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Conservation of the metabolomic response to starvation across two divergent microbes.
Conservation of the metabolomic response to starvation across two divergent microbes.

... and tryptophan follow a common pathway up to the key intermediate chorismate, which contains no nitrogen. Chorismate then can acquire nitrogen from glutamine to follow the tryptophan pathway or, alternatively, can form the nitrogen-free precursor to phenylalanine and tyrosine, prephenate. Prephenate ...
BIOC*4540 ENZYMOLOGY Winter 2015
BIOC*4540 ENZYMOLOGY Winter 2015

... important to remember that anything that you include or say during your presentation is open to  questions from the audience and so you should ensure that you fully understand it.  Each student  in the class will complete an evaluation of the seminars, except for their own presentations (no  marks g ...
Respiratory System Jeopardy
Respiratory System Jeopardy

... This is a disease where the air sacs are no longer able to expand and ...
Fatty acid desaturation and chain elongation in eukaryotes
Fatty acid desaturation and chain elongation in eukaryotes

... parameter in its contribution to membrane structure and stability. Restricted solubility in an aqueous environment is governed by the tendency of acyl chains to remain associated with one another (oil does not dissolve well in water). Similarly, response to temperature is modulated by the extent to ...
Folie 1 - FLI
Folie 1 - FLI

... contains comprising ...
Evolution of the citric acid cycle and respiratory
Evolution of the citric acid cycle and respiratory

... operation of a fumarate reductase system would have become superfluous, at least as far as biosynthesis is concerned. Assuming that the final catalyst needed for completion of the CAC was indeed KGD, we can ask what design characteristics this enzyme should have to ensure effective operation of a bi ...
A Bifunctional tRNA for In Vitro Selection
A Bifunctional tRNA for In Vitro Selection

... pressed in vivo; the cell membrane encapsulates corresponding protein and nucleic acid sequences during complex formation. Ribosome display [7] relies on the integrity of stalled translation complexes to maintain a link between an mRNA and its protein product. With mRNA display [8, 9], covalent prot ...
Poon, Andy: Predicting Phosphorylation: A critique of the NetPhos program and potential alternatives
Poon, Andy: Predicting Phosphorylation: A critique of the NetPhos program and potential alternatives

... (reviewed by Pawson, 2004). Given the prevalence of phosphorylation as a regulatory mechanism in cellular functions, there exists a need to predict whether certain proteins are susceptible to this posttranslational modification. When searching through an amino acid sequence for ...
Plant biotin-containing carboxylases
Plant biotin-containing carboxylases

... considerable heterogeneity of subunits in the holoenzyme. These holoenzymes could have different biochemical properties. In Arabidopsis, single genes code for the BC (At5g35360) [51] and a-CT (At2g38040) [54] subunits, but at least two genes code for the BCC subunit (At5g16390 and At5g15530) [47,50]. ...
WJEC s13-biology1
WJEC s13-biology1

Free radicals and antioxidants
Free radicals and antioxidants

... around the nucleus. (can be atom, ions, molecule). • tend to reach equilibrium, plucks an electron from the nearest intact molecule. • most of biomoleculs are not radicals ...
immuno 2015 - hippocampus
immuno 2015 - hippocampus

... this experiment designed to answer? What do you predict will happen? Your hypothesis should relate to the predicted results..  Do you expect any cell types to contain both GFAP and NF-M?  Do you expect there to be more neurons or more glia?  How can you use the nuclear staining to help determine ...
Factors that affect Drug Metabolism
Factors that affect Drug Metabolism

... into reactive intermediates those covalently bind to DNA, a key event in the initiation of carcinogenesis. Likewise, Cyp 1A2 activates a variety of bladder carcinogens, such as aromatic amines and amides. Also, some forms of cytochrome P450 isozymes such as Cyp 3A and 2E1 activate the naturally occ ...
Effects of monosulfuron-ester on metabolic processes of nitrogen
Effects of monosulfuron-ester on metabolic processes of nitrogen

... nitrogen-fixing cyanobacteria in China agricultural fields.8 In general, cyanobacteria are very sensitive to herbicides because they possess many characteristics of higher plants.9 Previous study showed that cyanobacteria had different degrees of sensitivity to herbicides.10 However, the effect of m ...
Correlation of an Immobilized Digestive Enzyme Assay with Poultry
Correlation of an Immobilized Digestive Enzyme Assay with Poultry

... tide bonds in the sample using acid hydrolysis (24 h), whereas the optimized IDEA SBM kit uses nitrogen combustion analysis (15 min) to calculate a percent protein. Calculation of the IDEA value for both assays uses a parameter in the denominator to provide sample protein comparability. The IDEA SBM ...
Pseudoatom-driven solvent accessibility refinement (PaDSAR) Method
Pseudoatom-driven solvent accessibility refinement (PaDSAR) Method

