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Biology and computers
Biology and computers

... Asterisk represents identity : represents high similarity . represents low similarity ...
Computer-Assisted Molecular Modeling of Benzodiazepine and
Computer-Assisted Molecular Modeling of Benzodiazepine and

... in Table 1. This SAR of BZ inhibition reveals that the nonfused phenyl ring is necessary for activity in our series. The strongest correlation occurs at the 2’-position of that ring. Although there are no compounds in our series differing only at R2’, comparisons between similar compounds show that ...
Chapter 16 Food: Those Incredible Edible Chemicals
Chapter 16 Food: Those Incredible Edible Chemicals

... Chapter 16 ...


... it is in the hydrophobic core. Since this Thr would form an H-bond to water in the unfolded state, it will cost about 20 kJ/mole of instability since a hydrogen bond to water is broken during folding, but not reformed. (6 pts) Additional factors (1 pt for either, unless the main reason was missed an ...
Side-chain hydrophobicity scale derived from transmembrane
Side-chain hydrophobicity scale derived from transmembrane

... amino acids as guests. Position 210 is a lipid-facing exterior residue whose α-carbon is located only 0.2 Å from the midplane between OmpLA’s membrane/water interfacial regions (Fig. 1A). Our membranes were large unilamellar vesicles (LUVs) of 1,2dilauroyl-sn-glycero-3-phosphocholine (DLPC). To dete ...
AP Biology
AP Biology

... be used to date things that died recently in geologic history (under 70,000 years ago). • You can only date organic remains using carbon 14 ...
THE THREE-DIMENSIONAL STRUCTURE OF PROTEINS
THE THREE-DIMENSIONAL STRUCTURE OF PROTEINS

... can theoretically assume countless different conformations, and as a result the unfolded state of a protein is characterized by a high degree of conformational entropy. This entropy, and the hydrogen-bonding interactions of many groups in the polypeptide chain with solvent (water), tend to maintain ...
Role of Pro-297 in the catalytic mechanism of sheep liver... hydroxymethyltransferase
Role of Pro-297 in the catalytic mechanism of sheep liver... hydroxymethyltransferase

... different amino acid residues in substrate binding and catalysis. In addition, both the enzymes catalyse decarboxylation, racemization and transamination, for example, apart from their physiological reaction. Site-directed mutagenesis and X-ray crystallographic studies of AATase had identified Arg-3 ...
CHAPTER 3 STOICHIOMETRY:
CHAPTER 3 STOICHIOMETRY:

... reactants are LR reactions. Convert grams of reactants to moles. Divide the results of each mole on its coefficient in the balanced equation. The smallest value is for the LR substance. Your calculations should be based on the LR. ...
The effecTs of benzoic acid and proTein level on urine ph and
The effecTs of benzoic acid and proTein level on urine ph and

... diet composition and feed efficiency of animals. One of the possibilities to reduce ammonia emissions is through dietary manipulation (Gatel and Grosjean, 1992). Organic acids such as formic acid, lactic acid are added in the diet of pigs (Jongbloed et al., 2000), are readily metabolized in the live ...
Writing and Balancing Chemical Equations
Writing and Balancing Chemical Equations

... 1. The substances undergoing reaction are called reactants, and their formulas are placed on the left side of the equation. 2. The substances generated by the reaction are called products, and their formulas are placed on the right sight of the equation. 3. Plus signs (+) separate individual reactan ...
RMA1, an Arabidopsis thaliana Gene Whose cDNA Suppresses the
RMA1, an Arabidopsis thaliana Gene Whose cDNA Suppresses the

... 15c-10 (RMA1) encodes a novel membrane protein with a RING finger motif—The complete nucleotide sequence of 15c-10 (1,032 bp) was determined. 15c-10 shows no sequence similarity to SEC15, meaning that it is a suppressor of the seclS mutation. The longest ORF of 15c-10 encodes a novel protein of 249 ...
Acid-Base Balance
Acid-Base Balance

... • Explain the way in which the respiratory system aects blood pH Proper physiological functioning depends on a very tight balance between the concentrations of acids and bases in the blood. Acid-balance balance is measured using the pH scale, as shown in Figure 1 (The pH Scale ). A variety of buer ...
Introductary topics
Introductary topics

... with additional hydrogens are named by adding hydrogen (or bi-) for one extra H, dihydrogen (for two extra H), etc., to the name as follows: CO32- is named carbonate, but HCO3- is hydrogen carbonate (or bicarbonate) H2PO4- dihydrogen phosphate anion. ...
X PS EM - deo kadapa
X PS EM - deo kadapa

... When dogs pant, the water molecules present on the tongue and in mouth gets evaporated by absorbing some heat from their body. As a result the interior of dog’s body gets cooled. (3) If you are chilly outside the shower stall, why do you feel warm after the bath if you stay in the bathroom? Ans:- (i ...
Multiple Sequence Alignment
Multiple Sequence Alignment

