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Structure, function and regulation of pyruvate carboxylase
Structure, function and regulation of pyruvate carboxylase

... In confirmation of earlier studies on the intracellular localization of PC [53,54], Rohde et al. [55] employed an immunoelectron microscopic approach to show that vertebrate PC is located exclusively in the mitochondrial matrix, close to the mitochondrial inner membrane. Several studies have indicat ...
GROUP 13 ELEMENTS -THE BORON FAMILY -
GROUP 13 ELEMENTS -THE BORON FAMILY -

... oxidation state. The melting point is 29.8º C and therefore melts by increasing room temperature by a little. Gallium is important because it forms gallium arsenide (GaAs), which can convert light directly into electricity. Also due to thermite reaction, aluminum can extract oxygen from water and hy ...
1 Chapter 5
1 Chapter 5

... •Health Promotion (Public Health Agency of Canada): http://www.phac-aspc.gc.ca/hp-ps/index.html •Strategic Inter-Governmental Forum on Physical Activity and Health (SIGPAH): http://www.nphp.gov.au/workprog/sigpah/ •Healthy youth (Centre for disease control and prevention (USA): http://www.cdc.gov/He ...
Cell Biology # 4
Cell Biology # 4

... ribosome movement ribosome. tRNA at the P site is 2c Translocation. As the transferred to the amino entire ribosome translocates, it acid carried by the tRNA shifts by one codon along the mRNA: in the A site, and a new • The unloaded tRNA in the P peptide bond is formed. site is moved to the E site ...
The rate of glycolysis quantitatively mediates specific
The rate of glycolysis quantitatively mediates specific

... Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA Full list of author information is available at the end of the article ...
Measuring enzyme activities under standardized in vivo
Measuring enzyme activities under standardized in vivo

... However, standardization per se is not sufficient. It is crucial that the standards lead to data that are representative of the in vivo condition. In the case of pathway fluxes, in vivo rates can be measured, and it is also possible to measure absolute concentrations of proteins [4] and transcripts [5 ...
Supporting Information
Supporting Information

... densities were well defined except in a few segments that we predict interact with membranes and may become disordered on detergent solubilization. Weak electron density was observed for residues 1–2 and 109–126, so these regions were excluded from the final model. The final model consisted of 96.3% ...
Synaptonemal complex proteins - Journal of Cell Science
Synaptonemal complex proteins - Journal of Cell Science

... the intermediate filament family of proteins. Cor1 protein, like myosin heavy chains, intermediate filament proteins and the pM1 protein, is predicted to have regions of heptad repeats and is therefore likely to form coiled-coil structures. ...
I Semester B.Sc. Examination Paper
I Semester B.Sc. Examination Paper

... b) What is Aufbau principle? c) In the reaction MnO2+4 HC1→MnC12+C12+2H2O, identify the oxidizing and reducing agents. ...
Chemical Equilibrium - Chemistry Teaching Resources
Chemical Equilibrium - Chemistry Teaching Resources

... Unit 3: Chemical Reactions ...
A Review of Issues of Dietary Protein Intake in Humans
A Review of Issues of Dietary Protein Intake in Humans

... had significant limitations, as it consisted of a small sample size (10 normal and 34 cirrhotic subjects), excluded individual differences according to age, sex, previous diet history, training status, and was undertaken more than 30 y ago. The dangers of excessive protein intake should not be under ...
KRAS activity Teachers` notes
KRAS activity Teachers` notes

... Discussion: How does information like this influence our approach to cancer? Use the information below to stimulate discussion on how genomic information can be used to further our understanding of cancer. Discussion points for students: • What experiments or approaches could be used to establish wh ...
To remember Sir Hans Krebs: Nobelist, Friend, and Adviser
To remember Sir Hans Krebs: Nobelist, Friend, and Adviser

... leads to the re-formation of oxaloacetic acid, but allows packets of electrons to be released in small steps that can be strictly controlled. Figure 1 presents an illustration of the Krebs cycle. As Krebs explained in his Nobel prize lecture, “Of major significance was another new observation. Citra ...
Interaction of DNA with ribosomes in cell-free protein
Interaction of DNA with ribosomes in cell-free protein

... after the incubation with DNA. After density gra­ dient centrifugation of unincubated ribosomes or from incubation mictures without DNA, clusters of ribosomes have been found in the position of poly­ somes. These clusters are very sim ilar to polysomes seen in electron m icrographs from other organi ...
Identification, cloning and sequence determination of genes specifying hexokinase A and B from yeast.
Identification, cloning and sequence determination of genes specifying hexokinase A and B from yeast.

