The Role of the N-Terminal Domains of Bacterial Initiator DnaA in
... number of initiation complexes per chromosome, initiation complex composition, protein-protein and protein-DNA interactions between initiation complex components, and check-point steps vary among organisms, with greater differences occurring among more unrelated taxonomic groups [3,4]. It is assumed ...
... number of initiation complexes per chromosome, initiation complex composition, protein-protein and protein-DNA interactions between initiation complex components, and check-point steps vary among organisms, with greater differences occurring among more unrelated taxonomic groups [3,4]. It is assumed ...
Lung fluid restriction affects growth but not airway branching of
... configuration of the genome leading to alterations in accessibility of transcriptional binding sites on the growth factor promoters. However, distending forces may also affect RNA stability and protein translation. Recently, Singhvi et al. (1994) have demonstrated that limiting cell extension reduce ...
... configuration of the genome leading to alterations in accessibility of transcriptional binding sites on the growth factor promoters. However, distending forces may also affect RNA stability and protein translation. Recently, Singhvi et al. (1994) have demonstrated that limiting cell extension reduce ...
Dissection of molecular interactions of replication protein A in
... My studies showed RPA binds different locations along ssDNA and that generally RPA does not undergo global changes in conformation when bound to ssDNA. However, with a subset of label locations, some RPA-DNA complexes showed rare changes in conformation. These observations were most consistent with ...
... My studies showed RPA binds different locations along ssDNA and that generally RPA does not undergo global changes in conformation when bound to ssDNA. However, with a subset of label locations, some RPA-DNA complexes showed rare changes in conformation. These observations were most consistent with ...
Purification and characterization of a novel caffeine oxidase from
... chronic ingestion of caffeine and/or its byproduct 8chlorocaffeine (produced during chlorination) can have adverse effects on the physiological systems (Gould and Hay, 1982; White and Rasmussen, 1998). Decaffeination is usually performed by physico-chemical treatments, such as water diffusion (Feldm ...
... chronic ingestion of caffeine and/or its byproduct 8chlorocaffeine (produced during chlorination) can have adverse effects on the physiological systems (Gould and Hay, 1982; White and Rasmussen, 1998). Decaffeination is usually performed by physico-chemical treatments, such as water diffusion (Feldm ...
Renal tubular Sirt1 attenuates diabetic albuminuria by
... The β-catenin/Snail pathway plays a role in the pathogenesis of albuminuria27, and Claudin-1 reportedly activates the β-catenin/Snail pathway in colon epithelial cells28. Thus, we examined whether Claudin-1 activated the β-catenin/Snail pathway in podocytes. Transfer of Claudin-1 gene upregulated bo ...
... The β-catenin/Snail pathway plays a role in the pathogenesis of albuminuria27, and Claudin-1 reportedly activates the β-catenin/Snail pathway in colon epithelial cells28. Thus, we examined whether Claudin-1 activated the β-catenin/Snail pathway in podocytes. Transfer of Claudin-1 gene upregulated bo ...
A mutation mimicking ligandinduced conformational change yields a
... ligands or vehicle (ethanol) for 24 h. CAT levels were determined by ELISA. Results are expressed as fold induction of basal reporter gene activity and represent the mean ⫾ SEM of three to six independent experiments. In (A), Kds for 9c-RA were determined by Scatchard analysis; EC50 values correspon ...
... ligands or vehicle (ethanol) for 24 h. CAT levels were determined by ELISA. Results are expressed as fold induction of basal reporter gene activity and represent the mean ⫾ SEM of three to six independent experiments. In (A), Kds for 9c-RA were determined by Scatchard analysis; EC50 values correspon ...
Reduced Activity of Antioxidant Machinery Is
... compared with the purified cellulase, resulted in increased levels of intracellular (⫹77%) and extracellular (⫹100%) O2.⫺ and intracellular (⫹40%) and extracellular (⫹71%) H2O2 in tobacco protoplasts (Table I). Also, in grapevine protoplasts, the O2.⫺ level increased intracellularly (⫹14%) and extra ...
... compared with the purified cellulase, resulted in increased levels of intracellular (⫹77%) and extracellular (⫹100%) O2.⫺ and intracellular (⫹40%) and extracellular (⫹71%) H2O2 in tobacco protoplasts (Table I). Also, in grapevine protoplasts, the O2.⫺ level increased intracellularly (⫹14%) and extra ...
