ...
... The amino acids specified by each mRNA codon. Multiple codons can code for the same amino acid. The codons are written 5' to 3', as they appear in the mRNA. AUG is an initiation codon; UAA, UAG, and UGA are termination (stop) codons. Biol115_2014_Lecture 7 ...
Protein structure prediction
Protein structure prediction is the prediction of the three-dimensional structure of a protein from its amino acid sequence — that is, the prediction of its folding and its secondary, tertiary, and quaternary structure from its primary structure. Structure prediction is fundamentally different from the inverse problem of protein design. Protein structure prediction is one of the most important goals pursued by bioinformatics and theoretical chemistry; it is highly important in medicine (for example, in drug design) and biotechnology (for example, in the design of novel enzymes). Every two years, the performance of current methods is assessed in the CASP experiment (Critical Assessment of Techniques for Protein Structure Prediction). A continuous evaluation of protein structure prediction web servers is performed by the community project CAMEO3D.