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Reconstruction of the nigrostriatal dopamine pathway in the adult
Reconstruction of the nigrostriatal dopamine pathway in the adult

Inferring a dual-stream model of mentalizing from associative white
Inferring a dual-stream model of mentalizing from associative white

... for basic cognitive processes is never surgically removed, despite lesion invasion (Ius et al., 2011). Consequently, analysis of patients with diffuse low-grade glioma constitutes a unique opportunity to gain a better understanding of the functional counterpart of surgical excisions (at the cortical ...
Gender Differences in Human Brain: A Review
Gender Differences in Human Brain: A Review

... grams more of brain tissue. Women have a more developed neuropil, or the space between cell bodies, which contains synapses, dendrites and axons. This may explain why women are more prone to dementia (such as Alzheimer's disease) than men, because although both may lose the same number of neurons du ...
ON THE ORIGIN OF EUKARIOTES WHEN CELLS GOT COMPLEX
ON THE ORIGIN OF EUKARIOTES WHEN CELLS GOT COMPLEX

... bring Drosophila neuroscience research to scientists in West Africa. The workshop was held at the Kwame Nkrumah University of Science and Technology (KNUST) in Kumasi, Ghana in December 2015. The idea was born in the hustle and bustle of the Louis lab at the CRG, and developed into a full-fledged pl ...
Golgi: a life in science - Oxford Academic
Golgi: a life in science - Oxford Academic

... In 1906, the professors of the Karolinska Institute had a problem; who should get the Nobel Prize in Physiology or Medicine? In the previous 25 years, understanding of the structure of the brain and spinal cord had greatly increased. The nerve cell, or neuron, had been identified as the fundamental ...
A Symmetric Approach Elucidates Multisensory Information Integration
A Symmetric Approach Elucidates Multisensory Information Integration

... Continuous mappings from object spaces to feature spaces lead to various variants of the Borsuk-Ulam Theorem [13,31,32]. Antipodal points are points opposite each other on a Sn sphere [33]. There are natural ties between Borsuk’s result for antipodes and mappings called homotopies. In fact, the earl ...
Integrating Optogenetic and Pharmacological Approaches to Study
Integrating Optogenetic and Pharmacological Approaches to Study

... consistent with the temporal dynamics of endogenous neural activity, represents the second key strength of optogenetic manipulations. Although neural circuit function is temporally modulated over a range of time intervals, the moment-to-moment processing of sensory cues and adaptive behavioral respo ...
Neural Compensations After Lesion of the Cerebral Cortex
Neural Compensations After Lesion of the Cerebral Cortex

... compensate for injury to the cerebral cortex. One of the obstacles to compensation, however, is that functions are relatively localized in the cerebral cortex. Indeed, during the 100 years that followed Broca’s first paper in 1861 showing cerebral localization of language, the concept of functional ...
BRAIN Response inhibition and serotonin in autism: depletion
BRAIN Response inhibition and serotonin in autism: depletion

... during facial emotion processing (Daly et al., 2012). However, to our knowledge, no one has investigated the modulatory effect of serotonin on inhibitory neural activity in individuals with ASD. Also nobody has related clinical severity of RSRB symptoms to differences in brain response to serotonin. ...
The neuronal ceroid lipofuscinoses: the same, but different?
The neuronal ceroid lipofuscinoses: the same, but different?

... Fortunately, revealing the genes defective in most forms of NCL has also made it possible to generate a series of genetically modified mouse models and to identify spontaneously occurring mutants which bear mutations in these genes [17]. In addition to mice, these models include a diverse series of ...
Proceedings of 2014 BMI the Third International Conference on
Proceedings of 2014 BMI the Third International Conference on

... Tianzi Jiang is Professor of Brain Imaging and Cognitive Disorders, Institute Automation of Chinese Academy of Sciences (CASIA), and Professor of Queensland Brain Institute, University of Queensland. He is the Director of Brainnetome Center of CASIA and the Chinese Director of the Sino-French Labora ...
Neurosteroids: Expression of Steroidogenic Enzymes and
Neurosteroids: Expression of Steroidogenic Enzymes and

... system as unconjugated steroids, sulfated esters of steroids, or fatty acid esters of steroids (Jo et al., 1989). These various forms of steroids are involved in the control of metabolic, behavioral, and psychical processes including cognition, stress, anxiety, and sleep (Majewska, 1992; Baulieu and ...
the cognitive neuroscience of motivation and learning
the cognitive neuroscience of motivation and learning

... more cognitive understanding of goal-directed behavior. In particular, we draw on operational distinctions elucidated in the animal behavioral literature in order to suggest that while reinforcement learning theories of dopamine may provide a good account of behavior known as habitual or stimulus-re ...
from ups
from ups

Chapter 12 PowerPoint - Hillsborough Community College
Chapter 12 PowerPoint - Hillsborough Community College

... • Electroencephalogram (EEG) records electrical activity that accompanies brain function – Used for diagnosing epilepsy and sleep disorders – Localizes lesions, tumors, infarcts, infections, abscesses – Used in research and also to determine brain death – Electrodes placed on scalp measure electrica ...
CEREBRAL CORTEX - Oxford Academic
CEREBRAL CORTEX - Oxford Academic

