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formulation and evaluation of mouth dissolving tablets
formulation and evaluation of mouth dissolving tablets

... *e-mail:[email protected] ...
p-values from Fisher`s/Chi square test
p-values from Fisher`s/Chi square test

... independent but correlated within the same patients. The results were considered significant at a level less than 0.05. All analyses were conducted using SAS® versions 9.2 (SAS Institute Inc., Cary, NC, USA). All results were reported using the table shells included in the Appendix section of this d ...
Rx and OTC medications containing acetaminophen
Rx and OTC medications containing acetaminophen

... Serious, life-threatening, or fatal respiratory depression has been reported with the use of opioids, even when used as recommended. While serious, life-threatening, or fatal respiratory depression can occur at any time during the use of XARTEMIS XR, the risk is greatest during the initiation of the ...
Zyban SPC (Mar 15)
Zyban SPC (Mar 15)

... Inappropriate routes of administration Zyban is intended for oral use only. The inhalation of crushed tablets or injection of dissolved bupropion has been reported, and may lead to a rapid release, faster absorption and a potential overdose. Seizures and/or cases of death have been reported when bup ...
Wrath Thor UNSIN
Wrath Thor UNSIN

... regions of the brain, including the OFC.9 The DRN was considered as a potential locus of intervention, however, targeting the DRN presented several challenges. The main function of the DRN is to project serotonin to the rest of the brain. It contains the highest concentration of serotonin receptors ...
formulation and evalution of medicated chewing gum of
formulation and evalution of medicated chewing gum of

... Chewing Gum has been used for centuries to clean the mouth and freshen breath. Medicated Chewing Gums are solid, single dose preparations with a base consisting mainly of gum that is intended to be chewed but not swallowed. They contain one or more active substance which released by chewing and are ...
The efficacy and toxicity of Methotrexate (MTX) monotherapy vs
The efficacy and toxicity of Methotrexate (MTX) monotherapy vs

... combination responses were significantly greater than monotherapy [WMD -6.57 (95% CI -8.84 to -4.30), WMD -3.46 (95% CI-4.84 to -2.08), WMD -9.72 (95% CI-14.70 to 4.75), WMD -11.57 (95% CI-19.31 to -3.83), WMD -12.10 (95% CI-19.84 to -4.36) and WMD -0.28 (95% CI -0.36 to -0.21) respectively]. Howeve ...
Slide 1 - The Ophthalmology Report 2013
Slide 1 - The Ophthalmology Report 2013

... groups in terms of the number of eyes that lost or gained  15 letters of visual acuity. » Patients randomized to as-needed treatment with bevacizumab received more injections (mean, 7.7) than did those given as-needed ranibizumab (mean, 6.9). ...
Reassessing Bioavailability of Silymarin
Reassessing Bioavailability of Silymarin

... hepatoprotective, antioxidant, anti-inflammatory, anticancer, and cardioprotective. Although clinical trials have shown silymarin is safe at high doses (>1500 mg/day) in humans, the pharmacokinetic studies over the past three decades related to absorption, distribution, metabolism, and excretion of ...
Targeted therapy in CML
Targeted therapy in CML

... – Provides immunosuppression to allow donor cells to engraft, while graft-versus-leukemia effect eradicates tumor – Permits SCT use in patients not eligible for conventional SCT – Is still investigational ...
NIH Public Access
NIH Public Access

... startle. This effect was not retained at the retention test 2 days later, suggesting it was dependent on acute effects of the drug. Our findings implicate that facilitation of the CB1 or NMDA system with the substances used in this study does not affect conditioned fear extinction lastingly in healt ...
IOSR Journal Of Environmental Science, Toxicology And Food Technology (IOSR-JESTFT)
IOSR Journal Of Environmental Science, Toxicology And Food Technology (IOSR-JESTFT)

... significant increases (≤ 0.001) in serum creatine kinase isoenzyme (CK-MB), cardiac troponin T (cTnc T), lactate dehydrogenase (LDH) and aspartate aminotransferase (AST) activity levels. Cardiac tissue of rats treated with imatinib showed significantly increased cardiac MDA production level and sign ...
September 18, 2014
September 18, 2014

... to rash in patients using PREZISTA®/rtv was 0.5%. Darunavir contains a sulfonamide moiety. PREZISTA® should be used with caution in patients with a known sulfonamide allergy. In clinical studies with PREZISTA®/rtv, the incidence and severity of rash was similar in patients with or without a history ...
Paper Size: H 50 cm x W 48 cm
Paper Size: H 50 cm x W 48 cm