... Patching and solvating the full-length models with pseudoatoms Two categories of pseudoatoms are introduced in the system, i.e., spin-label pseudoatoms and environment pseudoatoms [1], as summarized in Table 1. The spin-label pseudoatoms are further classified into five different types, denoted EP1, ...
Enzymes speed up metabolic reactions by lowering energy barriers
Enzymes speed up metabolic reactions by lowering energy barriers

... •  Every chemical reaction between molecules involves bond breaking and bond forming •  The initial energy needed to start a chemical reaction is called the free energy of activation, or activation energy (EA) •  Activation energy is often supplied in the form of heat from the surroundings ...
C - IS MU
C - IS MU

... Elastin exhibits a very long biological half-life (the half-life of elastin in the wall of aorta is referred to be about 40 years). After the childbirth, the synthesis of elastin is distinctly reduced, if it is possible at all. The loss of tissue elasticity (namely of skin, large vessels, lung) in ...
6. DNA transcription/translation
6. DNA transcription/translation

... Protein Synthesis • The information content of DNA is in the form of specific sequences of nucleotides along the DNA ...
2. Lect. Urea cycle
2. Lect. Urea cycle

... For example, the malate can be transported into the mitochondria via the malate shuttle, reenter the tricarboxylic acid cycle, and get oxidized to oxaloacetate (OAA), which can be used for gluconeogenesis . Alternatively, the OAA can be converted to aspartate via transamination , and can enter the ...
Characterization of novel canine bocaviruses and their association
Characterization of novel canine bocaviruses and their association

... generating sequence alignments. The most appropriate protein or nucleotide substitution model was determined using MEGA, and the method with lowest scores was used to calculate pair-wise distances and to construct phylogenetic trees (Fig. 2). All three CBoV proteins (NS, NP and VP) were genetically ...
Objective (Local, State, National – College Board)
Objective (Local, State, National – College Board)

... 1.a. Introduce acid-base behavior in terms of ionization. Use light bulb tester to show acids and bases contain conduct electricity because they contain ions. Good conductors are strong acids and bases, weak conductors are weak acids and bases. Arrhenius definitions are based on these observations. ...
structure-sheets-text
structure-sheets-text

... Loops and turns connect α-helices and β strands and allow the polypeptide chain to fold back on itself, producing the compact 3D shape seen in native structures; ...
Regents Chemistry Topic Review Packet
Regents Chemistry Topic Review Packet

... 4. A physical change results in the rearrangement of existing particles in a substance; no new types of particles result from this type of change. A chemical change results in the formation of different particles with changed properties.  Distinguish between chemical and physical changes based on w ...
fae04be7f127386
fae04be7f127386

... synthesized, it is threaded into the translocator in the normal way but cannot leave at the other end because the amino acid residues do not associate with water. As synthesis continues, the newest length of polypeptide bulges into the cytosol. Once synthesis stops, this section is left as the cytos ...
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Biochemistry



Biochemistry, sometimes called biological chemistry, is the study of chemical processes within and relating to living organisms. By controlling information flow through biochemical signaling and the flow of chemical energy through metabolism, biochemical processes give rise to the complexity of life. Over the last decades of the 20th century, biochemistry has become so successful at explaining living processes that now almost all areas of the life sciences from botany to medicine to genetics are engaged in biochemical research. Today, the main focus of pure biochemistry is in understanding how biological molecules give rise to the processes that occur within living cells, which in turn relates greatly to the study and understanding of whole organisms.Biochemistry is closely related to molecular biology, the study of the molecular mechanisms by which genetic information encoded in DNA is able to result in the processes of life. Depending on the exact definition of the terms used, molecular biology can be thought of as a branch of biochemistry, or biochemistry as a tool with which to investigate and study molecular biology.Much of biochemistry deals with the structures, functions and interactions of biological macromolecules, such as proteins, nucleic acids, carbohydrates and lipids, which provide the structure of cells and perform many of the functions associated with life. The chemistry of the cell also depends on the reactions of smaller molecules and ions. These can be inorganic, for example water and metal ions, or organic, for example the amino acids which are used to synthesize proteins. The mechanisms by which cells harness energy from their environment via chemical reactions are known as metabolism. The findings of biochemistry are applied primarily in medicine, nutrition, and agriculture. In medicine, biochemists investigate the causes and cures of disease. In nutrition, they study how to maintain health and study the effects of nutritional deficiencies. In agriculture, biochemists investigate soil and fertilizers, and try to discover ways to improve crop cultivation, crop storage and pest control.
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