... provoke a debate, and few would argue that the effects of age on brain structure are uniform and diffuse. What remains unsettled are more complex questions regarding specific patterns of cerebral aging and their underlying mechanisms. It is unclear whether coherent common patterns of localized brain ...
Role of neurons and glia in the CNS actions of the renin
Role of neurons and glia in the CNS actions of the renin

... Importantly these highly specific and sensitive in situ hybridization and genetic techniques for the localization of ANG II receptors have not yet been extended to models of cardiovascular pathophysiology, in which it is possible that AT1R and/or AT2R may become expressed on the non-neuronal cell ty ...
Mirror neurons and the social nature of language
Mirror neurons and the social nature of language

... which the brain/body system models its interactions with the world (Gallese, 2001, 2003a, 2003b, 2005a, 2005b, 2006). The discovery of mirror neurons has changed our views on the relations among action perception and cognition, and has boosted a renewed interest in the neuroscientific investigation ...
Summary
Summary

... that the return of oogenesis occurs in parallel to the progress of the reconstruction of the neurosecretory system of the regenerating brains. In our preliminary study we showed that the amputation of the first six head segments of D. veneta resulted in a temporary inhibition of cocoon production, w ...
Forward Prediction in the Posterior Parietal Cortex and Dynamic
Forward Prediction in the Posterior Parietal Cortex and Dynamic

... sensory feedback control are feasible for capturing moving objects. Clinically viable BMI systems that enable real-time interactions with dynamic environments demand translation of predictive neural activity into desired motor goals to guide ballistic movements, as in natural interception (Figure 2A ...
S - 7473-2390-3942 Accountability in United States
S - 7473-2390-3942 Accountability in United States

... of interest in animal models, the study remains unexplored in human populations due to the numerous challenges experienced in studying human models. The amygdale is also an area of interest in evaluating the impact of prenatal stress in fetal neurobehavioral development. The amygdale is a small port ...
5-28-2007
5-28-2007

... limbs of the diagonal band, and in the sublenticular basal forebrain can be easily delineated in histological sections stained with a modified Gallyas’s silver method for cell bodies (Merker, 1983). This method has been proven as an excellent marker for cytoarchitectonic studies (Uylings et al., 19 ...
uncorrected page page page proofs
uncorrected page page page proofs

... cerebrospinal fluid that flows between them. Despite its fragile look and feel, the brain is the most complex organ in the body and perhaps the most complex natural or artificial structure in the known universe. Its remarkable complexity is largely invisible to the naked eye. You cannot see that it ...
cHaPter 3
cHaPter 3

... liquid (cerebrospinal fluid) that circulates between the membranes. This provides a cushion against knocks to the head, protecting the brain from injury unless the knock is quite hard. The many arteries you can see carry nutrients and oxygen-rich blood throughout the brain. Without this blood, brain ...
Evidence for a distributed hierarchy of action
Evidence for a distributed hierarchy of action

... prehension remains an important experimental paradigm for demonstrating how behavior is shaped in anticipation of future motor outcomes. During a reach and grasp, the arm, hand and digits move toward the desired object in a highly structured behavioral pattern, with kinematic features reflecting the ...
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Neuroinformatics

Neuroinformatics is a research field concerned with the organization of neuroscience data by the application of computational models and analytical tools. These areas of research are important for the integration and analysis of increasingly large-volume, high-dimensional, and fine-grain experimental data. Neuroinformaticians provide computational tools, mathematical models, and create interoperable databases for clinicians and research scientists. Neuroscience is a heterogeneous field, consisting of many and various sub-disciplines (e.g., Cognitive Psychology, Behavioral Neuroscience, and Behavioral Genetics). In order for our understanding of the brain to continue to deepen, it is necessary that these sub-disciplines are able to share data and findings in a meaningful way; Neuroinformaticians facilitate this.Neuroinformatics stands at the intersection of neuroscience and information science. Other fields, like genomics, have demonstrated the effectiveness of freely-distributed databases and the application of theoretical and computational models for solving complex problems. In Neuroinformatics, such facilities allow researchers to more easily quantitatively confirm their working theories by computational modeling. Additionally, neuroinformatics fosters collaborative research—an important fact that facilitates the field's interest in studying the multi-level complexity of the brain.There are three main directions where neuroinformatics has to be applied: the development of tools and databases for management and sharing of neuroscience data at all levels of analysis, the development of tools for analyzing and modeling neuroscience data, the development of computational models of the nervous system and neural processes.In the recent decade, as vast amounts of diverse data about the brain were gathered by many research groups, the problem was raised of how to integrate the data from thousands of publications in order to enable efficient tools for further research. The biological and neuroscience data are highly interconnected and complex, and by itself, integration represents a great challenge for scientists.Combining informatics research and brain research provides benefits for both fields of science. On one hand, informatics facilitates brain data processing and data handling, by providing new electronic and software technologies for arranging databases, modeling and communication in brain research. On the other hand, enhanced discoveries in the field of neuroscience will invoke the development of new methods in information technologies (IT).
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