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HiPer® Plasmid DNA Cloning Teaching Kit
HiPer® Plasmid DNA Cloning Teaching Kit

... two DNA fragments (having blunt or overhanging, complementary, 'sticky' ends) by the help of an enzyme named as ligase. DNA ligase forms a phosphodiester bond between the 3’ hydroxyl of one nucleotide and the 5’ phosphate of another. Ligation can be directional or non-directional based upon the rest ...
NABP1, a novel RORγ-regulated gene encoding a single
NABP1, a novel RORγ-regulated gene encoding a single

... full-length NABP1 and NABP1N (amino acids 146–198) respectively, into the EcoRI and BamHI sites of pMAL-C2X (New England BioLabs, Ipswich, MA, U.S.A.). NABP1 was amplified with the sense, 5 -GAGAATTCATGCACGGGGTCAACGAC-3 , and antisense, 5 -GTGGATCCTCATCATTTAAAGGCTCTCCTC-3 , primers, NABP1N was ...
Close relationship between non-viral retroposons in Drosophila
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... Cx 2 Cx 4 Hx 4 C motif, and two adjacent imperfect ones (fig. 7a) are found within G-orfl, a 241 amino acid long orf that partially overlaps G-orf2 (figs. 2 and 3). In fig. 7b the G-orfl region encompassing the cysteine-rich motifs is aligned with the homologous regions in F-orf 1 and Iorfl. The hom ...
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... B) the peptide bonds linking amino acids differ from protein to protein. C) the sequence of amino acids in the polypeptide chain differs from protein to protein. D) each protein contains its own unique sequence of sugar molecules. E) the number of nucleotides found in each protein varies from molecu ...
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ch_02 - HCC Learning Web

... cells and viruses. These differ primarily in the structure of their monomers, which are called nucleotides. Each nucleotide consists of phosphate, a pentose sugar (deoxyribose or ribose), and one of five cyclic nitrogenous bases: adenine (A), guanine (G), cytosine (C), thymine (T), uracil (U). DNA c ...
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Framework Evidence of Learning FEOL

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...  Failure of homologous to separate during Anaphase I (resulting in four affected daughter cells)  Failure of sister chromatids to separate during Anaphase II (resulting in two affected daughter cells) One parental gamete is normal and has a single copy of chromosome 21 but the other parental gamet ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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