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for meta-analysis
for meta-analysis

... The U.S. Food and Drug Administration advisory panel supported this empiric recommendation of 12 months DAPT after DES placement and determined that these guidelines be incorporated into DES product labeling. This recommendation was not based on any prospective randomized trial evidence associating ...
summary of product characteristics
summary of product characteristics

... The dose of buprenorphine should be increased progressively according to the clinical effect of the individual patient and should not exceed a maximum single daily dose of 24 mg. The dosage is titrated according to reassessment of the clinical and psychological status of the patient. Distribution of ...
Characterization of the Effects of the Partial Dopamine Agonist
Characterization of the Effects of the Partial Dopamine Agonist

... mg/kg IV), 2 had received acute intracerebral microinfusion of aminophosphonovaleric acid (1.5–3.0 mg in the nucleus accumbens), one had been exposed to both dextromethorphan and the substitution study and one had been exposed to both dextromethorphan and gamma-hydroxybutyrate. Finally, of the 41 ra ...
Australian public assessment for vortioxetine hydrobromide
Australian public assessment for vortioxetine hydrobromide

... During the course of evaluation by the TGA, vortioxetine was approved in the USA (30 September 2013) and the EU (18 December 2013). The Australian indication requested by the sponsor is somewhat different from that requested in other jurisdictions. The sponsor indicated that this difference was due ...
ABSTRACT DOSIMETRIC STUDY OF BETA
ABSTRACT DOSIMETRIC STUDY OF BETA

... high doses of radiation to the tumor, while sparing surrounding healthy tissues. Because it is highly targeted, brachytherapy presents lower risks of side effects due to radiation and is usually well tolerated. Brachytherapy can be used in combination with other techniques, such as external beam rad ...
(NSAIDs) classification, diagnosis and management
(NSAIDs) classification, diagnosis and management

... from 0.5% to 1.9% of the general population (5, 6). Prevalence of hypersensitivity to NSAIDs among adult asthmatic patients assessed by questionnaires or medical records is ranging from 4.3% to 11% (7) and can be as high as 21% if diagnosis includes provocation tests (8). Among patients with bronchi ...
DIPHENHYDRAMINE HYDROCHLORIDE
DIPHENHYDRAMINE HYDROCHLORIDE

... MAO inhibitors prolong and intensify the anticholinergic (drying) effects of antihistamines. Carcinogenes is , Mutagenes is , Impairment of Fertility Long-term studies in animals to determine mutagenic and carcinogenic potential have not been performed. Pregnancy Pregnancy Category B Reproduction st ...
Clavulin
Clavulin

... If an allergic reaction occurs, the administration of CLAVULIN® should be discontinued and appropriate therapy should be instituted. Serious anaphylactoid reactions require immediate emergency treatment with epinephrine. Oxygen, intravenous steroids and airway management, including intubation should ...
Physician`s Labeling Rule_Content
Physician`s Labeling Rule_Content

... included (in overlapping categories) open-label and double-blind phases of studies, inpatients and outpatients, and short-term and longer-term exposure. Adverse reactions were assessed by collecting adverse events, results of physical examinations, vital signs, weights, laboratory analyses, and ECGs ...
Lay summary Page 2 Scientific discussion
Lay summary Page 2 Scientific discussion

... The application was submitted as an abridged application according to Article 10.1 of EC Directive 2001/83. The cross reference product is Zirtek Solution (PL 08972/0033), granted to UCB S.A on 19 July 1993, changing ownership to UCB Pharma Ltd on 5 May 2000. As the cross-reference product was grant ...
2% XylocaineDENTAL with epinephrine 1:50000
2% XylocaineDENTAL with epinephrine 1:50000

... Studies of lidocaine in animals to evaluate the carcinogenic and mutagenic potential or the effect on fertility have not been conducted. PREGNANCY Teratogenic Effects : Pregnancy Category B. Reproduction studies have been performed in rats at doses up to 6.6 times the human dose and have revealed no ...
Antifungal drugs and resistance: Current concepts
Antifungal drugs and resistance: Current concepts

... such as Majocchi granuloma. The preferred treatment for tinea imbricata is griseofulvin or terbinafine, although some resistance has developed to oral griseofulvin [34]. The mode of action of griseofulvin is not completely clear, but it has been speculated that griseofulvin inhibits microtubule bind ...
IV INFUSION MINI MANUAL TABLE OF CONTENTS IV INFUSION
IV INFUSION MINI MANUAL TABLE OF CONTENTS IV INFUSION

