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Lab - Recombinant DNA Simulation
Lab - Recombinant DNA Simulation

... Genetic engineering is possible because of special enzymes that cut DNA. These enzymes are called restriction enzymes. Restriction enzymes are proteins produced by bacteria used to prevent (or restrict) the invasion of viruses. They act as “DNA scissors”, cutting viral DNA into pieces so that it can ...
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Biochemistry - Fort Thomas Independent Schools
Biochemistry - Fort Thomas Independent Schools

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Chapter 22 (Part 1) - University of Nevada, Reno
Chapter 22 (Part 1) - University of Nevada, Reno

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... • The stop codon is one that does not code for an amino acid and that terminates the translation process • the polypeptide is released and the mRNA fragments return to the nucleus • These nucleotides are recycled and used for RNA and DNA synthesis • tRNA also is returned to its free state and attach ...
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... Nucleic acids are polymers of nucleotides. Each nucleotide consists of a nitrogenous base, a sugar, and a phosphate group. In the case of DNA, the nucleotides can be guanine, adenine, thymine or cytosine, and, hence, there are four possible nucleotides. The sequence of nucleotides, in some chains of ...
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... • Germ-line mutations are changes in the DNA of germ (reproductive) cells and may be passed to offspring. • Somatic mutations are changes in the DNA of an organism’s somatic tissue cells and cannot be passed to offspring. • Lethal mutations, when expressed, result in the death of the microorganism. ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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