... The structural gene for BIB was located by an in vitro assay for glucose phosphorylating activity in extracts of E. coli strain ZSC113 transformed with plasmid vectors carrying subclones of the original plasmid (pRB62). After transformation of ZSC113 with plamid DNA, antibiotic resistant colonies we ...
Darwin and evolution: a set of activities based on the evolution of
Darwin and evolution: a set of activities based on the evolution of

... from the order Perissodactyla), and the leopard (Carnivora). All these are in the blue section of the evolutionary tree shown in Figure 1. Also included are some more distantly related mammals, from orders in the green section of the tree: human, rabbit and mouse. Ideally, these sequences would be p ...
Chapter 11
Chapter 11

... • Under anaerobic conditions the conversion of glucose to pyruvate is much higher than under aerobic conditions (yeast cells produce more ethanol and muscle cells accumulate lactate) • The Pasteur Effect is the slowing of glycolysis in the presence of oxygen • More ATP is produced under aerobic cond ...
Transamination and asymmetry in glutamate transport across the
Transamination and asymmetry in glutamate transport across the

... Alanine washout from the vascularly preloaded epithelium (mean Kexit [fast, unstripped] = 0.181 + 0.051 min -t) is similar to exit from t h e e p i t h e l i u m a f t e r loading from the lumen (mean Kexit [fas% unstripped] = 0.150 + 0.008 min-t). However~ glutamate washout from t h e v a s c u l a ...
Enzymes and food flavor : a review
Enzymes and food flavor : a review

... public concern for the total wholesomeness and chemical safety of food ingredients (Basset,l990). From a total world market of 6 billion dollars for the flavor and fragrance industry in 1990, food flavors account for 25%,with about 5% annual growth rate (Cheetham 1991). Flavor sales were estimated t ...
RNA is synthesized by a DNA-dependent RNA polymerase (uses
RNA is synthesized by a DNA-dependent RNA polymerase (uses

... transcription is illustrated in figure below. • RNA polymerase locates genes in DNA by searching for promoter regions. The promoter is the binding site for RNA polymerase. Binding establishes where transcription begins, which strand of DNA is used as the template, and in which direction transcriptio ...
Lesson Overview
Lesson Overview

... • Also called the Calvin Cycle • Calvin Cycle- a series of reactions that produces the organic molecule (carbohydrates). • Occurs in the stroma (open space) of the chloroplast • The light-independent reaction is a continuous chain of chemical reactions in which energy is used to convert CO2 ...
Fibrous Proteins
Fibrous Proteins

...  Signal sequence directs growing polypeptide chain into the cisternae of the rough ER  The signal sequence facilitates the binding of ribosomes to the RER and directs the passage of pre pro chain in thr RER. ...
Absorption Spectroscopy
Absorption Spectroscopy

... The alpha-carbon in the protein backbone is an asymmetric atom (except in glycine), which makes it optically active, and the backbone dominates the CD spectrum of proteins. The CD spectrum is most interesting in the region between 160-220 nm, though typically the spectrum is more easily interpreted ...
Concepts of Biology
Concepts of Biology

... Creative Commons Attribution 4.0 International License (CC-BY). ...
In chemistry, a salt is an ionic compound that
In chemistry, a salt is an ionic compound that

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Biochemistry



Biochemistry, sometimes called biological chemistry, is the study of chemical processes within and relating to living organisms. By controlling information flow through biochemical signaling and the flow of chemical energy through metabolism, biochemical processes give rise to the complexity of life. Over the last decades of the 20th century, biochemistry has become so successful at explaining living processes that now almost all areas of the life sciences from botany to medicine to genetics are engaged in biochemical research. Today, the main focus of pure biochemistry is in understanding how biological molecules give rise to the processes that occur within living cells, which in turn relates greatly to the study and understanding of whole organisms.Biochemistry is closely related to molecular biology, the study of the molecular mechanisms by which genetic information encoded in DNA is able to result in the processes of life. Depending on the exact definition of the terms used, molecular biology can be thought of as a branch of biochemistry, or biochemistry as a tool with which to investigate and study molecular biology.Much of biochemistry deals with the structures, functions and interactions of biological macromolecules, such as proteins, nucleic acids, carbohydrates and lipids, which provide the structure of cells and perform many of the functions associated with life. The chemistry of the cell also depends on the reactions of smaller molecules and ions. These can be inorganic, for example water and metal ions, or organic, for example the amino acids which are used to synthesize proteins. The mechanisms by which cells harness energy from their environment via chemical reactions are known as metabolism. The findings of biochemistry are applied primarily in medicine, nutrition, and agriculture. In medicine, biochemists investigate the causes and cures of disease. In nutrition, they study how to maintain health and study the effects of nutritional deficiencies. In agriculture, biochemists investigate soil and fertilizers, and try to discover ways to improve crop cultivation, crop storage and pest control.
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