... 15. Would a simultaneous infusion of two bags of chemo drugs be billed as a concurrent infusion? a. No, you can submit separate hourly administration charges for each bag of chemo drug even though they are administered simultaneously. b. Assuming the chemo is your primary service, you would charge f ...
Dr. Reyes' presentation slides
Dr. Reyes' presentation slides

... • Can be mildly sedating • Nausea/vomiting, dizziness, diarrhea, tingling sensation • Liver toxicity (<1% vs 1.8%?), • Females >30 yrs old taking >300 mg/day for more than  60 days • Usually reversible; fatality <0.3% • Not felt to be safe for use in people with liver  dysfunction • Therefore, use l ...
cycloSPORINE Monograph
cycloSPORINE Monograph

... therapy should be temporarily withheld or discontinued in patients with signs and symptoms of myopathy or at risk of severe renal injury secondary to rhabdomyolysis.4 See Drug Interaction table. Nervous system effects are numerous and may be associated with high cyclosporine blood concentrations, co ...
Urine Drug Testing Practices - Canadian Nuclear Safety Commission
Urine Drug Testing Practices - Canadian Nuclear Safety Commission

... The screening and confirmation cut-off values used in different programmes are not always identical and these cut-off values are modified over time as new information about drug metabolism and excretion is published and technological advances are available in the laboratory. It is important to appre ...
Outcome Measures - Multidisciplinary Association for Psychedelic
Outcome Measures - Multidisciplinary Association for Psychedelic

... treated for free a total of 31 people from January 2003 to June 2004, when it closed for lack of additional funds. Preliminary anecdotal results were obtained from this period and were somewhat promising, suggesting a need for further data collection. The Iboga Therapy House is now a project of the ...
contents - Médecins d`Afrique
contents - Médecins d`Afrique

... carried out in the absorbance mode at 315 nm. The linear regression analysis data for the calibration plots showed good linear relationship with r2 =0.9922 in the concentration range 300-1000 ng per spot. The mean value of correlation coefficient, slope and intercept were 0.99220.002, 0.0640.001 a ...
FORMULATION AND EVALUATION OF ORAL FAST DISSOLVING TABLETS OF SILDENAFIL  CITRARTE  Research  Article   
FORMULATION AND EVALUATION OF ORAL FAST DISSOLVING TABLETS OF SILDENAFIL  CITRARTE  Research  Article   

... one,  which  immediately  attains  the  desired  therapeutic  concentration  of  drug  in  plasma  (or  at  the  site  of  action)  and  maintains  it  constant  for  the  entire  duration  of  treatment.  This  is  possible  through  administration  of  conventional  dosage  form  in  a  particular ...
norspan® transdermal patch - Research Review Australia
norspan® transdermal patch - Research Review Australia

... NORSPAN® patch application resulted in transient decreases in blood pressure in healthy young and elderly subjects, without clinical adverse events. Respiratory depression is less common than with full mu-agonists, such as morphine, and there appears to be a ceiling effect. When respiratory depressi ...
Atrovent - Boehringer Ingelheim
Atrovent - Boehringer Ingelheim

... there are no formal studies fully evaluating the interaction effects of ATROVENT Inhalation Aerosol and these drugs with respect to effectiveness. Anticholinergic agents: Although ipratropium bromide is minimally absorbed into the systemic circulation, there is some potential for an additive interac ...
% 4 L Memorandum
% 4 L Memorandum

... this dietary ingredient, when used under the conditions suggested in the labeling of the dietary supplement, is reasonably expected to be safe. These supporting studies include: ...
Subetta treatment increases adiponectin secretion by - Zen-Bio
Subetta treatment increases adiponectin secretion by - Zen-Bio

... [13]. For the first time in the study of the repeated dilution process, it was found that the resulting ultra-dilution generates a novel activity absent in the starting material, called a release-activity. A distinctive feature of the release-active antibodies is their ability not to suppress, and t ...
P otective  effects  of  inhaled  ipratropium ... on  bronchoconstriction  induced  by  adenosine
P otective effects of inhaled ipratropium ... on bronchoconstriction induced by adenosine

... was carried out to derive the PD20 value as already described. On the second occasion, a bronchial provocation test with inhaled methacholine was undertaken in a similar manner and the corresponding PD20 values derived. ...
CYMBALTA  (duloxetine hydrochloride) Delayed-release Capsules
CYMBALTA (duloxetine hydrochloride) Delayed-release Capsules

... The efficacy of Cymbalta as a treatment for depression was established in 4 randomized, double-blind, placebo-controlled, fixed-dose studies in adult outpatients (18 to 83 years) meeting DSM-IV criteria for major depression. In 2 studies, patients were randomized to Cymbalta 60 mg once daily (N=123 ...
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