... Asterisk represents identity : represents high similarity . represents low similarity ...
Fredrik Lysholm Bioinformatic	methods	for	characterization	of viral	pathogens	in	metagenomic	samples Linköping studies in science and technology
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... Virus infections impose a huge disease burden on humanity and new viruses are continuously found. As most studies of viral disease are limited to the investigation of known viruses, it is important to characterize all circulating viruses. Thus, a broad and unselective exploration of the virus flora ...
The Complete Notes - Joliet Junior College
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... remembering. An analogy would be this: you read all the books out there on the subject of golf, but don’t get round to swinging a club – what do you think happens when you tee off for the first time? ...
Michaelis-Menten equation
Michaelis-Menten equation

... (a) the enzyme and both substrates come together to form a ternary complex. In ordered binding, substrate 1 must be bound before substrate 2 can bind productively. (b) an enzyme-substrate complex forms, a product leaves the complex, the altered enzyme forms a second complex with another substrate mo ...
Secretion of Bacillus subtilis a-Amylase in the Periplasmic Space of
Secretion of Bacillus subtilis a-Amylase in the Periplasmic Space of

... The a-amylase structural gene (amyE) of B. subtilis Marburg NA64 has been cloned into PUB1 10 (Takeichi et al., 1983). This plasmid was designated pTUB4 and the DNA sequence of the inserted 2.3 kb fragment is known (Ohmura et al., 1983). pYK33 I(a 'Psi vector') is a derivative of pBR322 containing t ...
disturbances of metabolic homeostasis in liver disease
disturbances of metabolic homeostasis in liver disease

... vate provide approximately half of the precursor requirernent. Some of this lactate, about half, is derived from giucose (the Cori cycle), and therefore does not represent a true de novo glucose precursor. However some of this lactate is derived from glycogen in extrahepatic tissues and provides a m ...
David Rittenberg - National Academy of Sciences
David Rittenberg - National Academy of Sciences

... to talk with other members of the department about possible uses of 2H. These developments have been reviewed comprehensively by the historian Robert E. Kohler (Historical Studies in Physical Sciences, vol. 8, pp. 257-98, R. McCormmach and L. Pyerson, eds., Johns Hopkins University Press, Baltimore, ...
Nutrition and Food Science
Nutrition and Food Science

... Nutrients and non-essential compounds present in foods interact with a number of metabolic pathways. Decoding these complex interactions is challenging as nutrients may subtly interact with multiple targets. Metabolomics can be essential to investigating the role that dietary components play in heal ...
[S], K m
[S], K m

... resulting in catalysis of the reaction. The magnetic interactions provide energy that compensates for the increase in free energy required to bend the stick. Reaction coordinate diagrams show the energetic consequences of complementarity to substrate versus complementarity to transition state. The t ...
VIRTUAL SCREENING OF POTENTIAL DRUG-LIKE INHIBITORS FROM MEDICINAL PLANTS
VIRTUAL SCREENING OF POTENTIAL DRUG-LIKE INHIBITORS FROM MEDICINAL PLANTS

... Dr.Duke’s phytochemical and ethanobotanical databases. The screening of phytochemicals from the database in specific to antiviral activity and anticancer activity is done because HBXIP is an oncogenic and Hepatitis B virus interacting in nature. There were about many repeated compounds present in th ...
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Biochemistry



Biochemistry, sometimes called biological chemistry, is the study of chemical processes within and relating to living organisms. By controlling information flow through biochemical signaling and the flow of chemical energy through metabolism, biochemical processes give rise to the complexity of life. Over the last decades of the 20th century, biochemistry has become so successful at explaining living processes that now almost all areas of the life sciences from botany to medicine to genetics are engaged in biochemical research. Today, the main focus of pure biochemistry is in understanding how biological molecules give rise to the processes that occur within living cells, which in turn relates greatly to the study and understanding of whole organisms.Biochemistry is closely related to molecular biology, the study of the molecular mechanisms by which genetic information encoded in DNA is able to result in the processes of life. Depending on the exact definition of the terms used, molecular biology can be thought of as a branch of biochemistry, or biochemistry as a tool with which to investigate and study molecular biology.Much of biochemistry deals with the structures, functions and interactions of biological macromolecules, such as proteins, nucleic acids, carbohydrates and lipids, which provide the structure of cells and perform many of the functions associated with life. The chemistry of the cell also depends on the reactions of smaller molecules and ions. These can be inorganic, for example water and metal ions, or organic, for example the amino acids which are used to synthesize proteins. The mechanisms by which cells harness energy from their environment via chemical reactions are known as metabolism. The findings of biochemistry are applied primarily in medicine, nutrition, and agriculture. In medicine, biochemists investigate the causes and cures of disease. In nutrition, they study how to maintain health and study the effects of nutritional deficiencies. In agriculture, biochemists investigate soil and fertilizers, and try to discover ways to improve crop cultivation, crop storage and pest control.
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