Hi, Cill
... idea to proceed slowly at first if glutathione has been depleted for an extended period of time (months to years), because toxins and infections may have been allowed to build up in the absence of sufficient glutathione to keep them under control. If glutathione is then brought up rapidly, the mobil ...
... idea to proceed slowly at first if glutathione has been depleted for an extended period of time (months to years), because toxins and infections may have been allowed to build up in the absence of sufficient glutathione to keep them under control. If glutathione is then brought up rapidly, the mobil ...
Complex Degradation Processes Lead to Non
... framework, into which one can incorporate additional molecular details about specific degradation mechanisms. Experimentally, the decay patterns are often determined by the measurement of the decaying average amount of each mRNA species at steady state expression, in a cell culture after the interru ...
... framework, into which one can incorporate additional molecular details about specific degradation mechanisms. Experimentally, the decay patterns are often determined by the measurement of the decaying average amount of each mRNA species at steady state expression, in a cell culture after the interru ...
Weak-base amines inhibit the anterograde-to
... Acidotropic weak-base amines were used to investigate the role of acidic compartments in the pathway of aterograde-toretrograde conversion of axonally transported vesicles in axon terminals. A local concentrated population of nascent axon tips was produced by transecting the rat sciatic nerve in sit ...
... Acidotropic weak-base amines were used to investigate the role of acidic compartments in the pathway of aterograde-toretrograde conversion of axonally transported vesicles in axon terminals. A local concentrated population of nascent axon tips was produced by transecting the rat sciatic nerve in sit ...
... Lewisb (Leb), and sialic acid-binding adhesin, which binds sialylated LewisX (LeX). There are many other H. pylori adhesion molecules, such as hemagglutinin, which interacts with sialic acid exposed on human tissues, and lesscharacterized adhesion molecules that interact with host extracellular matr ...
Abscisic Acid Coordinates Nod Factor and Cytokinin Signaling
... Oscillations of calcium (calcium spiking) act as a secondary messenger in the Nod factor signal transduction pathway (Ehrhardt et al., 1996; Oldroyd and Downie, 2004). To better understand ABA’s affect on Nod factor signal transduction, we determined the role of ABA on the regulation of calcium spik ...
... Oscillations of calcium (calcium spiking) act as a secondary messenger in the Nod factor signal transduction pathway (Ehrhardt et al., 1996; Oldroyd and Downie, 2004). To better understand ABA’s affect on Nod factor signal transduction, we determined the role of ABA on the regulation of calcium spik ...
Pathology of The Parathyroid Glands
... Parathyroid carcinoma is seen in 0.5 to 2 percent of cases hyperparathyroidism. There appears to be an equal sex predilection. Patients with parathyroid carcinoma are younger than those with adenoma, and usually present with profound hypercalcemia, and/or its clinical consequences. The initial clini ...
... Parathyroid carcinoma is seen in 0.5 to 2 percent of cases hyperparathyroidism. There appears to be an equal sex predilection. Patients with parathyroid carcinoma are younger than those with adenoma, and usually present with profound hypercalcemia, and/or its clinical consequences. The initial clini ...
MDM2 inhibit p300-mediated p53 acetylation and activation by
... MDM2 inhibits p300-mediated p53 acetylation and activation by forming a ternary complex with the two protein Eric Kobet , Xiaoya Zeng , Yong Zhu , David Keller , and Hua Lu ...
... MDM2 inhibits p300-mediated p53 acetylation and activation by forming a ternary complex with the two protein Eric Kobet , Xiaoya Zeng , Yong Zhu , David Keller , and Hua Lu ...
Nkx2-5 mutation causes anatomic hypoplasia of the cardiac
... Endothelin and neuregulin-1 in the chick and mouse, respectively, may induce recruitment into the peripheral Purkinje system (5, 6), but little else is known about the mechanisms that govern the development of the conduction system. To our knowledge, no diseases have yet been reported to perturb spe ...
... Endothelin and neuregulin-1 in the chick and mouse, respectively, may induce recruitment into the peripheral Purkinje system (5, 6), but little else is known about the mechanisms that govern the development of the conduction system. To our knowledge, no diseases have yet been reported to perturb spe ...
Supplementary Table 1
... play a role in numerous cellular processes, especially those involving DNA or RNAmediated reactions. For example, VIP1 and VirE2 enable uptake of the agrobacterium genome into the host nucleus. Subsequently, VirF, an F-box protein, promotes the degradation of VirE2 and VIP1, exposing the genome so t ...