... Initiate treatment with a daily dose of 20 mg/kg in 2 divided doses (10 mg/kg twice daily). Increase the daily dose in 2 weeks by an increment of 20 mg/kg to the recommended daily dose of 50 mg/kg (25 mg/kg twice daily). If a patient cannot tolerate a daily dose of 50 mg/kg, the daily dose may be re ...
3'-Azido-3'-Deoxythymidine (GMM-14) and in Combination with Lamivudine and Nevirapine (GMM-16)
3'-Azido-3'-Deoxythymidine (GMM-14) and in Combination with Lamivudine and Nevirapine (GMM-16)

... malignant lymphoma may have been related to AZT administration for 30 weeks. • There was equivocal evidence of carcinogenic activity of AZT in female heterozygous F1 p53+/– mice based on the occurrence of malignant lymphoma after 45 weeks of administration. ...
NIMODIPINE USE IN M.E. / CFS Page 1 N I M O D I P I N E use in
NIMODIPINE USE IN M.E. / CFS Page 1 N I M O D I P I N E use in

... She has described her use of the drug. "On the fourth day...I was feeling very ill.... On the fifth day...I felt an upswell of energy and had started to feel much better." Her mental activity improved to such a point that she was able to return to professional activity. She cautions that it is very ...
Ceftriaxone
Ceftriaxone

... No impairment of renal function has so far been observed after concurrent administration of large doses of Rocephin and potent diuretics (e.g. furosemide). There is no evidence that Rocephin increases renal toxicity of aminoglycosides. No effect similar to that of disulfiram has been demonstrated af ...
Optimal asthma control, starting with high doses of inhaled budesonide
Optimal asthma control, starting with high doses of inhaled budesonide

... controlled asthma can be further improved with a starting dose of inhaled budesonide higher than that recommended in international guidelines. The study had a parallel-group design and included 61 subjects with poorly controlled asthma, randomized to receive 3,200 mg or 1,600 mg budesonide daily by ...
DRUG NAME: Pamidronate
DRUG NAME: Pamidronate

... 5. Brincker H, Westin J, Abildgaard N, et al. Failure of oral pamidronate to reduce skeletal morbidity in multiple myeloma: a doubleblind placebo-controlled trial. Danish-Swedish co-operative study group. Br J Haematol 1998;101(2):280-286. 6. Novartis Pharmaceuticals Canada Inc. AREDIA® product mono ...
Effects of amiodarone on thyroid function
Effects of amiodarone on thyroid function

... Amiodarone is an iodine rich drug commonly used in the treatment of many cardiac tachyarrhythmias. But it has multiple effects on the thyroid which include abnormalities of thyroid function tests, hypothyroidism and thyrotoxicosis. Although the widely used antiarrythmic in Sri Lanka, the clinical im ...
Ritalin Ritalin-SR
Ritalin Ritalin-SR

... the year) have a temporary slowing in growth rate (on average, a total of about 2 cm less growth in height and 2.7 kg less growth in weight over 3 years), without evidence of growth rebound during this period of development. Published data are inadequate to determine whether chronic use of amphetami ...
Investigating the Efficacy and Anti-Resistance Activity
Investigating the Efficacy and Anti-Resistance Activity

... poor or developing countries and which do not get as much as attention as the ‘big three’: malaria, tuberculosis and HIV/AIDS. HAT specifically affects coutries in Sub-Saharan Africa and is caused by a parasitic protozoa, Trypanosoma brucei. There are two stages of HAT: the early haemolymphatic and ...
DEMEROL (meperidine hydrochloride
DEMEROL (meperidine hydrochloride

... DEMEROL is used with benzodiazepines or other CNS depressants (including alcohol and illicit drugs). Advise patients not to drive or operate heavy machinery until the effects of concomitant use of the benzodiazepine or other CNS depressant have been determined. Screen patients for risk of substance ...
Explanation and elaboration document (WORD, 855KB)
Explanation and elaboration document (WORD, 855KB)

... some cases the suggested formulation is an alternative to the already provided suggestion by Swissethis. Any suggestions are welcome and should be sent to [email protected]. ...
Ketofol_in_the_ED
Ketofol_in_the_ED

... Willman EV, Andolfatto G. A Prospective Evaluation of “Ketofol” (Ketamine/Propofol Combination) for Procedural Sedation and Analgesia in the Emergency Department. Ann Emerg Med. 2007; 49(1): 23-30. Andolfatto G, Willman E. A Prospective Case Series of Single-syringe Ketamine-Propofol (Ketofol) for E ...
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