... play a role in numerous cellular processes, especially those involving DNA or RNAmediated reactions. For example, VIP1 and VirE2 enable uptake of the agrobacterium genome into the host nucleus. Subsequently, VirF, an F-box protein, promotes the degradation of VirE2 and VIP1, exposing the genome so t ...
Cohesin`s ATPase Activity Couples Cohesin Loading
... MAU2 [9, 10]. Experiments in yeast have shown that cohesin complexes deficient in ATP hydrolysis associate with chromatin in a Scc2-dependent but transient manner [11], whereas topological loading of cohesin onto DNA in vitro is stimulated by the loading complex and depends on cohesin’s ATPase activ ...
... MAU2 [9, 10]. Experiments in yeast have shown that cohesin complexes deficient in ATP hydrolysis associate with chromatin in a Scc2-dependent but transient manner [11], whereas topological loading of cohesin onto DNA in vitro is stimulated by the loading complex and depends on cohesin’s ATPase activ ...
store-operated calcium channels
... assortment of basic biological processes such as secretion, gene transcription, and modulation of enzymatic activity and motility. Because they are not voltage dependent, SOCs can conduct Ca2⫹ at negative membrane potentials at which depolarization-sensitive channels [e.g., voltage-gated Ca2⫹ (CaV) ...
... assortment of basic biological processes such as secretion, gene transcription, and modulation of enzymatic activity and motility. Because they are not voltage dependent, SOCs can conduct Ca2⫹ at negative membrane potentials at which depolarization-sensitive channels [e.g., voltage-gated Ca2⫹ (CaV) ...
Auxin: The Growth Hormone - Roberto Cezar | Fisiologista Vegetal
... plants have been derived from similar studies in animals. In animals the chemical messengers that mediate intercellular communication are called hormones. Hormones interact with specific cellular proteins called receptors. Most animal hormones are synthesized and secreted in one part of the body and ...
... plants have been derived from similar studies in animals. In animals the chemical messengers that mediate intercellular communication are called hormones. Hormones interact with specific cellular proteins called receptors. Most animal hormones are synthesized and secreted in one part of the body and ...
Lipopolysaccharide-bound structure of the antimicrobial peptide
... focus on identification of natural AMPs, and over 1300 AMPs have been isolated from a variety of organisms. AMPs are classified based on their amino acid composition or structure as β-sheet, α-helical, loop, and extended peptides. Cecropins, histatins, defensins, and cathelicidins are well-known AMP ...
... focus on identification of natural AMPs, and over 1300 AMPs have been isolated from a variety of organisms. AMPs are classified based on their amino acid composition or structure as β-sheet, α-helical, loop, and extended peptides. Cecropins, histatins, defensins, and cathelicidins are well-known AMP ...
Paraxial mesoderm specifies zebrafish primary motoneuron subtype
... CaP-like axon and initiates expression of islet2. However, when MiP is transplanted in the same way just 1 hour before axogenesis, it remains committed to its original fate, extends a MiP-like axon and does not express islet2 (Appel et al., 1995; Eisen, 1991). Furthermore, PMN specification and deve ...
... CaP-like axon and initiates expression of islet2. However, when MiP is transplanted in the same way just 1 hour before axogenesis, it remains committed to its original fate, extends a MiP-like axon and does not express islet2 (Appel et al., 1995; Eisen, 1991). Furthermore, PMN specification and deve ...
Bactericidal/Permeability-Increasing Protein Release in Whole
... and SDZ MRL 953 at 10 j.Lg/mL to exert this effect. Furthermore, at submicromolar concentrations, FMLP strongly activated PMNL to release BPI. In addition, two products of grampositive bacteria were tested. The cell wall component LTA induced release of BPI, although not as potently as the component ...
... and SDZ MRL 953 at 10 j.Lg/mL to exert this effect. Furthermore, at submicromolar concentrations, FMLP strongly activated PMNL to release BPI. In addition, two products of grampositive bacteria were tested. The cell wall component LTA induced release of BPI, although not as potently as the component ...
Brock_Charter_Christopher_2011
... functional role of these receptors was examined, and it was shown that normal molluscan development was altered, to varying degrees, by the presence of various RXR and RAR agonists or antagonists. The resulting disruptions in embryogenesis ranged from eye and shell defects, to complete lysis of the ...
... functional role of these receptors was examined, and it was shown that normal molluscan development was altered, to varying degrees, by the presence of various RXR and RAR agonists or antagonists. The resulting disruptions in embryogenesis ranged from eye and shell defects, to complete lysis of the ...